
Vacation rentals in De Soto
Find and book unique accommodations on Airbnb
Top-rated vacation rentals in De Soto
Guests agree: these stays are highly rated for location, cleanliness, and more.

Eagle View Lodge - 1850's Log Cabin w/ Hot Tub
In the heart of the Driftless, atop the Mississippi , enjoy the tranquility of a centuries-old Appalachian cabin. Relax on the deck & take in dramatic sunsets, soaring eagles & glistening stars. Soak in the hot tub & gaze at the majestic Mississippi. Host unforgettable dinners in the screened deck & share stories by the fireplace. Only 30 mins from Viroqua & Prairie du Chien, experience the natural beauty of the driftless region - hiking, fishing, hunting, biking - whatever inspires you.
4.99 out of 5 average rating, 110 reviews
Scenic Valley Lodge- HOT TUB & Pool!
Located on the edge of Lansing, IA and just minutes away from the Mississippi river. Rustic and modern look featuring 3 levels with 1 bathroom in each level. Beautiful bluff views from windows in every floor. This property is located only a few minutes from the Mississippi River , mount hosmer and Lansing bridge to cross to WI. Boat landing is a 5 min drive Pool is only available Memorial Day to Labor Day weekend ! It is NOT a heated pool , and is outdoors. The garage is off limits and locked
4.83 out of 5 average rating, 104 reviews
Barn On The Ridge / HOT TUB / Sleeps 6
Kick back & relax in this cozy, stylish cabin with beautiful river views during all seasons. Enjoy evening dinners on the screened in porch, sip your coffee from the upper deck & unwind in a luxurious hot tub! This loft style cabin was crafted in 2020 & has sleeping space for up to 6 guests, featuring a king bed, full size bed & full size futon. You’ll be minutes from De Soto & Lansing area and only 30 minutes to the La Crosse area! See all 7 properties with Hot Tubs at Rentals Justin Time.
4.91 out of 5 average rating, 159 reviews
Cozy Sportsman's Hideaway
Enjoy the outdoors in this cozy getaway. Sportsman will love the close to 14 acres of hunting, hiking hiking and Coulee Creek which is a class 1 trout stream just 1/2 mile down the road (shown in pictures). The cabin boasts a large deck for enjoying the woodland views. On those chilly evenings warm yourself beside the outdoor fire pit. Why compromise when this cabin offers a pleasant stay decorated with rustic decor, comfortable Hickory furniture, modern amenities and peaceful surroundings.
4.93 out of 5 average rating, 80 reviews
Big River Retreat
Perfect destination for quiet get away or a family/friends reunion with direct view of Mississippi River. Peaceful, rustic, 3 level home with plenty of space with 5 bedrooms, 3.5 baths, vaulted ceiling great room with spectacular beams creating perfect gathering space for guests. Gas fireplace & coffee bar add to charm. Full kitchen & laundry. Enjoy outdoors with full wrap around deck & walk out patio & firepit in back. Lg drive thru garage allows ease of pulling boat. 5 min drive to town.
4.99 out of 5 average rating, 96 reviews
Aspenshire Cabin: A Nod to English Charm
Aspenshire Cabin is nestled in a valley overlooking a private stream. The Driftless Region is known for its rolling hills and beautiful landscapes. This newly remodeled cabin stands in striking contrast to the woods surrounding it. Inspired by the cozy + sophisticated vibes of Old English Charm, a nod to this design style is evident throughout. Guests are welcomed into a space curated for rest and relaxation, whether through a quiet retreat for the arts or a getaway with family and friends.
4.99 out of 5 average rating, 111 reviews
Rustic Ridge Chalet, hot tub & amazing river view!
