
Guesthouse vacation rentals in Orange County
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Top-rated guesthouse rentals in Orange County
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Orange County guesthouse rentals
Family-friendly guest house rentals

Eclectic Forest View Efficiency in Chapel Hill

Cute Downtown Carrboro Studio Cottage

Studio on Tobacco Road

Urban homesteading in Carrboro

The Store in Hobo, a reader/writer’s retreat.

Separate In-Law Suite in Carrboro

CFCB cabin retreat minutes from Duke, NCCU, & UNC

Best location! Clean, beautiful, walkable cottage.
Guest house rentals with a patio

"Wit's End" welcomes you! 2BR comfy guest house

Carolina Cottage

Duke Forest Hideaway

RakShack Studio

Charming -Stylish Studio Min to Downtown 1Durham

Guesthouse in the heart of South Durham

Boarding House

New Apt- walk to everything Rockwood
Guest house rentals with a washer and dryer

Guest House on the Cary Downtown Park!

Central to Everything, Renovated, Dog Friendly.

The Sacred Cedar, your sanctuary 15min from UNC

Duplex filled with natural light

Beautiful Alley House 2 Blocks to Duke + Downtown.

Tilly Guest House - Downtown Apex

Entire Apt: Amazing Walkability + Quiet Street

Private 'Barn'dominium with No Cleaning Fee!
Destinations to explore
- Cabin rentals Orange County
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- Rentals with lake access Orange County
- Apartment rentals Orange County
- Rentals with an EV charger Orange County
- Rentals with a fire pit Orange County
- Rentals with a washer and dryer Orange County
- Condo rentals Orange County
- House rentals Orange County
- Waterfront rentals Orange County
- Pet-friendly rentals Orange County
- Rentals with pools Orange County
- Rentals with a fireplace Orange County
- Rentals with outdoor seating Orange County
- Private suite rentals Orange County
- Fitness-friendly rentals Orange County
- Rentals with breakfast Orange County
- Rentals with a patio Orange County
- Family-friendly rentals Orange County
- Guesthouse rentals North Carolina
- Guesthouse rentals United States
- PNC Arena
- Duke University
- North Carolina Zoo
- Wet'n Wild Emerald Pointe Water Park
- Durham Bulls Athletic Park
- Raven Rock State Park
- Sedgefield Country Club
- Frankie's Fun Park
- Greensboro Science Center
- American Tobacco Campus
- Eno River State Park
- Lake Johnson Park
- North Carolina Museum of Natural Sciences
- William B. Umstead State Park
- Carolina Theatre
- North Carolina Museum of History
- Starmount Forest Country Club
- North Carolina Museum of Art
- Sarah P. Duke Gardens
- Tobacco Road Golf Club
- Gregg Museum of Art & Design
- International Civil Rights Center & Museum
- Gillespie Golf Course
- Durham Farmers' Market