Vacation rentals in DeSoto County

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Top-rated vacation rentals in DeSoto County

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Superhost

The lake house is nestled among lush greenery, featuring large windows that provide views of the surroundings. Warm lights illuminate the exterior, creating a welcoming ambiance. A wooden deck leads to the entrance, surrounded by trees and natural landscaping.

Home in Hernando

4.87 out of 5 average rating, 247 reviews

Hernando Hideaway (Entire Lakehouse)

Enjoy our 2000 sq ft lake house in a private peaceful community with panoramic views of the lake. We are a licensed BNB with DeSoto County and the State of Mississippi until the year 2035. (Lic # 20110070) You will have the entire lake house to yourself and we provide coffee and pastries for breakfast. We are 15 minutes from Tunica Expo, 5 minutes to Tunica National Golf Course, 10 Minutes to the casinos; 38 minutes to Beale St, Bass Pro Shop, Peabody Hotel, Graceland and The Lorraine Hotel.

Top guest favorite

Home in Southaven

5 out of 5 average rating, 27 reviews

Modern Comfort: Perfect Location | Southaven, MS

Please Read The Rules! Modern retreat tucked away in a peaceful, no-traffic cove. This stylish home blends comfort and convenience. Enjoy the quiet surroundings while staying close to everything! You’re centrally located near the best of the area: just 10 minutes from Landers Center & Tanger Outlets, 13 minutes from historic Graceland & 4 mins from Baptist Desoto Hospital. This home offers the ideal mix of modern comfort and unbeatable access to Southaven, Memphis & Olive Branch hotspots.

Guest favorite

The exterior of the cottage is framed with natural wood and features a screened porch, allowing for views of the surrounding forest. A wooden staircase leads to the entrance, and a stone pathway guides visitors through the lush, green landscape.

Cottage in Coldwater

4.94 out of 5 average rating, 180 reviews

Wynnewood - Odell Cottage

Country get-away! Only 30 Minutes from Downtown Memphis, TN, yet out in the country on a 62 acre estate. Nature trails through the property allow for beautiful, peaceful strolls. We have fishing (in season). **** This cottage is set back in the woods and there is not a TV in this unit but there is Wifi. We have created a serene and unplugged experience. We have the "Wynnewood Elizabeth Cottage" and the "Wynnewood Jettie Jewel cottage" on our property that are listed separately.

Guest favorite

The exterior of the home features a well-maintained facade with large windows framed by manicured greenery. A gentle rise of steps leads to the entrance, surrounded by lush lawns and mature trees under a clear blue sky.

Home in Olive Branch

4.97 out of 5 average rating, 58 reviews

Pleasant Hill Estate

Welcome to our unique and stylish home, nestled in a serene environment. With thoughtful amenities & a warm ambiance, you’ll never regret choosing to stay here. The property features elegant architectural design with natural stones, providing a harmonious blend of elegance and natural beauty. The well-maintained exterior, with a beautiful lake and inviting landscaping, adds to the overall appeal of the 8-acre land with oak and magnolia trees. Book your unforgettable experience today!

Guest favorite

The front of a two-story brick house features a gabled roof and a white garage door. A well-maintained driveway leads to the entrance, bordered by green grass and trees in the background. A clear blue sky provides a bright backdrop.

Home in Southaven

4.86 out of 5 average rating, 58 reviews

Family Getaway Home

Bring the family to enjoy. We offer lots of room for you to enjoy during your stay. 4 bedrooms with one of them having a full size air hockey table. Home offers a covered patio to sit and enjoy as well. Home is located in a nice quiet cove in the heart of DeSoto County. This home is convenient to lots of great restaurants and things to do. Downtown Memphis is a short 25 minute drive as well , home of the Memphis Tigers. Come , relax , and enjoy . Note - This is a nonsmoking home 😊

Top guest favorite

A guesthouse is nestled among green trees and lush grass, with a pathway leading to a bright red door. Two small chairs are positioned in front of the entrance, inviting guests to relax in the outdoor space.

Guesthouse in Hernando

4.99 out of 5 average rating, 138 reviews

Cozy 2 Bedroom Guesthouse in a Relaxing Setting

Our two bedroom, two bath guesthouse is the perfect get-a-way from it all, yet close enough to everything you're looking to do: 3 minutes to the historic Hernando Town Square, 10 minutes to the MS River Delta and Historic Hwy 61, 12 minutes to Tanger Outlets & Landers Center in Southaven, 20 minutes to Snowden Grove Ballfields & Amphitheatre in Southaven, 23 minutes to Tunica Casino Strip, 25 minutes to Midtown/Downtown Memphis, 1 hour to Oxford, MS and 1 hour to Clarksdale, MS.

