Vacation rentals in Edisto

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Edisto

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
Home in Orangeburg
4.94 out of 5 average rating, 72 reviews

Cozy, comfy, convenient, cottage!

We think you'll love this peaceful, family friendly cottage. For a price similar to a local hotel, you'll get a newly remodeled 2-bedroom house complete with kitchen and formal dining room located on fenced in lot 🐶 in quiet neighborhood. The master has a king bed with 400 count Egyptian cotton sheets and a bamboo mattress topper. The guest has a queen bed with a sensafoam mattress. There is a new 50” tv and high speed fiber WI-FI. There is also a breakfast bar with your favorite coffee.

Top guest favorite
The rustic cabin features weathered wooden siding and a metal roof partially covered by overhanging branches. A front porch with railings leads to a small entry door, surrounded by grass and shrubs. The serene natural setting complements the cabin's quaint charm.
Cabin in Rowesville
4.95 out of 5 average rating, 220 reviews

Mulberry Cabin, a rustic tiny house cabin

Mulberry Cabin is conveniently located halfway between Charleston and the capital city of Columbia in Rowesville, SC. Please note the cabin is located in a small town, not in the country. Rowesville is 11 minutes from the beautiful Edisto Memorial Gardens in Orangeburg. Orangeburg has many restaurants, Wal-Mart, and a Starbucks near I-26. Columbia is about an hour away. Charleston is about 75 minutes away. Enjoy a break from Wi-Fi as you watch a DVD and relax in a 130 year old rustic cabin.

Guest favorite
The exterior of a single-story, light-colored home is shown, featuring a sloped roof and front steps leading to a welcoming entryway. Lush greenery, including shrubs and trees, surrounds the house, creating a serene environment. A covered porch is visible, enhancing the outdoor space.
Apartment in Orangeburg
4.83 out of 5 average rating, 29 reviews

Cozy and Charming on Raysor

Cozy and comfortable fully furnished one bedroom on quiet street, fenced back yard and off street parking. Living room, Dining room, Office, Modern Kitchen, huge deck table, chairs. WiFi, Internet, TVs, Washer & Dryer. Pet Notes: Pets have to be approved in advance of stay and pet fees will be charged Pets are welcome but there is a pet fee based on number of dogs and breed. Airbnb only charged for 1 pet, we send request for additional pet fees. Some breed are restricted by insurance company.

Top guest favorite
A cottage resides beside a serene pond, surrounded by lush trees. Its inviting exterior features large windows reflecting on the water's surface. A wooden deck extends over the pond, providing access to nearby fishing and kayaking equipment, creating a peaceful natural setting.
Cottage in Lexington
5 out of 5 average rating, 178 reviews

Relax and unplug at this private oasis!

Our beautiful cottage for adults only is set on a private spring fed pond with all amenities to unwind from the day-to-day hustle. A porch with rocking chairs, brick fire pit and outdoor lighting in the courtyard make this your destination for relaxation. Take a walk in the 20 acres of wooded trails, fish, kayak, paddleboat, read a book, write, listen to music or just take a nap. This property lets you unplug from the world, relax, and connect with nature without giving up modern conveniences.

Top guest favorite
A spacious living area features a large blue sectional sofa adorned with patterned cushions. A light wooden coffee table sits on a soft area rug, complemented by a small potted plant. Natural light filters through the windows, creating a bright and welcoming environment.
Home in Orangeburg
5 out of 5 average rating, 148 reviews

The Grand Marshall

Bring the whole family to this renovated 3 BR, 2 bath home +1 BONUS ROOM, which serves as a theatre/game room with 2 queen sleeper sofas. Your family will enjoy: Coffee/beverage/snack bar Central location: Approximately 5 minutes to SC State and Claflin University, OC Tech College, Edisto Gardens, MUSC Health Orangeburg, shopping, dining, and more. Designated office space 1 king bed, 2 queen beds, plus 2 queen sleeper sofas 5 Roku Smart TV’s Smart lock for easy access High speed WiFi

Superhost
Cabin in Saint Matthews
4.77 out of 5 average rating, 197 reviews

A relaxing cabin on private pond. Old Bells Secret

Escape to our secluded cabin on 90 acres in St. Matthews, SC! This early 2000s style cabin features 2 cozy bedrooms, 1 bathroom, and a lovely porch. The large pond is perfect for swimming, fishing, or playing. It’s an endless adventure. The house can sleep up to 6 with the pull out couch. Accessible via a private road, it's perfect for weekend getaways with the family or housing for workers. Experience relaxation and adventure in nature at this wonderful cabin. Book now for a memorable stay!

