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Vacation rentals in Isla Caiman

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Isla Caiman

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite
Guesthouse in El Valle de Antón
4.92 out of 5 average rating, 120 reviews

The Retreat in El Valle - Casita de la Montaña

Welcome to your serene retreat in El Valle, Panama! Nestled amid lush nature, our two-bedroom casitas offer a peaceful escape with breathtaking views, exotic wildlife, and flora. Each casita features two rooms, including a queen bed, choice of king or twin beds, a small fridge, coffee station, Wi-Fi, and large terrace with comfy couch. Enjoy the shared pool, book meditation/ healing sessions, explore world-class hiking. Enjoy next door La Compania restaurants, El Valle’s famous artisan market!

Guest favorite
An open-concept loft is showcased with a high, sloped ceiling and large windows that invite natural light. Comfortable seating is arranged around a glass table, while a dining area and a cozy sleeping space can be seen in the background. Nature views are visible through the windows.
Home in Santa Rita Arriba
4.95 out of 5 average rating, 20 reviews

The Bird's Nest in the Clouds

Escape to the Clouds: A Nature Lover’s Retreat. Welcome to The Bird's Nest, a serene loft in Santa Rita Arriba, Colón, 50 minutes from the city. Perched in the mountains, this open-concept space offers breathtaking views, fresh breezes, and the sounds of nature - rain and birds. Sleep with doors open, no AC. Perfect for nature lovers, not for those needing silence or climate control. Pool with breathtaking view, wifi and modern comforts included. PLEASE READ ENTIRE DESCRIPTION BEFORE BOOKING.

Top guest favorite
A modern living room features a spacious sectional sofa arranged around a circular coffee table. A large wall-mounted TV is centered within elegant wooden cabinetry, while planters holding lush greenery add a touch of nature. Natural light fills the room through large arched windows.
Home in El Valle
4.93 out of 5 average rating, 102 reviews

Casa Coco - Beautiful Mountain Villa With AC

Elegant and modern, our home strikes the perfect balance between luxury and warmth. With ample space to accommodate large groups and families, as well as cozy and inviting for smaller groups. The yard features a covered social area, ideal for relaxing or entertaining. A lush garden adorned with vibrant greenery includes a charming mango tree and mountain peak views. A 5 minute walk to restaurants and the open air market. If you have a group larger than 12- please reach out to us directly.

Superhost
The modern house is set amidst lush greenery, featuring a sleek design with large glass windows. An infinity pool is positioned on a spacious patio that offers unobstructed views of the surrounding hills, creating an inviting outdoor space for relaxation.
Home in Altos del María
4.82 out of 5 average rating, 336 reviews

Modern House with Great Views and Heated Pool

Modern mountain house in Altos del Maria, Panama, a gated comunity at just 1 hour and 30 minutes away from Panama city. The comunity has rivers, bird watching trails, and is only 25 minutes away from the pacific beaches. Its a perfect place to take a break and relax. The house has a modern decor, infinity pool, 2 bedrooms with A/C, wifi, dishwashing machine, washer and dryer and great view of the mountains. Free late checkout is given for rentals checking out on Sundays.

Superhost
Home in Altos del María
4.76 out of 5 average rating, 169 reviews

Villa Acuario

Relaxation is guaranteed in this one-of-a-kind glass house nestled in the lush mountains of Altos del María. Surrounded by nature and designed with floor-to-ceiling glass walls on all sides— as if you’re living inside a crystal ball. With no direct neighbors, panoramic forest views, it is perfect for a family getaway, a quiet reset, or an extended stay. The home offers light-filled interiors during the day and unforgettable stargazing nights from the rooftop.

Superhost
A tranquil dipping pool is framed by lush greenery, featuring white loungers and a large umbrella for shade. The pool area exudes a serene vibe with vibrant bougainvillea in the background, enhancing the inviting outdoor space.
Home in Taboga Island
4.94 out of 5 average rating, 224 reviews

Casa Rosie - Dream Home on Tabogá Island

Casa Rosie is a gorgeous villa on Taboga island with an intimate vibe and spectacular views of the ocean. The perfect place for couples, small groups, and families to unwind and make magical memories! . With great wifi, fully equipped kitchen, 3 inviting bedrooms, and a spacious yet personal feel… Casa Rosie is your home away from home. Included in every stay is free pick up and drop off to the ferry terminal - please let us know the details of your arrival.

