Vacation rentals in DeSoto County

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in DeSoto County

Guests agree: these stays are highly rated for location, cleanliness, and more.

1 of 1 pages1 / 1

Top guest favorite

The en-suite bathroom features a spacious layout with an oversized vanity equipped with dual sinks and illuminated by elegant light fixtures. A glass-enclosed walk-in shower and a freestanding soaking tub are present, with a chandelier adding a touch of sophistication to the ambiance.

Home in Hernando

5.0 out of 5 average rating, 43 reviews

Peace of Heaven on a Hill

This Charming 2-Bedroom, 1 1/2 bath guest home is nestled on 4 acres right outside the city limits of Historic Hernando. Ideal for couples or small families, this home offers the perfect escape. Featuring an open concept kitchen/living space & a large master BR w/ an elegant bath suite. Enjoy time outdoors watching tv, relaxing on the porch swing, cooking on the grill, or gathering around the fire pit for s'mores. This home is located 10 miles from Snowden Grove & 1 Mile from Bolin Grove Farms

Guest favorite

A winding pathway lined with gravel and stones leads to a charming farmhouse, framed by a large tree. The covered porch invites relaxation while greenery surrounds the home, offering a peaceful countryside ambiance.

Home in Lake Cormorant

4.98 out of 5 average rating, 47 reviews

Modern Farmhouse! Clean, Private, Spacious!

Forget your worries in this spacious and serene space. This renovated farmhouse dates back to the early 1900’s. Boasting large rooms and tall ceilings with abundant common areas and a modern farmhouse vibe with plenty of original character. 4 bedrooms, 3.5 baths, formal living room, den, formal dining, kitchen, laundry room, covered front porch, courtyard with water fountain, back patio overlooks 4 wooded acres with dining and fire pit table. Side patio off the private queen suite. Owner/Agent

Superhost

A cozy living room area is depicted featuring a brown couch adorned with a variety of decorative pillows in different patterns. A small table holds a vase of vibrant sunflowers. Colorful artwork adorns the wall above the couch, complemented by a patterned rug on the floor.

Home in Southaven

4.67 out of 5 average rating, 97 reviews

warm and peaceful home in Southaven Central Park

Heart of southaven. 10-15 minutes to access everything in southaven such as food, shopping mall, outlet, hospital, airport etc. Peace and safe environment to enjoy getaway and visiting 25 minutes-Memphis downtown, bill street, fedex forum 25 minutes-Horseshoe Casino (Tunica) 15 minutes-Memphis International Airport 13 minutes-Graceland (home of Elvis Presley) 9 minutes -Landers Center. 8 minutes-Tanger Outlet. 7 minutes -Silo Bank Amphitheater in Snowden Grove 5 minutes-Interstate 55. enjoy!

Top guest favorite

Home in Southaven

5.0 out of 5 average rating, 45 reviews

Stylish & Cozy~5 min to Landers CTR+ Fenced Yard!

Step into this stylish and comfortable living area. The home features two spacious bedrooms and a double futon for extra guests. Located just minutes from great dining and shopping. Fully fenced yard! ☆18 min to Memphis Airport ☆12 min to Snowden Grove ☆5 min to Landers ☆17 min to Graceland ☆Fenced yard ☆USB plug in ☆Free parking ☆Dedicated workspace ☆Washer/Dryer ☆Roku TV in both bedroom ☆BBQ ☆Patio with Pergola ☆Fully stocked kitchen ☆Self check-in/digital guide book ☆5 min walk to park

Superhost

Home in Southaven

4.91 out of 5 average rating, 43 reviews

Modern Comfort: Perfect Location | Southaven, MS

Please Read Before Booking!!! Modern retreat tucked away in a peaceful, no-traffic cove. This stylish home blends comfort and convenience. Enjoy the quiet surroundings while staying close to everything! You’re centrally located near the best of the area: just 10 minutes from Landers Center & Tanger Outlets, 13 minutes from Graceland & 4 mins from Baptist Desoto Hospital. This home offers the ideal mix of modern comfort and unbeatable access to Southaven, Memphis & Olive Branch hotspots.

Guest favorite

A charming two-story Colonial home is displayed, featuring a wraparound porch with black railings. The exterior is painted in light hues, complemented by dark shutters. Lush greenery surrounds the property, offering a welcoming atmosphere, with sunlight filtering through the trees in the background.

Home in Hernando

4.92 out of 5 average rating, 51 reviews

Four Bedroom Home - King Bed - Full Kitchen

Beautiful Colonial home perfect for up to 8 guests. Complete with four bedrooms, two and a half baths, master bedroom has its own private bathroom, a two-car garage, full kitchen, appliances, washer and dryer, wi-fi, TV, and security system -- all to yourself. Very quiet and peaceful – centered on the historic Hernando Square. Relax and spend your day with free access to the nearby Hernando Golf & Racquet Club as part of your stay with dinning, swimming pool, golf and tennis available.

