Apartment vacation rentals in Little Italy

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Top-rated apartment rentals in Little Italy

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Top guest favorite
A charming exterior view of the adobe-style home is surrounded by vibrant gardens filled with various plants and blooming flowers. A patio is shaded by an umbrella, and steps lead to the inviting entrance adorned with archways and decorative tiles.
Apartment in Mission Hills
4.87 out of 5 average rating, 311 reviews

Spacious apartment, old world charm

Our open-space apartment is full of charm and character. From the Spanish-tiled private entry to the footed tub shower, you will experience a unique feeling. Enjoy the nearby vibrant restaurant scene as well as the rooftop deck with its harbor view! The ceilings are low in a couple spots and could be a challenge for folks who are especially tall. My boyfriend is 6'4" and has learned to adapt! It may be something to consider. House noises travel in this old home, so it can be a factor for some.

Guest favorite
A modern studio living area features a comfortable seating arrangement with a sofa, a coffee table, and a wall-mounted TV. Artwork in bold colors adorns the light grey walls. A kitchenette is visible, equipped with a mini fridge, coffee maker, and sink, complemented by a small dining table.
Apartment in Downtown
4.87 out of 5 average rating, 262 reviews

Bright& Clean, Heart of Downtown Studio - Sleeps 4

This bright and modern studio apartment is the essential San Diego home base. The location is RARE and is within walking distance to the hottest neighborhoods in the Downtown area, the Zoo, Balboa Park and is also only a 10 minute drive from the beach. Bright, airy and stocked with all of the essentials, this space is perfect for small groups or work trippers looking to explore Downtown SD by staying in the heart of it. If you're looking to stay in a truly unique Downtown gem, look no further.

Guest favorite
A modern living space features a soft leather sofa adorned with cushions, accompanied by a round coffee table. Large windows allow natural light to fill the area, which includes a dining table in the background. A stylish entertainment unit holds a television and minimal decor.
Apartment in Little Italy
4.88 out of 5 average rating, 122 reviews

Luxe Little Italy 2BR Penthouse w/ Rooftop Balcony

Located right in the heart of Little Italy is this luxe penthouse apartment offering a modern boho-style retreat with a stunning balcony overlooking pizzerias, wine bars, and coffee shops. Ideal for entertaining and lazy days soaking up the sun, the penthouse gives you the perfect inner city oasis filled with natural light where you can relax, unwind, and live like a local. You’ll be only mins from downtown, the Gaslamp Qtr, beaches and only steps from everything Little Italy has to offer.

Top guest favorite
An expansive outdoor patio is showcased, featuring a comfortable sectional sofa with soft cushions and a stylish coffee table. Bi-folding doors connect to a modern kitchen area adorned with sleek cabinetry. The distant view reveals the San Diego coastline under a clear blue sky.
Apartment in Little Italy
4.94 out of 5 average rating, 201 reviews

Calm Luxury Penthouse Getaway With Panoramic Views

Welcome to the most relaxing and luxurious penthouse condo in Little Italy! Featuring 2 expansive balconies with sweeping views, my condo sleeps 4-6 comfortably and is situated right in the heart of San Diego's most desirable neighborhood, Little Italy. Enjoy an area that is rich in exquisite cuisine, boutiques, patio cafés, exciting bars and local breweries. Area amenities nearby feature the famous San Diego Zoo, beautiful Balboa Park, Waterfront Park, the Convention Center and much more!

Guest favorite
A spacious living area features large windows that fill the room with natural light. A plush white sofa and bright red chairs provide seating, while a round coffee table sits centrally on a red carpet. A wall-mounted TV is visible for entertainment.
Apartment in Gaslamp Quarter
4.89 out of 5 average rating, 1,632 reviews

At Mine | Spacious Suite in the Gaslamp Quarter

This unit is a meticulously renovated historical hotel suite, designed by the renowned Italian firm Pininfarina, located in Downtown San Diego. Nestled in the vibrant Gaslamp Quarter, you'll find yourself in the midst of nightlife with an array of restaurants and bars in close proximity. The suite provides private and spacious accommodations catering to both vacationers and business travelers. Its features include a comfortable king-sized bed, a smart TV, central AC, and a mini-fridge

Superhost
A modern living area features a comfortable dark sofa with light throw pillows, complemented by a coffee table and a small dining setup. Large windows allow natural light to fill the space, and a stylish area rug adds warmth to the hardwood floor.
Apartment in Little Italy
4.77 out of 5 average rating, 198 reviews

Spacious Studio in Little Italy with Parking

Ground level unit. Comes with parking in a gated/covered parking garage within the complex. Centrally located in Little Italy. Close to great restaurants and coffee shops and a private balcony for an awesome view for plane watching. Bird Rock Coffee Roasters is located in the apartment complex on the first floor (Kettner Blvd). The Crack Shack and Ballast Point Brewery are right across the street. The Main Street of Little Italy is 2 blocks away and Waterfront Park is about 3 blocks.

