
Vacation rentals in Clayton
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Top-rated vacation rentals in Clayton
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Cave Courtyard Guest Studio
The Cave Courtyard Guest Studio. A relaxing getaway located on the ground floor of an 1848 historic building just 1 block from the Mississippi River and unique shops and eateries. Sleeps 4 with a queen bed and daybed with pull out trundle, private entrance, private bath with shower, kitchenette with microwave and mini fridge, internet, cable tv and air-conditioning. There is also a private courtyard located below unique cliff side caves. Some food items are also supplied. Adults only-no pets.
4.96 out of 5 average rating, 334 reviews
Larsen Rustic Secluded Log Cabin W/Outdoor Hot Tub
Secluded cabin hike the trails to the cave and ponds. Close to trout fishing stream or Mississippi for fishing. Bring you UTV and ride the private trails $30 per driver and 10 per passenger or rent an UTV 300.00 per day Approx 15 miles from Priarie Du Chein, close to canoe outposts for the Kickapoo, Wisconsin river. Has a gas ,charcoal grill,fire pit, pool table, fooseball, ping pong table. Smart TV Private UTV trails are closed Oct 15th thru mid Jan for hunting. Access to public UTV trails.
4.79 out of 5 average rating, 473 reviews
The Bunk House
Book your stay with The Bunk House! Great for large groups, cozy weekends or family getaways. Features include free WiFi, TV/DVD player/DVDs and board games available, fully furnished kitchen, bathrooms, extra makeup stations and free laundry. The Bunk House is conveniently located within walking distance of beautiful downtown Prairie Du Chien~Great bars, restaurants, shopping, farmers/flea markets, water fun, historical sites and so much more. I’d love to help make your stay a memorable one!
4.93 out of 5 average rating, 189 reviews
McGregor Manor Victorian Getaway
Welcome to our beautiful Victorian home located in the quaint town of McGregor, Iowa. Our 2,800 sq. ft. home was built during McGregor's early years as a Mississippi River boom town. Attractions include antiquing, biking, fishing, hunting, hiking and boating! We're a short drive from Pike's Peak, Effigy Mounds and Prairie du Chien. All four bedrooms on the 2nd floor of the home include a private bath, providing comfort and privacy for each member of your group. Fully furnished and decorated.
4.94 out of 5 average rating, 245 reviews
River Bluff Retreat-Hot tub & game room
Relax with the whole family at this peaceful retreat just 5 miles from historic Guttenberg, Iowa. Situated on a bluff overlooking the majestic Mississippi River, you'll love the amazing view. This private property offers plenty of space with room for your boats and ATV's. Gather in the large game room, or spread out across multiple living areas. Enjoy the high-speed Starlink internet and complimentary access to YouTube TV and NFL Network. This is the perfect getaway for groups up to 13.
4.95 out of 5 average rating, 43 reviews
The Great River Retreat
Located in the heart of McGregor and within walking distance of antique shopping, local eateries and the Mississippi River. An outdoor enthusiast dream you can enjoy biking, fishing, hunting, hiking and boating all within miles at one of the many local parks; or try your hand at the local casino. Whether a weekend getaway or a long-term stay we welcome you to a historic 3-bedroom 1.5 bathroom home with ample living space, including a laundry room and fully stocked kitchen with a coffee bar.
4.94 out of 5 average rating, 17 reviews
Hayden's Hideout
Hayden's Hideout apartment is just two blocks from the river on Schiller Street and within walking distance of everything you need in downtown Guttenberg! Completely overhauled in 2020 with central air, furnace and fiber internet from Alpine Communications. Fully furnished private bathroom and kitchen. Adults only, no pets and no smoking. Conveniently located 150 feet from the Guttenberg Brewing Company where they are now serving food! Including food trucks every Thursday and Saturday!
4.91 out of 5 average rating, 92 reviews
Cozy Apartment Steps from the Mighty Mississippi
Disconnect from the daily grind and enjoy a getaway in this welcoming one bedroom apartment, steps away from the Mighty Mississippi. Located in Clayton, Iowa, Located within walking distance of two delicious restaurants and a boat launch., and only 1/2 hour from the Casino Queen, local wineries, Pikes Peak State Park, as well as the historic communities of Elkader, IA and Prairie Du Chien, WI. Need more space? I also offer a two bedroom apartment: www. airbnb. com/rooms/43979345
4.94 out of 5 average rating, 179 reviews
Paradise Point sleeps 2 Hot Tub
1 bedroom 1 bath with loft. Cozy home where you can see Paradise. This memorable place is anything but ordinary. Views for miles of the Mississippi River, bluff tops and you can soar with the Eagles. What a place to relax in the newly added hot tub while you enjoy the view in what is call "God's Country". This is promised to be a one of a kind view. The Deck with comfortable outdoor seating Located in the heart of WIsconsin's Driftless Region.
4.96 out of 5 average rating, 162 reviews
Clayton Riverway House~ River front home
Sit back and relax in a home that is directly on the Mississippi River in Clayton, Iowa! Enjoy watching the trains, barges and river traffic, fishing off of the private or public dock, or spending time with your friends and family in this quaint river town. Northeast Iowa has many activities to enjoy, such as boating, fishing, hiking, hunting, antiquing. Riverway House is the perfect place to stay while enjoying the beauty of Clayton County.
4.98 out of 5 average rating, 113 reviews
Mississippi Retreat: Scenic Views + Unique History
Discover the charm of this historic home, originally the Clayton Savings Bank built in 1915, now transformed into a spacious and inviting retreat just steps from the Mississippi River. With its preserved original bank vault, this home offers a one-of-a-kind blend of history and comfort. Enjoy breathtaking views of the river and surrounding bluffs from the large living area, which boasts high ceilings and plenty of natural light.
4.86 out of 5 average rating, 7 reviews
Valley Mills Miller's Cottage
Welcome to Valley Mills Miller's Cottage, where the beauty of "Mother Nature" surrounds you. Built six years after Iowa became a state in 1847, it is located in a remote picturesque valley containing Buck Creek Trout Stream. It is completely surrounded by wooded Bluffs, known as "Cold Slopes". With its two acre park like area, it is an ideal place for families to let their Kids/pets freedom to roam.
4.7 out of 5 average rating, 158 reviewsPopular amenities for Clayton vacation rentals
Other great vacation rentals in Clayton

Wandering Warriors Retreat
4.95 out of 5 average rating, 19 reviews
Bloody Run Retreat
4.95 out of 5 average rating, 73 reviews
Historic Charm in the Heart of McGregor, Iowa
4.97 out of 5 average rating, 39 reviews
The Lakeside Inn
4.9 out of 5 average rating, 10 reviews
River Trails Cottage
5.0 out of 5 average rating, 66 reviews
Suite 1 - Lydia's Loft
4.97 out of 5 average rating, 29 reviews
Grandma’s Guttenberg Getaway
5.0 out of 5 average rating, 30 reviews
R-Lodge Getaway!
4.98 out of 5 average rating, 42 reviewsDestinations to explore
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