Vacation rentals in St. Ann

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Top-rated vacation rentals in St. Ann

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite

A well-lit living area features a dark leather sofa adorned with colorful cushions, complemented by a wooden coffee table and a blue area rug. Artwork and decorative accents enhance the space, with sunlight filtering through the windows, creating a warm, inviting atmosphere.

Apartment in Maryland Heights

4.87 out of 5 average rating, 159 reviews

KingBed Comfort-Prime Location Near CreveCoeurLake

Discover your ideal retreat in this newly renovated 2-bedroom apartment, nestled in a charming and cozy building in Maryland Heights. Just moments from Creve Coeur Lake, West Port Plaza, Hollywood Casino & Amphitheater, and the historic charm of St. Charles, this inviting space offers easy access to top dining and entertainment options. Whether you're visiting for a weekend getaway or an extended stay, every detail has been thoughtfully designed to ensure your comfort, relaxation, and enjoyment.

Guest favorite

A spacious living area features a large sectional sofa in dark leather, complemented by a coffee table and a modern floor lamp. A dining area with four chairs is visible in the background, along with a well-lit kitchen area. Neutral walls and decor create a calming environment.

Home in St. Louis

4.92 out of 5 average rating, 51 reviews

Central, Cozy & Quiet home in St. Louis.

Keep it simple at this peaceful and centrally-located 2-BR, 1-bath duplex that is charmingly furnished for a comfortable stay. This home offers warm and inviting living spaces for small families, friends, or business travelers seeking a getaway. Located right off of HWY 70 tucked off in a safe quiet neighborhood close to Lambert Airport. Only 20 minutes from downtown St. Louis and 12 minutes from Downtown St. Charles. This home offers easy access to local dining and fun entertainment options.

Top guest favorite

The charming front porch features a white wicker chair and a decorative wreath, inviting relaxation. Greenery surrounds the entryway, complemented by a well-maintained lawn. A gravel pathway leads from the porch to the driveway, creating a welcoming entrance to the guest house.

Home in Saint Charles

4.98 out of 5 average rating, 643 reviews

301 Guesthouse- Historic Main street-Katy Trail

Our 301 Guest House is new and completely remodeled in 2018! It’s ideal for one or two people with beautiful furnishings, great queen bed, lots of amenities, full kitchen, with big back yard and patio to enjoy outdoors too! Cable and FAST WiFi! Enjoy light Breakfast! BEST location, Great events year round within walking distance, with being only about 2 blocks from S. Main St, where there are about 100 gift shops n restaurants! Katy Trail is so close, with Spring, Summer, Fall and Xmas events!

Top guest favorite

The exterior of a historic log cabin features a welcoming yellow door and a decorated porch with a small table and chairs. Lush greenery surrounds the cabin, while vibrant flowers add a touch of color. The structure is complemented by the clear blue sky.

Cabin in Saint Charles

4.98 out of 5 average rating, 357 reviews

Camp Mill Pond: Historic Cabin Near Main Street

*St. Louis Magazine A-List Winner!* ***PRESS: DESIGN STL, STL MAG, AND FOX2NEWS*** Camp Mill Pond is a throwback to the slow and easy rhythm of hot summer days. This circa 1835 cabin offers easy access to our historic area, including Main Street, Katy Trail for biking, and Frenchtown, without sacrificing modern comforts! This 180-year-old historic cabin sits on a beautiful lot, shared with our 1865 three-story home and a two-story carriage house. Ask about renting bikes and a golf cart!

Guest favorite

A cozy living room is highlighted by a vintage-style mirror and decorative fireplace. Comfortable seating, including a golden armchair, is arranged around a central coffee table. Large windows allow natural light to flow in, complemented by patterned curtains and a detailed area rug.

Apartment in Southwest Garden

4.93 out of 5 average rating, 291 reviews

Historic Victorian comfort, great area

First, check out all 4 of our private 5 Star listings that creatively combines the old with the new. If one is unavailable, check the others by going to “My Profile” and scrolling down until you see all 4. This Historic building; built in 1896 has changed missions through the years; From church, to merc. Trade, to grocery store; quite the history have graced these walls. You’ll love our safe, Southwest Gardens area; next to the famous “Hill” offers unmatched restaurant, shops, bakeries

Superhost

A cozy bedroom features a spacious bed with a textured blanket and various pillows. A decorative lamp stands beside a dark dresser, while artwork depicting serene landscapes adorns the walls. Natural light enters through the window, complemented by partially closed blinds.

Apartment in St. Louis

4.87 out of 5 average rating, 39 reviews

Cozy Quiet St. Louis County Apt

Ideal for traveling professionals, travel nurses, and doctors. Cozy all brick apartment in St. Louis County is in a quiet historic neighborhood partially gated peaceful, centrally located near Christian Northeast, Barnes-Jewish, and Illinois hospitals. Minutes from Lambert Airport and University of Missouri St. Louis. GENERAL: Free WiFi, linens/towels, complimentary toiletries, iron/board, washer/dryer, central heating & A/C. We provide laundry detergent and other supplies free of charge.

