
Vacation rentals in Brandywine Creek
Find and book unique accommodations on Airbnb
Top-rated vacation rentals in Brandywine Creek
Guests agree: these stays are highly rated for location, cleanliness, and more.

Lukie’s Perfect Lil Getaway • Hot Tub & Fire Pit *
Welcome to your cozy Wilmington escape, perfect for relaxing, reconnecting, and unwinding in style. This charming 3-bedroom home blends comfort and character, featuring hardwood floors, large sun-filled windows, and a warm gas fireplace that creates the perfect space to relax. Enjoy slow mornings on the inviting front porch, or sip coffee in the bright sunroom just off the kitchen. Step outside to your private backyard oasis, where a hot tub and fire pit are ready for evenings under the stars
4.77 out of 5 average rating, 103 reviews
Downtown Luxury | Free Parking | Steps to DuPont
Experience the perfect blend of historic character and modern luxury in this beautifully renovated townhouse steps from Rodney Square. Whether visiting for business, events or a retreat, this centrally located home is within walking distance of Wilmington’s top dining, nightlife and the iconic Hotel DuPont. • Plush, hotel-quality bedding for restful sleep • High-speed Wi-Fi ideal for remote work and streaming • Roku Smart TVs • Private off-street parking — a rare downtown amenity Book today!
4.88 out of 5 average rating, 166 reviews
Radiant 4-Bed Haven w/ King suite in N. Wilmington
Discover a stunning 4-bedroom haven, recently updated & ideal for all abilities. ✓ Enjoy secure parking, high-speed wifi, and a delightful coffee & tea bar. ✓ Indulge in Disney & Netflix, tax-free shopping, and unwind in the Jacuzzi tub. ✓ Benefit from a washer & dryer in-unit for added convenience. ✓ Perfectly situated for Northeast travel with easy access to I-95, parks, attractions, cafes, and eateries. ✓Your pets are welcome too! Book now for a memorable and inclusive getaway!
4.72 out of 5 average rating, 309 reviews
Elegant Spacious Retreat | Perfect for Families
Relax and unwind in this charming 4-bedroom, 2-bath brick detached home, perfect for families, groups, or anyone looking for a peaceful retreat with a contemporary charm. Step inside and feel right at home in the spacious living area, complete with a wood-burning stove—the perfect spot to curl up with a book or enjoy a cozy evening by the fire. Prepare your favorite meals in the fully equipped kitchen and enjoy a good night's rest in each of the spacious and luxurious bedrooms.
5.0 out of 5 average rating, 23 reviews
Cozy 2-BR Retreat Private Parking Near Downtown
Welcome to our charming 2-bedroom 1 Bathroom retreat nestled in the heart of the historic District in Wilmington, our home is the perfect blend of historic charm and modern comfort. Conveniently located near I-95 and I-495, and just minutes from Wilmington Riverfront and its downtown attractions, less than 30 minutes to Philadelphia International Airport. Offering a perfect blend of comfort and convenience, for those wishing to explore the rich heritage and vibrant culture.
4.95 out of 5 average rating, 60 reviews
Charming Cottage Retreat in N. Wilmington Near I95
Welcome to our cozy cottage-style home in North Wilmington! Perfect for families, business travelers, or weekend getaways, this charming stay features 2 bedrooms, 2 full baths, a finished basement sleeping area, and comfortable space for groups. Enjoy nearby parks, restaurants, and quick access to Wilmington and Philadelphia. Relax in a quiet neighborhood and enjoy the surrounding nature while still being close to everything you need for a comfortable stay.
4.96 out of 5 average rating, 28 reviews
5BR Home Sleeps 10+Perfect for Groups+Skyline View
Spacious 5BR Home – Sleeps 10+ | Perfect for Groups Enjoy the entire home—offering comfort, space, and classic character for your stay. This 5-bedroom home sleeps 10 and is ideal for families, teams, or work travel. Plenty of space to gather and relax. ✔ 5 Bedrooms | Sleeps 10+ ✔ 2 Updated Full Bathrooms ✔ Living, Dining & Full Kitchen ✔ Office + Library Space Private backyard and three porches to unwind. 📍 24 minutes to Philadelphia No pets. No parties.
