Vacation rentals in Pine Island

Bright 2BR Suite | Minutes from Mayo Clinic

Stay comfortably in Rochester with all the conveniences of home. Whether you're visiting Mayo Clinic, traveling for work, relocating, or simply exploring the area, this bright and modern furnished suite offers everything needed for a stress-free stay. Enjoy a living space filled with natural light, fully equipped kitchen with full-size appliances, and an in-suite washer and dryer. WiFi, comfortable furnishings, and thoughtful spaces make this suite ideal for both short visits and extended stays.

Zumbro Lake Home

Relax with the whole family, plan an ice fishing trip with your buddies, or enjoy the lake between clinic appointments. Large lawn with 160ft lake front perfect for swimming, kayaking, fishing, or just relaxing by the water. Full kitchen, laundry, 2 full bathrooms, 2 bedrooms, 2 queen beds and twin bunkbeds in the main house. A second, separate building referred to as the "Bunkhouse" features 3 double beds upstairs and a 2 double beds in the lower level. Within 20 minutes of the Mayo Clinic.

4BR Modern Home, Hot Tub, Fire Table & Family Room

Discover your perfect family/group retreat: *beautifully remodeled farmhouse *nestled directly across from the Zumbrota Golf Course *sleeps 9 guests 4 queen bedrooms | single bed in family room *relax in the cozy living room *family room on the 3rd floor *hottub, expansive deck, and enclosed screened in porch *30 min to Rochester(Mayo Clinic, Apache Mall, and more) *Approx 1 hour to the Twin Cities (Minneapolis & St. Paul), offering major attractions, sporting events, and cultural experiences

Home Calls the Heart- 10min to Mayo

1/2 block from HWY 52, serene and peaceful split level home. 10 min to Mayo Clinic & St. Mary's Hospital. Fully furnished, convenient and ideal for families & professionals for the home away from home feel. Luxury Sheets and Posturepedic . Fully equipped with various kitchen appliances and utensils. Minutes to parks, groceries, shopping etc. Wifi, Roku Smart TV & cable. Phone call away if you have any issues while staying at our charming home. No pets due to Mayo Clinic guests’ allergies.

New! MN Comforts The Heart 4Bd/2Bth, 12min to Mayo

Welcome to MN Comforts The Heart! Are you here for work or leisure, or want to feel comforted after a Mayo appts? 12 min to Mayo Clinic, Wifi, work-station, ROKU/Smart TVs, and a fireplace in the family room. We offer a 2nd home feel. Near stores. Split-level, chill, and quiet, thoughtfully designed to cater to your needs, ensuring a comfortable, enjoyable stay. A blend of traditional & modern styling in a tranquil home, with fun opportunities for family & friends. Fully fenced backyard.

Oasis - Comfort & Serenity (Full house near Mayo)

*Discount for extended stays* Seeking a peaceful respite near Mayo Clinic in Rochester, MN? Look no further than "Oasis"–your ultimate home away from home. We offer 5 beds, 2 baths, & can accommodate up to 8 guests. Recharge in the workout & yoga meditation room, stay connected in the office area, & explore Rochester's attractions. Your dedicated host Peggy, a Mayo employee, will ensure a seamless/enjoyable stay. Book now & experience the perfect blend of comfort & serenity at Oasis.

Near Mayo Family Friendly / 5 beds 2 baths CLEAN

Nestled in the cul-de-sac of Arcon Lane in the northwest side of Rochester, Minnesota, an Airbnb was established in the summer of 2025. It was given a name called Arcon Hollow B&B. Arcon Hollow B&B can be whatever space you’d like it to be for your stay. It can be your peace and quiet space away from the chaos of life, your rest and restore atmosphere to renew your energy, or your home away from home for different reasons that bring you to our beautiful town Rochester, Minnesota.

Zumbro Valley Getaway

Enjoy your stay at our bright two-bedroom+ apartment! Located in the beautiful Zumbro River Valley, you are near the Zumbo River, popular for kayaking, tubing and fishing, and many scenic roads for biking and cruising. Rochester is 30 minutes away as is the Mississippi River and its river towns. A long, but gentle boardwalk takes you up to this apartment. Wonderful location to spend time with family and friends, or to getaway and enjoy the beauty of the driftless region.

Our Happy Place

Welcome to our happy place. Forget your worries in this spacious and serene space. Enjoy the views and the company on the deck. You will be steps from the water where you can catch some rays or fish off the dock. Unwind at our cozy cabin with the convenience of being 20 min away from Rochester. Take in some live music or people watching at any of the 3 bars on the lake, all a short driving distance away. Boat rentals are also available at Kings Marina.

The Flipping RV: Lake Zumbro

Get outdoors and reconnect with nature at this unforgettable escape 20 minutes from Rochester! Enjoy s'mores by the campfire, lakeside swimming, and spending quality time with the people you love. This RV offers three beds - one queen, one full, and one twin, one bathroom with a shower/tub, and a full kitchen. A TV that offers streaming services and WIFI. Outdoor games, paddle boards, and more! Additional offerings include ice and firewood.

The Sierra! Close to Mayo Clinic

Gorgeous Home close to Mayo Clinic. The family room and living include Roku 4K UHD TVs, Foosball, and darts. Free WIFI. Office on Main with great light. Beautiful front porch or patio in the rear. TVs Enjoy luxurious finishes like crown molding, a fireplace in the family room, quartz countertops and a stunning vaulted Primary Ensuite with custom tile work and paneled doors. All of this is conveniently just minutes from downtown!

1st Premium Luxury Rooftop Stay w/ Elevator

Experience family fun in this stylish new model home featuring four bedrooms and four bathrooms. Enjoy a rooftop patio, an elevator, and a spacious primary suite with stunning views. The elevator provides easy access to all levels, making grocery trips a breeze from the two-car garage. Conveniently located just 12 minutes from the Mayo Clinic, this home showcases luxurious finishes throughout.