
Pet-friendly vacation rentals in Florence County
Find and book unique pet-friendly homes on Airbnb
Top-rated pet-friendly home rentals in Florence County
Guests agree: these pet-friendly homes are highly rated for location, cleanliness, and more.

Kuker Cottage Downtown Florence-Near I95 & I20
Kuker Cottage is a beautifully restored Florence home in the heart of downtown. Perfectly situated halfway between New York and Florida, it is an ideal overnight stopping point. Plenty of space to spread out, offering families room to unwind after a long day of traveling. This home has been beautifully updated and is ready to host you, whether for a short or an extended stay. 2 queen beds, one twin bed, full bath, kitchen, wifi and TV. Walkable to parks and restaurants. 4 miles from I95 and I20

Comfortable 3BR Home Near McLeod & MUSC
This cozy three-bed, one-bath bungalow is minutes from downtown Florence and local medical facilities. Set in a small neighborhood, this cozy retreat is designed with extended-stay guests in mind. You’ll enjoy reliable WiFi, a smart TV, a fully equipped kitchen, the convenience of an in-unit washer and dryer, free onsite parking, a large front porch and a fenced in backyard. Whether you’re here for a few days or months, this house is a perfect space to call home. Please inquire about pet fees.

Gated and Private Catholic Hermitage house
Saint Michael Hermitage and retreat is a serene, gated, private home that is for 1-3 guests looking for a quiet stay while traveling or as a retreat destination. You will self check into your Hermitage after you obtain a gate code. There is a prayer chapel close by on the property. It is pet friendly for a well trained pet. There is Catholic iconography throughout the home. It is warm and inviting. There is a full kitchen, washer/dryer for your convenience and complementary coffee/tea.

Charming Home in Florence, SC
Welcome to Florence, South Carolina! This inviting 3-bedroom, 2-bathroom home is a haven of comfort and convenience. With four queen beds, it comfortably accommodates a group of friends or family. Step into the fully stocked kitchen, relax in the cozy living space, equipped with smart TVs for entertainment. The fenced backyard offers both privacy and a secure play area for your furry friends. Enjoy outdoor gatherings at the picnic table. Convenient amenities include a washer and dryer.

The Cottage at Dream Acres & Petting Zoo I-95/I-20
The Cottage at Dream Acres is situated with its own private drive on our 8 acre working horse farm located near Florence SC at the I-20/ I-95 corridor, 5 mins off the highway. We are the 1/2 way point between NY & FL. Relax and unwind from a long roadtrip or take a weekend farm-stay getaway. All the amenities of a larger home with the convenience of a smaller studio space! Family Friendly; sleeps up to 4, newly renovated in 2020, petting zoo, outdoor fire pit, tree swing, picnic table!

Quiet Townhome | King Bed | Easy I-95/I-20
Style meets Southern comfort in this West Florence gem. Sleeping up to 6, our quiet rowhome is the ultimate sanctuary after a long drive. Enjoy the luxury of a King-sized bed in the primary suite, outlets on every nightstand and a Smart TV in every room, or sip morning coffee on the private back patio. Tucked away from foot traffic yet only minutes from I-20/I-95, Florence Center, and the Florence Soccer Complex, we offer the perfect blend of total tranquility and city convenience.

Boho Private Downtown Stay Near I-95 & Hospital
Comfort, cleanliness, privacy, and personality! Perfect for overnight stays or longer terms. Come enjoy our Boho hideaway in the heart of Florence. Our place has all the amenities of a hotel with the comfort and privacy of your own home including covered parking for two vehicles. We are located within walking distance to downtown Florence and a 5 minute drive to all of the restaurants and shopping that Florence has to offer. Come stay at our guest house and make yourself at home!

Quiet farmhouse near the beach
The best memories are made on the farm. Life is just better away from the hustle and bustle of city lights and busy schedules. Come stay in this recently renovated fourth generation 1950s farmhouse on an 80 acre working farm. Unwind on the porch, walk trails, find millions of years old sharks teeth, build a bonfire, pick blackberries, swim in the ponds, collect walnuts, or just relax while you’re here but don’t forget to wish on a dandelion or a shooting star before you leave.

King Bed Close to I-95
Located just 5 mins from I-95 and 12 minutes from Florence, this quaint cottage sits on 6 acres with private deck, firepit & large back yard in a peaceful, country location. Your pets are welcome (max of 2, pls) but are not allowed on our beds. 🧺. King bed in master, 3 TV's (two 55” & one 32”), coffee bar with Keurig, strong WiFi. We also use 100% cotton sheets and quilts for your maximum sleeping comfort. ABSOLUTELY NO SMOKING OR VAPING ON OUR PROPERTY ($200 extra fee)!

Cottage by the Pool: Close to Interstates
Palm Trees, colorful flowers, hammocks and quiet space await in this tropic-like oasis just minutes from I-95/20. Hundreds of reviews acknowledge this idyllic setting. We are a Florence Airbnb favorite for travelers. We offer a queen bed, full bathroom, full sleeper sofa, strong wifi and TV. We even provide breakfast bars and coffee to help you jump start your day as you set off for the next journey. We look forward to hosting you.

Highway Oasis in Florence, Darlington & Hartsville
Welcome to this charming new house ideally situated close to both a major highway i 95 and i20 and the serene Myrtle beach, offering the perfect blend of convenience . Nestled in a great neighborhood, this residence boasts easy access to shopping center, ensuring that all your daily needs are just moments away. Very close to Florence Civic Center, 15 minutes to Buc-ee's Myrtle beach in 1 hr of a drive and shopping amenities.

Clean Cozy Cottage near I-20 & I-95
Quiet stay in the middle of Florence in this well established, peaceful neighborhood! Only 9 minutes from I-95 and I-20! Only 10 minutes to downtown Florence and 13 minutes to McLeod Regional Medical Center. Large, private, fully fenced in backyard Coffee bar w/ Keurig Strong, fast WiFi Smart TVs in Living Room and Master Bedroom Brand new appliances in kitchen For families: Pack N Play and basket full of toys.
Popular amenities for Florence County pet-friendly home rentals
Pet-friendly house rentals

Peaceful cabin retreat! Collins Quarters

Go With the Flo

Sleeps on the Creek!

Come Stay A While.

Home Sweet Home!

* NEW * Cozy and Clean 3B/2Bath

Can do condo!

Crystal Place Near MUSC and Mcleod Hospital
Private, pet-friendly home rentals

The Hideaway at Fox Fields

Saved by Grace Retreat 2 Rustic Creekside Cabins

Vintage Cottage at I-95 & I-20

The Hanna Farmhouse

Cozy & Convenient 1 Bd 1 Bath Apt. with/ Courtyard

Private apartment minutes from Darlington Raceway

Modern 1 bedroom condo near downtown Florence

Hide Away Studio Guesthouse
Destinations to explore
- Myrtle Beach Boardwalk
- Garden City Beach
- Huntington Beach State Park
- Broadway at the Beach
- Myrtle Beach State Park
- Family Kingdom Amusement Park
- Myrtle Beach SkyWheel
- Myrtle Waves Water Park
- Caledonia Golf & Fish Club
- Lakewood Camping Resort
- Murrells Inlet Marsh Walk
- WonderWorks Myrtle Beach
- Hollywood Wax Museum
- Captain George's Seafood Restaurant
- The Bowery
- Pelicans Ballpark
- Atalaya Castle
- Medieval Times Dinner & Tournament
- Topgolf
- Broadway Grand Prix
- Wild Water & Wheels
- The Pavilion Park
- Conway Riverwalk
- Ripley's Aquarium of Myrtle Beach




