Vacation rentals in Mayo Lake

Lakefront with Million Dollar Views on HYCO Lake

Get away from the stresses of life with this 3-Bedroom lakehouse with large boathouse. Sleeps 10 people in bedrooms and additional spaces on living room on couches. Breathtaking view of the lake and surrounding. Enjoy the water with included floating water mat or explore the area with our 2 kayaks and 2 paddle boards. Home features 3 bedrooms, 2 full baths, spacious full kitchen, washer/dryer, fire pit, 1,000MBs WIFI, YouTube LiveTV, gas grill , whole house standby generator and other amenities.

Mayo Lake Cabin Fun Peaceful Retreat With Firepits

Moonlight Cabin is a modern waterfront home on Mayo Lake. The lake house and nature provides a secluded and peaceful stay while being minutes from shopping, winery, and dining options. This family friendly cabin is both fun and relaxing. Enjoy quiet mornings overlooking the water with a coffee, swim & play in water, spend evenings by the fire pits, and take in the serenity of nature. Indoors, relax with board games, movies, reading, and fast WiFi. Perfect for couples, families, or work escapes.

Kerr Lake Amazing Views, Private Dock, Quiet

Peaceful lakefront retreat: Private dock, table, and new solar-lit umbrella (7/28/25). Amenities include a new gas grill (7/28/25), paddleboard, canoe, kayak, cornhole, hammock, firepit, puzzles, books, and games. Enjoy a large deck with two tables and a screened porch with couch—perfect for morning coffee. The home features 3 bedrooms, a loft, 3 full baths, and a dedicated workspace. Ideal for families, friends, or fishing trips. Driveway fits 5 trucks with trailers; boat launch 2 miles away.

Lakefront | Kayaks| SUPs | Hot Tub | Boat Options

Optional brand new pontoon boat rental, see below for details! Enjoy a spacious 3200+ SF home with one of the best docks and views on the lake! Stunning water view, room for many and everything you need for a romantic weekend or large gathering of family and friends. Be ready to relax on the water - feel free to use the canoe, kayaks, stand-up paddle-boards, and much more! Unobstructed view for over half a mile right in front of the house! Peace and tranquility at its' finest. Close to VIR!

Private Lakefront Paradise - Paddleboards & Kayaks

*Dogs only allowed with approval from owner. Scroll down to read more.* Beautiful 3 bedroom, 3 bath home on Mayo Lake in Roxboro, NC. Incredible views of the lake. You rarely see anyone on our secluded cove. You can swim, fish, paddleboard, kayak or tie up your boat. House is only 5 minutes from the marina and comes with paddleboards and kayaks and has a fire pit. Large, open kitchen, family room/ entertainment room, ping pong table, and jetted tub. Close to hiking, fine dining, and VIR.

Lakefront Oasis-HotTub|Sauna|GameRoom|Kayaks|Dock

At Pointe Mayo Lake, discover a serene, rustic retreat by Mayo Lake. Enjoy amenities like kayaks & canoes, private dock, fishing rods, a cedar barrel sauna, a grill, a hot tub, a game room, and a fire pit. Perfect for avid vacationers, couples, families, groups of professionals, and even your furry friends! We are Pet and Family Friendly! Love what you see but not ready to book? Click the ❤️ "Save" button on the top right to easily find us again and secure your getaway when you're ready!

Water Front Lake House!

Waterfront home on MAYO LAKE. 2 Bd, 1.5 bath fully furnished . Wi-fi, Smart TVs, Alexa, frig, stove washer/dryer, microwave. Queen-size bed, sleeper sofa and bunk bed. Wrap around porch w/ rocking chairs, swing and 2 picnic tables. Large yard for playing, just feet away from the water, and fire pit. Firewood not provided. Lots of fishing, single kayak, 2 person kayak, canoe and 2 paddle boats available. PERFECT FOR ANY SEASON LONG OR SHORT STAY. Located on Mayo Lake in Roxboro, NC

Lake House Hide Away Steps away from the lake

Experience a peaceful lakeside escape with this beautifully maintained and amenity-rich home steps from tranquil Mayo Lake. Whether you're visiting for fishing, hunting or simply to relax in nature, this Airbnb delivers! This 2 bedroom ,1 bath has a King size bed in one room & a queen in the other . The Kitchen is fully stocked & includes a waffle maker & coffee bar !Whether you want to roast s’mores at the fire pit , take a ride on the kayaks or just relax this is the place for you

Mountain cabin feel on Hyco Lake.

Unwind at this hidden jewel tucked in the woods on Hyco Lake. Forget tiny houses, this “Skinny House” boasts two bedrooms, two baths, a spacious open floor plan, cedar ceilings, fully equipped kitchen, gas grill, solo stove, laundry room. Indoor and outdoor living that is large enough for six adults. Floating dock invites you to spend your days on the lake - swimming, fishing, boating, or just soaking in the views. Canoe, Kayaks, Paddle-boards & life vests provided!

Long’s Lakehouse

Relax with the whole family at this peaceful waterfront property. It is a 2 bedroom, 2 bathroom house with one king bed, one queen bed, and a pull out sofa! The kitchen is fully stocked with a coffee pot, utensils, pizza pan, crock pot, skillet, pots , pans, baking sheets, toaster, oven and microwave! Bedrooms and living room have smart tvs. WiFi available! Enjoy the kayaks, lots of fishing, grilling, and fire pit! There is something for here for everyone!

Majestic Lakefront Log Cabin in the NC High Plains

Cozy Log Cabin located on Lake Mayo just above Roxboro, North Carolina on Whispering Wolf Ranch. Easy access to a functional floating dock. Great for fishing, swimming, meditating, or to just enjoy nature. Paddle boards and Kayaks can be rented at nearby Mayo Lake Park. Can be used for a private romantic getaway or family retreat. Less than 5 miles from the events held at Lake Mayo Park. PARTIES OR EVENTS ARE NOT ALLOWED!

Couples Retreat| Beautiful Views | Perfect Getaway

Come and find a place of rest, relaxation, and renewal at Still Waters. Built with care by its owners and nestled along the water's edge, this custom home offers a tranquil setting where guests can unwind and reconnect with nature. Whether you're planning a romantic getaway, a weekend retreat, or simply seeking a break from the pace of everyday life, Still Waters provides the perfect backdrop for a memorable stay.