Superhost

The front of a two-story brick house features a gabled roof and a white garage door. A well-maintained driveway leads to the entrance, bordered by green grass and trees in the background. A clear blue sky provides a bright backdrop.

Home in Southaven

4.86 out of 5 average rating, 76 reviews

Family Getaway Home

Bring the family to enjoy. We offer lots of room for you to enjoy during your stay. 4 bedrooms with one of them having a full size air hockey table. Home offers a covered patio to sit and enjoy as well. Home is located in a nice quiet cove in DeSoto County. This home is convenient to lots of great restaurants and things to do. Downtown Memphis is a short 25 minute drive as well .Come , relax , and enjoy . Note -This is a nonsmoking home and I do not rent to locals , some exceptions .

Guest favorite

The exterior of the home features a well-maintained facade with large windows framed by manicured greenery. A gentle rise of steps leads to the entrance, surrounded by lush lawns and mature trees under a clear blue sky.

Home in Olive Branch

4.96 out of 5 average rating, 72 reviews

Pleasant Hill Estate

Welcome to our unique and stylish home, nestled in a serene environment. With thoughtful amenities & a warm ambiance, you’ll never regret choosing to stay here. The property features elegant architectural design with natural stones, providing a harmonious blend of elegance and natural beauty. The well-maintained exterior, with a beautiful lake and inviting landscaping, adds to the overall appeal of the 8-acre land with oak and magnolia trees. Book your unforgettable experience today!

Guest favorite

The open loft features cathedral ceilings with six skylights, allowing ample natural light to illuminate the spacious living area. A wooden staircase leads to the upper level, while a dining area and kitchen are visible in the background. Comfortable seating arrangements create an inviting space.

Home in DeSoto County

4.96 out of 5 average rating, 108 reviews

Whispering Winds! (Hot Tub and Pool)

Whispering Wind Sunsets is built on the Mississippi Delta Bluff overlooking thousands of acres of farmland towards the west which has gentle breezes and beautiful sunsets. The house is an open loft concept with cathedral ceilings and six skylights . The natural light lets you enjoy a 26 foot vertical expanse of the living room, dining room and kitchen. Whispering Wind Sunsets is next door to The Hernando Hideaway. Rent them both for larger family gatherings! Disability Accessible!

Top guest favorite

A guesthouse is nestled among green trees and lush grass, with a pathway leading to a bright red door. Two small chairs are positioned in front of the entrance, inviting guests to relax in the outdoor space.

Guesthouse in Hernando

4.99 out of 5 average rating, 141 reviews

Cozy 2 Bedroom Guesthouse in a Relaxing Setting

Our two bedroom, two bath guesthouse is the perfect get-a-way from it all, yet close enough to everything you're looking to do: 3 minutes to the historic Hernando Town Square, 10 minutes to the MS River Delta and Historic Hwy 61, 12 minutes to Tanger Outlets & Landers Center in Southaven, 20 minutes to Snowden Grove Ballfields & Amphitheatre in Southaven, 23 minutes to Tunica Casino Strip, 25 minutes to Midtown/Downtown Memphis, 1 hour to Oxford, MS and 1 hour to Clarksdale, MS.

Guest favorite

A spacious bedroom features a large bed with a decorative quilt and accent pillows. Side tables with lamps are positioned on each side. Natural light enters from a sliding glass door, while a framed piece of wall art adds a touch of color.

Home in DeSoto County

5.0 out of 5 average rating, 6 reviews

Pickleball House at Bonne Terre

Relaxing property located in Nesbit, MS: Fantastic stay for the Blues Trail, Memphis, Oxford, Snowden Grove, or a pickleball weekend getaway! NO EVENTS ALLOWED OR HAVING OVER THE GUEST AMOUNT LISTED With this listing you get access to a PICKLEBALL COURT! Staying here you get included access to our courts, a free daily basic continental breakfast, and our outdoor pool. This is on the Bonne Terre property that also has a wedding venue as well as an AMAZING RESTAURANT!

Guest favorite

Home in Hernando

4.93 out of 5 average rating, 14 reviews

Private 3-Acre Estate with Resort-Style Pool

Experience total privacy on this elite 3.3-acre estate! Perfect for family getaways, baseball travelers, or anyone seeking a high-end retreat. Relax by the private unheated pool, fire up the guest-favorite BBQ grill, enjoy a screen porch, or use the professional chef's kitchen. Just 17 minutes to Snowden Grove and close to the city. Featuring a massive 9-seat bar, fire pit, ping-pong, cornhole, and lightning-fast 1G fiber Wi-Fi. Your secluded sanctuary awaits!