Vacation rentals in Islandton

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Top-rated vacation rentals in Islandton

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
Home in Varnville

Hank and Margie's Place

“PEACEFUL!! Nestled in the Lowcountry, a COZY LOOK AND Big City FEEL” – “Hank and Margie’s Place” This home is in a charming quiet neighborhood off Hwy 63/ 64, at the end of a cul-de-sac. "Perfect" for traveling construction/maintenance crews, health care professionals. Less than 1 mile to 1 local hospital, 10 Miles from Allendale County, 24 Miles from Colleton Regional, 44 Miles from Beaufort Memorial. Accommodates comfortably 4 Guests - 4 BR, 2.5 BA, FULL HOUSE GENERATOR & Very CLEAN.

5.0 out of 5 average rating, 20 reviews
Top guest favorite
A wooden staircase descends towards a dock on serene waters, framed by tall grasses. A blue roofed structure is positioned at the water's edge, with boats visible nearby. The sky is partly cloudy, reflecting natural light onto the calm surface.
Home in Beaufort

Belle Monte (beautiful mountain) on the water!

Belle Monte is a lovely light-filled 2 story home on high bluff overlooking Middle Creek off the Whale Branch river in Beaufort, SC. See gorgeous sunrises & watch the dolphins from the upstairs deck or sun porch. Great views of the water from most of the house. New lighted dock on deep water so bring your boat! Enjoy swimming (ladder provided), kayaking or paddle boarding. Great area for fishing and crabbing. Well-equipped kitchen, fireplace, gas grill, screened-in porch, game table & more!

4.96 out of 5 average rating, 112 reviews
Superhost
The exterior of the house is framed by trees, featuring a wooden façade and a covered porch with a railing. The surrounding yard is grassy, providing a natural setting. A small staircase leads to the entrance, enhancing accessibility.
Home in Olar

The Pond House at Salkehatchie Farms

The Pond House is a secluded getaway in the woods with double glass doors throughout the house so you can enjoy nature, even while you are inside. It sits at the end of the winding drive through dogwoods in the spring, green trees in summer and colored leaves in autumn. There is a small pond on the edge of the property. Outdoor patios are a wonderful place to breathe in the early morning air, watch a sunset, or grill. There is plenty of room for walks and the property is yours to explore.

4.95 out of 5 average rating, 187 reviews
Top guest favorite
A well-appointed bedroom features a stylish metal bed frame with layered bedding and decorative pillows. Natural light filters through white blinds, illuminating the space. A bedside table with a lamp is positioned beside the bed, while a laundry basket and dresser are visible in the foreground.
Home in Walterboro

The Cozy Casa

Whether looking for a place to rest during your travels.. or staying in the area for a while, the Cozy Casa is the perfect choice! Stylish, clean, affordable, premium linens, very well stocked, 1.5 acre fully fenced yard, and located just a 2 minute drive off of Exit 53 of I- 95 in Walterboro, SC. Just a few minutes drive to everything! The Cozy Casa is a stand out Short Term Rental that truly takes hospitality seriously. Come and enjoy this very well appointed home.

5.0 out of 5 average rating, 229 reviews
Guest favorite
An aerial view showcases a spacious 4BR home set on 2 acres. Surrounding greenery includes trees and open lawn areas, with pathways leading to the main entrance. Adjacent structures and a gravel road are visible in the background, emphasizing the property’s serene setting.
Home in Yemassee

Lowcountry Orchard Getaway

Anderson Orchards – A Lowcountry Retreat Relax in this 4BR home on 2 acres with a bridge, oak tree, muscadine vines, pear, and pecan trees. Ideal for families or groups (sleeps 12+), it’s a peaceful retreat near top destinations: Beaufort – 40 min (historic downtown) Hilton Head – 1 hr (beaches, golf) Savannah – 1 hr (riverfront, nightlife) Charleston – 1 hr 15 min (historic charm) Parris Island – 45 min (boot camp grads) Plenty of space to relax and explore!

