Vacation rentals in La Mesilla

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Top-rated vacation rentals in La Mesilla

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite

A spacious dining area features a large wooden table with eight chairs, surrounded by warm terracotta tile flooring. Soft natural light filters through multiple windows, highlighting the exposed wooden beams above. A cozy living space is visible, showcasing comfortable seating and a subtle entertainment setup.

Home in Santa Fe

4.98 out of 5 average rating, 182 reviews

Tres Pastores - Beautiful Tesuque Escape

Welcome to your home away from home! Peaceful, spacious, (2100 sqft) private home on secluded 5 acre compound in beautiful Tesuque. Conveniently located just 9 miles from downtown Santa Fe. This beautiful adobe home has two large bedrooms, two bathrooms, and a fully stocked open concept kitchen. The home exudes Santa Fe charm with vigas throughout, Saltillo tile, functional kiva fireplace, and ample windows for natural lighting. Private outdoor patio and access to breathtaking views from gazebo

Guest favorite

An open living space features high ceilings with exposed wooden beams. A cozy seating area is arranged with a large couch, complemented by a coffee table and colorful rug. Natural light fills the room through multiple windows, enhancing the inviting atmosphere.

Apartment in Chimayo

4.89 out of 5 average rating, 174 reviews

Light Airy Spacious Retreat Between Santa Fe Taos

The Loft is a lovingly restored 300 year old adobe on the 2nd story of Rancho Manzana. Located on the historic Plaza del Cerro, in the world famous rural town of Chimayo. The main level features huge picture windows, soaring ceilings, a bedroom with a private claw foot soaking tub, a den with a double bed, & the sleeping loft with a double bed. There is a fully equipped kitchen, one bathroom with shower. Beautiful views and sunsets, overlooking the apple orchards and red cliffs in the distance.

Top guest favorite

A welcoming living area showcases a light brown leather sofa and a circular wooden coffee table. Large glass doors provide a view of the patio with an outdoor fireplace, allowing natural light to fill the space. A dining table set for four is located nearby.

Home in Santa Fe

4.99 out of 5 average rating, 156 reviews

Happy Ram: Views! Beautiful. Peaceful. Upscale.

Want a unique, stylish, peaceful stay in Santa Fe? Happy Ram is an architect-designed, professionally decorated home on a 6.4-acre estate. Huge views of the Sangre de Cristo mountains from every room. Thick rammed earth walls create incredible quiet. Bedrooms on opposite sides of the home for maximum privacy. Patio with fireplace. Just 5 minutes to hip Tesuque Village, 6 to Four Seasons Resort, 11 to Santa Fe Opera, 14 to Santa Fe Plaza. Make your Santa Fe dream vacation come true! STRO-40172

Guest favorite

A series of images showcases the guest house and farm setting. The large bedroom features a king bed and natural light from a window. The farmhouse kitchen includes wooden cabinets and cooking utensils. The organic garden reveals rows of vegetables, while a chicken interacts with a simple nesting area.

Farm stay in Santa Fe

4.92 out of 5 average rating, 119 reviews

Nambé Farm Stay

Join us on our organic veggie farm, 20 minutes north of Santa Fe and 25 minutes from Los Alamos, in beautiful Nambé. Our guest house is a stand alone casita with a fenced-in yard for your dogs, on our 5 acre working-farm property. The space has a large bedroom with king bed and writing desk, a living room with a comfy leather couch, tv with streaming capacity, a large bathroom with a tub, shower, washer/dryer, and a farmhouse kitchen to cook in. There is WiFi through-out. Pop-up cot available.

Superhost

A glamping dome is nestled within a rugged, natural landscape, surrounded by canyons and desert terrain. The scene captures the dome's unique shape against a backdrop of rolling hills and distant mountains, set under a warm, golden sunset.

Dome in Santa Fe

4.82 out of 5 average rating, 493 reviews

Santa Fe Super Dome

*READ ALL property info BEFORE BOOKING* Stay in the coolest spot in the Santa Fe area. New deck! Glamping dome on 8 private acres of ancient canyons, just south of Santa Fe on Hwy 14. Enjoy 360 degree views of every mountain chain in the area - Sangre de Christos, Jemez, Sandias, Ortiz, Manzanos. You even get Mt. Taylor, silhoutted in exquisite sunsets. This is the ultimate high desert glamping experience. Indoor plumbing, heat, stone shower, king bed. Personal Chef services available.

Top guest favorite

An inviting living area features high ceilings with exposed wooden beams. A white sofa with decorative pillows and a cozy armchair are present, along with a rustic wooden trunk as a coffee table. Natural light filters through the windows, enhancing the warm tones of the space.

