Guesthouse vacation rentals in Central Florida
Find and book unique guesthouse rentals on Airbnb
Top-rated guesthouse rentals in Central Florida
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Central Florida guesthouse rentals
Family-friendly guest house rentals
Guesthouse in Orlando
4.93 out of 5 average rating, 162 reviewsPrivate Backyard Cottage in Mills50
Oct 20 – 27
Guesthouse in Lakeland
4.98 out of 5 average rating, 214 reviewsModern lakeside retreat by SEU and FSC
Jul 31 – Aug 7
Guesthouse in Windermere
4.94 out of 5 average rating, 240 reviewsSmall Guesthouse near Orlando's Theme Parks
Jun 25 – Jul 2
Guesthouse in Fort McCoy
4.88 out of 5 average rating, 258 reviewsBlueberry Farm Country Cottage
Nov 18 – 25
Guesthouse in Winter Park
4.82 out of 5 average rating, 234 reviewsWELCOME HOME IN WINTER PARK
Apr 12 – 19
Guesthouse in Ocala
4.96 out of 5 average rating, 160 reviewsCozy cottage on private Ocala ranch
Aug 21 – 28
Guesthouse in Merritt Island
5.0 out of 5 average rating, 106 reviewsIsland Cottage
Jul 2 – 9
Guesthouse in Tampa
4.84 out of 5 average rating, 897 reviewsCharming private guest house.
Sep 30 – Oct 7
Guest house rentals with a patio
Guesthouse in Cocoa Beach
4.98 out of 5 average rating, 204 reviewsThe Cocoa Boho Rooftop Retreat
Mar 22 – 29
Guesthouse in Orlando
4.95 out of 5 average rating, 133 reviewsJefferson St. Cottage
Oct 21 – 28
Guesthouse in Orlando
4.96 out of 5 average rating, 186 reviewsCharming 1 bedroom Casita with private entrance
Aug 20 – 27
Guesthouse in Maitland
4.98 out of 5 average rating, 118 reviewsPrivate 1-bd Mid-Century Guesthouse
Sep 4 – 11
Guesthouse in New Port Richey
5.0 out of 5 average rating, 104 reviewsPalm Hideaway on the Cotee River
Apr 28 – May 5
Guesthouse in Mount Dora
4.93 out of 5 average rating, 136 reviewsEnjoy downtown: modern studio w/ kitchenette
Jun 23 – 28
Guesthouse in Tampa
4.97 out of 5 average rating, 263 reviewsContainer Home with Hot Tub & Magical Backyard
Jul 19 – 26
Guesthouse in Sebastian
4.93 out of 5 average rating, 114 reviewsQuiet cottage on Sebastian River property
Jun 20 – 27
Guest house rentals with a washer and dryer
Guesthouse in Orlando
4.96 out of 5 average rating, 490 reviewsPrivate Luxurious Apt. - Historic Downtown Orlando
Oct 9 – 16
Guesthouse in Sanford
4.95 out of 5 average rating, 227 reviewsPalmetto Pool Retreat
Nov 20 – 27
Guesthouse in Orlando
4.97 out of 5 average rating, 289 reviewsOasis Garden Cottage -cozy, chic, near everything!
Aug 27 – Sep 3
Guesthouse in Mount Dora
4.97 out of 5 average rating, 170 reviewsThe Carriage House - Walk to Downtown!!!!
Jun 9 – 16
Guesthouse in Tampa
4.97 out of 5 average rating, 214 reviewsTreetop Oasis
Sep 5 – 12
Guesthouse in Orlando
4.98 out of 5 average rating, 351 reviewsLakefront Seclusion modern guesthouse+Pool+Hot tub
Sep 14 – 21
Guesthouse in Orlando
4.9 out of 5 average rating, 383 reviewsBungalow Close to Attractions and Downtown Orlando
Mar 18 – 25
Guesthouse in DeLand
4.99 out of 5 average rating, 143 reviewsNo Worries Carriage House, 5 min walk to Stetson
Jul 23 – 30
Destinations to explore
- Kissimmee Vacation rentals
- Tampa Vacation rentals
- Orlando Vacation rentals
- Sarasota Vacation rentals
- Anna Maria Island Vacation rentals
- Naples Vacation rentals
- West Palm Beach Vacation rentals
- Boca Raton Vacation rentals
- Fort Lauderdale Vacation rentals
- Miami Vacation rentals
- Miami Beach Vacation rentals
- Key West Vacation rentals
- Guesthouse rentals United States
- House rentals United States
- Guesthouse rentals Orlando
- House rentals Orlando
- Guesthouse rentals Florida
- House rentals Florida
- Guesthouse rentals Florida
- House rentals Florida
- Guesthouse rentals Kissimmee
- House rentals Kissimmee
- Rentals with pools Central Florida
- Cabin rentals Central Florida
- Rentals with an accessible height toilet Central Florida
- Rentals with a sauna Central Florida
- Rentals with outdoor seating Central Florida
- Boutique hotel rentals Central Florida
- Rentals with a home theater Central Florida
- Aparthotel rentals Central Florida
- Rentals with lake access Central Florida
- Tiny house rentals Central Florida
- Resort rentals Central Florida
- Pet-friendly rentals Central Florida
- Luxury rentals Central Florida
- Smoking-friendly rentals Central Florida
- RV rentals Central Florida
- Private suite rentals Central Florida
- Rentals with a washer and dryer Central Florida
- Serviced apartment rentals Central Florida
- Family-friendly rentals Central Florida
- Beachfront rentals Central Florida
- House rentals Central Florida
- Wheelchair accessible rentals Central Florida
- Barn rentals Central Florida
- Apartment rentals Central Florida
- Rentals with beach access Central Florida
- Rentals with an accessible height bed Central Florida
- Houseboat rentals Central Florida
- Cottage rentals Central Florida
- Rentals with breakfast Central Florida
- Bed and breakfasts Central Florida
- Monthly Rentals Central Florida
- Farmstay rentals Central Florida
- Rentals with a fire pit Central Florida
- Rentals with a kayak Central Florida
- Rentals with an EV charger Central Florida
- Fitness-friendly rentals Central Florida
- Townhouse rentals Central Florida
- Kid-friendly rentals Central Florida
- Rentals with a fireplace Central Florida
- Ski-in/ski-out rentals Central Florida
- Bungalow rentals Central Florida
- Rentals with a patio Central Florida
- Loft rentals Central Florida
- Boat rentals Central Florida
- Hotel rentals Central Florida
- Villa rentals Central Florida
- Campsite rentals Central Florida
- Condo rentals Central Florida
- Vacation home rentals Central Florida
- Waterfront rentals Central Florida
- Rentals with a hot tub Central Florida
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom