Become a host

Boutique hotel vacation rentals in Ohio River

Find and book unique boutique hotel rentals on Airbnb

Top-rated boutique hotel rentals in Ohio River

Guests agree: these boutique hotel rentals are highly rated for location, cleanliness, and more.

%{current} / %{total}1 / 1
Guest favorite
The suite features a queen four-poster canopy bed with luxurious linens. A chandelier hangs above, illuminating the room. A cozy seating area includes a patterned armchair and a small table, complemented by lamps and a decorative plant by the window.
Hotel room in Bardstown
4.88 out of 5 average rating, 147 reviews

Luxurious Suite w/garden on Court Square Downtown

The Chapeze Suite is located inside the Kentucky Bourbon House, circa 1789. The first floor suite features a queen four post canopy bed with luxurious linens. The Master Bathroom has a shower, towels and robes. Sip on a cup of our famous Bourbon Coffee in the morning or relax with your favorite bourbon cocktail under the lights in your private garden. The suite is just a few steps from the court square in downtown so you are right in heart of all shopping, dining, bars and nightlife...cheers!

Top guest favorite
A screened porch features comfortable seating with red cushions, arranged around a central coffee table. A decorative area rug complements the space, while natural light streams in through two large windows, casting patterned shadows on the floor.
Hotel room in Newport
4.96 out of 5 average rating, 587 reviews

#5 No Cleaning/Parking Fees! Walk to Games/Music!

Legal Airbnb, with a 96% Five Star Rating! Super Host Status! 634 Orchard St. Our first floor studio apartment is 3 blocks to Newport on the Levee, or a 20 min. walk to DT Cincinnati/REDS/Bengals games. Surrounded by great restaurants, nightlife, and, family activities. Close to aquarium, stadiums, shopping and concert venues. You’ll love the ambiance, the lively neighborhood, the people! It will all give you a historic perspective of this quaint town! BAR NO CLEANING FEE! FREE PARKING! 21 Y

Superhost
A compact suite corner is visible, featuring a twin bed with neatly arranged linens. A mini-fridge, microwave, and coffee maker are positioned beneath a wall-mounted television. A closet with shelf space and additional pillows is shown, along with a clear view of the adjoining bathroom door.
Hotel room in Nashville
4.83 out of 5 average rating, 170 reviews

Historic Campus Suite on Music Row, near Broadway!

Welcome to Scarritt Bennett. Come stay in a piece of history while enjoying the city of Nashville just steps outside your door. Our space is on Music Row, a block from Vanderbilt, and minutes from Belmont, Lipscomb, Hillsboro Village, 12S, Midtown, Honky Tonk Row and more! • Walkable to restaurants & bars • Budget-friendly • Keypad entry • Free parking on-site • Free Wi-Fi • Check-in at 4 pm // Check out at 10 am • No smoking or alcohol allowed PLEASE READ THE LISTING FULLY BEFORE BOOKING.

Top guest favorite
A bright bedroom features a spacious bed with crisp white linens and a decorative headboard. Large windows provide ample natural light and showcase mountain views. A TV is positioned on a dresser, while a comfortable chair and a small table are situated beside the door leading to the patio.
Hotel room in Westfield
4.95 out of 5 average rating, 182 reviews

Bedroom 9 - The Big Creek Lodge

Bedroom 9 is up a flight of stairs in the The Big Creek Lodge on the 350 acre Luna's Trail property. Guests will enjoy beautiful views of Hanging Rock and Pilot Mountain from their private patio, a claw foot tub, and a walk in shower. Our restaurant is available Thursday - Sunday. Reservations are recommended but not required for on property guests and can be made by contacting the owners. There are sometimes large, private events downstairs. Please ask ahead if one may affect your visit.

Guest favorite
A Lotus stargazing tent is positioned on a wooden deck, surrounded by natural foliage. The structure features a wooden frame with mesh sides, allowing for a connection to the outdoors. Soft orange drapes extend over the tent, creating a cozy and inviting atmosphere.
Hotel room in Stanton
4.89 out of 5 average rating, 95 reviews

The Hive at high Rock - The Outer Reaches

Come spend a night under the stars in one of our split unit and mattress pad HEATED Lotus stargazing tents nestled on four lush hillside acres backing Daniel Boone National Forest . Curated by local artists to inspire creativity, passion and relaxation. Less than 20 minutes from the center of Slade, dubbed the “Gateway to the Gorge” where you will find endless hiking trails, water falls, natural arches, dining and world renowned rock climbing. Relax, take a deep breath and REWILD your soul.