Home in Dixon

5 out of 5 average rating, 297 reviews

Stylish cottage in a beautiful canyon on the river

We welcome guests of all races, faiths, genders, sexual orientations, and countries of origin. Over a bridge and steps from the Embudo River, this stylish, well-equipped cottage is nestled under cottonwood trees in a private canyon facing a stunning rock face. Relax on the deck overlooking the water, and during late spring and early summer, listen to the river as you fall asleep. The quaint village of Dixon (an artist and vineyard, orchard, organic farm community) is just a mile away.

Top guest favorite

A hot tub is situated on a wooden deck, surrounded by tall trees and a clear blue sky. The water's surface reflects the sunlight, creating a serene setting for relaxation amidst a forest backdrop.

Cabin in Jemez Springs

4.94 out of 5 average rating, 209 reviews

Cozy Forest Escape with Private Hot Tub

Escape to a Peaceful Forest Retreat Nestled on a 1.5-acre wooded lot, this relaxing cabin offers the perfect retreat for nature lovers and adventure seekers. Located adjacent to the Valles Caldera National Preserve, our property boasts: - Relaxing Hot Tub: Unwind among the pines - Wildlife watching opportunities - Short drive to Fenton Lake for top-notch fishing - Modern comforts for a peaceful stay - Proximity to outdoor activities for all seasons: hiking, biking, fishing, and skiing

Guest favorite

The exterior of a cozy two-story home is shown, featuring a warm earth-toned facade and a metal roof. The surrounding landscape includes rolling hills and sparse vegetation, with trees displaying autumn colors. A fenced area is visible, enhancing the sense of privacy.

Home in Abiquiu

4.81 out of 5 average rating, 542 reviews

Raven House

This cozy 2-story home sits on 10 acres in the Chama River Valley. A seasonal creek runs along edge of land with amazing mountain views. Ideal for a single artist, couple or small family. Hiking + hot springs nearby, including Ghost Ranch, Poshuouingue ruins & Ojo Caliente Springs! Most pets are welcome (for a pet fee). It's helpful to check in on it, however, due to our contained pups further back on the land. Open to longer stays at discounted price. Write about either to discuss!

Top guest favorite

Cabin in Jemez Springs

4.98 out of 5 average rating, 121 reviews

River Oasis | Hot Springs Nearby

Nestled at the base of a majestic mountain, Casa del Rio offers sweeping views of the mesa and river, with the Jemez River flowing right through the property. Modern amenities meet natural beauty—enjoy sunsets from the deck, s’mores by the riverside firepit, and drift off to the soothing sounds of the water. Just five minutes from hot springs and scenic hikes, and only an hour from Santa Fe or Albuquerque, it’s the perfect place to relax, explore, and make unforgettable memories.

Guest favorite

Camper/RV in Española

4.94 out of 5 average rating, 204 reviews

Charming Camper near Santa Fe

Newly renovated modern & spacious camper is located on a private gated 3.5 acre property in historic and beautiful Española River Valley, surrounded by 200 year old cottonwood trees and a running acequia. Located only 27 miles from Santa Fe, 24 miles from Abiquiu, 43 miles from Taos, 21 miles from Los Alamos, 12 miles from Chimayo, and 90 miles from Albuquerque, this relaxing & well-equipped camper provides the perfect getaway and home-base for your stay in Northern New Mexico.

Guest favorite

A living area showcases clay tile flooring with an area rug, featuring a comfortable sofa and a glass coffee table. A fireplace creates a focal point, while soft natural light filters through nearby windows. Rustic wood beams add character to the ceiling.

Home in Santa Fe

4.88 out of 5 average rating, 224 reviews

Casa Encantada, Charming Northern New Mexico Adobe

Welcome to Casa Encantada! This charming historic adobe casa is the perfect getaway for those seeking an enchanting break from the bustle of city living. Nestled in the country, 20 miles north of downtown Santa Fe in the historic village of Nambe, this home is ideally situated for excursions to the many beautiful sites Northern New Mexico has to offer. Make Casa Encantada your base camp as you explore Santa Fe and beyond, then come home to a unique and comforting retreat.

Top guest favorite

The entrance of a rustic casita is framed by a tree, featuring a shaded porch with a small table and two chairs. A potted plant adds a touch of greenery. The door is flanked by wall sconces, and a welcoming bell hangs above.

Guesthouse in Santa Fe

4.97 out of 5 average rating, 672 reviews

Beautiful View

Nambé, New Mexico in Santa Fe County quiet rural setting. It is located 20 minutes from Historic Santa Fe, surrounded by Ancient Anasazi hiking trails and ruins. On the High Road to Taos. Enjoy the peace of the country. Safe and friendly. Romantic, comfortable ,within a private compound. All the amenities of home. Star filled nights, quaint, beautiful accommodations and a charming shared garden to relax and enjoy the beauty of the view of the Sangre de Cristo Mountains.