Kick back and relax in this calm, stylish space. This recently purchased and renovated cabin is exactly where you want to be! * Hot Tub * River View * Privacy * King bed in loft * Queen murphy bed * 2 bathrooms * Cable TV, 2 smart TV's , Wi-Fi * Wrap around deck * Fire pit * Gas stove fireplaces, just flip switch * Kitchen items included (cookware, etc) * Gas grill * Bed & bath linens supplied * Games, books * PEACE & QUIET * We do allow dogs ($110/stay) max 2 dogs. NOT LEFT UNATTENDED
4.94 out of 5 average rating, 120 reviews
Sunsets on the Mississippi River
Experience the romantic allure of the mighty Mississippi . This idyllic Driftless retreat offers everything you need for a tranquil getaway, complete with a cozy fireplace overlokking the gentle river and the majestic presence of eagles soaring overhead. Just 25 minutes to downtown La Crosse. Unwind and recharge as you step onto the expansive deck, where you'll be greeted by the soothing sounds of the flowing river. Breathe in the fresh air in the unparalleled beauty of nature.
4.98 out of 5 average rating, 47 reviews
Riverfront View
Need a weekend away with your spouse, your entire family or friends. 2 BR home located on the historic Mississippi River just north of De Soto, WI. The home is 26 miles from La Crosse, WI. A convenient place to stay while enjoying local attractions/events or spending time on the river. Enjoy fishing from personal dock, boating and a evenings by the campfire. NEAR train tracks. It goes by often DAY and NIGHT. You can’t see it from cabin but you can hear the horn and rumbling.
4.97 out of 5 average rating, 71 reviews
Summit View Cabin In The Woods
Enjoy the Summit View Cabin In The Woods. Located in the heart of the Driftless area. Centrally located between La Crosse ,WI-Prairie du Chien,WI-Viroqua WI and Lansing,Iowa. If you enjoy hunting, hiking , fishing , being on the river then this cabin will be close to all activities. Enjoy the hot tub in the fully screened in porch, have a fire in the smoke-less fire pit. Take an educational nature walk with a 15 tree ID species walk. Plenty of parking for boats/trailers.
5.0 out of 5 average rating, 11 reviews
Paradise Point sleeps 2 Hot Tub
1 bedroom 1 bath with loft. Cozy home where you can see Paradise. This memorable place is anything but ordinary. Views for miles of the Mississippi River, bluff tops and you can soar with the Eagles. What a place to relax in the newly added hot tub while you enjoy the view in what is call "God's Country". This is promised to be a one of a kind view. The Deck with comfortable outdoor seating Located in the heart of WIsconsin's Driftless Region.
4.96 out of 5 average rating, 162 reviews
De Soto Riverview Cabins #4
Cabin #4 is a two bedroom cabin, fully furnished with kitchen and bath, featuring two (2) queen beds. You'll love the exposed beams and vaulted ceilings. Max occupancy is 4 adults/children. Located in the village of DeSoto, WI. The area offers numerous activities including year round fishing, hiking, seasonal hunting, snowmobile trails, motorcycle riding, bicycling trails, wineries, breweries, Amish Bakeries.
4.95 out of 5 average rating, 21 reviewsPopular amenities for De Soto vacation rentals
Other great vacation rentals in De Soto

Bear Bluff Cabin / HOT TUB / EV Charge / Sleeps 10
5.0 out of 5 average rating, 10 reviews
River Cabin | Firepit, Sauna, Private Deck
4.94 out of 5 average rating, 50 reviews
Secluded cabin with hot tub in the driftless
4.73 out of 5 average rating, 141 reviews
Stonewall Suite 1 / 1st Floor / Sleeps 2
5.0 out of 5 average rating, 4 reviews
Bunkhouse on the Bluff / Fireplace / Sleeps 7
5.0 out of 5 average rating, 14 reviews
Bungalow on the Bluff / HOT TUB / Sleeps 4
5.0 out of 5 average rating, 4 reviews
Murph's: Cozy 3BR/2BA cabin w/ hot tub + fireplace
4.89 out of 5 average rating, 125 reviews
The Sunset River View- hot tub, fireplace Romantic
4.94 out of 5 average rating, 125 reviewsDestinations to explore
- Chicago Vacation rentals
- Minneapolis Vacation rentals
- Milwaukee Vacation rentals
- Omaha Vacation rentals
- Traverse City Vacation rentals
- Des Moines Vacation rentals
- Saint Paul Vacation rentals
- Downtown Chicago Vacation rentals
- Duluth Vacation rentals
- Sioux Falls Vacation rentals
- Grand Rapids Vacation rentals
- Saugatuck Vacation rentals