Guest favorite

A cozy living area features grey walls and stylish furnishings, including a dark leather sofa and a matching armchair. A geometric area rug adds subtle color underfoot. Natural light shines through the window, and a piece of wall art adds character to the space.

Apartment in Benton Park Historic

4.97 out of 5 average rating, 220 reviews

Cozy 1BR Apartment the "Ferner Flatette"

This unique, minimalistic apartment is located in the historic Benton Park neighborhood. A stroll away from restaurants, coffee shops, antique row and the park complete with lakes and walking paths. Recently renovated, its just minutes from downtown attractions: the Gateway Arch, Busch Stadium, Enterprise Center and Union Station Aquarium. Strict capacity of 2 persons. Window unit A/C, central heat. No pets, no smoking, no local guests. Government issued photo ID required prior to checkin.

Superhost

A charming two-story house features a gray exterior, framed by vibrant trees in autumn hues. Large windows allow natural light to enter, and a welcoming entrance hints at the cozy space within. A stone pathway leads up to the home, surrounded by a rustic landscape.

Tiny home in Saint Ann

4.88 out of 5 average rating, 232 reviews

Forest Edge Tiny House | 8 Min to Airport

Welcome to a private hidden gem 8 minutes from the airport with an oasis of an acre of woods surrounding the property! It’s a quiet getaway from the hustle and bustle of the city but only 8 min to the Airport, 15 miles to down town. 15 min to St. Charles area and 10 min to Hollywood Casino Amphitheatre. Perfect for couples, small family or single visitor to St. Louis! Dogs are welcome to stay for an additional fee. Early checkin/checkout available for $15/hour as availability allows.

Superhost

A spacious living area features a mounted television above a wooden media console. Light-colored walls and hardwood flooring create an airy ambiance. A comfortable sofa is accompanied by a coffee table, while a ceiling fan adds to the inviting atmosphere. The open layout leads to a well-equipped kitchen.

Home in Saint Ann

4.79 out of 5 average rating, 34 reviews

Charming quiet 2 bedroom duplex

Unwind in the peaceful 2-bedroom, 1-bathroom duplex, beautifully furnished for a comfortable stay. This charming home offers a warm and inviting living spaces ideal for families, friends, or business travelers seeking a relaxing getaway. Enjoy a thoughtful welcome package featuring complimentary coffee, toiletries, and snacks upon arrival. Just a short 5-minute drive from the highway, this neighborhood offers easy access to local dining and entertainment options, perfect for exploring.

Guest favorite

The exterior features a basement-level entrance framed by a concrete pathway. Large windows provide natural light, while a well-maintained grassy area surrounds the entrance. The building's siding is light-colored, and a light fixture is mounted above the door.

Guest suite in Florissant

4.83 out of 5 average rating, 134 reviews

Peaceful lower level apt in wooded neighborhood

A self contained apartment located in the basement of our home. 2 private entrances, self check-in and check-out. The neighbors in our cul-de-sac are trees and cardinals (the birds not the baseball players.) Quiet enough to work, work, work. Spacious enough to play, play, play. Christian Hospital 6 min, Airport 17 min, Busch Stadium 24 min, Convention Plaza 24 min, Downtown St. Louis 25 min. Very near nature reserves and confluence of Missouri and Mississippi Rivers.

Guest favorite

A vibrant living area features bright green sofas with pink accent pillows positioned around a colorful area rug. An archway leads to a dining space with orange chairs, while blue walls and purple curtains add modern charm.

Bungalow in St. Louis

4.94 out of 5 average rating, 115 reviews

Family & Pet Retreat Near STL Airport & Highways

10% of our net profits support local rescues & animal outreach! 🐾 Pet-friendly 2-bed, 1-bath home with fenced yard, coffee bar, and dog gear—bowls, toys, waste bags. Bring up to 2 friendly pups ($85 per pet). Near highways 364, 170 & 70. 6 mins to UMSL, 9 mins to Lambert Airport, 12 mins to Delmar Loop, 15 min to STL Zoo & The Hill, 20 min to hospitals( Barnes Jewish/Childrens) & Arch. *Due to local Airbnb regulations, guests must provide some additional info after booking.

Top guest favorite

A bright living space is presented with a comfortable gray sofa and a round wooden coffee table. A washer and dryer are situated under the staircase, and two potted plants enhance the decor. Natural light enters through multiple windows, illuminating the area.

Cottage in Maplewood

4.99 out of 5 average rating, 472 reviews

Weaver Guest House

This charming, light-filled cottage feels like its own private hideaway, yet it's close to everything St. Louis has to offer. Tucked between trees in a quiet Maplewood neighborhood, it's a 15-minute walk to the MetroLink and a 10-minute drive to Washington University, Webster University, Fontbonne University, Forest Park, and Clayton. Business travelers and families alike will appreciate the washer/dryer, fast WIFI and cable TV.