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Vacation rentals in Middlesex County

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Middlesex County

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite
The living area features large windows allowing natural light to illuminate the space. A comfortable gray sofa and a wooden coffee table are placed on a light wood floor. A unique wooden chair and a wall clock complement the exposed brick walls.
Apartment in St. Thomas
4.98 out of 5 average rating, 153 reviews

Luxury Loft Living

Welcome to Luxury Loft Living in historic downtown St. Thomas. This early 1900’s two story studio boasts an impressive renovation featuring 15ft ceilings and beautiful exposed brick. It’s unique, stylish and modern. Perfect for those travelling for work or study. Conveniently located within walking distance of shops, dining and the public library. 12 minute drive to the 401 as well as the highly sought after Port Stanley beach. Controlled entry and free parking. Come & experience loft luxury!

Top guest favorite
A modern studio apartment is presented, showcasing a spacious sitting area with a large flat-screen television mounted above a contemporary electric fireplace. The open kitchen features updated appliances and a dining table for four, complemented by warm lighting and wood accents.
Guest suite in London
4.97 out of 5 average rating, 175 reviews

Modern and private guest suite

We've recently renovated our basement to create a stylish, modern, cozy and quiet guest suite. There is a side entrance that opens directly onto stairs taking you down to the unit. It has a locking metal exterior door for sound-proofing and security. The unit is a bright studio apartment with three large windows, a full kitchen, sitting area with tv and fireplace, dining table, queen-sized bed, walk-in closet and your own private bathroom with a five-foot shower. With extensive sound-proofing!

Guest favorite
Guesthouse in Ilderton
4.92 out of 5 average rating, 110 reviews

Timberwalk Guesthouse

Welcome to an amazing winter experience in our cozy guesthouse. Soak in the hot tub, watch a movie in the private guesthouse in front of the fireplace and turn on the diffuser to create the most relaxing evening! There are various aromatic oils to choose from. You can also make an outdoor fire in the large firepit. There is plenty of wood on site! Everything you need to unwind, relax and connect with nature! The floor is heated and the fireplace provides additional warmth to the loft bedroom.

Top guest favorite
Apartment in London
4.96 out of 5 average rating, 122 reviews

Modern Guest Suite with Private Entrance

Welcome and enjoy your stay in London's most desired quiet neighborhood. We have a spacious Walkout basement with a private entrance and Lockbox for self check-in and check-out. Minutes away from amenities like Tim Hortons, Bus stop, YMCA, Maisonville Shopping Mall and trails. 10 minutes drive to Western University/Fanshawe College and 15 minutes to London's Downtown or Airport. Need a hot drink, we offer a Keurig coffee maker with complimentary coffee pods, kettle, tea, sugar and sweetener.

Top guest favorite
An open-concept living space features natural wood beams and a striking black accent wall. A round dining table is surrounded by four chairs, with a cozy seating area enhanced by a large beanbag. Decorative plants and stylish lighting fixtures add warmth to the environment.
Home in London
5 out of 5 average rating, 25 reviews

Chic Lake View Loft

Escape to a boutique, barn-style loft on a restored farmhouse with a serene water view. Enjoy a King-size Endy bed with luxe bedding, 55" 4K TV with Netflix, and hi-fi sound system. Induction stovetop, airfryer/microwave, Nespresso, and teas included. Relax in a spa-like bath with soaker tub and premium toiletries. Work comfortably at a sit/stand desk with Herman Miller Aeron chair, or unwind in the sunroom overlooking greenery. Just minutes from the highway—private, peaceful, and convenient.

Guest favorite
A well-lit living area featuring a cozy sofa and a small round table. A wall-mounted TV is visible, along with open shelves displaying decorative items. Windows with blinds allow natural light, while a desk and office chair provide a functional workspace.
Home in London
4.97 out of 5 average rating, 98 reviews

Welcome to your Serene Gateway!

