Guesthouse vacation rentals in Knox County

Find and book unique guesthouse rentals on Airbnb

Top-rated guesthouse rentals in Knox County

Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

0 of 0 items showing

1 of 3 pages

Top guest favorite

The exterior of the Tree House showcases a modern architectural design with large windows that invite natural light. A welcoming porch extends from the unit, featuring wooden railings and hanging wind chimes, surrounded by lush greenery.

Guesthouse in Oak Ridge

4.98 out of 5 average rating, 381 reviews

The "Tree House" - Privacy, Luxury, Nature Views

The elegant "Tree House'' is not in a tree but feels like it, with large windows overlooking lush forest or mountain views. This 450 sf space is a separate unit with own entrance & porch--no stairs! Queen bed, sofa, stone/tile bathroom & walk-in shower, washer-dryer, big TV, fast WiFi, birdfeeders at window. Located on cozy cul-de-sac, reserved parking. This architect-designed space has a kitchenette with fridge, toaster oven, microwave, Keurig coffee, more. Hiking trails near by! Non-smoking.

Guest favorite

A wide driveway leads to a detached garage, flanked by stone columns with decorative lighting. Two recycling bins are placed along the left side, with grassy areas surrounding the concrete driveway. Trees are visible in the background, contributing to the suburban setting.

Guesthouse in Maryville

4.92 out of 5 average rating, 169 reviews

Relax in a Smoky Mtn getaway near Knoxville

Welcome to our centrally located residence! Explore Pigeon Forge & Gatlinburg (1hr away), perfect for motorcycle enthusiasts with easy access to Tail of the Dragon and Foothills Parkway. Nearby bike/walking paths, 30min to downtown Knoxville, and 4 miles from the airport. Restaurants, fast food, and shopping within 15 minutes. Please note that ALL outdoor spaces are SHARED with your host. We respect your privacy and won't intrude on your grilling or swimming experience. Smoking is not allowed.

Superhost

An inviting country guesthouse is illuminated softly against a dark sky filled with clouds. A staircase leads to the upper deck, where warm light spills out from the windows. Subtle outdoor lighting enhances the surrounding lawn, creating a serene atmosphere.

Guesthouse in Mascot

4.84 out of 5 average rating, 515 reviews

Quaint country cottage

A newly remodeled country gusthouse with one bedroom, 1 bath. It has a fully stock kitchen, bathrooms, and linens. Comes with Wi-Fi and two televisions with DIRECTV. you'll be 5 minutes to House Mountain Park, with 527 acres of breathtaking views, trails, picnic area, free parking, and public restrooms. 20 minutes to Downtown Knoxville, Exit 407, featuring The Great Smokey Mountains, Gatlinburg, Dollywood, & The Sky Bridge also 25 min. to 4 lakes Cherokee/Douglas/Norris & Ft. Loudon.

Top guest favorite

A charming modern log house is nestled among trees, featuring a metal roof and a welcoming porch. Surrounding greenery and landscaped flower beds enhance the natural setting, providing a serene entrance to the home.

Guesthouse in Maryville

4.98 out of 5 average rating, 213 reviews

Little River Cabin in the Woods

Upon your arrival to this secluded setting, you will find a charming modern log house. No detail has been overlooked in the decor and furnishings to make you feel at home. On the main floor is a generous living area which includes a contemporary kitchen with many amenities, a bathroom with a walk-in shower and a laundry room, if needed. Up the staircase is the loft with a king size bed, a twin XL daybed and a sleeper sofa. Please note: this property is unsuitable for infants or children.

Top guest favorite

The living area is adorned with a cozy black leather couch and a wooden coffee table atop a patterned rug. A large television is mounted on the wall, opposite a spacious bed visible in the background, with double doors leading to an outdoor deck.

Guesthouse in Powell

4.99 out of 5 average rating, 215 reviews

Private Guesthouse—serene & conveniently located!

Surrounded by woods, this peaceful studio guesthouse provides a retreat-like setting close to our vibrant downtown. The private quarters feature granite countertops, fully-stocked kitchen, separate entrance, comfy bed, sun-filled rooms & a lovely, outdoor seating area to enjoy the quiet. *4 min to Kroger grocery & restaurants *6 min to Tennova North Hospital—perfect for travel nurses! *12 min to downtown *16 min to UT's Neyland Stadium & Thompson Boling Arena *1 hr to the Smoky Mountains

Top guest favorite

A charming pathway leads to a separate entrance of the cottage, bordered by lush greenery and potted plants. The white exteriors of the building contrast with natural elements, creating a serene atmosphere. Steps guide the way to an additional entry, enhancing accessibility.

