Guesthouse vacation rentals in Gainesville

Find and book unique guesthouse rentals on Airbnb

Top-rated guesthouse rentals in Gainesville

Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

0 of 0 items showing

1 of 3 pages

Top guest favorite

Guesthouse in Gainesville

4.92 out of 5 average rating, 131 reviews

Cozy Camper Stay

Experience camper life in a quiet neighborhood 20 minutes from the heart of Gainesville! Staying in a camper is a unique adventure! Before reserving, please note: ***NO SMOKING*** Shower and bunk beds CANNOT accommodate folks taller than 5'8". No TV or Wifi. Toilet is connected to a holding tank rather than traditional plumbing. If the valve is held open longer than necessary when flushing, odors from the tank can escape into the RV. There are steps getting in and out of the camper. Take care.

Guest favorite

Guesthouse in Gainesville

4.88 out of 5 average rating, 224 reviews

Sunflower Acres Cottage

Cute, cozy, freshly remodeled, private guest house on a beautiful 5 acre farm. Enjoy your own backyard herb garden with privacy fence, picnic table and fire pit. New kitchen with gas stove, microwave, toaster oven, coffee-maker, and dining area perfect for enjoying meals. The bedroom is equipped with a smart TV, queen bed, & extra blankets. This country getaway is near the University of Florida (12 miles), Blue Springs (21 miles) Ginnie Springs (24 miles), and historic High Springs (15 miles).

Top guest favorite

Guesthouse in Gainesville

5 out of 5 average rating, 101 reviews

"Nest" in the Guest House up in the Trees near UF

Kick back and "nest" in this calm, stylish and private space up in the trees in the heart of Gainesville, walking distance to the University of Florida and Ben Hill Griffin Stadium. The newly renovated guest house is filled with natural light, casual furnishings and simple Scandinavian style. If you are looking for a cozy getaway with all the amenities, a welcoming place to stay for pleasure, Gator sporting event, college visit, commencement, or business travel, with parking, look no further.

Top guest favorite

Guesthouse in Gainesville

4.93 out of 5 average rating, 102 reviews

Studio in the “Swamp”

400 square foot space located minutes from University Florida Campus,and Downtown Gainesville. Easy access to/from I-75 on Southside of Town via Williston Rd. Minutes from Archer Road and Celebration Pointe. This Bonus Room above the garage is completely separate from the main house. Access is provided through the garage with ample parking available. Great location for attending Gator Sports: Football, Basketball, baseball, etc. Enjoy the wildlife at Sweetwater Wetlands across the street!

Guest favorite

Guesthouse in Gainesville

4.95 out of 5 average rating, 255 reviews

Walk to UF! Historic King Bed Loft w/ Private Deck

If you are visiting Gainesville, look no further than Camellia Loft. This historic gem was built in 1924 and has been freshly renovated to bring it into the modern era. Enjoy the birdsong and majestic trees from your private deck overlooking the backyard—or relax inside as light streams through the loft's massive skylights. Only 0.5 miles to UF campus and exactly 1 mile to the stadium, you can easily walk to campus or games. Unwind by the shared fire pit or enjoy cooking on the grill

Top guest favorite

Guesthouse in Gainesville

4.97 out of 5 average rating, 580 reviews

Renovated Private Studio - Walking Distance to UF

NEWLY RENOVATED - Enjoy your Gainesville stay in this mid-century modern studio 0.5 miles from UF and 2 miles from UF and HCA hospitals. No detail was overlooked in this beautifully designed detached guest house with an abundance of natural light, upscale finishes, and endless amenities - kitchenette, mini fridge/freezer, smart TV, and more! This conveniently located private and quiet space in the heart of Gainesville is perfect for anyone visiting for just one night or a few weeks.

Top guest favorite

Guesthouse in Duckpond

5 out of 5 average rating, 116 reviews

Beautiful 1-Bedroom Guest House Historic District

Brand New One-Bedroom Guest House in the Historic District near Downtown Gainesville. This stylish, centrally-located rental is located in the backyard of our property and was designed by an architect on the historic board in the city of Gainesville, along with our son, who is also an architect. There is a fully-equipped kitchen, full bathroom and a bedroom with a queen-size bed. The ceilings are 9-feet high, giving a feeling of extra space in this 420-sq. foot guest house.

Top guest favorite

Guesthouse in Archer

4.96 out of 5 average rating, 183 reviews

Your own private space of peace and quiet.

Keep it simple at this peaceful and centrally-located place. While being only 15 miles from the nightlife of downtown Gainesville, this is country living at it best. With no street lights the stars are bright and easily counted. The mornings are bright and full of the music of bird songs. The cute 2 bedroom apartment (one double bed, two single beds) is on the SECOND FLOOR. It is easy to get lost in the whisper of the trees. This is a place to rest your soul and unwind.

Top guest favorite

Guesthouse in Oakview

5 out of 5 average rating, 112 reviews

Azalea Guesthouse - Close to UF and downtown

Lots of character in this brand-new guest house located in the heart of town on a quiet canopied neighborhood and walking distance to UF, stores and coffee shops. Wake up in the morning to birds singing in the lush backyard, enjoy your coffee on the deck, or an evening stroll around the quiet neighborhood. Just a few blocks from UF and downtown, this retreat is perfect for your next Gator game weekend or to enjoy the nature, art and culture Gainesville has to offer!

Top guest favorite

Guesthouse in Porters Community

4.91 out of 5 average rating, 232 reviews

Downtown Studio - 1/2 Mile from UF Campus

This Downtown Studio has just been remodeled and is located on a very private and tranquil property situated in the heart of Gainesville. Half a mile from UF Campus and 1.5 miles to Shands Hospital / VA. Within a few blocks are many of Gainesville's favorite restaurants, coffee shops, museums and nightlife. Facilities available are: Amazon Fire TV with access to Netflix and Prime TV; high speed internet; induction cook-top, coffee press, microwave and a fridge.

Superhost

Guesthouse in Lake City

4.88 out of 5 average rating, 1,095 reviews

Studio loft/ kitchenette/porch/bath

3 Miles from I75 exit 414 .studio apartment w/ porch over barn. Fire pit with wood available. Grill. Hammock swings under oaks. Stalls available. Close to riding/hiking trails in O'leno State Park. Close to springs for tubing/kayak/canoe. Ichetucknee Spring State Park, Ginny Springs, ++. Also 15 minutes from Santa Fe River and paddling/kayak/canoe rentals . Diving excursions available in High Springs. Quiet setting w/ pastures and grand daddy oaks.

Top guest favorite

Guesthouse in Micanopy

4.93 out of 5 average rating, 181 reviews

Private bed and bath above detached garage.

Close to Paynes Prairie Preserve State Park, Micanopy's unique downtown and a short easy drive to UF campus. North of Micanopy on Highway 441 across from Lake Wauberg. A common private driveway from the highway leads up to our two story home and two story detached garage. Uber not a good option. Good for couples, solo adventurers, and business travelers; and great for Gator friends and fans. Smoke free and no pets please.