Pet-friendly vacation rentals in DeSoto County

Find and book unique pet-friendly homes on Airbnb

Top-rated pet-friendly home rentals in DeSoto County

Guests agree: these pet-friendly homes are highly rated for location, cleanliness, and more.

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Superhost

The lake house is nestled among lush greenery, featuring large windows that provide views of the surroundings. Warm lights illuminate the exterior, creating a welcoming ambiance. A wooden deck leads to the entrance, surrounded by trees and natural landscaping.

Home in Hernando

4.86 out of 5 average rating, 242 reviews

Hernando Hideaway (Entire Lakehouse)

Enjoy our 2000 sq ft lake house in a private peaceful community with panoramic views of the lake. We are a licensed BNB with DeSoto County and the State of Mississippi until the year 2035. (Lic # 20110070) You will have the entire lake house to yourself and we provide coffee and pastries for breakfast. We are 15 minutes from Tunica Expo, 5 minutes to Tunica National Golf Course, 10 Minutes to the casinos; 38 minutes to Beale St, Bass Pro Shop, Peabody Hotel, Graceland and The Lorraine Hotel.

Top guest favorite

The en-suite bathroom features a spacious layout with an oversized vanity equipped with dual sinks and illuminated by elegant light fixtures. A glass-enclosed walk-in shower and a freestanding soaking tub are present, with a chandelier adding a touch of sophistication to the ambiance.

Home in Hernando

5 out of 5 average rating, 19 reviews

Peace of Heaven on a Hill

This Charming 2-Bedroom, 1 1/2 bath guest home is nestled on 4 acres right outside the city limits of Historic Hernando. Ideal for couples or small families, this home offers the perfect escape. Featuring an open concept kitchen/living space & a large master BR w/ an elegant bath suite. Enjoy time outdoors watching tv, relaxing on the porch swing, cooking on the grill, or gathering around the fire pit for s'mores. This home is located 10 miles from Snowden Grove & 1 Mile from Bolin Grove Farms

Top guest favorite

A winding pathway lined with gravel and stones leads to a charming farmhouse, framed by a large tree. The covered porch invites relaxation while greenery surrounds the home, offering a peaceful countryside ambiance.

Home in Lake Cormorant

5 out of 5 average rating, 36 reviews

Modern Farmhouse! Clean, Private, Spacious!

Forget your worries in this spacious and serene space. This renovated farmhouse dates back to the early 1900’s. Boasting large rooms and tall ceilings with abundant common areas and a modern farmhouse vibe with plenty of original character. 4 bedrooms, 3.5 baths, formal living room, den, formal dining, kitchen, laundry room, covered front porch, courtyard with water fountain, back patio overlooks 4 wooded acres with dining and fire pit table. Side patio off the private queen suite. Owner/Agent

Top guest favorite

A charming two-story Colonial home is displayed, featuring a wraparound porch with black railings. The exterior is painted in light hues, complemented by dark shutters. Lush greenery surrounds the property, offering a welcoming atmosphere, with sunlight filtering through the trees in the background.

Home in Hernando

5 out of 5 average rating, 22 reviews

Four Bedroom Home - King Bed - Full Kitchen

Beautiful Colonial home perfect for up to 8 guests. Complete with four bedrooms, two and a half baths, master bedroom has its own private bathroom, a two-car garage, full kitchen, appliances, washer and dryer, wi-fi, TV, and security system -- all to yourself. Very quiet and peaceful – centered on the historic Hernando Square. Relax and spend your day with free access to the nearby Hernando Golf & Racquet Club as part of your stay with dinning, swimming pool, golf and tennis available.

Guest favorite

The exterior of the cottage is framed with natural wood and features a screened porch, allowing for views of the surrounding forest. A wooden staircase leads to the entrance, and a stone pathway guides visitors through the lush, green landscape.

Cottage in Coldwater

4.95 out of 5 average rating, 176 reviews

Wynnewood - Odell Cottage

Country get-away! Only 30 Minutes from Downtown Memphis, TN, yet out in the country on a 62 acre estate. Nature trails through the property allow for beautiful, peaceful strolls. We have fishing (in season). **** This cottage is set back in the woods and there is not a TV in this unit but there is Wifi. We have created a serene and unplugged experience. We have the "Wynnewood Elizabeth Cottage" and the "Wynnewood Jettie Jewel cottage" on our property that are listed separately.

Guest favorite

A spacious living area is featured, highlighting a reclining couch and a round coffee table in the center. A large flat-screen TV is mounted on the wall, and natural light enters through the window. Barstools line the kitchen island in the background.

