
House vacation rentals in Downtown
Find and book unique houses on Airbnb
Top-rated house rentals in Downtown
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Downtown house rentals
House rentals with a pool

3 BR Urban Oasis with Pool and Spa in Great Area

The Queen House

La Jolla Beach House-Family Focused-3min to Beach

Your Modern Lux Pool Resort in the Heart of SD

Luxurious North Park Home - Walk to Dining & Shops

Lionhead - Private Boutique Home

University Heights Oasis Getaway

Designer Luxury Rental With Pool
Weekly house rentals

Ocean View in the Heart of Ocean Beach/Point Loma

2. Amazing Comfort Family Reunion J street

Walkable North Park Urban Oasis with Private Yard

Charming 1 bd Cottage Close to All

Charming Spanish Mission Home

Private home & yard-mins to Zoo DT Balboa Beach NP

Snazzy Spot with yard near beaches and downtown

Upscale Oasis, Downtown SD, BBQ, Fire Pit & More!
Private house rentals

Designer Park-Side: Minutes to Zoo & Down Town

Bright & Modern OB Getaway

Shadow House Mt. Helix

Freshly Remodeled Granny Flat - Close to it all!

Stylish Suite Near Downtown & Convention Center

Little Italy Historical

Golden Gem 2 - Cozy 1 Bed, Downtown Views & Patio

On The Beach Casita - Bay front access
Quick stats about house rentals in Downtown
Total rentals
160 properties
Nightly prices starting at
€ 52 before taxes and fees
Total number of reviews
12K reviews
Family-friendly rentals
110 properties are a good fit for families
Pet-friendly rentals
40 properties allow pets
Rentals with dedicated workspaces
90 properties have a dedicated workspace
Destinations to explore
- Fitness-friendly rentals Downtown San Diego
- Townhouse rentals Downtown San Diego
- Rentals with beach access Downtown San Diego
- Rentals with a fireplace Downtown San Diego
- Waterfront rentals Downtown San Diego
- Apartment rentals Downtown San Diego
- Loft rentals Downtown San Diego
- Rentals with a beach view Downtown San Diego
- Rentals with a washer and dryer Downtown San Diego
- Family-friendly rentals Downtown San Diego
- Rentals with a sauna Downtown San Diego
- Rentals with a fire pit Downtown San Diego
- Rentals with pools Downtown San Diego
- Rentals with outdoor seating Downtown San Diego
- Pet-friendly rentals Downtown San Diego
- Rentals with an EV charger Downtown San Diego
- Rentals with a home theater Downtown San Diego
- Rentals with a hot tub Downtown San Diego
- Smoking-friendly rentals Downtown San Diego
- Hotel rentals Downtown San Diego
- Rentals with breakfast Downtown San Diego
- Serviced apartment rentals Downtown San Diego
- Condo rentals Downtown San Diego
- Rentals with a patio Downtown San Diego
- House rentals San Diego
- House rentals San Diego County
- House rentals California
- House rentals United States
- Rosarito Beach
- Oceanside City Beach
- Torrey Pines State Beach
- Pacific Beach
- Tijuana Beach
- Coronado Beach
- SeaWorld San Diego
- LEGOLAND California
- University of California San Diego
- San Diego Zoo Safari Park
- Balboa Park
- La MisiĂłn Beach
- Oceanside Harbor
- Coronado Shores Beach
- Black's Beach
- Belmont Park
- Sesame Place San Diego
- Moonlight Beach
- Liberty Station
- Law Street Beach
- USS Midway Museum
- Torrey Pines Golf Course
- Mission Beach
- Santa Monica Beach