
Guesthouse vacation rentals in Jacksonville
Find and book unique guesthouse rentals on Airbnb
Top-rated guesthouse rentals in Jacksonville
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Jacksonville guesthouse rentals
Family-friendly guest house rentals

Charming Retreat – Welcome to La Casita

Loft Guest House

Captain's Quarters Tiny House

Sunshine Guesthouse

Treetop Carriage Apartment

Loft in the trees

Luxury Cottage with River Access

Springfield Loft
Guest house rentals with a patio

The Little House

Beach Bliss Hideaway: 1bd Gem!

Adorable 2 Bedroom Cottage

Palm Valley Pool House

Transforms, Full Kitchen/bath, Centrally located

The Moody Loft (Murray Hill)

little dream

Mother-in-law suh-WEET
Guest house rentals with a washer and dryer

Charming Pet-Friendly Guesthouse in Avondale

Private Apartment

La Casita Chiquita Near Events & Entertainment!

The Funk House-A Retreat

Graceful Southern Guesthouse + Outdoor Living Area

Stylish Bungalow Near Dining,Parks & Entertainment

Spacious 2/1 in historic walkable neighborhood

Serene Getaway at the White House
Quick stats about guesthouse rentals in Jacksonville
Total rentals
160 properties
Nightly prices starting at
€ 17 before taxes and fees
Total number of reviews
17K reviews
Family-friendly rentals
10 properties are a good fit for families
Pet-friendly rentals
50 properties allow pets
Rentals with a pool
10 properties have a pool
Destinations to explore
- Seminole Vacation rentals
- Central Florida Vacation rentals
- Orlando Vacation rentals
- Saint Johns River Vacation rentals
- Atlanta Vacation rentals
- Myrtle Beach Vacation rentals
- Destin Vacation rentals
- Tampa Vacation rentals
- Kissimmee Vacation rentals
- Panama City Beach Vacation rentals
- Charleston Vacation rentals
- Four Corners Vacation rentals
- Rentals with a fireplace Jacksonville
- Rentals with a washer and dryer Jacksonville
- Rentals with breakfast Jacksonville
- Rentals with a hot tub Jacksonville
- Villa rentals Jacksonville
- Rentals with lake access Jacksonville
- Rentals with a patio Jacksonville
- Condo rentals Jacksonville
- Mansion rentals Jacksonville
- Fitness-friendly rentals Jacksonville
- RV rentals Jacksonville
- Rentals with an EV charger Jacksonville
- Rentals with a home theater Jacksonville
- Rentals with a kayak Jacksonville
- Apartment rentals Jacksonville
- Beach house rentals Jacksonville
- Pet-friendly rentals Jacksonville
- Waterfront rentals Jacksonville
- Beachfront rentals Jacksonville
- Rentals with beach access Jacksonville
- Smoking-friendly rentals Jacksonville
- Private suite rentals Jacksonville
- Family-friendly rentals Jacksonville
- House rentals Jacksonville
- Rentals with a fire pit Jacksonville
- Townhouse rentals Jacksonville
- Rentals with outdoor seating Jacksonville
- Tiny house rentals Jacksonville
- Hotel rentals Jacksonville
- Rentals with pools Jacksonville
- Rentals with an accessible height toilet Jacksonville
- Guesthouse rentals Duval County
- Guesthouse rentals Florida
- Guesthouse rentals United States
- Ponte Vedra Beach
- TIAA Bank Field
- San Sebastian Winery
- Vilano Beach
- Boneyard Beach
- Crescent Beach
- Kathryn Abbey Hanna Park
- Lightner Museum
- Fountain of Youth Archaeological Park
- Butler Beach
- Pablo Creek Club
- Eagle Landing Golf Club
- Adventure Landing Jacksonville Beach
- Matanzas Beach
- Amelia Island State Park
- Stafford Beach
- St. Augustine Alligator Farm Zoological Park
- Ravine Gardens State Park
- Bent Creek Golf Course
- Black Rock Beach
- Amelia Island Lugar Lindo
- Seminole Beach
- Museum of Southern History
- Little Talbot