
Guesthouse vacation rentals in Santa Ana
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Top-rated guesthouse rentals in Santa Ana
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Santa Ana guesthouse rentals
Family-friendly guest house rentals

Cozy city hideaway for families.

1919 Spanish Casita | 12 min. to Anaheim

Urban Retreat

Disney Guesthouse Sleeps 7 near the Beaches in O.C

Adorable little guest house with beautiful garden

Adorable Hillside Cabin

Welcom 3bedroom,2bath guesthouse Westminster OC

Gorgeous family friendly 2 bdrm - 12 min to Disney
Guest house rentals with a patio

Luxury Cottage Near Old Town, Rosebowl, and More

An LA Escapade.

Private Spanish Guesthouse w/ Pool & Views

Adorable 1 bedroom house with pool and patio

Modern Hillside Escape surrounded by Nature

Guesthouse w/parking LA & Disneyland nearby

Runaway Inn Minutes from Claremont/Pomona Colleges

Hidden Modern Getaway
Guest house rentals with a washer and dryer

Guest Suite in Santa Ana

Beautiful Guesthouse with City Views

Villa del Sol in La Verne, CA, Private Home

Charming 2 br condo nr. beach

Cozy guest home in O.C with 2 rooms

Spacious & Central just 12 min to Disney &ConvCntr

Charming Studio Guesthouse, Ideal for OC Getaways

Stroll to Plaza or Chapman U from the ORANGE GEM
Quick stats about guesthouse rentals in Santa Ana
Total rentals
80 properties
Nightly prices starting at
€ 51 before taxes and fees
Total number of reviews
6.6K reviews
Family-friendly rentals
20 properties are a good fit for families
Pet-friendly rentals
10 properties allow pets
Rentals with dedicated workspaces
30 properties have a dedicated workspace
Destinations to explore
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- Rentals with a patio Santa Ana
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- Venice Beach
- Santa Catalina Island
- Disneyland Park
- Santa Monica Beach
- Oceanside City Beach
- Los Angeles Convention Center
- Universal Studios Hollywood
- Crypto.com Arena
- SoFi Stadium
- Hollywood Walk of Fame
- Santa Monica State Beach
- University of Southern California
- University of California, Los Angeles
- Rose Bowl Stadium
- San Clemente State Beach
- Knott’S Berry Farm
- Huntington Beach, California
- The Forum
- Bolsa Chica State Beach
- San Onofre Beach
- Oceanside Harbor
- Topanga Beach
- Disney California Adventure Park
- Pechanga Resort Casino