
Vacation rentals in Panamá Province
Find and book unique accommodations on Airbnb
Top-rated vacation rentals in Panamá Province
Guests agree: these stays are highly rated for location, cleanliness, and more.

Casa Condal - Your Luxury Retreat in Cerro Azul
Birdwatching • Romantic Getaway • Remote Work Escape the city. Breathe pure mountain air. Reconnect with nature. Casa Condal - private, modern, sustainable and regenerative hospitality inside Chagres National Park WiFi 65" Smart TV. Sound Bar Self check-in Private parking Fully equipped kitchen 220mts. private trail Deck-Mirador + FirePit, panoramic view of the mountains and valley King bed + Full size sofa bed BBQ Wheelchair accessible 40 min from Tocumen Airport. 1 hr from Panama city.

CASA SAEMA -PRESTIGIOUS DUPLEX PENTHOUSE WITH TERRACES
Espectacular ático Duplex en Panamá Casco antiguo, de 265 M2 con balcones, terrazas privadas exterior, cuenta con una salón jardín interior, un comedor, 3 hab. (+ sofá cama en studio), recientemente reformado con concepto Loft, diseño exclusivo único y confortable, en la mejor zona del Casco viejo, perfecto para relajarse y desconectar, cocina , lavavajilla, sala con lavadora. piscina compartida, asc, portero 24-7, no se permiten niños que no sepan nadar, gran variedad de ocio en la zona.

The View of Casco: Designer Loft with best Balcony
Sip your morning coffee or evening wine on the balcony, taking in a stunning, panoramic view of the city skyline! Experience the absolute best of Casco Viejo from this elegant, fully remodeled 1-bedroom loft. Nestled inside a beautifully restored 1850 colonial building—featuring historic, original calicanto walls—this stylish space puts the entire city at your doorstep. You are just steps away from world-class dining, vibrant cafes, museums, and Casco's legendary nightlife

Walk to Everything | Luxury Stay in Casco Viej
Wake up overlooking one of the last historic bastions of Casco Viejo, sip your morning cofee on a private balcony, and step directly into Panama City most vibrant and wakable neighboorhood. Surrounded by colonial architecture, charming plazas, and a vibrant culinary scene, this space invites you to experience Panama with style and tranquility. Ideal for those seeking an exclusive, walkable, and characterful environment in one of the city's most iconic areas.

Casco Antiguo Apartment with Balcony & Stone Wall
Elegante apartamento en el corazón de Casco Antiguo. Disfruta de un espacio colonial con paredes de piedra expuesta, iluminación cálida y un encantador balcón con vista a calles vibrantes. Ubicado en Avenida B, a pasos de restaurantes, cafeterías, rooftop bars y lugares históricos. Capacidad para hasta 5 huéspedes. Perfecto para vivir la cultura y energía de Casco Viejo. Debido al ambiente animado del área, puede escucharse ruido nocturno los fines de semana.

The apartment of a legendary Panamanian footballer
Location is everything – just steps away from the city’s best restaurants, bars, stunning churches, and fascinating museums. Explore the historic district on foot while enjoying the comfort of a stylish apartment featuring: • A spectacular balcony with beautiful views • A fully equipped kitchen • 1.5 bathrooms • Cozy beds that make you feel right at home • Surrounded by iconic calicanto stone walls that reflect the charm of Panama’s colonial past.

Private parking & rooftop | Studio Casco Center
This beautiful restored studio from the 1870s blends history with modern design. Enjoy a private rooftop terrace with seating and BBQ, plus private PARKING—ideal after exploring Casco's best restaurants, galleries, and nightlife steps away. ✨ Highlights: - Historic Charm: Original tile floors and exposed colonial stone walls. - Comfort: King bed, living room, and full kitchen. - Amenities: Private rooftop & private PARKING. - Great location

Tropical Haven with Pickleball/Yoga Platform
Tropical "open-concept" Airbnb, with a private pool and yoga/meditation platform, located in a typical village, 20 minutes outside the hustle of Panama City, Panama - Central America. This modern contemporary tropical home is located in the hills of Caceres on a 5 acre finca full of tropical trees, birds, and a manicured grounds. Outdoor gas and charcoal barbecue off of back patio with vertical herb garden for perfect relaxation retreat.