Top guest favorite
The exterior of Duck Creek Farm and Inn is highlighted, showcasing a two-story structure with a green metal roof and light brown siding. A sign displays the inn's name on the front, with a decorative star on the side. Stairs lead to the upper level.
Hotel room in Metamora
4.93 out of 5 average rating, 41 reviews

Khaki Suite

Welcome to Duck Creek Farm and Inn, a charming place offering four beautiful guest rooms in the picturesque hills of Southeastern IN. Our spacious family friendly rooms are thoughtfully decorated with luxurious linens on comfy beds. Each room features pleasant views, a private bathroom, and a cozy sitting area. Unwind, relax, and rejuvenate while enjoying the comfort and hospitality we are known for at our beautiful countryside inn where you will arrive strangers but leave as friends.

Top guest favorite
The exterior of Duck Creek Inn is depicted, showcasing a charming two-story structure with a green metal roof and wooden siding. A weather vane adorns the peak, while stairs lead to a second-level balcony. A star accent is positioned on the side wall, complemented by a welcoming sign.
Hotel room in Metamora
4.94 out of 5 average rating, 53 reviews

Mallard Family Suite

Welcome to Duck Creek Farm and Inn, a charming place offering four beautiful guest rooms in the picturesque hills of Southeastern IN. Our spacious family friendly rooms are thoughtfully decorated with luxurious linens on comfy beds. Each room features pleasant views, a private bathroom, and a cozy sitting area. Unwind, relax, and rejuvenate while enjoying the comfort and hospitality we are known for at our beautiful countryside inn where you will arrive strangers but leave as friends.

Guest favorite
A spacious bedroom features a full bed covered with a patchwork quilt. Large windows allow natural light to fill the room, and a vintage fireplace adds character. A ceiling fan and wall sconces provide additional lighting, while hardwood floors enhance the inviting atmosphere.
Hotel room in Chillicothe
4.81 out of 5 average rating, 263 reviews

The Historic Ohio Motel - Room 7

Welcome to our Airbnb, The Historic Ohio Motel. The home was built around 1897 by Fred A. Stacey and was in his estate until 1950. At that time Harold White opened it as the Ohio motel. It operated as Ohio Motel until the sale in 1984. We invite you to stay and hope you will appreciate the craftmanship as much as we do. From the built in pocket doors to the stained glass windows, it's an example of craftsmanship of days gone by. we welcome you to visit and see for yourself. #65716

Guest favorite
A cozy living area is highlighted by a tan leather sectional sofa positioned against a light-colored wall. A round black coffee table sits atop a textured blue rug. A potted plant adds a touch of greenery, while modern light fixtures hang gracefully from the ceiling.
Hotel room in Prospect
5 out of 5 average rating, 13 reviews

The Plume at The Purple Martin in Louisville

The Purple Martin is a charming boutique hotel located in the premier neighborhood of Norton Commons in Louisville, Kentucky. Known for its fine dining and exciting nightlife, Louisville offers a plethora of attractions for guests to explore and the Purple Martin is in the perfect centralized location for your stay. The rooms at The Purple Martin are elegantly furnished and decorated with all the amenities needed for a comfortable stay. Guests can relax in style and luxury!

Top guest favorite
The living room features a dark leather sofa adorned with yellow cushions, complemented by two orange chairs and a coffee table. A large mirror and a selection of framed artwork are displayed on the walls. Natural light filters in through window treatments, enhancing the inviting space.
Hotel room in Versailles
5 out of 5 average rating, 13 reviews

Pappy VanWinkle Suite, The Woodford Hotel

Renovated building built in 1880's in the heart of downtown Versailles. Pappy VanWinkle • 1 Bedroom/King Bed, 1Full bathroom • Full Kitchen • Living Room • 2 Smart TV's • Onsite parking Walking distance to coffee shops, restaurants, bourbon bar, bakery. 11 min to Keeneland 15 min to Distilleries 12 min to Lexington Airport 50 miles to Louisville *Offsite Amenities- public pool & boat dock. Please refer to Location Activities section for details. Rental agreement required

Guest favorite
The exterior of The Sherman Inn displays a charming half-timbered design with a distinctive peaked roof. Lush greenery, including a pine tree and flowering bushes, complements the inviting facade, while a sign marking the inn's name hangs prominently above the entrance.
Hotel room in Batesville
5 out of 5 average rating, 9 reviews

The Sherman Inn King

The Sherman Inn is over 170 years old recently renovated to include all modern travel amenities. Located roughly half-way between Indianapolis and Cincinnati, the inn is the perfect meeting place and near many sights and activities within walking distance. All 22 boutique guest rooms are unique from each other and include wood floors, marble bath floors, walk-in tiled showers, custom shutters and the best mattresses for a great night's rest.

