Vacation rentals in La Mesilla

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Top-rated vacation rentals in La Mesilla

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Guest favorite

Guesthouse in Velarde

4.95 out of 5 average rating, 288 reviews

Casita del Bosque

Enjoy the quiet of an old adobe casita in a traditional Northern New Mexico village, only a stone’s throw away from a multitude of attractions and activities. Explore our beautiful canyons, rivers, mountains and unique communities in every direction from Lyden. Experience modern-day Pueblo communities, ancient petroglyph sites, scenic drives, National Monuments, hiking/biking trails, birding hotspots, Georgia O’Keefe’s home, mineral springs and local restaurants. More in “Show Host’s Guidebook”!

Aug 26 – Sep 2

€ 133 per night

Guest favorite

Home in Santa Fe

4.94 out of 5 average rating, 110 reviews

Hacienda Cielo de Nambe, Premiere Getaway Location

Unwind in the privacy & beauty of a historic adobe that was lovingly renovated in 2017. Nambe is known for its graceful private homes & is 20 min north of Santa Fe, an easy drive. At the Hacienda, adventures are just out your front door: Bandelier, Nambe Falls, Abiquiu, the Pueblos, just to name a few. Ancient cottonwoods surround the adobe, and the night sky is filled with stars. Please visit & make yourself at home, & create some special memories of your own here in the Land of Enchantment.

Sep 3 – 10

€ 137 per night

Guest favorite

Home in Santa Fe

4.95 out of 5 average rating, 128 reviews

Casita De Nambe

Our cozy 1 bedroom, 1 bathroom home can accommodate 4 guests, and is perfect for an amazing adventure in beautiful Northern New Mexico. Casita De Nambe is located in the heart of Nambe and comes fully equipped for both long or short term stays. Guests are provided with a fully equipped kitchen, stove heater, washer, dryer, WIFI and a smart TV compatible with Netflix & Hulu. The patio is equipped with a grill and a fire pit for outdoor activities as well as a fully gated yard, perfect for pets!

Dec 11 – 18

€ 127 per night

Guest favorite

Guesthouse in Chimayo

4.93 out of 5 average rating, 122 reviews

Private Retreat with Stunning Views:West

Experience the splendor of the New Mexico countryside during your stay in our beautiful adobe casita. Located on a historic property, 35 minutes North of Santa Fe, in the village of Chimayo. The casita features hand plastered mud walls, soaring ceilings, luxury linens, large picture windows & private decks, in-room coffee maker, small fridge & microwave. Start your day with coffee next to the bubbling pond and end your adventures with a cocktail, taking in an epic sunset in the apple orchard.

Jan 18 – 25

€ 90 per night

Guest favorite

Yurt in Abiquiu

4.91 out of 5 average rating, 469 reviews

Yurt Overlooking the Chama River in Abiquiu

T R A N Q U I L O A tranquil and rustic experience secluded yet easily accessible on a hillside below the stunning Cerrito Blanco in Abiquiu. This large, 24-foot yurt makes the perfect weekend or week-long getaway for a couple or family looking for a unique experience. Sip your coffee (an organic medium roast is provided) on the deck, practice yoga, meditate, read/write, gaze up at the Milky Way, bird watch and take in the beauty of the Chama River Valley, right in the heart of Tewa country!

Sep 18 – 25

€ 121 per night

Guest favorite

Cottage in Los Alamos

4.99 out of 5 average rating, 281 reviews

Los Alamos Casita de Cielo

Our private-entry casita is nestled in the pines, boasts a canyon view, and is only a 5 minute drive to LANL, the Fuller Art Lodge, and the historic district. You’ll enjoy a luxurious queen bed, spa-like bath, and fully equipped kitchenette (stocked with treats!). Clerestory windows keep the space light and bright. Set back on the lot with a private patio and driveway. Easy access to Bandelier, Pajarito Ski Mountain, and downtown via shuttle or car. Let our casita be your home away from home!

