Vacation rentals in Santa Fe

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Santa Fe

Guests agree: these stays are highly rated for location, cleanliness, and more.

%{current} / %{total}1 / 1
Top guest favorite
The exterior features a two-story garage structure with a metal roof and two large doors made of wood, designed with a barn-style motif. Three well-proportioned windows adorn the upper level, providing natural light, while a small weather vane rests atop the building.
Guesthouse in Webster
4.93 out of 5 average rating, 162 reviews

Clear Creek Cabin: Cozy & Quaint Rental

Cabin on Clear Creek: Our cozy, quaint and clean above-garage apartment is perfect for your short or long term rental needs. Located on a quiet, dead end street with easy access to I-45. Easy access to Houston (20 miles) and Galveston (20 Miles.) Perfect stay for your visit to NASA or Beach! Features a secured separate entrance, gated parking with remote access, one full bedroom with queen bed and ample storage, loft with a queen bed, full bathroom, full kitchen and tons of natural light.

Guest favorite
The exterior of a single-story house is shown, featuring a light-colored facade and a well-maintained lawn. Steps lead to the front porch, adorned by bushes and landscaping elements. Large windows are visible on the sides, allowing natural light into the interior.
Home in Hitchcock
4.84 out of 5 average rating, 138 reviews

Cute and Spacious Modern Home for Large Groups

Bring the whole family to this family friendly home! Huge open rooms with lots of space for fun. At just 20 minutes from Galveston, this is a great pet-friendly home for trips to the beach and for so many of the activities nearby. Check out the huge living room, large kitchen, and super clean atmosphere. We have 3 great bedrooms, and two bathrooms for large groups. Fire pit with seating , large front and back porch, plenty of space inside and out for activities. Plenty of covered parking

Top guest favorite
Home in League City
4.95 out of 5 average rating, 102 reviews

Entire Home in League City near NASA & Kemah

This hidden gem is located in the heart of League City. Serene and peaceful are a couple of ways to describe this charmer. Nestled beneath live oak and pecan trees, this home offers a spacious backyard, patio, and kayaks for guests to enjoy. Take a 2 minute stroll to Heritage Park which boasts a lovely kayak launch ramp and watch a sunset views over Clear Creek. Spend the day at nearby NASA or the Kemah Boardwalk. Not to mention, Downtown Houston and Galveston are just a short drive away.

Top guest favorite
Guesthouse in Alvin
4.97 out of 5 average rating, 234 reviews

Studio WiFi W/D Kitchen Workspace Fully Equipped

Private, serene & clean guesthouse w/everything you need in a spacious 700 sq ft. Midway Houston/Galveston • Thoughtfully cleaned by your SuperHost • Fast Wi‑Fi (532 Mbps) • In‑unit washer/dryer • Workspace • Full kitchen w/essentials • Excellent AC/Heat • Cozy couch & recliner • 55" Smart TV with Hulu & Disney+ included • Private bathroom & shower stocked with essentials • Outdoor lighted gardens w/ soothing water features Completely Detached from Main House Modern LED recessed lighting

Guest favorite
Home in Texas City
4.82 out of 5 average rating, 118 reviews

Modern Comforts Cruisers Landing

Our cozy retreat offers luxurious amenities: a soaker tub, Brand new A/C, high-speed WiFi, a 70-inch Roku TV, a chef's dream kitchen and an office set off on its own. The home is perfectly situated, a short drive from I-45 so you can quickly and easily travel North to Houston or South to Galveston. The neighborhood offers parks, ponds, walking trails and a dog park. This is the perfect spot for cruisers departing from Galveston or travelers wanting to experience the Greater Houston area.

Guest favorite
A two-story manor is seen from the river, featuring wooden stairs leading to a spacious deck. The property is surrounded by lush greenery and shaded trees, with two chairs positioned invitingly on the deck and a decorative archway enhancing the garden area.
Guest suite in Dickinson
4.81 out of 5 average rating, 144 reviews

Riverside getaway between Houston & Galveston

Riverside Manor is a peaceful retreat outside of Houston, just 15 min from NASA and Galveston island. This self enclosed Guest suite has a private entrance, bathroom and kitchenette (no full stove). Exit through the kitchenette straight down to the river, where you can relax around the fire pit, fish in the Bayou or paddle a kayak (or 3). Property is raised up amongst the trees, surrounded by nature and peace. Can sleep 4 but best suited for one couple, families or 3 close friends.