Guest favorite
A cozy sleeping area showcases a spacious bed with crisp white linens. Elegant round wall art made from natural materials complements the dark blue backdrop, while two stylish bedside lamps provide soft illumination on either side.
Hotel room in Nashville
4.82 out of 5 average rating, 1,062 reviews

2BR Suite: Walk Downtown, Full Kitchen & Living

Celebrate the city and your time together with a little more space in our Two Bedroom, One Bathroom Suite. Give yourself room to spread out or bring some friends and family, with 900 sq ft and two bedrooms with king-sized beds, including in-kitchen dining, a cozy living room, balcony or patio, a bathroom, and optional city views. The two bedroom sleeps up to four people, so make a friend’s day and invite them along for the adventure.

Popular amenities for Ohio River boutique hotel rentals

Kitchen
Wifi
Pool
Free parking on premises
Air conditioning

Family-friendly boutique hotels rentals

A spacious bedroom features a King-sized bed with a velvet headboard, accompanied by a cozy seating area. Large windows invite natural light, with curtains softly framing the view. A plush area rug complements the hardwood flooring, and a small table with upholstered chairs adds functionality.
Hotel room in Louisville
4.89 out of 5 average rating, 106 reviews

The Olmsted Suite 101 at The Bellwether Hotel

A welcoming sign for the Pine Mountain Inn is prominently displayed in front of the building. The sign features the words 'Welcome' and 'Pine Mountain Inn,' with 'Vacancy' indicated below. The inn's brick exterior and well-manicured shrubs complement the inviting entrance.
Hotel room in Pineville
4.52 out of 5 average rating, 23 reviews

Rm 3-Pine Mtn Inn, Laurel Cove, Bell Theater & LMU

Top guest favorite
A pair of ornate, burgundy chairs frame a small, round wooden table, which holds two glasses and a decorative lamp. The background features an antique bed and walls adorned with various framed portraits and art pieces, contributing to a vintage atmosphere.
Hotel room in Fayetteville
4.97 out of 5 average rating, 30 reviews

Historic Harvey House Inn- Library Room

A private room features a full-sized bed covered with a colorful quilt, complemented by a patterned area rug underneath. A swivel chair is positioned nearby, and a bathroom door is partially visible in the background. The wooden flooring adds warmth to the space.
Hotel room in Circleville
4.62 out of 5 average rating, 616 reviews

The Guest House

Superhost
A small guest room features a full-size bed with white bedding and a light green throw. A bedside table with a lamp is adjacent to the bed. An air conditioning unit is positioned near a window with sheer curtains. The en-suite bathroom is visible through an open doorway.
Hotel room in Leitchfield
4.95 out of 5 average rating, 40 reviews

Pistachio Mini Room @ Twin Lakes Creamery

A queen room features two spacious queen beds with minimalist bedding. Soft, indirect lighting highlights the room's modern aesthetic. A mirror is positioned above the bathroom sink, and light wood flooring complements the overall design.
Hotel room in Nashville
4.7 out of 5 average rating, 88 reviews

The Rose Room at the Iris Motel!

Top guest favorite
A spacious bedroom is furnished with a comfortable bed, complemented by a decorative throw blanket. Natural light is welcomed through large windows, which overlook a vibrant outdoor view. A small dining table with two chairs is positioned nearby, enhancing the room's functionality.
Hotel room in Tiffin
4.96 out of 5 average rating, 75 reviews

Renovated Italianate Cottage room @ Frost Village

Superhost
Hotel room in Gilbertsville
4.68 out of 5 average rating, 25 reviews

Motel at KY Lake. Reel & Relax

Boutique hotels rentals with a patio

Guest favorite
A historic guest room features a prominent black cell door, flanked by colorful banners and wall decor showcasing past visitors' signatures. A comfortable chair and a black bench provide seating, while a bed is located against the far wall, offering a glimpse into the room's unique history.
Hotel room in Rockville
4.92 out of 5 average rating, 25 reviews

The Old Jail Inn - Harley Davidson Suite

A bright bedroom with white walls features a cozy queen bed layered with a white duvet and a textured green throw. Two windows allow natural light to fill the space, complemented by a ceiling fan. A bedside table and accent chair provide additional comfort.
Hotel room in Boone
4.82 out of 5 average rating, 87 reviews

Sage Suite at The Wanderer

Superhost
The exterior of a two-story motel is visible, featuring a balcony adorned with American flags and decorative bunting. A concrete walkway leads to the entrance, flanked by potted plants. Large windows provide ample natural light to the interior spaces.
Hotel room in Falls of Rough
4.69 out of 5 average rating, 26 reviews

Quiet, peaceful motel next to Rough River Dam.

