Vacation rentals in Murphysboro

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Top-rated vacation rentals in Murphysboro

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Guest favorite

Condo in Murphysboro

5.0 out of 5 average rating, 32 reviews

2 Bed 1.5 Bath Condo

WE’RE BACK! After 3 years we have decided to host again. For those that have stayed in the past, this is located just next door to our previous location. We have a newly renovated 2 bedroom, 1.5 bath condo with WIFI located just 2 blocks off Walnut Street. Walking distance or just a short drive to many locally owned shops, restaurants, wine trails, lakes (both Kinkaid and Murphysboro lakes), SIU and breweries. Queen beds and TV's with Roku in both bedrooms. USB charging ports in both bedrooms.

Jan 16 – 23

€ 100 per night

Guest favorite

Home in Murphysboro

4.88 out of 5 average rating, 86 reviews

Home Away From Home

Enjoy our cozy 2 bedroom home, the sofa bed lets larger families enjoy their stay too. For 6 adults it may be a bit tight but we have had 7 guests in the past. A well equipped kitchen has the laundry. Fully stocked fridge for breakfast. There’s a covered patio and carport. House is in a quiet residential area only a short drive to restaurants, antique & specialty shops. Beautiful hiking trails, lakes, orchards, SIU Campus, ShawneeWine Trail, Microbreweries & many other sights await your visit.

Feb 13 – 20

€ 108 per night

Guest favorite

Guesthouse in Carbondale

5.0 out of 5 average rating, 174 reviews

Homestead Cottage

Enjoy tiny farmhouse life in this adorable 375 sq. foot cottage. Loaded with everything you need this little cottage is nestled privately behind some trees on our 11 acre farm. You will soon forget how close you are to town with the beautiful view from your windows and the pasture fence just steps out the back door. Whether you’re here for the wineries, amazing hiking, an SIU event (3 miles) or to visit with family, the Homestead Cottage will provide a comfortable retreat from any adventure.

Sep 2 – 9

€ 90 per night

Guest favorite

Apartment in Carbondale

4.95 out of 5 average rating, 147 reviews

Carbondale home in gorgeous country setting

Welcome to Portas Caeli: a cozy, one bedroom, one bath apartment made to make you feel at home. Sitting just outside of Carbondale City limits, our guests enjoy the relaxing country setting only 5.3 miles from SIU, near downtown Carbondale, and close to the So. IL Wine Trail. Giant City Park is less than 5 miles down the road with its many beautiful hiking trails. Walk through our 20 acres, relax and watch deer graze on the fields. Sit under the gazebo and read a book. Hosts live next door.

Oct 6 – 13

€ 97 per night

Guest favorite

Place to stay in Makanda

4.93 out of 5 average rating, 159 reviews

Maple Ridge Cabin at Panther’s Rest

Secluded, yet convenient, we’re within 5 min of two wineries, ziplining, trail heads, and I-57. This is your unforgettable romantic wine country retreat or comfortable rest after hiking or travel. There is no TV or Wi-Fi (good cell signal though) but that is not why you’re here! Explore the vineyards, walk the trails, and drink complementary on-farm roasted coffee! Your pet is welcome when you add them to the reservation. Maple Ridge Cabin is your gateway to the Shawnee Wine Country!

Dec 24 – 31

€ 154 per night

Guest favorite

Place to stay in Cobden

4.95 out of 5 average rating, 272 reviews

Eva's Roost Retreat - Center For Lost Arts

Eva's Roost -a uniquely crafted rustic, zen-style cottage, designed to be close to the earth & nature. Expensive curtainless windows facing the forest & pond allow for private views: sunrise, moonrise, forest & wildlife. Personal outdoor space with firepit & comfy adirondack chairs. Paul is the architect & designer of Center For Lost Arts structures, furniture & grounds. Bonnie is a mindfulness meditation teacher who enjoys creating a welcoming space for all to enjoy year-round.