Jan 1 – 8

€ 106 per night

Guest favorite

Farm stay in La Puebla

4.92 out of 5 average rating, 100 reviews

Country Casita near Santa Fe, Los Alamos & Taos

Centrally located + easily accessible with a world-apart feel on 21 acres of lush irrigated land. Rural + urban delights close by. 4 mi. to Espanola 25 mi. to Santa Fe + Los Alamos 45 mi. to Taos Work remotely w/ hi-speed internet + enjoy play time in beautiful northern New Mexico. Private patio, full kitchen, comfortable furnishings, streamside escape on the property + gorgeous hiking up the street. Restaurants, galleries, hiking, biking, fishing, skiing, golf, opera, pueblos + hot springs.

Feb 6 – 13

€ 148 per night

Guest favorite

Place to stay in Española

4.97 out of 5 average rating, 106 reviews

The Barn - Tiny Home near Santa Fe & Los Alamos

About 30 minutes from Santa Fe, experience this awesome tiny home themed "The Barn"! The custom bathroom features a stock tank bathtub and sink that you can tell all of your friends and family about! The kitchen is furnished with a refrigerator/freezer, oven/stove, microwave, toaster, coffee pot and more. With a queen bed in the main space and a twin bed in the loft, The Barn can sleep up to 3 people. The home also has a smart TV and Wifi so you can enjoy your stay or catch up on work.

Sep 3 – 10

€ 116 per night

Guest favorite

Guesthouse in Dixon

4.98 out of 5 average rating, 228 reviews

Casita at Bosque Cottage, a Mini Eco-Retreat

Escape to the natural beauty of the Rio Embudo Valley in this private, quiet, straw bale casita on a 6+ acre artist’s homestead in the Sangre de Cristo foothills featuring gardens and earthen buildings. Visit local wineries and the majestic Rio Grande del Norte National Monument, walk down to the river, or get cozy by the fire. Located in the village of Dixon, this is a great jumping off point for ski trips (Taos, Sipapu), snowshoeing, cross country skiing, Ghost Ranch, and Ojo Caliente.

Sep 3 – 10

€ 127 per night

Guest favorite

Guest suite in Los Alamos

4.94 out of 5 average rating, 290 reviews

Guest Room Suite Private Entrance & Bath

10 minute drive to downtown and central part of Los Alamos National Lab. There is a steep driveway and a set of stairs. Once in the room the bathroom is down a little hallway, maybe 10 feet with 3 steps. The room has a mini refrigerator, Keurig, small microwave, message chair, TV with Prime and Netflix. There are drinks, snacks, pods for coffee, tea. Each night stand has an outlet with plugs for phone and laptop. The bath has towels, wash cloths, robes, soap, shampoo, conditioner.

Jul 13 – 20

€ 117 per night

Guest favorite

Guesthouse in Santa Fe

4.97 out of 5 average rating, 486 reviews

Bonita Vista

Nambé, New Mexico in Santa Fe County quiet rural setting. It is located 20 minutes from Historic Santa Fe, surrounded by Ancient Anasazi hiking trails and ruins. On the High Road to Taos. Enjoy the peace of the country. Safe and friendly. Romantic, comfortable ,within a private compound. All the amenities of home. Star filled nights, quaint, beautiful accommodations and a charming shared garden to relax and enjoy the beauty of the view of the Sangre de Cristo Mountains.

Mar 2 – 9

€ 120 per night

Guest favorite

Guest suite in Santa Fe

4.98 out of 5 average rating, 168 reviews

Northern Santa Fe County Retreat

We are situated just 30 minutes north of downtown Santa Fe, with views of both the Sangre de Cristos and the Jemez Mountain ranges. There are walking trails all around, and our property (5 acres) borders the Pojoaque River. It is a quiet and peaceful setting, wonderful for enjoying the majesty of northern New Mexico. We are convenient to Los Alamos, Bandelier National Park, the Santa Fe Opera, Chimayo, Taos, Georgia O'Keeffe's Ghost Ranch and Abiquiu.

May 15 – 22

€ 115 per night