Guest favorite

Home in Southaven

4.96 out of 5 average rating, 23 reviews

Spacious & Stylish~5 min to Landers+Fenced Yard!

Welcome to Miss Zen – Your Cozy Southaven MS Getaway! Tucked away in a quiet, safe Southaven neighborhood, your home away from home! ☆18 min to Memphis Airport ☆12 min to Snowden Grove Amphitheater ☆5 min to Landers Center ☆17 min to Graceland ☆Fenced yard ☆USB plug in ☆Free parking ☆Dedicated workspace ☆2 King beds ☆Roku TV in both bedroom ☆BBQ ☆Patio with Pergola ☆Fully stocked kitchen ☆Self check-in/digital guide book ☆5 min walk to park ☆Twin serta futon for an added guest

Guest favorite

A single-story brick home features a gently sloped front yard adorned with green shrubs and seasonal flowers. The entrance is complemented by a black railing leading to the front door beneath a covered porch. Tall trees frame the property, providing natural shade.

Home in Hernando

4.9 out of 5 average rating, 62 reviews

Hernando Retreat! Private, Clean, Spacious!

Hernando Retreat is located in a quiet residential neighborhood and features two bedrooms and two baths. King size bed with 2 closets, Full size bunk beds with 2 closets. Laundry Room, Kitchen with basic cooking utensils, microwave, coffee machine, dishwasher, dining table and bar offers seating for 7, covered carport/patio, outdoor seating area, concrete parking. Walk to town events from this central location. Shopping and dining nearby! Super Clean and Cozy! Owner/Agent!

Superhost

Home in Hernando

4.67 out of 5 average rating, 12 reviews

Three Bedroom Home - King Bed - Full Kitchen

Beautiful Colonial home perfect for up to 6 guests. Complete with three bedrooms, three and a half baths, master bedroom has its own private bathroom, full kitchen, appliances, washer and dryer, wi-fi, TV, and security system -- all to yourself. Very quiet and peaceful – centered on the historic Hernando Square. Relax and spend your day with free access to the nearby Hernando Golf & Racquet Club as part of your stay with dinning, swimming pool, golf and tennis available.

Guest favorite

A white picket fence frames the entrance to a wooded area as the sun sets, casting shades of pink and orange across the sky. Leafless trees stand along the winding path that leads deeper into the serene surroundings.

Home in Hernando

4.92 out of 5 average rating, 144 reviews

DeerRun:Hidden Gem with Woods,Wildlife,and Gardens

Deer Run is close to Memphis,TN, I-55, restaurants and dining, great views. The spacious, 750+ sq ft cottage on 10 acres is good for retiree, couple, solo and business travelers alike. We look forward to sharing our property in this semi-secluded setting. Come relax in the comfy 12 inch deep foam mattress with super soft sheets. Enjoy the splendor of the woods, wildlife and gardens. We are far enough off the road that you will not see the street. Wheelchair accessible.

Guest favorite

A vibrant stained glass panel is prominently displayed on the side of a rustic wooden structure, capturing sunlight. Adjacent to it, a shiny vintage Airstream trailer reflects the outdoors, offering a unique glamping experience surrounded by nature.

Farm stay in DeSoto County

4.93 out of 5 average rating, 41 reviews

ELVIS Themed! Grazeland Vintage Airstream Farmstay

This Vintage Airstream has been fully renovated to bring it back to its former glory! There’s a full size bed and memory foam futon to accommodate 4. We have a gas cooktop, air fry microwave oven combo and outdoor gas grill to prepare perfect camping meals. We have 2 tvs inside and 1 outside. There’s an awesome sound system to listen to your favorite tunes. The best part of this Glamping experience is the beautiful outdoor bathing space perfect for relaxing!

Top guest favorite

The tiny house features a rustic wooden exterior with a red metal roof. Soft ambient lights are strung around the door area, which is framed by greenery and flower beds. Outdoor seating is provided by two white chairs on a gravel patio, creating a welcoming space.

Tiny home in Olive Branch

4.98 out of 5 average rating, 143 reviews

The Pony

-Boasting a small hoofprint of 128 square feet with a loft. Ideally situated in a safe area for those visiting/passing through Memphis. -Tranquil views of open fields, horses, and a variety of other furry friends at a working horse boarding barn. -Stay solo or with someone you don't mind cozying up to. Ideal for mobile guests comfortable with stairs and tighter spaces. Locals or those without positive reviews will be rejected. Our property is non smoking.