Vacation rentals in La Mesilla

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Top-rated vacation rentals in La Mesilla

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite

A welcoming living area showcases a light brown leather sofa and a circular wooden coffee table. Large glass doors provide a view of the patio with an outdoor fireplace, allowing natural light to fill the space. A dining table set for four is located nearby.

Home in Santa Fe

4.98 out of 5 average rating, 110 reviews

Happy Ram: Views! Beautiful. Peaceful. Upscale.

Want a unique, stylish, peaceful stay in Santa Fe? Happy Ram is an architect-designed, professionally decorated home on a 6.4-acre estate. Huge views of the Sangre de Cristo mountains from every room. Thick rammed earth walls create incredible quiet. Bedrooms on opposite sides of the home for maximum privacy. Patio with fireplace. Just 5 minutes to hip Tesuque Village, 6 to Four Seasons Resort, 11 to Santa Fe Opera, 14 to Santa Fe Plaza. Make your Santa Fe dream vacation come true! STRO-40172

Superhost

A light-filled living area features a modern television unit and a stylish coffee table on a plush, turquoise area rug. A tall plant adds a touch of greenery, while the ceiling fan enhances air circulation in the airy space with vaulted ceilings.

Guesthouse in Santa Fe

4.8 out of 5 average rating, 114 reviews

Desert Hideaway - Private Casita Suite

Brand new shower!! Experience the ultimate desert escape at our guest suite, nestled amidst majestic mountains. This charming oasis offers a serene retreat with a queen bed, full kitchen, bath, and dining room. Embrace the tranquility of the desert landscape as you relax in the cozy suite & savor panoramic mountain views. Immerse yourself in nature's beauty embarking on thrilling adventures. Discover the perfect balance between comfort & breathtaking surroundings in this idyllic desert haven.

Guest favorite

A charming adobe casita is nestled among lush greenery, surrounded by trees and vibrant outdoor space. A small seating area is visible in the foreground, complemented by gently swaying grass. The structure features a metal roof, blending naturally into the serene countryside setting.

Guesthouse in Chimayo

4.83 out of 5 average rating, 164 reviews

Private Retreat in Beautiful Country Setting: East

Experience the splendor of the New Mexico countryside during your stay in our beautiful adobe casita. Located on a historic property, 35 minutes North of Santa Fe, in the village of Chimayo. The casita features hand plastered mud walls, soaring ceilings, luxury linens, large picture windows & private decks, in-room coffee maker, small fridge & microwave. Start your day with coffee next to the bubbling pond and end your adventures with a cocktail, taking in an epic sunset in the apple orchard.

Top guest favorite

The bedroom features a spacious bed adorned with neutral linens and decorative pillows. Natural light enters through a window dressed in light fabric. Two wooden doors, mirrored in design, are positioned against the warm-toned walls, complemented by a woven basket stand nearby.

Home in Santa Fe

4.95 out of 5 average rating, 201 reviews

Casita De Nambe

Our cozy 1 bedroom, 1 bathroom home can accommodate 4 guests, and is perfect for an amazing adventure in beautiful Northern New Mexico. Casita De Nambe is located in the heart of Nambe and comes fully equipped for both long or short term stays. Guests are provided with a fully equipped kitchen, stove heater, washer, dryer, WIFI and a smart TV compatible with Netflix & Hulu. The patio is equipped with a grill and a fire pit for outdoor activities as well as a fully gated yard, perfect for pets!

Guest favorite

A series of images showcases the guest house and farm setting. The large bedroom features a king bed and natural light from a window. The farmhouse kitchen includes wooden cabinets and cooking utensils. The organic garden reveals rows of vegetables, while a chicken interacts with a simple nesting area.

Farm stay in Santa Fe

4.94 out of 5 average rating, 109 reviews

Nambé Farm Stay

Join us on our organic veggie farm, 20 minutes north of Santa Fe and 25 minutes from Los Alamos, in beautiful Nambé. Our guest house is a stand alone casita with a fenced-in yard for your dogs, on our 5 acre working-farm property. The space has a large bedroom with king bed and writing desk, a living room with a comfy leather couch, tv with streaming capacity, a large bathroom with a tub, shower, washer/dryer, and a farmhouse kitchen to cook in. There is WiFi through-out. Pop-up cot available.

Top guest favorite

A bright bedroom features a queen bed adorned with a colorful patterned quilt and several decorative pillows. An antique dresser stands beside the bed, and a lamp is positioned on the nightstand. Natural light filters through a window, illuminating the space.

Cottage in Los Alamos

4.99 out of 5 average rating, 314 reviews

Los Alamos Casita de Cielo (Little House of Heaven)

Our private-entry casita is nestled in the pines, boasts a canyon view, and is only a 5 minute drive to LANL, the Fuller Art Lodge, and the historic district. You’ll enjoy a luxurious queen bed, spa-like bath, and fully equipped kitchenette (stocked with treats!). Clerestory windows keep the space light and bright. Set back on the lot with a private patio and driveway. Easy access to Bandelier, Pajarito Ski Mountain, and downtown via shuttle or car. Let our casita be your home away from home!

Guest favorite

The spacious studio features traditional adobe architecture with exposed wooden beams. A colorful woven blanket adorns the seating area, complemented by wooden furniture. A vintage lamp and decorative pieces add character. A cozy sleeping area is visible, along with natural light filtering through the window.

Guest suite in Santa Fe

4.85 out of 5 average rating, 536 reviews

The Family Casita Santa Fe/ Pojoaque

The Family Casita is the guest wing to a family home with a private separate entrance. This is a large elegant adobe with thick walls that keep it cool in the summer and provide old world charm. A very spacious 900 square foot studio space, it has two original fireplaces, one in the eat-in kitchen, and one in the main room. There is a beautiful hand painted king sized bed and a Euro Lounger (that converts to a double bed), separated by a privacy wall. Dogs welcome. Sorry can't accept cats.

Superhost

A branch of an apple tree is depicted, bearing several ripe apples in shades of red and green. Lush green leaves surround the fruit, creating a vibrant natural scene against a clear blue sky.

Guest suite in Los Alamos

4.77 out of 5 average rating, 155 reviews

Mesa Suite Los Alamos (no cleaning fee, no chores)

Welcome to New Mexico! Located on the Pajarito Plateau, the Mesa Suite is your next private getaway! Tucked away in a quiet Los Alamos neighborhood, we offer a personal courtyard and entry, walk in shower, kitchenette, and plenty of wildlife. Nearby hiking trails have scenic views of the Sangre De Cristo and Jemez mountains. We are also a short drive from Bandelier National Monument, Valles Caldera, and Santa Fe Forest. Abiquiu, Taos, Santa Fe, and Albuquerque are just an hour or two away.

Guest favorite

A vibrant red tiny home features a modern metal roof and large glass doors for natural light. Windows on either side provide views of the surrounding landscape, while low-maintenance landscaping with gravel and small plants emphasizes the home’s rustic charm.

Tiny home in Española

4.96 out of 5 average rating, 175 reviews

The Barn - Tiny Home near Santa Fe & Los Alamos

About 30 minutes from Santa Fe, experience this awesome tiny home themed "The Barn"! The custom bathroom features a stock tank bathtub and sink that you can tell all of your friends and family about! The kitchen is furnished with a refrigerator/freezer, oven/stove, microwave, toaster, coffee pot and more. With a queen bed in the main space and a twin bed in the loft, The Barn can sleep up to 3 people. The home also has a smart TV and Wifi so you can enjoy your stay or catch up on work.

Guest favorite

A two-story home is set against a dramatic sky colored in warm oranges and soft blues. Solar panels are positioned at the foreground, while juniper trees are visible nearby, contributing to the natural landscape of the Chama River Valley.

Home in Abiquiu

4.82 out of 5 average rating, 387 reviews

Hawk House

This cozy 2-story home sits on 10 acres in the Chama River Valley, with views of Cerro Pedernal and the mountains. Rustic, cozy, with all basic amenities. Ideal for the solo artist or couple. Hiking + hot springs nearby, including Ghost Ranch, Poshuouingue ruins & Ojo Caliente Springs! Most pets are welcome (for a pet fee). It's helpful to check in on it, however, due to our contained pups further back on the land. Open to longer stays at discounted price. Write about either to discuss!

Guest favorite

An entrance to the property is framed by adobe walls with a decorative wooden arch and a carved detail. A path, lined with various plants and flowers, leads towards a set of red stairs surrounded by greenery and shade from the trees.

Apartment in Santa Fe

4.89 out of 5 average rating, 207 reviews

Studio in Santa Fe

Located 7 miles north of Santa Fe Plaza, this country retreat, is in the Village of Tesuque, one mile from Tesuque Village Market, El Nido Restaurant and Glenn Greene Galleries, five miles to the Santa Fe Opera, and 7 miles to the Santa Fe Plaza. Enjoy your own studio apartment with outdoor patio, private parking , in a peaceful country setting. Tesuque is central to many New Mexico experiences - visit nearby pueblos, state parks and monuments, casinos, rafting and hiking trails.

Guest favorite

The interior of the camper features a modern design with a spacious island in the center. Soft lighting is provided by decorative hanging lamps. A cozy seating area with a leather couch and two chairs is visible, complemented by natural light from large windows.

Camper/RV in Española

4.93 out of 5 average rating, 164 reviews

Charming Camper near Santa Fe

Newly renovated modern & spacious camper is located on a private gated 3.5 acre property in historic and beautiful Española River Valley, surrounded by 200 year old cottonwood trees and a running acequia. Located only 27 miles from Santa Fe, 24 miles from Abiquiu, 43 miles from Taos, 21 miles from Los Alamos, 12 miles from Chimayo, and 90 miles from Albuquerque, this relaxing & well-equipped camper provides the perfect getaway and home-base for your stay in Northern New Mexico.