Guesthouse vacation rentals in Florida Panhandle
Find and book unique guesthouse rentals on Airbnb
Top-rated guesthouse rentals in Florida Panhandle
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Florida Panhandle guesthouse rentals
Family-friendly guest house rentals
Guesthouse in Panama City Beach
4.97 out of 5 average rating, 436 reviewsBella Cabana Vacation Rental House
Nov 2 – 9
Guesthouse in Fort Walton Beach
4.87 out of 5 average rating, 291 reviews➢ 30 Seconds to the Beach - Private Guest House! ☼
Nov 11 – 18
Guesthouse in Pensacola
4.91 out of 5 average rating, 599 reviewsCottage Under the Trees
Sep 2 – 9
Guesthouse in Apalachicola
4.91 out of 5 average rating, 103 reviewsDowntown Apalach /Blue Moon Loft
Nov 4 – 11
Guesthouse in Santa Rosa Beach
4.85 out of 5 average rating, 161 reviewsCarriage House 1.5 bed/1 bath located off 30A
Aug 5 – 12
Guesthouse in Pensacola
4.97 out of 5 average rating, 239 reviewsPet Friendly, Pool, Hot Tub, Fenced yard.
Dec 23 – 30
Guesthouse in Panama City
4.99 out of 5 average rating, 92 reviewsCabana Cottage @ St. Andrews-Waterfront/Pool/Dock
May 7 – 14
Guesthouse in Pensacola
4.74 out of 5 average rating, 148 reviewsPrivate Pool House
Jul 14 – 21
Guest house rentals with a patio
Guesthouse in Pensacola
4.93 out of 5 average rating, 138 reviewsCozy 1 bedroom East Hill Garage Apartment
Jan 14 – 21
Guesthouse in Panama City Beach
4.84 out of 5 average rating, 135 reviewsBeach Guest House Cottage by Pier Frank Brown 30a
Feb 12 – 19
Guesthouse in Pensacola
4.96 out of 5 average rating, 109 reviewsAdorable carriage house with private entrance
Feb 2 – 9
Guesthouse in Pensacola
4.93 out of 5 average rating, 159 reviewsBlue Skies Cottage travel oasis
Jan 5 – 12
Guesthouse in Pensacola
4.84 out of 5 average rating, 136 reviewsThe Carriageway Cottage -Close to Pensacola Beach!
Jun 16 – 23
Guesthouse in Panama City Beach
4.98 out of 5 average rating, 113 reviewsTiny Treasure Outdoor Oasis with Hot Tub
Jul 3 – 10
Guesthouse in Navarre
5.0 out of 5 average rating, 24 reviewsNever Navarre From Home Cottage
Jan 15 – 22
Guesthouse in Pensacola Beach
4.83 out of 5 average rating, 76 reviewsSonoran Mermaid’s Guest Suite
Jan 11 – 18
Guest house rentals with a washer and dryer
Guesthouse in Destin
4.98 out of 5 average rating, 337 reviewsCarriage House by the Beach
Oct 11 – 18
Guesthouse in Pensacola
4.97 out of 5 average rating, 596 reviewsNorth Hill Guesthouse
Oct 9 – 16
Guesthouse in Santa Rosa Beach
4.96 out of 5 average rating, 190 reviewsDune Villa - Santa Rosa Beach /30-A
Jun 4 – 11
Guesthouse in EastPoint
4.83 out of 5 average rating, 303 reviewsGone Coastal
Mar 1 – 8
Guesthouse in Gulf Shores
4.96 out of 5 average rating, 163 reviewsEscape relax & enjoy Lagoon Life
Dec 5 – 12
Guesthouse in Navarre
4.95 out of 5 average rating, 215 reviewsS.K.I. Beach House (Spending our Kids Inheritance)
Dec 25 – Jan 1
Guesthouse in Santa Rosa Beach
4.82 out of 5 average rating, 187 reviewsSanta Rosa Beach Tiny House
Nov 3 – 10
Guesthouse in Mobile
4.99 out of 5 average rating, 255 reviewsCharming Cottage - Historic Midtown
Jun 24 – Jul 1
Destinations to explore
- Panama City Beach Vacation rentals
- Orange Beach Vacation rentals
- Destin Vacation rentals
- Gulf Shores Vacation rentals
- Seaside Vacation rentals
- Alys Beach Vacation rentals
- Pensacola Beach Vacation rentals
- Pensacola Vacation rentals
- Panama City Vacation rentals
- Rosemary Beach Vacation rentals
- New Orleans Vacation rentals
- Atlanta Vacation rentals
- Guesthouse rentals United States
- House rentals United States
- Guesthouse rentals Florida
- House rentals Florida
- House rentals Panama City Beach
- House rentals Orange Beach
- House rentals Destin
- Villa rentals Florida Panhandle
- Rentals with lake access Florida Panhandle
- Beachfront rentals Florida Panhandle
- Waterfront rentals Florida Panhandle
- Rentals with a sauna Florida Panhandle
- Serviced apartment rentals Florida Panhandle
- House rentals Florida Panhandle
- Campsite rentals Florida Panhandle
- Rentals with a fireplace Florida Panhandle
- Bungalow rentals Florida Panhandle
- Condo rentals Florida Panhandle
- Apartment rentals Florida Panhandle
- Rentals with a kayak Florida Panhandle
- Rentals with an EV charger Florida Panhandle
- Resort rentals Florida Panhandle
- Hotel rentals Florida Panhandle
- Boutique hotel rentals Florida Panhandle
- Rentals with a hot tub Florida Panhandle
- Beach condo rentals Florida Panhandle
- Rentals with an accessible height bed Florida Panhandle
- Vacation home rentals Florida Panhandle
- Rentals with a patio Florida Panhandle
- Rentals with a washer and dryer Florida Panhandle
- Cabin rentals Florida Panhandle
- Townhouse rentals Florida Panhandle
- Monthly Rentals Florida Panhandle
- Beach house rentals Florida Panhandle
- Bed and breakfasts Florida Panhandle
- Smoking-friendly rentals Florida Panhandle
- Wheelchair accessible rentals Florida Panhandle
- Rentals with an accessible height toilet Florida Panhandle
- Private suite rentals Florida Panhandle
- Rentals with a home theater Florida Panhandle
- Cottage rentals Florida Panhandle
- Tiny house rentals Florida Panhandle
- Rentals with breakfast Florida Panhandle
- Rentals with outdoor seating Florida Panhandle
- Rentals with a fire pit Florida Panhandle
- Family-friendly rentals Florida Panhandle
- Fitness-friendly rentals Florida Panhandle
- Rentals with pools Florida Panhandle
- Pet-friendly rentals Florida Panhandle
- Rentals with beach access Florida Panhandle
- Kid-friendly rentals Florida Panhandle
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom