Vacation rentals in De Soto

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Top-rated vacation rentals in De Soto

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
A clear blue swimming pool is framed by a spacious wooden deck. Umbrellas in red and blue provide shade for the nearby seating areas. The house is visible in the background, featuring large windows that open to the outdoor space.
Home in Urbandale
4.97 out of 5 average rating, 132 reviews

Big Groups/Pool/Hot tub/Large backyard/Fire Pit

Gather your group in this spacious 5BR, 3BA retreat made for connection and fun. After a day exploring, come back to the pool, hot tub, and sunroom dining. Inside, unwind in two cozy lounges or spark friendly competition in the arcade and game-filled garage. With room for 16, this home isn’t just a stay—it’s where family and friends celebrate, play, and make lasting memories together. Close to: 🏴󠁴5 mins to Get Air Trampoline Park ⛳ 10 minutes to Topgolf 🌆 20 minutes to Downtown Des Moines

Top guest favorite
Home in Clive
5.0 out of 5 average rating, 46 reviews

Modern Functional 5BR 3BA Ranch Home In Clive

This home offers blend of comfort cozy and functionality. Modern crafted ranch style offering over 3,500 square feet of luxury functionality and more. This home has 5 bedrooms 3 full baths 10’ ceilings spacious mudroom/laundry gourmet kitchen with a spacious island. Lower level has a large family room a bar area pool table/ping pong table table board games. Access to outdoor BBQ area with stairs leading to upper closed in deck. Basketball hoop Park on driveway garage & opposite side of street

Top guest favorite
A high wooden ceiling features exposed beams, creating a rustic atmosphere. A railing offers a view down to a living area with a neutral color palette, where a fireplace and decorative elements can be seen in the background.
Cottage in Redfield
4.99 out of 5 average rating, 139 reviews

Raccoon River Retreats

Come & experience the magic of this unique getaway,where the warmth of a renovated 1900's home meets the natural wonders of the Raccoon River. 30min from DSM,Ia.Whether you enjoy an adventure on the river of kayaking, paddle boarding, fishing,a peaceful moment along the biking trails,cozy up with a cup of coffee by the fireplace or a fire in the outdoor fire pit,our retreat has an idyllic setting to create lasting memories.A scenic landmark, local restaurant,Dairy shop & Dollar General are near

Top guest favorite
A well-furnished living area features two sofas and an accent chair arranged around a central coffee table. Natural light floods in through large windows, highlighting a cozy fireplace and elegant decor on the shelves. Wood flooring adds warmth to the inviting space.
Home in Urbandale
4.96 out of 5 average rating, 180 reviews

Sleeps 12 | Hot Tub | Air Hockey | 3.5 Baths

Bring the whole crew to this spacious 3-level Urbandale home — ideal for family reunions, group getaways, or Des Moines sports weekends. Soak in the year-round hot tub after a long day, then challenge everyone to air hockey in the walk-out basement rec room. Spread out across 4 bedrooms and 3.5 baths with fast fiber WiFi and 65" smart TVs in both living areas. The fenced backyard and quiet suburban street are perfect for kids and pets. Minutes from downtown Des Moines and the Jordan Creek Mall.

Top guest favorite
A cozy living room features a modern fireplace framed by white cabinetry and shelves displaying decorative items. A flat-screen TV is mounted on the wall. Comfortable seating includes a dark armchair and a tan sofa, with a light area rug covering the hardwood floor.
Home in Waukee
5.0 out of 5 average rating, 76 reviews

Home in Waukee

Bring the family or group of friends to this spacious 4bdrm, 3ba home. Enjoy the king suite, complete with an ensuite bath which includes a relaxing Jacuzzi Tub! Cook your favorite meals in the fully stocked kitchen. Pack light & utilize the W/D. Enjoy outdoor fun in the fenced in yard. Located in a family-friendly neighborhood. Located close to local restaurants and parks. Whether you're here for a weekend away or an extended stay, this retreat offers everything you need for a memorable stay.

Top guest favorite
A paved pathway leads through a lush green lawn, framed by a variety of trees. In the distance, a timber frame lodge is visible, surrounded by landscaped gardens and a backdrop of colorful autumn foliage.
Home in Adel
4.99 out of 5 average rating, 69 reviews

Timberpine Lodge - Escape to the Country

Escape to a stunning Iowa rural landscape and enjoy a peaceful getaway at this fantastic vacation rental. Hosting 4 bedrooms, 3.5 baths, and a well-appointed living space with a log-cabin feel, this home invites you to unwind with ease after days spent venturing down Raccoon River waters or cycling the Raccoon River Bike Trail. The lodge is an authentic timber frame structure. Step outside and listen to the breeze pass through trees, the chirps of seasonal birds, and calls of other wildlife.

