House vacation rentals in Des Moines
Find and book unique houses on Airbnb
Top-rated house rentals in Des Moines
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Des Moines house rentals
House rentals with a pool
Home in West Des Moines
4.97 out of 5 average rating, 37 reviewsCute West Des Moines Guest House
Jul 15 – 22
Home in Urbandale
4.99 out of 5 average rating, 68 reviewsPrivate Pool (May-Sept) | Dog Friendly | 2bd 1ba
Jul 28 – Aug 4
Home in Des Moines
4.88 out of 5 average rating, 33 reviewsUrban Oasis: Cozy Gathering Spot/Retreat - Hot Tub
Dec 19 – 26
Home in Ankeny
4.97 out of 5 average rating, 77 reviewsHistoric Home on 4 Acres - Hot Tub, Pool, Tiki Bar
Apr 18 – 25
Home in Urbandale
4.88 out of 5 average rating, 17 reviewsThe Estate
Nov 12 – 19
Home in Grimes
5.0 out of 5 average rating, 53 reviewsSleeps 12, Spacious, Family Friendly (w/ Pool!)
Aug 29 – Sep 5
Home in Ankeny
4.85 out of 5 average rating, 123 reviewsFive Star Modern Farmhouse Indoor Hot Tub for 8.
Jan 26 – Feb 2
Home in Ankeny
4.85 out of 5 average rating, 34 reviewsComfortable and Spacious Five Bedroom Home
Oct 7 – 14
Weekly house rentals
Home in Des Moines
4.84 out of 5 average rating, 243 reviewsCozy Spa Home Close to Downtown
Home in Collins
4.9 out of 5 average rating, 124 reviewsSmall town living with big city access.
Apr 15 – 22
Home in Des Moines
4.84 out of 5 average rating, 118 reviewsForget The Hotel Self Check In- On-Site Parking
Home in Des Moines
4.88 out of 5 average rating, 144 reviewsCharming Des Moines Home with a GREAT location!
Feb 15 – 22
Home in Des Moines
4.98 out of 5 average rating, 133 reviewsThe Cow Tipper: Spa • Game Room • Fire Pit • BBQ
Mar 13 – 20
Home in Des Moines
4.84 out of 5 average rating, 150 reviewsCharming 4 Bedroom Home With Beautiful Backyard
Jul 8 – 15
Home in Des Moines
4.88 out of 5 average rating, 382 reviewsGarden Retreat Near Downtown
Nov 22 – 29
Home in Des Moines
4.89 out of 5 average rating, 190 reviewsThe little CABIN escape
Jul 15 – 22
Private house rentals
Home in Des Moines
5.0 out of 5 average rating, 15 reviewsAshby Park Rental with beautiful view
Mar 25 – Apr 1
Home in Des Moines
5.0 out of 5 average rating, 12 reviewsSunny, Cozy 2 Bedroom Stay
Dec 8 – 15
Home in Des Moines
4.91 out of 5 average rating, 43 reviewsThe Office
Aug 19 – 26
Home in Des Moines
4.96 out of 5 average rating, 95 reviewsWoodland Heights hist. district house on the hill.
Nov 11 – 18
Home in Des Moines
4.92 out of 5 average rating, 90 reviewsCozy Bungalow Home-Central Des Moines
Sep 18 – 25
Home in Waukee
4.97 out of 5 average rating, 35 reviews2 Bed 2 Bath
Oct 13 – 20
Home in Des Moines
4.98 out of 5 average rating, 57 reviewsFully Fenced Retro 1948 Mid-century Metal Lustron
Jul 20 – 27
Home in Des Moines
4.97 out of 5 average rating, 31 reviewsCozy Cute Bungalow
Sep 29 – Oct 6
Quick stats about house rentals in Des Moines
Total rentals
360 properties
Wifi availability
360 properties include access to wifi
Rentals with dedicated workspaces
230 properties have a dedicated workspace
Pet-friendly rentals
150 properties allow pets
Family-friendly rentals
250 properties are a good fit for families
Total number of reviews
18K reviews
Destinations to explore
- Ames Vacation rentals
- Pella Vacation rentals
- West Des Moines Vacation rentals
- Waterloo Vacation rentals
- Ankeny Vacation rentals
- Cedar Falls Vacation rentals
- Lake View Vacation rentals
- Fairfield Vacation rentals
- Lake Red Rock Vacation rentals
- Waverly Vacation rentals
- Lake Panorama Vacation rentals
- Boone Vacation rentals
- Earth house rentals United States
- Guesthouse rentals United States
- House rentals United States
- Townhouse rentals United States
- Lighthouse rentals United States
- Kid-friendly rentals Des Moines
- Pet-friendly rentals Des Moines
- Rentals with outdoor seating Des Moines
- Monthly Rentals Des Moines
- Rentals with breakfast Des Moines
- Rentals with a hot tub Des Moines
- Rentals with a fire pit Des Moines
- Rentals with a patio Des Moines
- Apartment rentals Des Moines
- Fitness-friendly rentals Des Moines
- Rentals with a washer and dryer Des Moines
- Rentals with a fireplace Des Moines
- Rentals with pools Des Moines
- Townhouse rentals Iowa
- Lakehouse rentals Iowa
- Tiny house rentals Iowa
- House rentals Iowa
- Guesthouse rentals Iowa
- Townhouse rentals Iowa
- Lakehouse rentals Iowa
- Tiny house rentals Iowa
- House rentals Iowa
- Guesthouse rentals Iowa
- House rentals Ames
- Townhouse rentals Polk County
- House rentals Polk County
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom