Vacation rentals in La Mesilla

Incredible Northern New Mexico Experience Awaits

Enjoy amazing vistas while you relax after a day hike, biking or rafting in the Rio Grande del Norte National Monument, or long day skiing. You'll love the memorable experience gained from this elegant adobe home. Prepare that savory dinner w/ amigos in the gourmet kitchen or enjoy a book during a soothing bath. The home kid friendly and centrally located w/ privacy you’ll cherish. Casa El Guiqueno provides the northern NM experience your looking for at a price that won’t break the bank.

River Oasis | Hot Springs Nearby

Nestled at the base of a majestic mountain, Casa del Rio offers sweeping views of the mesa and river, with the Jemez River flowing right through the property. Modern amenities meet natural beauty—enjoy sunsets from the deck, s’mores by the riverside firepit, and drift off to the soothing sounds of the water. Just five minutes from hot springs and scenic hikes, and only an hour from Santa Fe or Albuquerque, it’s the perfect place to relax, explore, and make unforgettable memories.

Charming Camper near Santa Fe

Newly renovated modern & spacious camper is located on a private gated 3.5 acre property in historic and beautiful Española River Valley, surrounded by 200 year old cottonwood trees and a running acequia. Located only 27 miles from Santa Fe, 24 miles from Abiquiu, 43 miles from Taos, 21 miles from Los Alamos, 12 miles from Chimayo, and 90 miles from Albuquerque, this relaxing & well-equipped camper provides the perfect getaway and home-base for your stay in Northern New Mexico.

Bonita Vista

Nambé, New Mexico in Santa Fe County quiet rural setting. It is located 20 minutes from Historic Santa Fe, surrounded by Ancient Anasazi hiking trails and ruins. On the High Road to Taos. Enjoy the peace of the country. Safe and friendly. Romantic, comfortable ,within a private compound. All the amenities of home. Star filled nights, quaint, beautiful accommodations and a charming shared garden to relax and enjoy the beauty of the view of the Sangre de Cristo Mountains.

Centrally Located Southwest Oasis-Sage Casita

Come soak up the sun and unwind in the Southwest. Sage Casita is peaceful, romantic and has lots of amenities. This casita is less than 30 minutes away from Santa Fe and Los Alamos. As well as less than 15 minutes from Espanola. Besides being centrally located, the casita is thoughtfully furnished making it the perfect place to stay in New Mexico. So come, reconnect with the wide open spaces of the Southwest and enjoy the taste of a peaceful oasis just outside of Santa Fe.

Modern Dome Home near Santa Fe | Los Alamos | Taos

Escape to this newly renovated 3BR/2BA mountain retreat! Set on a private 1/3 acre near the Rio Grande, enjoy a fenced yard, vast outdoor space, and a cozy wood-fired stove. High-speed WiFi included. Prime location: next to Starbucks/Walmart, 30 mins to Santa Fe, and <1 hour to Taos skiing. Whether you're hiking, skiing, or relaxing, this stylish home offers the perfect blend of modern comfort and Northern NM charm. Book your high-desert stay today!

Infinite Views | Ridgetop Retreat | 2 Hot Tubs

There's nothing quite like this in Santa Fe — a genuine Earthship eco-home on a secluded ridgetop, with two hot tubs and views that stretch to the Jemez Mountains. 🛁 2 hot tubs — indoor jetted spa with waterfall & rooftop infinity tub 🌄 Sweeping views of Santa Fe, the Jemez Mountains & National Forest 🌿 Rare Earthship design with living indoor gardens 🧘 Dedicated spa & yoga retreat 🏡 Spacious 2BR entire earth-home, secluded ridgetop setting

The Cabin - Tiny Home near Santa Fe & Los Alamos

Plan your vacation at this cute little cabin! The kitchen is furnished with a refrigerator/freezer, oven/stove, microwave, toaster, coffee pot and more. There is A/C and heating as well as a smart TV and Wifi so you can have a comfortable, relaxing, and productive stay! On top of all that, we are centrally located between Los Alamos, Santa Fe, Pojoaque and Taos so you can easily visit some of our most amazing tourist spots!

Luxury Desert Casita • Chiminea Nights • Views

Stay in a serene casita surrounded by the inspiring landscapes that shaped Georgia O’Keeffe’s art. Located just south of Ojo Caliente and a short drive from Ghost Ranch, this retreat offers effortless access to the area’s best hiking, hot springs, and high-desert beauty. With Ojo Mineral Springs only 14 miles away and dining within walking distance, it’s the perfect base for couples seeking both exploration and relaxation.

Casita Viernes

A newly built casita in a convenient central location, provides easy access to Santa Fe, Los Alamos, Espanola, Abiquiu and Taos. Close to many special attractions such as Santuario de Chimayo, Puye Cliff dwellings, Bandelier National Monument, Los Alamos, Espanola Valley Fiber Arts Center and much more. We are only a few minutes drive off of route 285 in a quiet neighborhood situated behind the Dreamcatcher movie theater.

Guest House in Espanola

This unique place has a style all its own. It is an adorable adobe casita with its own full bath, King bed, mini fridge, microwave and coffee maker. Located in the beautiful Espanola Valley, just 45 miles away from Taos, 25 miles away from Santa Fe and 17 miles away from Los Alamos.The Casita is located near local restaurants and shopping areas but is hidden in its own private beautiful neighborhood.

Finca del Sol - New Mexican Farm Casa

Beautifully restored 4BR/2.5BA farm casa just outside Santa Fe. Enjoy farm-fresh eggs, seasonal produce, and meet goats, sheep, chickens & ducks. Relax in the TV room, work with Starlink internet, or train in the covered outdoor gym. Picnic beneath old cottonwoods, stargaze by night, and take in stunning views of Ski Santa Fe, the Pojoaque Badlands & Jemez Mountains. Gateway to Northern NM adventures!