Vacation rentals in Las Cruces

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Las Cruces

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite

A modern bedroom is featured with a spacious bed adorned in neutral tones. Two framed artworks are displayed above the headboard. Natural light enters through large glass doors that open to a private balcony, showcasing views of the surrounding city.

Apartment in Santa Cruz de la Sierra

4.96 out of 5 average rating, 76 reviews

Cozy Apt with A/C, WiFi, Washer, Kitchen, Pool.

✨ Modern and cozy apartment with comfort and a great location. Enjoy the pool, balcony with view, and Smart TV with Netflix, Disney+ and Tigo Sports to relax after a day in the city. ✔ Fast Wi‑Fi ✔ A/C in living room and bedroom ✔ Equipped kitchen: microwave, coffee maker, blender ✔ Welcome treats: coffee, drinks & snacks ☕🍫 ✔ Washing machine, iron, hair dryer ✔ Pool and barbecue ✔ Private access & 24/7 security 📍 In Equipetrol, near 2nd ring and minutes from downtown, cafés and supermarkets

Guest favorite

A modern living area features a comfortable sofa and armchair, with decorative pillows and plants adding warmth. Large glass doors frame a view of the terrace and expansive pool, allowing natural light to brighten the space, enhancing the connection to the outdoors.

Apartment in Santa Cruz de la Sierra

4.88 out of 5 average rating, 58 reviews

Mar Adentro 1st row SANTA CRUZ

Front row apartment with ocean views on the ground floor. You walk just a few steps and you will be enjoying one of the largest pools in Latin America. Live a Caribbean dream in the heart of Santa Cruz. This 1 bedroom apartment invites you to enjoy comfortably with its spacious living room, spacious patio and private barbecue with all the luxury you deserve. Be captivated by the majestic beach with crystal clear water in the most beautiful and best located space of the condominium.

Top guest favorite

Green Tower, one of the tallest buildings in Bolivia, showcases modern architecture with its glass facade reflecting the surrounding cityscape. The image captures the building's contemporary design, set against a backdrop of Santa Cruz, featuring both urban and natural elements.

Apartment in Santa Cruz de la Sierra

5 out of 5 average rating, 23 reviews

Green Tower - 26th Floor Spectacular Views

Enjoy your stay in the highest Airbnb in Santa Cruz, and in the best building in the city. In the facilities you can enjoy a pool, steam sauna, spectacular views from the 26th floor to the beautiful Manzana 40 building, the nature of the ecological cordon and the urubo. A few meters away Restaurants, supermarkets, mall, business center, banks, spa. In the same building a few steps away are the tallest and most beautiful restaurants in Santa Cruz, Cielo skay bar and Jardin de Asia

Top guest favorite

Apartment in Santa Cruz de la Sierra

5 out of 5 average rating, 6 reviews

GREEN TOWER SC Luxury Apartment 22nd Floor

Luxury suite in Green Tower – Santa Cruz 22nd Floor. Live in the tallest and most exclusive building in the city, on the 22nd floor, with panoramic views of Manzana 40, the ecological cordon and the Urubó. Enjoy upscale gastronomy in the same building, in Gardens of Asia, Caudilla, and the stunning Sky bar, it also boasts luxurious common areas such as pool, sauna, churrasqueras and the Sport Motion gym. A new apartment! Furnished with high-end pieces, including a large sofa bed.

Guest favorite

Condo

5 out of 5 average rating, 5 reviews

The Jewel of Equipetrol

Welcome to our 2 bedroom 3 bathrooms apartment, recently renovated, located in the heart of Equipetrol in the new Sky Condominium. The flat offers two spacious rooms, one of which can be used as an office. Each room has its own bathroom, and there's additionally a guest toilet. Moreover, an elegant American kitchen welcomes you to the home. The bright living room receives a lot of natural light and has a Smart-TV. The flat has two balconies with a beautiful view to the city.

Guest favorite

A contemporary entryway featuring sleek, metallic walls and smooth marble flooring. A minimalist reception desk with soft ambient lighting displays the name 'NUU.' A large potted plant adds a touch of greenery, while well-placed lighting creates a bright atmosphere.

Apartment in Santa Cruz de la Sierra

4.91 out of 5 average rating, 35 reviews

apartment with an excellent view

Apartment located in the Equipetrol area. Located on the 13th floor, you'll enjoy stunning views in a comfortable and elegant atmosphere. This apartment has two bedrooms and two bathrooms, ideal for families or groups. It's fully equipped to make you feel at home. Among the building's amenities, you will find a cinema, a swimming pool, a barbecue area, an equipped gym, a playground, and parking for visitors. Easy access to restaurants, shops, and attractions.