Loft 3b Old Town Best! It's 150 m2 (492 feet)
Immerse yourself in the historic charm and modern elegance of our 3-bedroom, 150 m2 loft in the heart of the Old Town. With wooden floors that radiate warmth and a modern open-plan kitchen ideal for sharing, this space guarantees a memorable vacation. Located on Avenida A, you'll find yourself just a few steps away from exquisite restaurants, museums, colonial churches, and the Casco's coveted rooftops, making every day an adventure.

The best view of the Old Town
Welcome to this charming accommodation located in the heart of Casco Viejo, on the third floor facing one of the most iconic squares in Panama, Plaza Catedral! Thanks to its privileged location, you will enjoy a unique view of the square and the imposing Cathedral Church. Right in this lively square, you will have at your disposal a wide variety of restaurants and shops where you can buy souvenirs of this wonderful trip.

Most Beautiful Loft in the Heart of Casco Viejo
Discover Casco Viejo from this beautiful loft, perfectly located. Casco Viejo, UNESCO World Heritage Site, known for its colonial buildings, and iconic streets. This vibrant neighborhood offers many restaurants, coffee places, museums, and an exciting night life. Just steps from Fonda Lo Que Hay, ranked among Latin America's Top 50 culinary destinations. Close to MYKA Greek Yogurt and the iconic La Compañía Hotel.

Full apartment in Panama
This charming apartment is located in one of the best neighborhoods in Panama, San Francisco, a downtown location where you will find ample cuisine, entertainment venues, close to bus stations, and the city's most important shopping mall, Multiplaza. This central and quiet apartment is an opportunity you won't want to miss. It offers the perfect combination of comfort, beauty, and a convenient location.
Popular amenities for Panamá Province vacation rentals
Other great vacation rentals in Panamá Province

Loft in Casco Antiguo, Joya Colonial

Luxury apt in Panama City 2 Rooms 3 Baths

w* | Luxury 2BR in Old Town

Saboga: El Remanso Beachfront Entire Upper Level

Apartment in Old Town, Panama

Panoramic Casco Viejo Lookout in The Sands

Gorgeous Flat in the best location in Casco Viejo

A warm and cozy flat in Casco Viejo
Destinations to explore
- Rentals with an EV charger Panamá Province
- House rentals Panamá Province
- Condo rentals Panamá Province
- Rentals with a fire pit Panamá Province
- Cabin rentals Panamá Province
- Pet-friendly rentals Panamá Province
- Fitness-friendly rentals Panamá Province
- Townhouse rentals Panamá Province
- Rentals with a kayak Panamá Province
- Rentals with a sauna Panamá Province
- Private suite rentals Panamá Province
- Rentals with a home theater Panamá Province
- Rentals with beach access Panamá Province
- Guesthouse rentals Panamá Province
- Family-friendly rentals Panamá Province
- Rentals with breakfast Panamá Province
- Hostel rentals Panamá Province
- Serviced apartment rentals Panamá Province
- Smoking-friendly rentals Panamá Province
- Boat rentals Panamá Province
- Apartment rentals Panamá Province
- Bed and breakfasts Panamá Province
- Vacation home rentals Panamá Province
- Nature eco lodge rentals Panamá Province
- Rentals with an accessible height bed Panamá Province
- Boutique hotels Panamá Province
- Rentals with a patio Panamá Province
- Tiny house rentals Panamá Province
- Waterfront rentals Panamá Province
- Loft rentals Panamá Province
- Beachfront rentals Panamá Province
- Rentals with outdoor seating Panamá Province
- Rentals with pools Panamá Province
- Villa rentals Panamá Province
- Rentals with a fireplace Panamá Province
- Rentals with lake access Panamá Province
- Hotel rooms Panamá Province
- Rentals with a hot tub Panamá Province
- Rentals with a washer and dryer Panamá Province
- Things to do Panamá Province
- Art and culture Panamá Province
- Sports activities Panamá Province
- Nature and outdoors Panamá Province
- Tours Panamá Province
- Sightseeing Panamá Province
- Food and drink Panamá Province
- Things to do Panama
- Food and drink Panama
- Art and culture Panama
- Nature and outdoors Panama
- Sightseeing Panama
- Tours Panama





