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Vacation rentals in Chepo

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Chepo

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite
Tiny home in Islas Maqui
5.0 out of 5 average rating, 12 reviews

Overwater Paradise Cabin| AnsuBirya | San Blas |

🌴 Stay in a traditional waterfront hut in the heart of the paradise-like San Blas archipelago. Surrounded by a turquoise lagoon, white beaches, and palm trees, it offers a unique getaway away from the crowds and mass tourism. Spend your days snorkeling, swimming, and exploring uninhabited islands with our kayak, which is provided with the cottage, and spend your evenings admiring the spectacular Caribbean sunsets. Indulge in seafood from our top chef, Ibin. The offer includes 3 meals a day in the restaurant.

Superhost
Apartment in Panama City
4.92 out of 5 average rating, 169 reviews

Apto 4 min from Tocumen Airport | 24-hr check-in

Layover in Panama? Stay where everything is easy and comfortable Just 4 minutes from Tocumen International Airport – perfect for early flights or quick stopovers A modern, comfortable, and secure apartment with: • Fast WiFi and air conditioning • Smart lock and flexible check-in • 24/7 security • Pool, gym, and fully equipped kitchen • Steps from the ITSE Metro station Ideal for layover travelers, curious tourists, or business trips. 🌴 Just arrive — everything’s ready for you. We’ll be waiting!

Guest favorite
A serene river flows beside the property, surrounded by lush greenery and rocky formations. Trees and tropical plants frame the scene, while small cascades create a gentle noise, enhancing the tranquil atmosphere of the natural landscape.
Cottage in Panama City
4.92 out of 5 average rating, 122 reviews

Round House River Dreams Cerro Azul

Get away from it all and relax in an idyllic tropical rustic retreat set beside a beautiful river with small cascades in the mountains of Cerro Azul. This spacious 2-story, one bedroom home is ideal for couples, small families or groups, with ample space to sleep 6 to 7 people. The property lies within Charges National Park with all its tropical flora and fauna, blue butterflies, hummingbirds, waterfalls and walking trails at your doorstep. Come experience this unique vacation home destination.

Top guest favorite
Place to stay in Panama City
5.0 out of 5 average rating, 25 reviews

Casa Condal - Your Luxury Retreat in Cerro Azul

Birdwatching • Romantic Getaway • Remote Work Escape the city. Breathe pure mountain air. Reconnect with nature. Casa Condal - private, modern, sustainable and regenerative hospitality inside Chagres National Park WiFi 65" Smart TV. Sound Bar Self check-in Private parking Fully equipped kitchen 220mts. private trail Deck-Mirador + FirePit, panoramic view of the mountains and valley King bed + Full size sofa bed BBQ Wheelchair accessible 40 min from Tocumen Airport. 1 hr from Panama city.

Guest favorite
Boat in San Blas Islands
5.0 out of 5 average rating, 8 reviews

Private Catamaran live on board

Welcome aboard catamaran Yoyo, your floating home in the San Blas Islands. Your stay includes breakfast and snacks, with an optional meals and drinks package for USD 80 per person per day. For stays of 5 or more days, meals and drinks are included. Spend your days swimming, snorkeling, fishing, exploring hidden beaches, or relaxing on deck, and your nights unwinding under the stars. Experience the perfect blend of adventure, freedom, and laid-back island living with all the comfort you need.

Superhost
An aerial view showcases a rustic cottage surrounded by lush palm trees, located near a sandy beach. The gentle waves of the ocean are visible, along with several red-roofed structures nestled within the greenery, creating a serene coastal atmosphere.
Cottage in Palenque
4.87 out of 5 average rating, 95 reviews

Beachfront House in Caribbean sandy beach

Enjoy this rustic and cozy cottage with its almost private beach surrounded by beautiful palm trees along the whole area. With 2 oceanview bedrooms, 2 full bathrooms and a third bedroom in a mezzanine. Has a patio with a built in uruguayan parrilla, ideal for BBQs. Step in beautiful white sand and bath in crystal clear water. Coconut breakfasts watching the sunrise become a routine in this paradise. - This is a rural setting. Not a 5 star hotel. Insects and small animals can be around.