Top guest favorite
A covered terrace is highlighted by vibrant orange columns and features hanging wind chimes. Lush green trees frame the view of a mountain in the distance, while sunlight creates patterns on the ground through the railing. A serene outdoor space is presented.
Cabin in Altos del María
4.89 out of 5 average rating, 84 reviews

Enjoy the view of Mount Picacho

Relax as a couple or as a family where tranquility is breathed in the midst of trees. During the winter you will hear the sound of our stream and the birdsong. Enjoy every moment of our privileged view of the majestic Pichacho hill in the comfort of our spacious terrace and balconies. We have several spas a few meters away by car. The most famous and beautiful is the one with the Doncellas waterfalls. You can visit nearby towns such as Manglarito and Filipinas.

Guest favorite
A small pool sits within a wooden deck area, surrounded by lush greenery. Steps lead from the deck to the pool, where a gentle waterfall feature adds a soothing element. Lounge chairs are positioned nearby for relaxation in a tranquil setting.
Guesthouse in Panamá Oeste
4.84 out of 5 average rating, 161 reviews

Mountain cabin with private pool

Enjoy peace and nature in this cozy and equipped cabin, perfect for disconnecting and relaxing. Surrounded by forests and spectacular views, here you can breathe fresh air and gaze at the stars. ✔️ Ideal for couples, families or adventurers. ✔️ Trails, rivers and viewpoints nearby. ✔️ Comfortable and equipped spaces for your comfort. - Sleeps 4 people. - Possibility of having 1 double bed and 2 single beds or 4 single beds. - Discount for two nights or more.

Superhost
The villa's modern exterior is illuminated at night, showcasing a sleek facade with clean lines. Lush landscaping with palm trees frames the entrance. A vehicle is parked in front, highlighting the spacious driveway. The large front steps lead to the welcoming double doors.
Home in Veracruz
4.94 out of 5 average rating, 33 reviews

Luxury beachfront villa!

Discover luxury in our new oceanfront villa in Veracruz Chumical, just 30 minutes from Panama City. With 5 bedrooms, 6 bathrooms, 5 king beds and 2 double cabins, it is ideal for families and friends. Relax in the infinity pool with spectacular views or enjoy the equipped kitchen, spacious living room and barbecue area. Take in the illuminated ships on the rooftop and enjoy a unique experience. Book now and enjoy being the first in our beautiful Villa!

Top guest favorite
A private pool area is framed by lush tropical plants and trees, with lounge chairs situated nearby. The pool’s clear blue water reflects the surrounding greenery and the structure in the background, which includes a covered patio for relaxation.
Home in Distrito Arraijan
4.98 out of 5 average rating, 234 reviews

Tropical Haven with Pickleball/Yoga Platform

Tropical "open-concept" Airbnb, with a private pool and yoga/meditation platform, located in a typical village, 20 minutes outside the hustle of Panama City, Panama - Central America. This modern contemporary tropical home is located in the hills of Caceres on a 5 acre finca full of tropical trees, birds, and a manicured grounds. Outdoor gas and charcoal barbecue off of back patio with vertical herb garden for perfect relaxation retreat.

Top guest favorite
Camper/RV in El Valle de Antón
4.99 out of 5 average rating, 287 reviews

Armadillo Shelter & Garden Valle de Anton

It is a unique and special accommodation that we have designed for you to experience the Anton Valley in a more conscious and natural way. It's a remodeled RV or trailer, to make it cozy>functional and comfortable>tiny house style. The space has a small and complete kitchen, hot water, Wi-Fi, coffee and tea. It is surrounded by a nice garden. With a separate entrance and an area to park the car. Ideal for 1-2 people.

Guest favorite
A covered patio area features a gently swaying hammock, set against a backdrop of a sandy beach and rolling waves. The vibrant colors of the sunset reflect on the water, and grassy patches with scattered rocks complete the serene coastal setting.
Home in Vista Hermosa
4.93 out of 5 average rating, 55 reviews

Quiet Caribbean Coastal Escape

Escape to this quiet Caribbean coastal retreat, where the rhythm of the waves and the sea breeze set the pace of your days. Enjoy slow mornings with coffee on the terrace, afternoons swaying in the hammock, and unforgettable sunsets just steps from the shore. Ocean conditions vary throughout the year, making this the perfect place to unwind, listen to the waves, and embrace the beauty of an authentic Caribbean escape.

Popular amenities for Isla Caiman vacation rentals