Top guest favorite

An outdoor terrace features sleek wooden decking, complemented by low seating arrangements and lush greenery. A tranquil water feature runs along one side, reflecting the surrounding cityscape. Modern buildings rise in the background under a clear, blue sky.

Apartment in Santa Cruz de la Sierra

5 out of 5 average rating, 32 reviews

Elegante departamento familiar en Equipetrol

Have fun with the family in this new, central, and stylish accommodation. Beautiful and modern apartment located in the best area of Santa Cruz. Just a few steps away from the city's best restaurants, pharmacies, supermarkets, cafes, nightclubs, and shopping malls. Ideal for families, a group of friends, or two couples. You can have all the comforts of a luxury apartment for a cozy and pleasant stay. The building's common areas are a dream!

Guest favorite

A tranquil studio space features a spacious bed dressed with light linens and decorative pillows. A cozy seating area includes a dark grey sofa and a round wooden coffee table. Natural light streams through a large window draped with light curtains, highlighting a wall accentuated with soft textures.

Condo in Santa Cruz de la Sierra

4.88 out of 5 average rating, 219 reviews

Quiet Monoenvironment in Equipetrol

Enjoy the simplicity of this quiet studio in the heart of Equipetrol, where you can be close to restaurants, supermarkets, squares, churches, the business center if you come for work in the same way. In your leisure time, the studio has Wify, TV, Netflix, kitchen, microwave, oven, refrigerator and everything you need to be comfortable inside the building, since in the social areas you can enjoy the pool, churrasqueras, game room and coWork

Guest favorite

A comfortable sleeping area features a spacious bed adorned with soft pillows and a decorative throw. Warm bedside lamps illuminate the space, while large windows offer views of the surrounding cityscape and allow natural light to brighten the room.

Apartment in Santa Cruz de la Sierra

4.98 out of 5 average rating, 106 reviews

13° SmartLife - Luxury Equipetrol

Welcome to your sanctuary of sophistication and elegance at the top. This exceptionally cozy and stylish studio on the 13th floor invites you to experience luxury and comfort at their finest. Ready to experience the perfect combination of sophistication, comfort, and technology? Don't miss out on this unique opportunity. Book your stay at "13° SmartLife" and be seduced by the charm of this incomparable space! Your urban retreat awaits.

Guest favorite

A compact living area features a dark blue sofa facing a flat-screen TV mounted on the wall. A modern dining table with two chairs is positioned near the kitchen, which includes sleek cabinetry and stainless steel appliances. Natural light brightens the space through a large window.

Apartment in Santa Cruz de la Sierra

4.91 out of 5 average rating, 101 reviews

Hermoso Apartamento 1 dormitorio Equipe

One-bedroom apartment, perfect for your next stay in Santa Cruz de la Sierra! Centrally located a few steps from Equipetrol, the city's commercial, business and social center. The unit has a cozy space that offers all the necessary amenities for a comfortable and memorable stay. It includes a service area, washer and dryer, iron, coffee maker, dishes, bed linens, 2 55” smart TVs with cable, Netflix, and a sofa bed. Reserve now!

Guest favorite

A spacious bedroom features a large bed with a light-colored coverlet, set against a backdrop of expansive glass walls. Natural light filters in, illuminating the room. A woven area rug adds texture, while views of the surrounding greenery provide a sense of connection to nature.

Farm stay in La Guardia/Santa Cruz/Bolivia

4.89 out of 5 average rating, 57 reviews

Casiopea Eco-lodge

Relax and enjoy a moment with nature, 10 minutes from the municipality of La Guardia and 3 minutes from the Tranca al Torno entering through Cañada Seca. Equipped kitchen, air conditioning, 2 1/2 person bed with the option to add 1 or 2 extra mattresses; Grill, dining room, refrigerator, electricity, water, Wi-Fi, ample space for walking trails. Fruit trees, easy access with shops nearby for groceries. Owners live on site.

Superhost

A spacious building with a thatched roof sits amidst lush greenery and colorful flowerbeds. A large, turquoise lagoon is visible in the background, with sandy areas and pathways leading toward the water's edge.

Cabin in Provincia de Andrés Ibáñez

4.93 out of 5 average rating, 60 reviews

Sunset cabin on the sea

Cabaña de Sol is located in Santa Cruz de la Sierra, just 9 km from the Gabriel René Moreno Autonomous University, and offers beachfront accommodation, with a restaurant, bar, garden and free Wi-Fi. Free private parking. The vacation home is also available. Activities in the surrounding area include hiking, cycling, and tennis.