Vacation rentals in Carlisle

A Taste of Southern Comfort!

Here is a taste of Southern Comfort in the little quite town of Carlisle, S.C. Located 15 minutes from Union; 30 minutes from Newberry; 2BR/3BA, 2 Master Bathrooms (1 King Size Bed and 1 Queen Size Bed). Direct TV and WIFI. Keycode lock entry. Built in 1917, on 2 acres. Fully stock kitchen, 2 refrigerators, mudroom, workstation, patio deck, washer and dryer, fire pit, tree swing, gas and charcoal grills w/utensils, games. NO CATS. Some dogs are allowed per request. Sorry-No Hunters Camp.

#1 most loved AirBnB in SC! *Old Soul Treehouse*

The Old Soul Treehouse is a fabulous destination for couples looking to have a unique getaway! This is a waterfront treehouse on Lake Greenwood with a private dock, heat/AC, hot tub, king size bed, & a fully equipped kitchen & bathroom. Take a dip in the lake during the day or at night enjoy a soak in the hot tub on the peaceful porch under the stars. Book with us and you will soon be enjoying luxury by the water during this intimate experience with the one you love. We would love to have you!

Luxury Retreat & Heated Pool Downtown Simpsonville

Luxury Pool House in the Heart of Simpsonville – Perfect for Gatherings! Designed for comfort, fun, and relaxation. 2 minutes from Downtown Simpsonville and 15 minutes from Downtown Greenville, this luxury retreat feels like a private resort with all the warmth of home. With nature views and countless amenities, you’ll have everything you need for an unforgettable stay. Up to 8 guests with 4 Spacious Beds and 2.5 Baths. Indoor & Outdoor Entertainment, Well-Equipped Kitchen, Cozy Living Room!

The Inspiration House

Ryan and I are certain you will love Newberry's friendly "small town" atmosphere. Our home was built in the late 1800's. It provides visitors with an eclectic blend of "old house" charm and modern updates within walking distance to the Newberry Opera House and wonderful downtown restaurants. The house features over 3,600 square feet of high ceilings, heavy pocket doors for privacy, three fireplaces, four bedrooms with three queen and two twin beds, 3.5 baths..and a wonderful front porch.

Farm Getaway

Come and experience the beauty of life on a farm! This beautiful space has its own private exterior entrance off of the picturesque wrap around farmhouse porch and is complete with all the classic and simple farmhouse touches. We are a working livestock farm raising cows, sheep, chicken, ducks, pigs & more. This space is perfect for some outdoor adventure time while still being close to historic downtown Newberry, home of the Newberry Opera House, & not far from Greenville and Columbia.

Sunset Cove-Beautiful Lake views

Your home away from home on Lake Murray! Spacious, modern clean, home with 3 levels of living -3 spacious decks, screen porch, and sunroom all with massive lake views! Plenty to do at Sunset Cove relaxing with family and friends and toys galore! "Wow just wow, best Airbnb ever..Sarah, June 2026. "..clean, beautiful view and so many fun games..Lisa, Oct 2025."Perfect setting for a quiet getaway. The house was amazing, clean, and had all the amenities we were looking for.."Jay, Sept 2025

Completely Furnished CLEAN Comfortable Quiet Home

If you are looking for a very clean and comfortable stay just a few minutes from downtown Newberry and very close to interstate 26, this is the place. It is on a safe dead end road. It’s in a country setting just off Highway 176 and an easy drive to the Sumter National Park, Palmetto Trails and the Jenkinsville VC Summer plant. We take great pride in providing a place to relax while visiting Newberry and surrounding areas. ALL dogs MUST be approved before booking . Thank you

The Gem of Newberry | Sleeps 6

Welcome to our Airbnb located in Newberry, South Carolina! Located just a few minutes away from downtown Newberry and Newberry College, this Airbnb is conveniently located to some of the city's best dining, shopping, and entertainment options. The property is also just a short drive away from Lake Murray, one of South Carolina's most popular recreational destinations. Come and experience the best of modern living in this beautiful Airbnb in Newberry, South Carolina!

Marcy's Place

Take it easy at this unique and tranquil getaway surrounded by acres of wooded land and privacy. This Tiny House with porch was constructed of Logs in 2022. The outside logs are painted gray to blend in with nature. The inside is beautiful natural pine, with 3 bedrooms/1 bath/2 queen and 2 bunk beds with a loft, washer/dryer. It's conveniently located 4 miles off Interstate I 77 and 2 miles from the 1770 Historical town of Ridgeway, SC off Hwy 21 north.

Cozy 3-bedroom home near Presbyterian College

Our home sits on one acre of land. It is a calm & tranquil place to relax and unwind. Property is located just over 1 mile from Presbyterian College and even closer to downtown Clinton. Property is 40 minutes from Greenville. Property sleeps 6 with one queen bed in the Master Bedroom. Property has Smart TVs throughout, Propane Grill, WiFi, Laptop-friendly workspace , Washer & Dryer. Reach out with any questions or to check availability

Historic Log cabin on private fishing lake

Magnificent historic Log Cabin located on the shores of a private 10 acre lake surrounded by over hundreds of acres of forested isolation. One mile into the woods and away from the stress, hustle and bustle of everyday life. Access to 100 acre parcel for walking trails, fishing, canoeing, swimming, campfire and wildlife. Great opportunity to unplug from the stress and engage with family and friends! A great spot for an artist retreat!

The Westwood Backyard - Retreat or remote working

Kick back and relax at The Westwood Backyard in Chapin SC! This new charming and cozy 3 Bedroom, 2 bathroom home adjacent to a new neighborhood with a wooded backyard is modern and well decorated. It is an ideal home for family vacation. Lake Murray, Timberlake country club, and Dreher Island State park are nearby. Restaurants, grocery stores, and local night spots, are close by. Columbiana mall is 20 min and Columbia is 25 min away!