Guesthouse vacation rentals in Anderson County
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Top-rated guesthouse rentals in Anderson County
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
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Popular amenities for Anderson County guesthouse rentals
Family-friendly guest house rentals
Guesthouse in Pelzer
4.97 out of 5 average rating, 111 reviewsSouth Oaks Guesthouse
Sep 13 – 20
Guesthouse in Pendleton
4.9 out of 5 average rating, 240 reviewsLa Bella Farm
Feb 22 – Mar 1
Guesthouse in Donalds
4.99 out of 5 average rating, 344 reviewsHome on the farm
Mar 28 – Apr 4
Guesthouse in Townville
4.88 out of 5 average rating, 230 reviewsLisa’s Lodge
Jul 6 – 13
Guesthouse in Anderson
4.94 out of 5 average rating, 233 reviewsBe Our Guest
Jul 11 – 18
Guest house rentals with a patio
Guesthouse in Hartwell
4.97 out of 5 average rating, 61 reviewsOne bedroom lake front apartment with free parking
Oct 18 – 25
Guesthouse in Seneca
5.0 out of 5 average rating, 20 reviewsOne Particular Cove ... on Lake Hartwell
May 13 – 20
Guesthouse in Piedmont
4.98 out of 5 average rating, 43 reviewsShou-Sugi-Ban Retreat on the Saluda River
Jul 2 – 9
Guesthouse in Central
5.0 out of 5 average rating, 9 reviewsVacation Home Clemson and Lakes
Oct 3 – 10
Guesthouse in Pendleton
5.0 out of 5 average rating, 7 reviewsNested Studio Woodscape
May 30 – Jun 6
Guesthouse in Seneca
5.0 out of 5 average rating, 6 reviewsQuin's Lake House, Keowee. Private bottom Floor.
Jun 11 – 18
Guesthouse in Greenville
5.0 out of 5 average rating, 63 reviewsSally's Cottage
Aug 8 – 15
Guesthouse in Greenville
5.0 out of 5 average rating, 11 reviewsCasita Guest House- Country Feel- Great Location
Oct 30 – Nov 6
Guest house rentals with a washer and dryer
Guesthouse in Greenville
4.83 out of 5 average rating, 41 reviewsTheArk
Jun 26 – Jul 3
Guesthouse in Six Mile
4.89 out of 5 average rating, 97 reviewsCamper at Hickory Lodge and Guesthouse
Apr 20 – 27
Guesthouse in Anderson
4.86 out of 5 average rating, 7 reviewsCozy 2BR lakeside apt w dock near marina & Clemson
Oct 7 – 14
Guesthouse in Anderson
4.94 out of 5 average rating, 168 reviewsPrivate - Lake getaway with 7 mile view from dock
Oct 16 – 23
Guesthouse in Anderson
4.86 out of 5 average rating, 169 reviewsFarmhouse by the lake - Private guest house
Dec 22 – 29
Guesthouse in Clemson
5.0 out of 5 average rating, 6 reviewsClemson Carriage House - NEW!
Jul 11 – 18
Guesthouse in Townville
5.0 out of 5 average rating, 7 reviewsParadise Point on Lake Hartwell
Aug 21 – 28
Guesthouse in Clemson
5.0 out of 5 average rating, 9 reviewsRiggs Drive Gameday Getaway
Oct 4 – 11
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