Guesthouse in Knoxville

4.97 out of 5 average rating, 36 reviews

The Burrow • A Fountain City Cottage

Burrowed in the trees just enough to feel secluded, but close to everything Knoxville has to offer, this little gem will feel like home the second you step inside. While you share a driveway with the host, the house is completely separate. Less than 15 minutes from UT campus, Thompson Boling Arena, and Neyland Stadium. Less than 30 miles to Pigeon Forge and just a little farther to Gatlinburg and the Smokies. 5 minutes to groceries, restaurants and coffee 10 minutes or less to shopping

Guest favorite

A spacious driveway is shown in front of a newly built unit, surrounded by lush greenery. The home features a covered porch and ample parking space, including a visible red vehicle. Trees provide natural shade, contributing to a serene environment.

Guesthouse in Knoxville

4.88 out of 5 average rating, 66 reviews

Ball Camp Hill

Your family will be centrally located when you stay at Ball Camp Hill. Enjoy your stay with country living and city life. You will stay in a secluded area surrounded by nature; at times you can see the wild turkeys and deer strolling through. You will only be a few minutes away from Turkey Creek shopping center. We have several Medical Centers within a few minutes. Pigeon Forge and Gatlinburg are only 50 minutes away. We are only 15 minutes from downtown, market square and UT stadium.

Top guest favorite

A quaint stone guesthouse is surrounded by trees, featuring a gabled roof and a covered front porch. Two windows are symmetrically placed on the facade, allowing natural light into the interior. A chimney is visible on the roof, indicating a cozy ambiance.

Guesthouse in Knoxville

4.96 out of 5 average rating, 314 reviews

*MINUTES to DOWN TOWN *MOUNTAIN VIEWS*PETS OK*

Our Walnut Grove Guest House is on 6.5 acres w/ 360 degrees of privacy & breath-taking views of the Smoky Mountains. Located in Fountain City, we are minutes to downtown Knoxville, & surrounded by shops & restaurants. We are close to many activities & a short drive to the Mountains, Dollywood, Pigeon Forge & Gatlinburg. You’ll love our place because of the coziness, the views, & the location. Our place is good for couples, solo adventurers, business travelers, & families (with kids).

Superhost

A modern kitchen is highlighted by a stylish stainless steel faucet above a granite countertop. In the background, large windows invite natural light, showcasing a cozy seating area with a lamp and armchair, creating a warm and functional space.

Guesthouse in Knoxville

5 out of 5 average rating, 3 reviews

A Modern Rustic Retreat

Tucked into the woods, minutes from the lake, this custom designed private apartment is loaded with amenities and modern style! Press reset and watch the deer feed out the large windows, relax in or by the pool in season or by the bar to unwind. Just minutes from parks, marinas, the lake and a just few minutes more, all the shopping and restaurants you will need out West! Fully equipped kitchen, wifi, office space, washer/dryer, private entry and owners across the yard! Pet Friendly!

Top guest favorite

The entrance features a white door framed by a decorative wrought iron security door, adorned with a green wreath. A small wooden table is positioned beside the door, flanked by lush greenery and a potted plant on the step.

Guesthouse in Knoxville

4.95 out of 5 average rating, 195 reviews

Private North Knox Guesthouse - close to downtown

In the middle of beautiful trees, this peaceful studio guesthouse provides a refreshing setting very close to downtown. The private quarters feature fresh white linens, fully-stocked kitchen, separate entrance, comfy bed, sun-filled rooms & a lovely, outdoor seating area. *4 min to Kroger grocery & restaurants *11 min to Tennova North Hospital, perfect for travel nurses! *12 min to downtown *13 min to UT's Neyland Stadium & Thompson Boling Arena *50 min to the Smoky Mountains

Guest favorite

A wooden deck features a hot tub surrounded by a shaded seating area with colorful cushions. Nearby, a hammock stand is visible, and the lush greenery of the backyard complements the serene setting. The space invites relaxation and enjoyment of the outdoors.

Guesthouse in Knoxville

4.92 out of 5 average rating, 723 reviews

New Studio! Foam Bed, Hot Tub, Close to Downtown!

Studio apartment with lofted queen fully-foam mattress, full kitchen with open concept living space in gorgeous historic neighborhood and mile-long riverside park 2 blocks from home, 5 minute uber ride to downtown Knoxville, 1 block from an amazing restaurant (Plaid Apron) and coffee shop (Treetop Coffee), dog friendly with fenced in backyard, and large back deck with hot tub! Close to the University of Tennessee campus, World's Fair Park and Downtown Knoxville.

Top guest favorite

An outdoor deck is furnished with a seating area that includes two armchairs, a loveseat, and a fire table. A dining table for two is situated nearby, shaded by a blue umbrella. The deck is surrounded by lush greenery, enhancing the natural setting.

Guesthouse in Maryville

4.99 out of 5 average rating, 147 reviews

Little River Guesthouse at Wildwood Rd.

Bring your fishing rods and kayaks! You will want to extend your stay at this Little River oasis. We built this guesthouse just for visiting guests to enjoy. It has been professionally decorated with handpicked items including some nice vintage and antique finds. Enjoy your morning cup of coffee on the huge deck overlooking the river. This home is close to everything including the Knoxville airport, the Smoky Mountains, Pigeon Forge and Gatlinburg.