4.83 out of 5 average rating, 47 reviews
Cozy Townhome w/ Private Parking
Enjoy this comfy townhome centrally located near I-95 and I-495. It is also 10 minutes to the Wilmington Riverfront and downtown attractions; less than 30 minutes to Philadelphia International Airport and Philadelphia Center City. This home has two spacious bedrooms- one which contains a queen bed and the other with two XL twin beds (that can be converted into a king bed upon request). The basement and one bedroom closet will not be accessible.
4.9 out of 5 average rating, 109 reviews
Unbelievably Charming Tiny Home
Completely private stand alone tiny house, comfortable for 1-4 people. Guaranteed the absolute coziest place to stay in Trolley Square. Unusual amenities include: - Loaded pantry and fridge - Yoga mats & blocks - King size lofted bed Downtown Trolley and Brandywine Park are less than a minute walk. Right next to restaurants, Acme, several coffee shops, bus stop, and bars. Close to many attractions including Longwood Gardens and Winterthur.
4.95 out of 5 average rating, 435 reviews
The Lighthouse
Centrally located in northern Delaware with easy on/off access to 95 and 495. Newer construction, built in 2018. One large bedroom with KING size bed, 1.5 bath, private entrance, living room and full eat in kitchen. Work station area. Twin size pull out in living room. Free WiFi and large smart TVs in living room and bedroom. Deck off of the kitchen and upstairs deck off of the bedroom. Laundry located in bedroom upstairs. NO CLEANING FEE
4.98 out of 5 average rating, 127 reviews
The Loft at Trenton Place | Stylish City Stay
Welcome to The Loft at Trenton Place, a stylish urban retreat with an elevated edge. This newly renovated loft blends modern luxury with original character, featuring soaring ceilings, striking interiors, a sleek kitchen with waterfall island, and an open, airy layout. Tucked into Wilmington’s Trinity Vicinity, you’re minutes from downtown, the Riverfront, Amtrak and I-95 and is perfect for couples, professionals and weekend escapes.
5.0 out of 5 average rating, 4 reviews
Spacious 4-bedroom oasis
Forget your worries in this spacious and serene space. The 4 bedroom 2.5 bath home features ample space to spread out and is perfectly suited for long-term guests. All the bedrooms have at a minimum queen size beds, TVs in every room, and working desks and chairs. All the rooms also have wired and wireless internet at gigabit speeds. There is a full kitchen, washer, and dryer on the premises. Come enjoy your home away from home.
4.9 out of 5 average rating, 51 reviewsPopular amenities for Brandywine Creek vacation rentals
Other great vacation rentals in Brandywine Creek

Peaceful City Retreat | 2BR w/ Vintage Charm
4.89 out of 5 average rating, 72 reviews
Modern 2-bed downtown Wilmington
4.73 out of 5 average rating, 41 reviews
Perfect Getaway | Close to Philly & Wilmington!
4.75 out of 5 average rating, 28 reviews
Delaware City Oasis|Indoor Heated Pool
4.87 out of 5 average rating, 71 reviews
Extended Stay 1BR + Free Parking + Near Hospital
4.83 out of 5 average rating, 141 reviews
One Bedroom Wilmington Riverfront Apartment
4.95 out of 5 average rating, 20 reviews
Charming townhouse in historic Wilmington
4.98 out of 5 average rating, 85 reviews
Exquisite Loft Dwtn with free parking and No Fees!
4.81 out of 5 average rating, 68 reviewsDestinations to explore
- New York Vacation rentals
- Philadelphia Vacation rentals
- Washington Vacation rentals
- Boston Vacation rentals
- Ocean City Vacation rentals
- Pittsburgh Vacation rentals
- Virginia Beach Vacation rentals
- Niagara Falls Vacation rentals
- Jersey City Vacation rentals
- Newark Vacation rentals
- Baltimore Vacation rentals
- Richmond Vacation rentals
- Sesame Place
- Pennsylvania Convention Center
- Longwood Gardens
- Wells Fargo Center
- University of Pennsylvania
- Citizens Bank Park
- Fairmount Park
- Philadelphia Museum of Art
- Dutch Wonderland
- Temple University
- Betterton Beach
- Dover Motor Speedway
- Amish Village
- University of Delaware
- Drexel University
- French Creek State Park
- Diggerland
- Lincoln Financial Field
- Philadelphia Zoo
- Marsh Creek State Park
- 30th Street Station
- Greater Philadelphia Expo Center & Fairgrounds
- Independence Hall
- Valley Forge National Historical Park