Guest favorite
A comfortable living area is presented, featuring a plush brown leather couch and matching chairs. Natural light enters through a window, illuminating a wooden coffee table adorned with a vibrant green plant. A flat-screen TV is positioned beside the seating, with soft lamps providing additional lighting.
Apartment in Little Italy
4.86 out of 5 average rating, 382 reviews

Entire 2Bd in Most Convenient San Diego Location

Amazing, private apartment home is located in the most convenient location in San Diego. Beautiful Bankers Hill is blocks from Little Italy and just down the road from breathtaking museums and outdoor activities at Balboa Park. Spacious 2br/1ba with professional cleaning and management. Your entire, private apartment comes equipped with high-end appliances, renovated finishes and furnishings, and breath taking views of the city skyline and San Diego Harbor surrounding the property.

Top guest favorite
A vibrant plaza scene is displayed with a gentle fountain in the foreground. Small tables and chairs are arranged under canopies, surrounded by diners enjoying the evening ambiance. Strings of lights hang above, and palm trees line the background against a twilight sky.
Apartment in Little Italy
4.95 out of 5 average rating, 205 reviews

Little Italy by the sea-roomy 2bd 2bath

Welcome to Little Italy by the sea. This stylish inviting condo is located in the heart of Little Italy and features gorgeous city views. Enjoy the luxury of 2 bedrooms and 2 separate full bathrooms - no waiting on others! 2 assigned parking spots! Easy access for all ages! This unit is located in a foodie’s paradise! Walk to Crack Shack, Barbusa, Herb And Wood, Kettner exchange, Juniper and Ivy, Born and Raised, Cafe Gratitude, Ironside Fish and Oysters.

Top guest favorite
A tranquil outdoor space features a large tree providing shade over a wooden platform. A serene Buddha statue is situated on the platform, surrounded by vibrant foliage and decorative stones. Stairs lead to the upper apartments, while lush greenery creates a calming atmosphere.
Apartment in Hillcrest
4.96 out of 5 average rating, 505 reviews

Hillcrest #1 Cozy Private Balcony ZenGarden Garage

Heat up the cherry red kettle or complementary coffee and indulge in a morning snack from your private balcony, overlooking the serene Zen garden, and listening to the zen fountain, creating a chilled ambience. Zen Buddha, awaits your exit and every arrival to the property, whether retuning from the eclectic Hillcrest nightlife, or a scenic stroll through Balboa Park, with its many museums, gardens, fountains, restaurant and coffee shops.

Guest favorite
An open living space is highlighted by a large sectional sofa and a round coffee table. The neutral-toned decor includes a colorful area rug. A dining table with two chairs is visible, while the kitchen area features a minimalist design with essential appliances.
Apartment in Little Italy
4.91 out of 5 average rating, 203 reviews

State & Fir (Little Italy Loft, Free Parking)

Ultra Minimal, Sunlit Bi-Level Loft In The Heart Of Little Italy—A Bright, Aesthetic Escape For Slow Mornings And Cozy Evenings. Enjoy Exposed Brick, High Ceilings, Beautiful Art, And An Airy Open Floor Plan. Step Outside To Trendy Cafés, Restaurants, Wine Bars, Farmers Markets, And Waterfront Park. Just Minutes To The Convention Center, Concerts, And The Trolley. Includes One Free On-Site Parking Spot And Free Laundry. Live Like A Local.

Top guest favorite
The kitchen features modern cabinets in deep blue, complemented by white countertops. A stainless steel refrigerator and gas stove are visible, along with a microwave. Natural light streams in through the window, illuminating the space. Two bar stools sit at the kitchen island.
Apartment in University Heights
4.96 out of 5 average rating, 322 reviews

Bright & Airy Craftsman, Free Parking, WasherDryer

This unit is in the heart of University Heights - a charming and walkable San Diego neighborhood filled with restaurants, coffee shops, and boutiques. It is a mere 5 - 15 minute drive to the city’s finest attractions including the San Diego Zoo, Balboa Park, SeaWorld, the Gaslamp (downtown), the convention center, Mission Beach, Hillcrest, Coronado, and more.

Superhost
A spacious studio features a comfortable bed centered in the room. Two armchairs are positioned beside a small side table near a large window, dressed in elegant curtains. Decorative mirrors and artwork adorn the walls, contributing to the inviting atmosphere.
Apartment in Downtown
4.82 out of 5 average rating, 190 reviews

Tranquil Studio Delight near Convention Center

It's more than a standard lodging; it's a distinctive and welcoming refuge meticulously created to leave a lasting mark on your urban retreat. Adorned with fashionable furnishings and thoughtful touches that capture the city's spirit, it promises a memorable sojourn. Unwind in the comfortable reading corner and chart your city escapades.

Popular amenities for Little Italy apartment rentals

When is the best time to visit Little Italy?

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Quick stats about apartment rentals in Little Italy

  • Total vacation rentals

    Explore 180 vacation rentals in Little Italy

  • Nightly prices starting at

    Little Italy vacation rentals start at € 9 per night before taxes and fees

  • Verified guest reviews

    Over 10,130 verified reviews to help you choose

  • Family-friendly vacation rentals

    60 properties offer extra space & kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 60 rentals that welcome pets

  • Vacation rentals with a pool

    40 properties feature pools

  • Rentals with dedicated workspaces

    100 properties have a dedicated workspace

  • Wi-Fi availability

    170 of Little Italy vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Little Italy rentals

  • 4.7 Average rating

    Little Italy stays receive an average rating of 4.7 out of 5 from guests