
Vacation rentals in Wapello
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Top-rated vacation rentals in Wapello
Guests agree: these stays are highly rated for location, cleanliness, and more.

Historic West Hill Retreat
Beautiful historic 4 bedroom, 4 bath home within walking distance to shopping, bars/restaurants and all that downtown Muscatine has to offer. Enjoy sweeping views of the Mississippi River from several vantage points in and outside this home. The 3000 sf interior offers many places to gather and relax. Two of the bedrooms have on suite full baths. The other two bedrooms share a full bath. Additional amenities include, fully equipped kitchen, laundry, games, grill, outdoor entertainment area.

Riverfront Firepit, Kayaks, Huge Deck
Firepit ready for relaxing nights by the river. Kayaks included for warm days Wake up to sweeping Rock River views, sip coffee on the wrap-around deck, paddle out in the kayaks, and end your evening by the firepit as the sky glows at sunset. This eclectic riverfront bungalow blends vibrant décor with cozy comfort and seamless indoor-outdoor living. Perfect for girls’ weekends, fishing trips, romantic escapes, or peaceful fall getaways — just steps from the water and minutes to shops and dining

Farm stay close to Iowa City, IA
15 min.-Iowa City, 5 min- Riverside Casino, & 35 min-Eastern Iowa Airport, Cedar Rapids, IA. Comfy beds, living room sectional pulls out to queen hide a bed, 32 acres, horseback riding (sm. fee)*, winter fun, & fishing pond. First 2 guests pay base price, then 3rd thru 10th guests pay an extra 30.00 EACH. NO PARTIES on our farm. We live on property in a separate home. Dogs welcomed (must be kenneled when you leave property). We have an oven and cookware in kitchenette. *contact for details.

Private Guest Lake House On 37 Acres In Country
Private guest lake house, located next to main house, on private lake in the country. 2 bedroom, 1 full bath, full kitchen, washer and dryer and large attached screen porch. Private 37 acres of woods and prairie. Fishing and walking trails. Great window views of lake, woods, prairies and river valley. Please note, this guest house is located 1 mile down a county maintained gravel road. 25 minutes from Galesburg, IL, 20 minutes from Monmouth, IL and 35 minutes from Macomb, IL.

Private & Modern. Near river and wildlife refuge!
Experience the outdoors in comfort from this modern cabin, situated next to the 2200 acre Princeton Wildlife Management Area, and the nearby Mississippi River. It is ranked as the most “Wish Listed” Iowa listing of 2025 on Airbnb. Are you into hiking, biking, fishing, hunting, boating, or other water, winter, and summer sports? This cabin can support it all! Sit back and relax on the large deck while enjoying a coffee & the local wildlife, flora, & fauna of the Mississippi Valley Region.

Buckman's Bed and Breakfast (5 Bedrooms+)
Enjoy the comfort and welcoming atmosphere of a home built to entertain family & friends. There are 5 guest bedrooms rooms: Room 1-King bed, sofa bed & recliner Room 2-Queen & sofa bed Room 3-Twin beds & convertible sofa Room 4-Queen & sofa bed Room 5-King & recliner Rooms 1,2 &5 have in suite bathrooms. Bathroom for room 4 is next door. Rooms 2 &3 share an inner door; ideal for parents with children. Breakfast is included. To book a room instead of the house, see separate listings.

Cheerful Bungalow with original woodwork
This home features original woodwork, charm and character- great open front porch and back porch, living room, dining room and eat in kitchen, 3 upper level bedrooms. Full basement with laundry plus shower and stool. There is a desk for when you need a quick catch on your laptop or ipad. Relax on the porch or in the original metal kitchen with glass panels and enamel farmer sink. 1 large bedroom with queen bed and two small bedrooms with double bed Basic cable and WIFI included

Private Woodsy Cabin close to River and Keosauqua
Our cabin is located right on the edge of Lacey-State Park, with two spacious bedrooms, fully furnished living room, kitchen and bath. Sit on the deck and watch the deer walk by, enjoy the peace and quiet, with plenty of space to park your boat and recreational vehicles. Downtown Keosauqua is less than half a mile and conveniently located near all that this quaint river town has to offer - dining, shopping, bars, trails, kayaking, fishing, hunting and so much more. Pets not allowed.

Beautiful, cozy barn in the quiet countryside
Come enjoy a relaxing get away on beautiful Sugar Bottom Road. A great place for the outdoor enthusiast, no matter the season. Ideal also for quiet relaxation and privacy. We are a small acreage just 15 minutes from Iowa City, 7 minutes from Solon, and 30 minutes from the Cedar Rapids airport. Our converted barn is at the back of the property, behind the house. There is a separate road leading back to the barn for super convenient parking. It’s rustic, cozy, warm and inviting.

The Peacock Loft / Spacious Artistic Loft
A whimsical, art-filled retreat. Filled with treasured pieces from years of travel and free-spirited living, the loft is now a space for rest, inspiration, and slow mornings. Layered with color, photography, books, and meaningful objects, it’s perfect for guests who love creative, collected spaces. Please note: this is an older urban building with character, multiple stairs, no elevator, and some city noise. Fans, sound machines, blackout curtains, and earplugs are provided.

The Fleetwood Bungalow with Dreamy Porch
Welcome to The Fleetwood Inn! A charming, cozy one-bedroom bungalow in the heart of Burlington, Iowa. Right between our bustling business district and our nostalgic downtown, this little house has vast character. My favorite feature is all the original built-ins and beams. You will love the Western American inspiration and vintage finds, modern touches throughout, and dreamy details in every corner. Just added a Saatva Organic mattress for extra comfort.

The Vernon Street Guest House - Suite 2
Built in 1900 and renovated in 2022, Suite 2 shows little signs of the once quirky old space. Completely private, with all the amenities, it boasts a spacious bedroom, 1 bathroom, a fully equipped kitchen, dining area, living room with a desk for workspace, and a laundry room. While you're here, we hope you are able to relax and enjoy the well lit deck along with a cup of freshly roasted coffee, which we are happy to have provided.
Popular amenities for Wapello vacation rentals
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