
Places to stay near Biomuseo
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Top-rated vacation rentals near Biomuseo
Guests agree: these stays are highly rated for location, cleanliness, and more.

CASA SAEMA -PRESTIGIOUS DUPLEX PENTHOUSE WITH TERRACES
Spectacular duplex penthouse in Panama's Old Town, 265 m² with balconies, private outdoor terraces, an indoor garden living room, a dining room, 3 bedrooms (+ sofa bed in the studio), recently renovated with a loft concept, an exclusive, unique and comfortable design, in the best area of the Old Town, perfect for relaxing and unwinding. It has a kitchen, dishwasher, laundry room with washing machine, shared pool, elevator, 24/7 doorman (the pool is not suitable for children), and a wide variety of entertainment options in the area.
4.88 out of 5 average rating, 150 reviews
In the heart of Casco, remodeled and with parking
Escape and discover the old town in this remodeled, comfortable and central accommodation in the heart of Casco Viejo. Our location is the best, it will make you come back. Close to restaurants, bars, impressive churches, and museums. The property dates back to the 17th century (1756) history and good atmosphere. You can explore the area on foot, fully equipped kitchen, European king bed, you will feel right at home, surrounded by the famous calicanto walls. -A large living room -Fully-equiped kitchen
4.96 out of 5 average rating, 263 reviews
Spacious 6BR House w/ Pool, Gym & King Beds
Enjoy a spacious private home in the heart of Punta Paitilla, one of Panama City’s most central neighborhoods. Perfect for families and groups, the house features 6 bedrooms, 5.5 bathrooms, 9 beds, a private pool, and plenty of space to relax, comfortably accommodating up to 17 guests. Walk to supermarkets, restaurants, and nearby synagogues, or reach Multiplaza and other popular areas of the city within minutes. A comfortable and convenient home base for enjoying Panama City together.
4.98 out of 5 average rating, 120 reviews
The View of Casco: Designer Loft with best Balcony
Sip your morning coffee or evening wine on the balcony, taking in a stunning, panoramic view of the city skyline! Experience the absolute best of Casco Viejo from this elegant, fully remodeled 1-bedroom loft. Nestled inside a beautifully restored 1850 colonial building—featuring historic, original calicanto walls—this stylish space puts the entire city at your doorstep. You are just steps away from world-class dining, vibrant cafes, museums, and Casco's legendary nightlife
4.98 out of 5 average rating, 134 reviews
Stunning Terrace Among Ruins in Casco Viejo
Welcome to your Casco Viejo retreat! This spacious apartment, perfect for up to 8 guests, offers a unique blend of modern comfort and historic charm in Panama City’s most iconic neighborhood. Located in the heart of Casco Viejo. The highlight of this beautiful space is the stunning terrace nestled among historic ruins, where you can relax, enjoy a meal, or simply take in the timeless atmosphere. This is more than a stay – it’s an unforgettable experience.
4.82 out of 5 average rating, 142 reviews
Loft in Casco Antiguo, Joya Colonial
Welcome to a space where history, design and comfort merge in one of Panama's most iconic neighborhoods. This apartment, located in the heart of the Old Town, immerses you in the rich colonial culture and architecture, while offering you all the modern amenities for an unforgettable stay. ✔ Spacious ✔ Classic-modern design ✔ Equipped kitchen ✔ Private balcony ✔ Dreamy master bedroom ✔ High-speed WiFi and Smart TV ✔ An unbeatable location
4.95 out of 5 average rating, 104 reviews
Tropical Haven with Pickleball/Yoga Platform
Tropical "open-concept" Airbnb, with a private pool and yoga/meditation platform, located in a typical village, 20 minutes outside the hustle of Panama City, Panama - Central America. This modern contemporary tropical home is located in the hills of Caceres on a 5 acre finca full of tropical trees, birds, and a manicured grounds. Outdoor gas and charcoal barbecue off of back patio with vertical herb garden for perfect relaxation retreat.
4.98 out of 5 average rating, 234 reviews
Apartment in the Causeway Amador
Forget your worries in this spacious and serene space. Where you can enjoy the views of the Panama Canal and see the boats that pass through it, a space full of amenities with a perfect location, you can walk through the streets of the Causeway, visit the Biodiversity Museum, restaurants of various specialties, amusement park, bike rides etc, everything comes together to make this vacation an unforgettable experience for your whole family
4.75 out of 5 average rating, 121 reviews
Amazing experience 3BR 2BTH Casco Viejo w/Rooftop
Enjoy Panamanian culture from the center of Casco Viejo, where you'll discover colonial architecture, visit the area's best restaurants, nightspots, and rooftops. Quiet and comfortable apartment. Features a living room, dining room, equipped kitchen, work desk, 2 queen beds, 1 twin bed, 2 bathrooms, closets, air conditioning, balcony, barbecue, and outdoor dining area. We offer everything you need to have the best local experience!
4.8 out of 5 average rating, 110 reviews
Loft 3b Old Town Best! It's 150 m2 (492 feet)
Immerse yourself in the historic charm and modern elegance of our 3-bedroom, 150 m2 loft in the heart of the Old Town. With wooden floors that radiate warmth and a modern open-plan kitchen ideal for sharing, this space guarantees a memorable vacation. Located on Avenida A, you'll find yourself just a few steps away from exquisite restaurants, museums, colonial churches, and the Casco's coveted rooftops, making every day an adventure.
4.93 out of 5 average rating, 126 reviews
The best view of the Old Town
Welcome to this charming accommodation located in the heart of Casco Viejo, on the third floor facing one of the most iconic squares in Panama, Plaza Catedral! Thanks to its privileged location, you will enjoy a unique view of the square and the imposing Cathedral Church. Right in this lively square, you will have at your disposal a wide variety of restaurants and shops where you can buy souvenirs of this wonderful trip.
4.92 out of 5 average rating, 131 reviews
2B Loft Studio | Design By Paradox
Private 40 m² loft studio in Santa Ana, about a 5-minute walk from Casco Viejo. Loft Studio sleeps up to 3 guests with a Queen bed on a mezzanine and a sofa bed, plus a full kitchen, private bathroom, air conditioning, hot water, fast WiFi, dining space, and a 1.8 m desk. Enjoy a TV with Roku and host-provided Netflix, Disney+, Max, and Prime. Guests have access to the shared balcony, patio, and paid laundry.
4.89 out of 5 average rating, 360 reviewsPopular amenities for vacation rentals near Biomuseo
Condo rentals with wifi