Superhost
The exterior of the Blue Ridge Tourist Court features a retro-style building with colorful doors in pastel shades. A white vehicle is parked in front of the motel, which is surrounded by landscaped greenery and vibrant flower beds. The welcoming sign is prominently displayed.
Hotel room in Boone

Junior Suite - Blue Ridge Tourist Court

Guest favorite
A light-filled queen room features a floral patterned bedspread on a spacious bed. A vintage-style armchair sits in the corner, and a television is positioned on a white dresser. Soft curtains frame the window, inviting natural light into the tranquil space.
Hotel room in Wooster
5 out of 5 average rating, 13 reviews

College of Wooster - Roble Queen Room

Guest favorite
A spacious outdoor area overlooks a serene river. String lights are suspended overhead, illuminating the scene. A decorative table is surrounded by chairs, inviting relaxation among lush greenery. The tranquil waterway and landscaped gardens contribute to a peaceful atmosphere.
Hotel room in Indianapolis
4.94 out of 5 average rating, 16 reviews

Cozy River Retreat

Guest favorite
A well-lit sleeping area features two plaid-covered beds positioned parallel to each other. A desk chair is visible beside a window adorned with a sheer curtain, allowing natural light to fill the room. A wooden table stands against the wall, creating a functional space.
Hotel room in London
4.95 out of 5 average rating, 43 reviews

London Guest House - Suite 1

Guest favorite
The entrance to the queen room named 'Rincón' is visible, with a view of the inviting bedroom. A spacious bed is adorned with a decorative quilt, while a television is mounted on the wall opposite a dresser. Natural light enters through a window dressed in sheer curtains.
Hotel room in Wooster
4.89 out of 5 average rating, 18 reviews

College of Wooster - Rincón Queen Room

Other boutique hotel vacation rentals

The house is nestled among a well-maintained lawn, featuring a light-colored facade and a welcoming porch with seating. A pink flowering tree is prominently in the foreground, contrasting with the vibrant green grass and surrounding greenery.
Hotel room in Bloomington
5 out of 5 average rating, 13 reviews

Wampler House; Barrett Room - King Size Bed, Fireplace, Jacuzzi Tub, Breakfast

The living area features exposed wooden beams and brick walls, creating a cozy environment. A gray sofa is accompanied by two patterned armchairs, all arranged around a coffee table. Soft lighting from lamps enhances the warmth of the space, while an open kitchen is visible in the background.
Hotel room in Salem
4.93 out of 5 average rating, 70 reviews

The Lofts at Downtown Salem

Guest favorite
A tranquil winter scene is depicted, showcasing a covered bridge spanning a gentle stream. Snow blankets the surrounding landscape, highlighting a charming building nestled among the trees in the background, reflecting a serene winter retreat.
Hotel room in Slaty Fork
5 out of 5 average rating, 14 reviews

Morning Glory Inn Snowshoe/Cass Room 205

Guest favorite
A living room area features a stylish black leather seating arrangement around a circular coffee table. A decorative wall showcases floral artwork with warm lighting. To the side, a kitchenette is equipped with a mini refrigerator and glassware. Natural light filters through the windows, accentuated by checked drapes.
Hotel room in Versailles
4.91 out of 5 average rating, 22 reviews

Four Roses Suite, The Woodford Hotel

A spacious bedroom features an ornate four-poster bed framed by tall wooden columns. Soft, neutral bedding is paired with decorative pillows. Natural light enters through large windows dressed in sheer curtains, while an elegant chandelier hangs above. A vintage chair and a small side table complement the setting.
Hotel room in Fort Wayne
4.88 out of 5 average rating, 344 reviews

Historic Honeymoon Suite | 2 Person Jacuzzi Tub

Superhost
Hotel room in Millersburg
5 out of 5 average rating, 6 reviews

Seabiscuit Suite | Classic Historic Stay, King Bed

Guest favorite
A spacious bedroom features a king size bed with crisp white linens, a large wall-mounted TV, and a modern desk with a chair. The light green walls create a calming atmosphere, while a doorway leads to the kitchenette area, suggesting convenience for guests.
Hotel room in Bowling Green
4.95 out of 5 average rating, 59 reviews

Consistently Great The Hotel SYNC KDS

Guest favorite
A cozy living room features a gray sofa accompanied by two brown leather chairs. A round table sits nearby, complemented by decorative checkered curtains framing the windows. A large artwork and wall plates enhance the space, while a chandelier adds subtle warmth.
Hotel room in Versailles
5 out of 5 average rating, 14 reviews

EH Taylor Suite, The Woodford Hotel

Destinations to explore