A fully remodeled private basement unit. Your private Haven. Spacious, beautiful and clean studio in a quiet, beautiful, friendly and family oriented environment. minutes away from amenities like Tim Hortons, Bus stop, YMCA, masonville Shopping Mall and trails. 10 minutes drive to Western University, 11 minutes drive to Fanshawe College and 15 minutes drive to London ontario Downtown or Airport Need a hot drink, we offer a Keuring coffee maker with complimentary coffee pods, tea, suga etc

Top guest favorite
Home in London
5 out of 5 average rating, 39 reviews

Basement Apartment Unit

Welcome to this beautiful and spacious basement unit. Has its own private full bathroom with access to laundry. Shared kitchen on main floor upstairs. Wi-Fi included. Parking spot for one vehicle on the driveway included. No parties, smoking, or pets. Located in a very peaceful neighbourhood with a park and trail within a couple minutes walk, shopping plazas, and excellent dining/entertainment options within 5 minutes drive. Please do not hesitate to message for any questions! Thank you!

Top guest favorite
A serene bedroom is presented with a queen bed adorned in nature-themed bedding. A large mirror stands beside the bed, reflecting soft natural light from the window featuring light curtains. A wall art piece depicting a forest landscape enhances the calming ambiance.
Guesthouse in London
4.93 out of 5 average rating, 115 reviews

Charming Guesthouse Nestled Away

Nestled away in the heart of Old East Village in London Ontario. This guesthouse located in the backyard of a beautiful wooded lot is secluded away from the street and neighbors leaves it for a quiet, uninterrupted vacation. Outdoor covered patio, hottub and lounge area available for those sweet summer night hangouts. Minutes away from some of the best entertainment and dining London has to offer! Queen Bed in bedroom. Pullout couch in living room.

Guest favorite
A modern living room features a mix of textures with exposed brick walls and sleek furniture. A comfortable gray sofa is complemented by a pink accent chair. A large flat-screen TV is mounted on a light wood media console, and decorative plants add a touch of greenery.
Apartment in London
4.95 out of 5 average rating, 58 reviews

1min->CoventGardenMarket/DT/Patio/AC/Laundry/WIFI

Welcome to our cozy one bedroom apartment located in the heart of London, Ontario. Perfect for solo travellers, couples, and small groups this apartment offers high speed internet, a fully stocked kitchen, AC, and a great view of the Budweiser Garden. The convenient location makes it a perfect spot for anyone attending shows or events at the Budweiser Garden. Book your stay now and enjoy all that London has to offer!

Top guest favorite
A modern studio space features a spacious bed with crisp linens and decorative pillows. A comfortable armchair sits next to a stylish wooden media console, housing a large television. Natural light fills the room through windows, with contemporary artwork adorning the walls.
Apartment in Strathroy
4.97 out of 5 average rating, 116 reviews

Strathroy Studio “Boutique living at its best!”

Welcome to your boutique-style studio in Strathroy — spotless, stylish, and thoughtfully stocked for a stress-free stay. Enjoy a 65" smart TV, fast Wi-Fi, a well-equipped kitchenette with coffee, tea & snacks, and a spa-clean bathroom with fresh towels. With private entry, easy parking, and cozy touches like slippers and local tips, it’s the perfect spot to unwind, work remotely, or explore the area in comfort.

Top guest favorite
The living area contains a comfortable sofa and two green armchairs, with a wooden coffee table in the center. A television sits atop a white entertainment unit, and large windows provide a view of nature outside. Light curtains create a bright and airy atmosphere.
Apartment in London
4.92 out of 5 average rating, 171 reviews

Riverfront Retreat Near Downtown

Welcome to our inviting 1-bedroom, 1-bathroom apartment retreat near downtown! Featuring a private balcony overlooking the Thames river and a beautiful trail directly behind the house. All amenities, wifi, laundry, and Netflix included. Enjoy the convenience of being near downtown London. 10-15 minute walk to Budweiser Gardens, Downtown, and a 5 minute drive to Western University.

Guest favorite
A comfortable living area features a spacious gray sectional sofa, accompanied by a glass coffee table. A wall-mounted smart TV is visible, and a small kitchenette area is located in the background. The room is brightened by soft lighting and neutral wall colors.
Home in London
4.84 out of 5 average rating, 207 reviews

Vikkyjas Garden

Welcome to your cozy oasis! Nestled in a beautiful basement, our one-bedroom retreat offers a private entrance, a sumptuous Queen Size bed, and unparalleled privacy. Situated near Argyle shopping mall, parks, and eateries, with Fanshawe college just a 7-minute drive away, enjoy the perfect blend of urban convenience and natural tranquility right at your doorstep.

Popular amenities for Middlesex County vacation rentals

  1. Airbnb
  2. Canada
  3. Ontario
  4. Middlesex County