4.94 out of 5 average rating, 89 reviews
Top guest favorite
A softly lit Tiny House is nestled beneath a moss-draped tree, creating a serene ambiance at night. Reflections can be seen in the water nearby, enhancing the tranquil setting. The surrounding grass is lush and well-maintained, contributing to the peaceful rural environment.
Farm stay in Yemassee

“Tiny house” nestled on beautiful farm

We are less than 1 mile off of I-95 in the Low Country of South Carolina. Our 62 acre farm is nestled in the “middle of nowhere, but close to every where”. We are located close Beaufort, Charleston and Savannah! Our Tiny House, which used to be our feed shed, offers beautiful scenery from the Red barn, Moss draped Live Oak trees, Pecan Grove, horses, goats, free range donkeys and more. We have a brand new Bathhouse with a full bath. Washer & Dryer too!

4.96 out of 5 average rating, 132 reviews
Top guest favorite
Home in Furman

Superhost | Lowcountry Comfort | 3BR | 1GB Wi-Fi

Experience relaxed Southern comfort in this single-level 3BR/1.5BA Superhost home on a quiet 2.25-acre lot in Furman, SC, less than 1 minute (about 0.2 miles) from Town Hall and just off Hwy 601. Once home to Lizzie Young, Hampton County’s first female mayor and Furman’s first African American mayor (1990–1999), this historic stay blends local Black history, modern comfort, immaculate cleanliness, fast 1GB Wi-Fi, and peaceful surroundings guests love.

5.0 out of 5 average rating, 14 reviews
Guest favorite
An aerial view of the living area displays a warm wooden floor accompanied by two sofas and two armchairs arranged around a coffee table. Framed artwork adorns the walls, while natural light pours in through double glass doors leading to a wooden deck.
Home in Ridgeland

Low Country Serenity at Palm Key

This water-front house is located in the Palm Key community, a secluded 350-acre nature get-a-way on the Broad River about 10 minutes from I-95, 30 minutes from Beaufort and Parris Island, and 45 minutes to Hilton Head and Savannah, Georgia. Grocery stores and restaurants are located 15 minutes away in Ridgeland. If you like to cookout, we have a park style grill in the backyard. Relax in the shade of the Spanish moss covered live oak trees.

4.9 out of 5 average rating, 182 reviews
Superhost
Home in Colleton County

Country Living at Belle Estate

Escape to The Belle Estate — a spacious brick ranch home just minutes from I-95 and Walmart. This 3-bed, 2-bath home offers a large living room, dining room, bonus game room, spacious den, and brick courtyard. Conveniently located near restaurants, shopping, and local attractions. Whether you’re visiting for a weekend getaway, family gathering, or extended stay, The Belle Estate offers space, comfort, and convenience in a serene setting.

4.83 out of 5 average rating, 6 reviews
Top guest favorite
Cottage in Saint Helena Island

Private Waterfront Retreat w/ Sauna

Escape to The Hideaway, a newly built modern 2BR/2BA waterfront retreat on St. Helena Island. Surrounded by live oaks and sweeping salt marsh views, this architecturally unique cottage blends luxury and nature with curated amenities, including a private indoor sauna. Peaceful and secluded, yet just minutes from beaches, outdoor adventures, local shops, and dining—designed for rest, reconnection, and renewal.

4.98 out of 5 average rating, 146 reviews
Guest favorite
A spacious wooden deck is seen, surrounded by tall trees, providing a serene outdoor space. Two red chairs and a glass table are positioned on one side, while a wooden bench offers additional seating. Natural light filters through the greenery, enhancing the tranquil setting.
Cabin in Early Branch

"Tranquil Tiny Cabin Retreat"

"Experience the tranquility of our secluded tiny cabin in Early Branch, SC. Surrounded by nature, this charming retreat offers a peaceful escape. Relax by the fire pit, fish in the private pond, and enjoy the cozy interior with small rooms, bathroom, and kitchen. Ideal for those seeking serenity and intimacy in a rustic setting. Book now for a unique getaway unlike any other."

4.9 out of 5 average rating, 59 reviews
Guest favorite
A spacious bedroom features a four-poster bed topped with white and gray bedding. Two windows with light-filtering curtains provide natural light, while a dresser and a television are positioned in the room, creating a comfortable and functional space.
Home in Fairfax

Darlington’s corner

This home is nestled in a charming neighborhood directly off of highway, 278. Making it perfect for traveling construction and healthcare professionals. Within walking distance to Fairfax\Allendale hospital only 10 miles from Hampton regional medical center. Experience the charm of the South in this Idyllic retreat.

4.94 out of 5 average rating, 34 reviews

Popular amenities for Islandton vacation rentals