Modern 1BR in San Francisco/Pool/Gym/Balcony
4.91 out of 5 average rating, 205 reviews
Modern Stay | Prime Location | Pool, Rooftop & Gym
4.98 out of 5 average rating, 108 reviews
Family apartment 3 bedrooms pool wifi free parking
4.87 out of 5 average rating, 116 reviews
Spacious & Centric 3-Bedroom Apartment!
4.89 out of 5 average rating, 190 reviews
City center apt with 2BR/3beds parking and terrace
4.79 out of 5 average rating, 137 reviews
Apartment with balcony in Casco Antiguo
4.86 out of 5 average rating, 103 reviews
Cozy 2 bedroom Apt. in Panama City, Panama
4.95 out of 5 average rating, 145 reviews
Ph Quartier Marbella 18E apt with rooftop pool
4.85 out of 5 average rating, 131 reviewsFamily-friendly house rentals

Central|Confort|surrounded by nature|Wifi|parking
4.84 out of 5 average rating, 118 reviews
3BR Home in Ancon Hill - Urban Oasis
4.9 out of 5 average rating, 117 reviews
AX8 beach house near the city!
4.94 out of 5 average rating, 113 reviews
Spacious Panama House in the 'heart of the city'
4.84 out of 5 average rating, 128 reviews
Private Studio 10 Min from the Airport!
4.94 out of 5 average rating, 444 reviews
3BR Island Retreat with Oceanview Rooftop Pool
4.79 out of 5 average rating, 112 reviews
House for groups · 6 bedrooms/6 bathrooms near the Canal
4.94 out of 5 average rating, 16 reviews
Simple 2-bedroom house near the beach
5.0 out of 5 average rating, 32 reviewsApartment rentals with air conditioning

Studio apartment in the heart of Casco
4.78 out of 5 average rating, 203 reviews
Apartment in Casco Viejo, Panama's Old Quarter
4.94 out of 5 average rating, 220 reviews
LUXURY APT/Ocean View & Rooftop
4.96 out of 5 average rating, 181 reviews
Full apartment in Panama
4.98 out of 5 average rating, 164 reviews
Luxury Mid-Century Apartment In Casco Viejo
4.97 out of 5 average rating, 119 reviews
Beautiful Apt, Best Location 2BR
4.89 out of 5 average rating, 196 reviews
2BR Newly Renovated Amador Causeway Appartment
4.84 out of 5 average rating, 149 reviews
The Sands | Stunning Ocean View
4.63 out of 5 average rating, 8 reviewsOther great vacation rentals near Biomuseo

Casa Vidal - The Only House in Casco Viejo
4.89 out of 5 average rating, 73 reviews
Luxury apt in Panama City 2 Rooms 3 Baths
5.0 out of 5 average rating, 87 reviews
Panama Pacifico P.H. Centriqo: Close to Everything.
5.0 out of 5 average rating, 32 reviews
Private parking & rooftop | Studio Casco Center
5.0 out of 5 average rating, 40 reviews
Casa del Horno | A Piece of Panamanian History
4.93 out of 5 average rating, 73 reviews
Casa Esmeralda Refined 120 m² Duplex in Casco Viejo
4.94 out of 5 average rating, 36 reviews
Panoramic Casco Viejo Lookout in The Sands
4.95 out of 5 average rating, 76 reviews
GreatCanal-Front Luxury 3BR | City & Golf View 401
5.0 out of 5 average rating, 12 reviews




