
Vacation rentals in De Soto
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Top-rated vacation rentals in De Soto
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Historic Home on 4 Acres - Hot Tub, Pool, Tiki Bar
Our 1948 vacation home is on 4 acres & boasts 3 bedrooms, 3 full baths, 2 half baths, Bridal Suite (4th bedroom), 70s TV/Game Room, Tiki Bar, & Children's Playroom. Outside we have a pool (guaranteed to be open 5/26 - 9/5) & hot tub (year round). Located 15min away from Downtown DSM & a mile away from a grocery store/restaurants. Up to 2 dogs allowed for an additional fee. ***Events/photo shoots are allowed with written permission only and will be an added fee. No events larger than 25 total.***
4.97 out of 5 average rating, 212 reviews
RARE Spacious Treehouse & Sauna Near Des Moines
Come home to luxury in nature in this spacious, double king-bed treehouse and sleep among the stars. Expansive views of rolling hills greet you as you sip your pour-over coffee on the wrap around balcony twenty feet above ground. Rain? No problem. Tuck away on the three-season screened-in porch to watch the iconic Iowa pink sunsets. Built with special touches including stained glass and intricate woodwork, this treehouse boasts warmth throughout and is sure to be a once-in-a-lifetime get-away.
4.99 out of 5 average rating, 104 reviews
Executive Living 2min to Jordan Creek 6 bed/5 bath
Welcome home! Enjoy almost 4000 sq feet of high end luxury living! > Best West Des Moines Location on Airbnb! Minutes to Jordan Creek & West Glen > 6 Bed - 5 bath > Beautiful full sized kitchen > Pool table & Wet Bar In basement > Oversized Master bedroom w/ 75" TV & master bathroom > Jetted soaking tub in master bath > 3 kings, 1 queen, 2 fulls and bunk bed w/ twin over full > Deck with bbq grill, patio furniture and gas firepit > Smart TV's in all rooms. 75" in Master and 65" in living room!
4.93 out of 5 average rating, 133 reviews
Modern Functional 5BR 3BA Ranch Home In Clive
This home offers blend of comfort cozy and functionality. Modern crafted ranch style offering over 3,500 square feet of luxury functionality and more. This home has 5 bedrooms 3 full baths 10’ ceilings spacious mudroom/laundry gourmet kitchen with a spacious island. Lower level has a large family room a bar area pool table/ping pong table table board games. Access to outdoor BBQ area with stairs leading to upper closed in deck. Basketball hoop Park on driveway garage & opposite side of street
5.0 out of 5 average rating, 46 reviews
Private lake, lodge & 23 acres south of Des Moines
Amazing, secluded 23 acres of property highlighted with a 6 BR lodge and your own PRIVATE lake. For the bike enthusiast, the famous 17 mile Great Western bike trail is located right at the driveway. For the kids or kid-at-heart, enjoy numerous activities & games: - basketball court - sand VB court - 6 kayaks - 2 ping pong tables - billiards table - air hockey - 2 foosball tables - numerous board & card games - ladder ball, bag toss Located <15 miles south of Des Moines/Jordan Creek Mall.
4.95 out of 5 average rating, 101 reviews
Raccoon River Retreats
Come & experience the magic of this unique getaway,where the warmth of a renovated 1900's home meets the natural wonders of the Raccoon River. 30min from DSM,Ia.Whether you enjoy an adventure on the river of kayaking, paddle boarding, fishing,a peaceful moment along the biking trails,cozy up with a cup of coffee by the fireplace or a fire in the outdoor fire pit,our retreat has an idyllic setting to create lasting memories.A scenic landmark, local restaurant,Dairy shop & Dollar General are near
4.99 out of 5 average rating, 139 reviews
Designer 4BR-New Build! Giant TV, Great for Groups
This newly built Van Meter home offers 4.5 bedrooms, 3 bathrooms, and space for up to 10 guests — ideal for family travel, group getaways, sports teams, and corporate retreats. Private home theater with 86" screen, 50" Smart TVs in every bedroom, modern finishes, and a deck with stunning pond and sunset views. Minutes from I-80, Jordan Creek Mall, RecPlex, Downtown Des Moines, Winterset, Adel, and Waukee. Quiet, safe neighborhood — new build means no wear, just clean comfort!
5.0 out of 5 average rating, 10 reviews
8000sqft Barndo | Indoor Court + 2 Living Qtrs
Welcome to The Lodge on 3rd - a massive 8000 sq ft Barndominum. Nestled in the heart of Des Moines, Iowa, this stunning retreat offers the perfect blend of rustic charm and modern elegance. With 4 spacious bedrooms and a large loft, there is plenty of room for you and your guests to unwind in style. This property is next door to Luxury Living on Third. airbnb.com/h/luxurylivingonthird These combined properties are ideal for family reunions, etc. ***$200 Pet Fee***
5.0 out of 5 average rating, 175 reviews
Friendly Quarters
This charming location is a farmhouse style home built in 1914. Easily found on the main street through town, a one block walk in any given direction will put you at the center of the city. A grocery story, eating establishments, gift shops and community center are conveniently located in the downtown area. Friendly Quarters operates as a non-profit organization to support the missions and ministries of Earlham Friends (Quaker) Church located right next door.
4.95 out of 5 average rating, 142 reviews
The Roost at Speckled Hen Farms.
Explore the Iowa countryside with this 70's ranch as your relaxing base camp. Situated on 5 acres of rolling hills in rural Madison County, Iowa, this centrally located homestead has something for every kind of traveler. The charming town of Winterset is just minutes away, as well the historic Covered Bridges, wineries, breweries, parks and more. Located next to Speckled Hen Farms farm store and Lone Oaks Farm, you can take in an occasional music event or class!
5.0 out of 5 average rating, 100 reviews
Kim's Kottage on the RRVT, in Minburn, IA.
This home is perfect for the Cycling Enthusiast, a couple, family or small group of friends. This fully furnished cozy 2 bedroom home is sure to please. Located 1 block from the Raccoon River Valley Bike Trail (75 mile paved loop), 15 minutes from I-80 and 30/40 minutes from the State's Capital City of Des Moines, Minburn is the "Small Town with a Big Heart". There are two City Parks, an outdoor historical roller skating rink & 2 Rest/Bars.
4.96 out of 5 average rating, 384 reviews
Cheerful 3 bedroom home in a quiet small town
Come relax with your family in this peaceful and stylish 3 bedroom home. Bring your bikes and you'll have easy access to the Raccoon River Valley Trail. You can spend quality time together playing games and ping pong, or just sit outside and relax in the quiet small town atmosphere. You can make your own home cooked meal in the fully equiped kitchen or you can try the local restaurants.
4.93 out of 5 average rating, 149 reviewsPopular amenities for De Soto vacation rentals
Other great vacation rentals in De Soto

A farm get-a-way
4.97 out of 5 average rating, 32 reviews
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Fresh Remodel! Whole House Getaway Near DSM!
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Family Oasis
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Graceland Acreage w/ Party Barn!
4.78 out of 5 average rating, 45 reviews
Private 7-Acre Estate with Hot Tub & Pond
5.0 out of 5 average rating, 27 reviews
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