May 29 – Jun 5

€ 118 per night

Guest favorite

Cabin in Alto Pass

5.0 out of 5 average rating, 110 reviews

Bald Knob Cabin

Located in heart of Shawnee National Forest, Bald Knob Wilderness and River To River Trail , is a former orchard turned cozy hiker/biker haven. Just 2 miles down the road from Bald Knob Cross of Peace. This studio style cabin was recently renovated and has a fully functioning kitchen. Bald Knob Cabin is the ideal location to unplug and put your feet up after a long day hiking trails or traveling the Shawnee Wine Trail that flows through the cozy, inviting town of Alto Pass.

Jun 30 – Jul 7

€ 121 per night

Guest favorite

Cabin in Alto Pass

4.99 out of 5 average rating, 212 reviews

Ma's Cabin, Alto Pass, IL. Fine country lodging.

Cute and country remodel done in 2019. Recent new appliances, furnishings, flooring, heat & A/C, washer & dryer. Cabin is secluded and quiet plus 1/2 mile from Alto Pass Lookout Point and right in the middle of many award winning wineries. 15 miles from Carbondale 4 miles from Giant City 30 miles from Garden of the Gods 6 lakes within 10 mile radius Hundreds of miles of hiking trails in nearby Shawnee National Forest 6 miles from Bald Knob Cross Please, no dogs!

Feb 24 – Mar 3

€ 87 per night

Guest favorite

Treehouse in Makanda

4.98 out of 5 average rating, 177 reviews

Panthers Inn Treehouse

Come nestle amongst the leaves at Panthers Inn Treehouse. This secluded, well equipped, elevated cabin has the perfect combination of natural beauty and artful luxury. Isolated yet conveniently located 2 minutes from Blue Sky and Feather Hill wineries, within 5 minutes of Panthers Den hiking trail and the Shawnee Hills canopy tour and only 10 min from I-57 exit 40. Panthers Inn is the perfect starting and ending point to your Shawnee Hills Wine Country vacation!

Jan 31 – Feb 7

€ 162 per night

Guest favorite

Home in Carterville

4.91 out of 5 average rating, 293 reviews

Newly Updated Family Home in Carterville

This cozy 3 bedroom 2 bath house can easily house your family on your future trip to Southern Illinois. The home is conveniently located within a short drive of Marion, Carbondale and the Wine Trail. We look forward to hosting you on your future visit. We are currently updating the house regularly between bookings, the furniture and fixtures may change for the better between the time of booking and your stay.

Jun 30 – Jul 7

€ 132 per night

Guest favorite

Cabin in Du Quoin

4.98 out of 5 average rating, 121 reviews

H & B's...Come experience the magic of nature!

The Cabin is nestled in the woods, a few hundred feet from a beautiful private lake. If it's total solitude you are looking for, this is the place. Keyless entry makes it perfect if you want total privacy. If you want lake access, come down and have coffee with us for orientation. Our pantry items, coffee, granola, half & half, and spices are perfect for your full-service kitchen.

Jul 27 – Aug 3

€ 101 per night

Guest favorite

Cabin in Makanda

4.98 out of 5 average rating, 165 reviews

The Farmhouse at Black Jack Vineyard

Turn of the century farmhouse located on a 60 acre private vineyard. Minutes from SIU campus and in the heart of the Shawnee Wine Trail. This recently updated 2 bedroom 1 bath in a country setting will allow you to relax with the sounds of nature.

May 15 – 22

€ 143 per night

Vacation rentals for every style

Get the amount of space that is right for you

Popular amenities for Murphysboro vacation rentals

Kitchen

Wifi

Pool

Free parking on premises

Air conditioning

Stay near Murphysboro's top sights

17th Street Barbecue30 locals recommend

Cindy B's Cafe3 locals recommend

Cummares8 locals recommend

Molly's Pint Brewpub3 locals recommend

Brews Brothers Taproom6 locals recommend

Big Muddy Brewing13 locals recommend

Other great vacation rentals in Murphysboro

Guest favorite

Home in Murphysboro

4.98 out of 5 average rating, 51 reviews

Mary and Snooks' Cozy Country Farm House.

