House vacation rentals in East County, San Diego

Find and book unique houses on Airbnb

Top-rated house rentals in East County, San Diego

Guests agree: these houses are highly rated for location, cleanliness, and more.

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Guest favorite

Home in Borrego Springs

5.0 out of 5 average rating, 108 reviews

Charming Desert Getaway on Equestrian Property.

Get away to this peaceful desert ranch home in charming Borrego Springs California. Exceptionally clean two-bedroom, one bath, newly remodeled ranch home. Wi-Fi, large TVs in living area and master bedroom. YouTube TV subscribed. There is a Telescope to view our amazing views of the Milky Way. The house is completely furnished and equipped, it has everything you need to relax and enjoy your stay Beautiful princess horse on property, her name is Apache Tears and she loves carrots. No Pets Sorry

Jul 12 – 19

€ 153 per night

Guest favorite

Home in La Mesa

4.9 out of 5 average rating, 146 reviews

Classic Mid-Century Mount Helix Home with Views

Located in the exclusive Mount Helix neighborhood of La Mesa, this property is conveniently located near the 8 and 94 freeways for easy access to explore the greater San Diego area. Attractions like the historic Balboa Park with the San Diego Zoo or Sea World are a 15-25 minute drive away. With spacious interior and exterior spaces at the property, though you may find it difficult to leave. The property includes 4 bedrooms and 2.5 bathrooms with furnished living room, family room and kitchen.

Apr 17 – 24

€ 238 per night

Guest favorite

Home in Alpine

4.99 out of 5 average rating, 143 reviews

Fully Fenced Alpine Property with Guest House

Our guest house is located in the back of our personal property & kept private by fencing. Our property is fully fenced & guests have access in & out by using a keypad. We have laundry facilities, a queen size bed in the master bedroom, a sofa sleeper in the living room/kitchen area and a private patio with bbq. We occupy the main home on the property. We have 2 dogs on the property so other animals are not recommended at this location. Children play equipment is not included with Airbnb.

Sep 27 – Oct 4

€ 102 per night

Guest favorite

Home in Alpine, California, US

4.94 out of 5 average rating, 119 reviews

Cozy & Quiet Farmhouse - Family & Pet Friendly

Come relax at the newly remodeled Mariposa Farmhouse. Our goal is for you to smile and feel at home as soon as you enter. We are both pet & family friendly! Wake up with a cup of coffee from our complimentary coffee bar while enjoying beautiful mountain and high dessert views of the Cleveland National Forest from the master balcony. At night, relax by the fire under the stars. We are minutes to the 8 FWY & Viejas Casino, & 30 Minutes to either San Diego, beaches, attractions and Julian.

Mar 13 – 20

€ 207 per night

Guest favorite

Home in La Mesa

4.85 out of 5 average rating, 177 reviews

Newer "Manor Studio"

Centrally located in San Diego County this brand new studio style unit has a private entrance, private patio area and street parking. Furnished with a queen size bed, love seat, full bathroom and kitchen area. One large drawer to accommodate personal items, and a wall rack to hang clothing. There is a smart TV with WiFi streaming capabilities and lots of USB plugs to charge your devices. On street parking in front of unit (no parking in driveway). No Pets allowed. No Hair Dying allowed.

Jul 25 – Aug 1

€ 148 per night

Guest favorite

Home in Ramona

4.98 out of 5 average rating, 730 reviews

The Glass House - A Nature Retreat

Enjoy a unique retreat; 180 degrees of views from inside the home. Nestled at the end of a private road, our place is nearby great hiking and countryside wineries. The Glass House provides a magical space and nature retreat where individuals, couples, families and friends can gather together to re-connect with nature, each other, and themselves. The breathtaking mountain top views, the huge deck, hot tub, fireplace, and the open concept living space is unbeatable for the perfect getaway.

Aug 23 – 30

€ 366 per night

Guest favorite

Home in La Mesa

4.93 out of 5 average rating, 179 reviews

Cottage in the Garden! New! Modern!

COTTAGE IN THE GARDEN - New! Modern! Find beauty and serenity in this special guest house in one of San Diego's most desirable areas! Flowering bushes, plants, olive tree and fruit trees seen from all windows. All amenities: WiFi, Cable, serving dishes and tableware, full coffee bar, Ninja Blender, Flat screen TVs, 100% Egyptian Cotton Sheets or Boll and Branch Sheets (used by 3 Presidents), Japanese Toilette and more. 15 minutes to Downtown San Diego and 20 minutes to the beach!

Apr 11 – 18

€ 155 per night

Guest favorite

Home in Julian

4.95 out of 5 average rating, 109 reviews

*BRAND NEW* Mountain Getaway w/ Hot Tub

This newly renovated 1 bed/1 bath home in Julian, CA offers the perfect escape from city life. Situated just minutes away from the heart of Julian, guests can enjoy breathtaking views and stunning natural landscapes. The cozy interior features a comfortable living room, fully equipped kitchen, several workspaces and a spacious bedroom with a plush king-sized bed. There is also a private hot tub and outdoor deck, perfect for watching the stars at night or enjoying your morning coffee!

Sep 16 – 23

€ 207 per night

Guest favorite

Home in San Diego

4.89 out of 5 average rating, 366 reviews

Ocean Beach Close to all

*We are Covid-19 aware! We have taken extra precautions--sanitizing all surfaces possible, including remote controls, door handles, light switches, etc... after each visit! And we open all the windows to aerate before the next guests! One bedroom granny flat, separate entrance with off street parking for midsize car or smaller. Three blocks to the beach. Located at the edge of downtown OB close to all restaurants and night life. Centrally located to all main San Diego attractions.

Mar 25 – Apr 1

€ 124 per night

Superhost

Home in San Diego

4.81 out of 5 average rating, 141 reviews

PRIVATE CASITA: BEACH, DOWNTOWN, ZOO W/IN 15 MIN!

SEND US A MESSAGE FOR SPECIAL OFFER! Book Now For A Memorable Experience with your partner! Kick back and relax in a safe, stylish, and quiet studio. Check in contactless and enjoy! Cozy, comfy, and a perfect base for exploring the city. Cook your own meal in the kitchenette and enjoy your meal at the cute dining area outside for any child or infant to play. The entire guest house is is 5 minutes from SDSU, 15 minutes from the beach and 15 minutes from downtown San Diego.

Feb 16 – 23

€ 132 per night

Guest favorite

Home in Ramona

4.97 out of 5 average rating, 306 reviews

Wine Country Retreat - Tranquility Hottub/Views

Take the back roads scenic drive 50mins up the hill from San Diego and enjoy some much needed quiet and comfy tranquility. Our place is right in the heart of San Diego Wine Country. It's a rather well appointed place situated on 10 private acres that overlooks expansive green space. With only few neighbors in any direction, you can either sleep with the windows open and wake early to roosters crowing, or close the windows and sleep quietly til Noon.

May 18 – 23

€ 232 per night

Guest favorite

Home in El Cajon

4.95 out of 5 average rating, 309 reviews

Private Vineyard Estate w/ Guest House & Hot Tub

Enjoy a quiet oasis where family and friends can relax and play within the privacy of a gated 2-acre vineyard with endless on-site activities. The home layout is ideal for families or friends, with 4 bedrooms in the main house and the convenience and privacy of a separate Guest House (included in rental) with a full kitchen, living room, bathroom and bedroom. **Please no extra guests, events or gatherings**

Oct 22 – 29

€ 515 per night