Guest favorite
The front porch is framed by green grass and decorative shrubs. A seating area with comfortable chairs is positioned under the covered section. A wooden swing set is visible in the yard, contributing to the family-friendly environment.
Home in Dickinson
4.9 out of 5 average rating, 141 reviews

Cheerful 3 bedroom home with loft

Make some memories at this unique and family-friendly place. 2 bedrooms and 2 bathrooms downstairs with a loft upstairs hosting two beds. Great for multiple families, or families with children. This updated home is cozy and bright. Great for business professionals or friends and family trying to get away. Just minutes from NASA Johnson Space Center, Clear Lake, one of the biggest yachting communities in the USA, and Galveston Island. Your home away from home awaits!

Top guest favorite
A cozy living area is furnished with comfortable gray sofas and a glass coffee table. Soft gray curtains frame the window, providing a gentle backdrop. A flat-screen TV is positioned on a sleek stand, while a light ceiling fan circulates air overhead.
Home in Santa Fe
4.91 out of 5 average rating, 69 reviews

Comfortable 3 Bedroom Home with Garage

3 bedroom 2 bath home with large fenced back yard, 2 car attached garage, and driveway parking. Family friendly and pet friendly! Make this your home base for day trips to Moody Gardens in Galveston, Great Wolf Lodge and NASA Space Center in Clear Lake, the Boardwalk in Kemah, and the Houston Zoo and Museums. My home has all the necessary amenities for a comfortable stay: 4 comfortable beds, a well stocked kitchen, central AC, laundry, dishwasher, and disposal

Guest favorite
A light-colored horse stands in a grassy area beside a winding creek, with a scenic barn and a white farmhouse visible in the background. Tall trees provide a natural border, enhancing the serene rural landscape.
Barn in Santa Fe
4.89 out of 5 average rating, 513 reviews

The Loft at Green Gables

Cozy barn apartment on a lovely small farm, secluded and quiet in the country. Located halfway between downtown Houston and the Galveston beaches, it's just a few minutes to lots of shopping and restaurants, with Kemah Boardwalk and Nasa Space Center a short drive away. Winding creek through the property, with chickens and two horses grazing in the pasture. Lots of sheep, pigs, and donkeys next door. Property has private swimming pool for your enjoyment.

Guest favorite
A spacious single-family house is set on a serene 2-acre lot, surrounded by mature trees. The front yard features a well-maintained lawn, offering ample green space. A light blue sky enhances the tranquil atmosphere, creating a peaceful setting for guests.
Home in Dickinson
4.98 out of 5 average rating, 44 reviews

Relaxing Country house close to town and shopping

A spacious country house super close to major highways for an easy commute to shopping and restaurants. The property fronts FM 646 and is 3 miles to I-45. House is tucked away from the highway frontage and located behind trees, with roughly 1 acre green space in front. You will escape from the hustle and bustle of the city, yet within 30-min away from all attractions Houston-Galveston offers: NASA Space center, Kemah, Galveston beaches.

Top guest favorite
Guesthouse in Dickinson
5 out of 5 average rating, 33 reviews

Texas Ranch Getaway | Horses, Longhorns & Quiet

Escape to Dickinson Bayou Ranch, a private guesthouse on our peaceful 60-acre working Texas ranch near Kemah, Galveston, and Houston. Overlooking the pond and riding arena, this retreat blends rustic charm with modern comfort. Explore the horse barn, greenhouse, and orchard, and enjoy quiet porch views—perfect for a relaxing getaway, romantic retreat, or stay before your Galveston cruise. Featured in Coast Monthly Magazine.

Top guest favorite
A three-story villa is displayed, featuring a modern exterior with white walls and a dark shingled roof. A landscaped yard with a stone border surrounds the entryway. A serene bayou lies adjacent to the property, with a private dock visible along the water's edge.
Villa in Dickinson
4.92 out of 5 average rating, 196 reviews

Waterfront Retreat Getaway Gameroom FirepitFishing

Enjoy a relaxing stay at the beautiful villa. It has a breathtaking view of the bayou. It is only 2 minutes away from I-45 highway, which is an easy commute to Nasa, Galveston, or Houston. As well as an outlet mall 5 minutes away. The house is equiped with a ton of amenties like fast wifi, a huge tv, a large backyard, a fire pit, a private dock, and even a kayak is provided. This unique place has a style all of its own.

Popular amenities for Santa Fe vacation rentals

  1. Airbnb
  2. United States
  3. Texas
  4. Galveston County
  5. Santa Fe