Dec 23 – 30

€ 154 per night

Guest favorite

Apartment in Murphysboro

4.96 out of 5 average rating, 23 reviews

The Windbreak

Jul 7 – 14

€ 84 per night

Guest favorite

Cabin in Murphysboro

4.94 out of 5 average rating, 83 reviews

Lakefront Woodland Wonderland—Shawnee NF—ILOzarks

Aug 11 – 18

€ 199 per night

Guest favorite

Apartment in Murphysboro

4.96 out of 5 average rating, 28 reviews

2br Private Guest Suite In Town on 4 Acre Estate

Oct 23 – 30

€ 117 per night

Guest favorite

Home in Murphysboro

5.0 out of 5 average rating, 59 reviews

Embers of Murphysboro

Nov 28 – Dec 5

€ 482 per night

Guest favorite

Apartment in Murphysboro

4.83 out of 5 average rating, 24 reviews

Lake front getaway for 2!

Dec 23 – 30

€ 117 per night

Guest favorite

Apartment in Du Quoin

4.95 out of 5 average rating, 95 reviews

30 West..The Den (#2)

Jan 13 – 20

€ 92 per night

Guest favorite

Place to stay in Ava

4.96 out of 5 average rating, 26 reviews

Crazy Joe’s Cabin #2

Jun 8 – 15

€ 111 per night

Show all

Quick stats about vacation rentals in Murphysboro

Total rentals
30 properties
Rentals with dedicated workspaces
10 properties have a dedicated workspace
Pet-friendly rentals
10 properties allow pets
Family-friendly rentals
20 properties are a good fit for families
Total number of reviews
820 reviews
Nightly prices starting at
€ 28 before taxes and fees

Frequently Asked Questions

What are the most popular amenities for House Rentals in Murphysboro?
Enhance your stay in our House Rentals with the most popular amenities: over 10 homes with wifi, over 10 homes with a kitchen, over 10 homes with air conditioning, over 10 homes with free parking, and more. Indulge in the ultimate retreat, tailored to your preferences.
Do house rentals in Murphysboro have free parking?
Absolutely! We offer over 10 house rentals with free parking in Murphysboro. Enjoy a tailored experience with all the comforts you desire.
Are there family-friendly vacation rentals in Murphysboro?
Murphysboro has more than 20 family-friendly stays. Amenities on the property may include high chairs, travel cribs, or strollers.
Are there pet-friendly vacation rentals in Murphysboro?
Four-legged friends are welcome in Murphysboro. Choose from more than 10 vacation rentals for guests traveling with pets.
Do house rentals in Murphysboro have wifi?
Absolutely! We offer over 10 house rentals with wifi in Murphysboro. Enjoy a tailored experience with all the comforts you desire.
Are there vacation rentals with a dedicated workspace in Murphysboro?
Yes! Work meets play with ease at over 10 vacation rentals in Murphysboro featuring dedicated workspaces. Stay connected and productive in your home away from home.
How much does it cost to stay in house rentals in Murphysboro?
Experience the best of Murphysboro with our house rentals, starting at about $30 per day, before taxes and fees. Embrace comfort and style while staying within your budget in your home away from home.
Do house rentals in Murphysboro have air conditioning?
Absolutely! We offer over 10 house rentals with air conditioning in Murphysboro. Enjoy a tailored experience with all the comforts you desire.

Vacation rentals in Murphysboro

Top-rated vacation rentals in Murphysboro

Vacation rentals for every style

Cabins

Hotels

Unique stays

Popular amenities for Murphysboro vacation rentals

Stay near Murphysboro's top sights

Other great vacation rentals in Murphysboro

Home in Murphysboro

Apartment in Murphysboro

Cabin in Murphysboro

Apartment in Murphysboro

Home in Murphysboro

Apartment in Murphysboro

Apartment in Du Quoin

Place to stay in Ava

Quick stats about vacation rentals in Murphysboro

Total rentals

Rentals with dedicated workspaces

Pet-friendly rentals

Family-friendly rentals

Total number of reviews

Nightly prices starting at

Frequently Asked Questions

What are the most popular amenities for House Rentals in Murphysboro?

Do house rentals in Murphysboro have free parking?

Are there family-friendly vacation rentals in Murphysboro?

Are there pet-friendly vacation rentals in Murphysboro?

Do house rentals in Murphysboro have wifi?

Are there vacation rentals with a dedicated workspace in Murphysboro?

How much does it cost to stay in house rentals in Murphysboro?

Do house rentals in Murphysboro have air conditioning?

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