Home in Olive Branch

4.87 out of 5 average rating, 15 reviews

3BD/2BA Home w/ 2-Car Garage & Private Backyard

The Space • Smart TVs in the living room and owner suite • Enclosed backyard with patio set • Fully stocked kitchen • Smart washer and dryer • Central AC and heating • 2-car garage plus driveway parking • Keyless entry • Super-fast WiFi • Dedicated workspace Sleeping Arrangements • King bed in owner suite • Queen beds in other bedrooms Additional Features • Owner suite with soaking tub and shower • Dining room • Reclining couch • Exterior security system

Top guest favorite

A guesthouse is nestled among green trees and lush grass, with a pathway leading to a bright red door. Two small chairs are positioned in front of the entrance, inviting guests to relax in the outdoor space.

Guesthouse in Hernando

4.99 out of 5 average rating, 128 reviews

Cozy 2 Bedroom Guesthouse in a Relaxing Setting

Our two bedroom, two bath guesthouse is the perfect get-a-way from it all, yet close enough to everything you're looking to do: 3 minutes to the historic Hernando Town Square, 10 minutes to the MS River Delta and Historic Hwy 61, 12 minutes to Tanger Outlets & Landers Center in Southaven, 20 minutes to Snowden Grove Ballfields & Amphitheatre in Southaven, 23 minutes to Tunica Casino Strip, 25 minutes to Midtown/Downtown Memphis, 1 hour to Oxford, MS and 1 hour to Clarksdale, MS.

Guest favorite

The compact kitchen features wooden walls and open shelving, displaying colorful pots and dishes. A stainless steel refrigerator and countertop appliances are visible, along with a sink and wooden countertop. A mounted artwork of a Longhorn adds character to the space.

Farm stay in Southaven

4.98 out of 5 average rating, 123 reviews

The Longhorn Tiny House: Farm Stay Near Memphis

Escape to The Longhorn House, a cozy tiny house on 38 acres of rolling hills near Memphis, TN. Explore the countryside, fish or canoe on Blue Haze Lake, and enjoy sunsets with grazing miniature Longhorns. Relax at the outdoor seating area, grill out, or watch a movie under the stars at our outdoor theater. Inside, enjoy memory foam bedding, TVs, records, and board games. Just minutes from Memphis and Graceland, this is your perfect escape to nature and comfort.

Superhost

A spacious sleeping area features a large white bed adorned with elegant black and silver bedding. Two nightstands with lamps are placed on either side, while mirrors reflect the room's design. Dark walls and wooden flooring create a modern, cohesive look.

Home in Southaven

4.78 out of 5 average rating, 23 reviews

Southern Charm near Silo Square

Bring the whole family to this great place with lots of room for fun. 1 mile from Snowden Grove 5 miles from the Civic Center 10 miles from Memphis International Airport 20 miles from downtown Memphis A host of delicious restaurants within walking distance and some of the best eateries around nearby. Please reach out if you need suggestions. Electric and gas grills available. Fully stocked coffee bar. All bedrooms equipped with smart TVs.

Superhost

Home in Southaven

5 out of 5 average rating, 3 reviews

Memphis/Southaven Full 1200 Sq Ft Home Nurse Nest

Perfect for traveling nurses, Doctors, workers, insurance claims OR long stay or short stay peaceful and centrally-located place. Close to hospitals, University college, Delta College, Graceland, Beal Street, Snowden Grove Baseball Complex, Landers Stadium & Arena, Memphis Airport, Casino, Church, Walmart, Hospitals, Sam’s, Eating Places Spacious and very quiet one bedroom, full kitchen with washer and dryer, salon bath. Pet welcome.

Guest favorite

The exterior of the house is shown, featuring a modern design with a covered porch and two symmetrical large windows framed in dark accents. A stone chimney rises from one side, while well-maintained grass lines the pathways leading to the entrance.

Home in Hernando

4.97 out of 5 average rating, 29 reviews

Relaxing Row House in Downtown Hernando

Enjoy this relaxing 2-bedroom 2-bathroom house in walking distance to restaurants, bars, and boutiques for shopping. This relaxing home is located in downtown Hernando, Mississippi. With less than a 30 minute drive to Memphis, a 10 minute drive to Southaven, and less than an hour to Oxford, this location offers various day trip opportunities!

Guest favorite

A cozy living area features a gray sofa and armchair, arranged around a circular coffee table. A television is mounted above a stylish fireplace, while a decorative wall piece adds character to the space. Soft lighting is provided by a floor lamp and a side table lamp.

Home in Southaven

4.96 out of 5 average rating, 23 reviews

Southaven Hideaway near Shopping

Cozy and secure modern home with relaxing back patio in quiet Southaven neighborhood! Minutes from Starbucks, outlet malls, restaurants, and shopping…easy access to I-55 and the Memphis Airport. Premium bedding, well equipped kitchen, garage parking and blazing WiFi make this a perfect travel home!