Top guest favorite
Home in Orangeburg
5 out of 5 average rating, 19 reviews

Renovated—Spotless Home—Quiet Area Near Food/HBCUs

You’ll enjoy this spacious, modern farmhouse with waterfront view of a 5 acre pond. Located at the end of a cul de sac in a quiet area, this one-story, renovated home has lots of amenities — WiFi, A/C, full kitchen, desk, laundry room, whirlpool tub & more. Close to places of interest: — 2-3 minute drive • Dining, groceries, shopping • Orangeburg Recreational Park — 8-10 minute drive • South Carolina State University • Claflin University • Orangeburg Country Club • More dining options

Top guest favorite
A spacious living area features a warm wooden door, large windows allowing natural light, and a cozy seating nook with cushions. A flat-screen TV is mounted on the wall above a fireplace, while light-colored wood accents enhance the ambiance.
Treehouse in West Columbia
4.99 out of 5 average rating, 709 reviews

Luxury Treehouse in the heart of Columbia

Mid-Century Modern Treehouse with no stairs to climb but walk across a bridge thru beautiful professionally landscaped gardens onto a spacious deck with a hot tub. The view is over a bubbling creek set back into the woods. The barbecue grill and fire pit area complete with a twinkling chandelier and string lights. Relax inside and curl up and watch a movie in front of the fireplace! You have parking next to a walkway located between the treehouse and gardens next to our home.

Top guest favorite
A charming cottage is depicted with a welcoming front porch featuring a ceiling fan and comfortable seating. Lush greenery surrounds the entrance, while symmetrical stairs lead up to the porch area. Soft curtains gently frame the open space, inviting relaxation in the wooded setting.
Cottage in Hopkins
4.99 out of 5 average rating, 168 reviews

Charming Country Cottage Nestled in the Woods

Cedar Creek Cottage is conveniently located to everything Columbia & Sumter, SC has to offer, while nestled in a wooded setting for a peaceful stay. Newly renovated with lots to offer: comfy beds & linens, fully stocked kitchen, Wi-Fi, keyless entry, fire pit, back-up generator & 2 large porches. Master bedroom has a queen bed and private full-bath. Two additional bedrooms (1 queen, 1 full) with shared full-bath. Washer, dryer, iron, ironing board and steamer are available.

Top guest favorite
Tiny home in Batesburg-Leesville
4.98 out of 5 average rating, 111 reviews

Private 75 acre farm with lake

Quiet getaway at Lake Tom-A-Shawna Farm. Fully furnished 2 queen bed, 1 full bath, mini cabin that offers accommodations for traveling professionals, equestrians, and vacationers. This gated private property spans 75 acres, including a 20-acre lake, and features a 4-person cabin with full appliances, granite countertops, high-speed internet, 2 TVs, an electric fireplace, heat/AC, deck. Fishing, shooting, hiking or just relaxing. We offer fresh eggs and meat for purchase.

Top guest favorite
A spacious deck overlooks a serene cove, featuring a dining table surrounded by six chairs. Lounge seating is positioned nearby, inviting relaxation. Lush trees frame the area, with views of water and nearby boats visible, creating a calm retreat.
Home in Summerton
4.99 out of 5 average rating, 129 reviews

Cheerful 3 bedroom home on the lake

Great 3 bedroom home on the water. Perfect for family vacations, a weekend getaway or a stay for local fishing tournaments. This home is on a quiet cove that opens up to the larger lake. Get the best of both worlds. The cove is perfect for paddle boating, kayaking, fishing off the dock, grilling on the deck, or just relaxing on the screened porch enjoying the view. But, with the private dock you can bring your boats and jet skis to enjoy the entire lake.

Top guest favorite
An A-frame structure is pictured, elevated on a brick foundation. Sturdy wooden stairs lead to the entrance, flanked by a deck with railings. The surrounding area is filled with tall trees, and a car is parked underneath the apartment, offering a rustic country setting.
Apartment in Orangeburg
4.99 out of 5 average rating, 182 reviews

Elevated Country Apartment

Discover the charm of country-living in our cozy 1-bedroom elevated apartment, just a short drive from Orangeburg, Bamberg, and Neeses. Wake up to the sound of roosters crowing and enjoy your morning coffee with views of our picturesque homestead, or enjoy a glass of wine while watching the sun set below the majestic pines. Perfect for those seeking tranquility without sacrificing convenience, our apartment offers a fully-equipped kitchen and laundry.

Popular amenities for Edisto vacation rentals