Guest favorite
A stone pathway leads through lush tropical foliage toward a welcoming entrance. Tall trees and vibrant greenery frame the path, creating a serene approach to the property, which is partially visible in the background, surrounded by nature's tranquility.
Home in Panama City
4.97 out of 5 average rating, 88 reviews

Mountain Retreat

Relax and unwind at this peaceful property nestled on two hectares of lush tropical vegetation surrounded by the sights & sounds of nature. Located at Panama's Blue Mountain(Cerro Azul), 30 kilometres from Panama City. This cozy & comfortable home is equipped with modern amenities & chic decorative touches. It consists of a main house with 2 bedrooms & a 2 bedroom cottage. It has a spacious terrace, pool & jacuzzi overlooking Panama City. The property also boasts its own spring water well

Top guest favorite
Cabin in Panama City
4.9 out of 5 average rating, 21 reviews

Casita Pino Azul, Natural Escape + Jacuzzi + Relax

Enjoy a cozy experience among mountains, birds and fresh air in Cerro Azul. Relax with the whole family in this accommodation where tranquility is breathed. Surrounded by nature and tranquility. Ideal for couples or families looking to disconnect without leaving the city. It has comfortable beds, equipped kitchens, a Jacuzzi, WiFi and a private terrace. Perfect for relaxing, sharing with family, or a weekend getaway. Located in a safe area, with easy access and cool climate.

Top guest favorite
A sailing yacht rests in clear blue waters near a sandy beach bordered by palm trees. Small boats can be seen cruising nearby, and a colorful structure is visible on the shore, surrounded by lush greenery and the expansive ocean.
Boat in San Blas Islands
5.0 out of 5 average rating, 24 reviews

73ft Family Sailing Yacht, Unique & Very Spacious

Spend your family vacation on "Sailing Renaissance", a unique 73feet (22m) long, the largest sailing yacht available, with Professional Captain and Chef included. We have two kids onboard (9 & 11) All meals are included. Max 4 guests If you are looking for comfort, privacy, amazing experience, excellent food and great services, this is the right place. This is a Private Yacht, there will be only you and the crew. We have all the watertoys you need and High Speed Internet.

Superhost
A tranquil dipping pool is framed by lush greenery, featuring white loungers and a large umbrella for shade. The pool area exudes a serene vibe with vibrant bougainvillea in the background, enhancing the inviting outdoor space.
Home in Taboga Island
4.94 out of 5 average rating, 222 reviews

Casa Rosie - Dream Home on Tabogá Island

Casa Rosie is a gorgeous villa on Taboga island with an intimate vibe and spectacular views of the ocean. The perfect place for couples, small groups, and families to unwind and make magical memories! . With great wifi, fully equipped kitchen, 3 inviting bedrooms, and a spacious yet personal feel… Casa Rosie is your home away from home. Included in every stay is free pick up and drop off to the ferry terminal - please let us know the details of your arrival.

Guest favorite
Cabin in Panama City
4.93 out of 5 average rating, 92 reviews

The Crystal House: Luxury Modern Wood Cabin

Create unforgettable memories at this unique and family-friendly place. Stay in a cabin in the middle of Chagres National Park, 50 minutes from the city. You can be in contact with nature while having all the comforts of a luxury accommodation. With one of the best views of the city, you can enjoy a good barbecue, a nap in the hammock, or a meeting around the fireplace. Relax and connect with the beautiful green of Panama. We'll be waiting for you!

Top guest favorite
Cottage in Panama City
4.95 out of 5 average rating, 40 reviews

Cerro Azul Mountain Retreat un hogar mágico.

Enjoy every corner and luxury in this spacious house with 6 rooms with airs and 6 bathrooms. The perfect terrace to relax outdoors, while the ideal dining room to share special moments with your loved ones. The greenhouse is an oasis of fresh ingredients, ready to inspire delights. We have a new deck and jacuzzi ready to enjoy allowing you to connect with nature and beautiful sunsets. It has a game room, soccer pool table and a/ac

Popular amenities for Chepo vacation rentals