
Family-friendly vacation rentals in Downtown
Find and book unique family-friendly homes on Airbnb
Top-rated family-friendly rentals in Downtown
Guests agree: these family-friendly homes are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Downtown family-friendly rentals
Family-friendly home rentals with a hot tub

Lovely Guesthouse in garden setting

Mountain View Retreat in Gated Estate (Hot Tub)

Urban Retreat

University Heights Oasis Getaway

Nature Escape •Sauna•SoakTub•Views+Zoo pkg add-on

Luxury Oceanfront Condo with Unbelievable Views

Ultimate Getaway: Spa, Game Rooms, Firepit, Views

Beautiful Historic Home and Gardens Near Downtown!
Family- and pet-friendly home rentals

Insta-worthy! 1 night/many nights, no min required

Little Italy 2BR Loft Near Waterfront & Convention

Awesome Skyline View

Stylish/Modern/Gaslamp/Spacious 1BR/1BA

Luxury Bay/Ocean view suite-San Diego/Mission Bay

NEW Stylish❤️ of Downtown Little Italy w Parking/AC

Modern Bankers Hill Studio on Maple Canyon

Modern 2BR Townhome w/Free Parking. Walk to Petco
Family-friendly home rentals with a pool

Hillcrest canyon home casita with pool access

Your Modern Lux Pool Resort in the Heart of SD

The BEST NEST Clean, peaceful, private, affordable

Private 1 BR Paradise retreat

Private Poolside Cabana

The Tiny Helix

Designer Luxury Rental With Pool

Custom Guesthouse, Balboa Park/Zoo/Hillcrest& pool
Quick stats about vacation rentals that are family-friendly in Downtown
Total rentals
740 properties
Nightly prices starting at
€ 43 before taxes and fees
Total number of reviews
28K reviews
Pet-friendly rentals
230 properties allow pets
Rentals with a pool
240 properties have a pool
Rentals with dedicated workspaces
490 properties have a dedicated workspace
Destinations to explore
- Rentals with outdoor seating Downtown San Diego
- Boutique hotel rentals Downtown San Diego
- Condo rentals Downtown San Diego
- Smoking-friendly rentals Downtown San Diego
- Rentals with breakfast Downtown San Diego
- House rentals Downtown San Diego
- Rentals with beach access Downtown San Diego
- Rentals with a home theater Downtown San Diego
- Hotel rentals Downtown San Diego
- Apartment rentals Downtown San Diego
- Loft rentals Downtown San Diego
- Hostel rentals Downtown San Diego
- Rentals with a hot tub Downtown San Diego
- Rentals with an EV charger Downtown San Diego
- Rentals with a beach view Downtown San Diego
- Rentals with a washer and dryer Downtown San Diego
- Rentals with a fire pit Downtown San Diego
- Pet-friendly rentals Downtown San Diego
- Rentals with pools Downtown San Diego
- Waterfront rentals Downtown San Diego
- Rentals with a fireplace Downtown San Diego
- Serviced apartment rentals Downtown San Diego
- Rentals with a patio Downtown San Diego
- Fitness-friendly rentals Downtown San Diego
- Townhouse rentals Downtown San Diego
- Rentals with a sauna Downtown San Diego
- Family-friendly rentals San Diego
- Family-friendly rentals San Diego County
- Family-friendly rentals California
- Family-friendly rentals United States
- Rosarito Beach
- Oceanside City Beach
- Torrey Pines State Beach
- Tijuana Beach
- Pacific Beach
- SeaWorld San Diego
- University of California San Diego
- LEGOLAND California
- Coronado Beach
- San Diego Zoo Safari Park
- Balboa Park
- La Misión Beach
- Oceanside Harbor
- Coronado Shores Beach
- Belmont Park
- Liberty Station
- Black's Beach
- Moonlight Beach
- Sesame Place San Diego
- Law Street Beach
- Torrey Pines Golf Course
- Mission Beach
- Santa Monica Beach
- USS Midway Museum