Top guest favorite
A modern living room features a comfortable gray sofa and two brown accent chairs beside a stylish coffee table. A flat-screen TV is mounted above a sleek fireplace, with shelving displaying decorative items. Natural light filters in through the large windows, creating an inviting ambiance.
Home in Waukee
4.99 out of 5 average rating, 142 reviews

Waukee Guest House - Close to everything in DSM

Welcome to the Waukee Guest House! You will love calling this new, expanded ranch-style home your central Iowa home away from home. Located just minutes from I-80, our house is a 10-minute drive from Jordan Creek Mall in West Des Moines and 15 min. from downtown Des Moines and Wells Fargo Arena. You can access 4 bedrooms, 3 full baths, a large kitchen/dining area, and two beautiful living room spaces during your stay. We offer Smart TVs in every bedroom and living room space.

Guest favorite
Home in Van Meter
5.0 out of 5 average rating, 10 reviews

Designer 4BR-New Build! Giant TV, Great for Groups

This newly built Van Meter home offers 4.5 bedrooms, 3 bathrooms, and space for up to 10 guests — ideal for family travel, group getaways, sports teams, and corporate retreats. Private home theater with 86" screen, 50" Smart TVs in every bedroom, modern finishes, and a deck with stunning pond and sunset views. Minutes from I-80, Jordan Creek Mall, RecPlex, Downtown Des Moines, Winterset, Adel, and Waukee. Quiet, safe neighborhood — new build means no wear, just clean comfort!

Top guest favorite
A spacious living area features a modern design with a large sofa and two green accent chairs. A sleek entertainment unit with a fireplace is centered on the wall. Large windows provide natural light, enhancing the open and airy atmosphere.
Barn in Des Moines
5.0 out of 5 average rating, 175 reviews

8000sqft Barndo | Indoor Court + 2 Living Qtrs

Welcome to The Lodge on 3rd - a massive 8000 sq ft Barndominum. Nestled in the heart of Des Moines, Iowa, this stunning retreat offers the perfect blend of rustic charm and modern elegance. With 4 spacious bedrooms and a large loft, there is plenty of room for you and your guests to unwind in style. This property is next door to Luxury Living on Third. airbnb.com/h/luxurylivingonthird These combined properties are ideal for family reunions, etc. ***$200 Pet Fee***

Guest favorite
The two-story farmhouse features a white exterior and a welcoming front porch, adorned with potted plants. A staircase leads to the entrance, flanked by a neat lawn. An American flag is displayed, adding to the home's charm and character.
Home in Earlham
4.95 out of 5 average rating, 142 reviews

Friendly Quarters

This charming location is a farmhouse style home built in 1914. Easily found on the main street through town, a one block walk in any given direction will put you at the center of the city. A grocery story, eating establishments, gift shops and community center are conveniently located in the downtown area. Friendly Quarters operates as a non-profit organization to support the missions and ministries of Earlham Friends (Quaker) Church located right next door.

Top guest favorite
An open-plan living area is shown, featuring a comfortable gray sofa with orange pillows. A wooden dining table is accompanied by black chairs, while a ceiling fan adds to the airiness. Sliding barn doors lead to another room, and natural light enhances the inviting feel.
Home in Winterset
5.0 out of 5 average rating, 100 reviews

The Roost at Speckled Hen Farms.

Explore the Iowa countryside with this 70's ranch as your relaxing base camp. Situated on 5 acres of rolling hills in rural Madison County, Iowa, this centrally located homestead has something for every kind of traveler. The charming town of Winterset is just minutes away, as well the historic Covered Bridges, wineries, breweries, parks and more. Located next to Speckled Hen Farms farm store and Lone Oaks Farm, you can take in an occasional music event or class!

Guest favorite
A view of a charming farmhouse surrounded by vibrant pink flowers in full bloom. A white picket fence lines the flowerbed, while the house sits peacefully amidst a backdrop of lush greenery and clear blue skies.
Farm stay in Winterset
4.98 out of 5 average rating, 62 reviews

Entire farmhouse in the country

Just 10 minutes north of Winterset, stay in a Covered Bridge House. You’ll love visiting the historic bridges & John Wayne Birthplace Museum. Perfect for families and groups, enjoy relaxing at our newly renovated “modern farmhouse style” home. A quiet retreat, nestled in beautiful rolling hills. Built by Eli Cox family, renowned covered bridge builders. It’s a short 5 minute drive to local attractions: Winterset Cidery, Covered Bridges Winery & Guye Woods.

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