
Vacation rentals in Chepo
Find and book unique accommodations on Airbnb
Top-rated vacation rentals in Chepo
Guests agree: these stays are highly rated for location, cleanliness, and more.

Apto 4 min from Tocumen Airport | 24-hr check-in
Layover in Panama? Stay where everything is easy and comfortable Just 4 minutes from Tocumen International Airport – perfect for early flights or quick stopovers A modern, comfortable, and secure apartment with: • Fast WiFi and air conditioning • Smart lock and flexible check-in • 24/7 security • Pool, gym, and fully equipped kitchen • Steps from the ITSE Metro station Ideal for layover travelers, curious tourists, or business trips. 🌴 Just arrive — everything’s ready for you. We’ll be waiting!

Round House River Dreams Cerro Azul
Get away from it all and relax in an idyllic tropical rustic retreat set beside a beautiful river with small cascades in the mountains of Cerro Azul. This spacious 2-story, one bedroom home is ideal for couples, small families or groups, with ample space to sleep 6 to 7 people. The property lies within Charges National Park with all its tropical flora and fauna, blue butterflies, hummingbirds, waterfalls and walking trails at your doorstep. Come experience this unique vacation home destination.

Casa Condal - Your Luxury Retreat in Cerro Azul
Birdwatching • Romantic Getaway • Remote Work Escape the city. Breathe pure mountain air. Reconnect with nature. Casa Condal - private, modern, sustainable and regenerative hospitality inside Chagres National Park WiFi 65" Smart TV. Sound Bar Self check-in Private parking Fully equipped kitchen 220mts. private trail Deck-Mirador + FirePit, panoramic view of the mountains and valley King bed + Full size sofa bed BBQ Wheelchair accessible 40 min from Tocumen Airport. 1 hr from Panama city.

Private Catamaran live on board
Welcome aboard catamaran Yoyo, your floating home in the San Blas Islands. Your stay includes breakfast and snacks, with an optional meals and drinks package for USD 80 per person per day. For stays of 5 or more days, meals and drinks are included. Spend your days swimming, snorkeling, fishing, exploring hidden beaches, or relaxing on deck, and your nights unwinding under the stars. Experience the perfect blend of adventure, freedom, and laid-back island living with all the comfort you need.

Beachfront House in Caribbean sandy beach
Enjoy this rustic and cozy cottage with its almost private beach surrounded by beautiful palm trees along the whole area. With 2 oceanview bedrooms, 2 full bathrooms and a third bedroom in a mezzanine. Has a patio with a built in uruguayan parrilla, ideal for BBQs. Step in beautiful white sand and bath in crystal clear water. Coconut breakfasts watching the sunrise become a routine in this paradise. - This is a rural setting. Not a 5 star hotel. Insects and small animals can be around.

Mountain Retreat
Relax and unwind at this peaceful property nestled on two hectares of lush tropical vegetation surrounded by the sights & sounds of nature. Located at Panama's Blue Mountain(Cerro Azul), 30 kilometres from Panama City. This cozy & comfortable home is equipped with modern amenities & chic decorative touches. It consists of a main house with 2 bedrooms & a 2 bedroom cottage. It has a spacious terrace, pool & jacuzzi overlooking Panama City. The property also boasts its own spring water well

The Crystal House: Luxury Modern Wood Cabin
Crea recuerdos inolvidables en este alojamiento único e ideal para familias. Quédate en una cabaña en medio del Parque Nacional Chagres a 50 minutos de la ciudad. Podrás estar en contacto con la naturaleza contando con todas las comodidades de un alojamiento de lujo. Con una de las mejores vistas a la ciudad puedes disfrutar de una buena barbacoa, una siesta en la hamaca o una reunión alrededor de la chimenea. Relájate y conéctate con el lindo verde de Panamá. Te esperamos!

Casa Rosie - Dream Home on Tabogá Island
Casa Rosie is a gorgeous villa on Taboga island with an intimate vibe and spectacular views of the ocean. The perfect place for couples, small groups, and families to unwind and make magical memories! . With great wifi, fully equipped kitchen, 3 inviting bedrooms, and a spacious yet personal feel… Casa Rosie is your home away from home. Included in every stay is free pick up and drop off to the ferry terminal - please let us know the details of your arrival.

Casco Antiguo Apartment with Balcony & Stone Wall
Elegante apartamento en el corazón de Casco Antiguo. Disfruta de un espacio colonial con paredes de piedra expuesta, iluminación cálida y un encantador balcón con vista a calles vibrantes. Ubicado en Avenida B, a pasos de restaurantes, cafeterías, rooftop bars y lugares históricos. Capacidad para hasta 5 huéspedes. Perfecto para vivir la cultura y energía de Casco Viejo. Debido al ambiente animado del área, puede escucharse ruido nocturno los fines de semana.

Tropical Haven with Pickleball/Yoga Platform
Tropical "open-concept" Airbnb, with a private pool and yoga/meditation platform, located in a typical village, 20 minutes outside the hustle of Panama City, Panama - Central America. This modern contemporary tropical home is located in the hills of Caceres on a 5 acre finca full of tropical trees, birds, and a manicured grounds. Outdoor gas and charcoal barbecue off of back patio with vertical herb garden for perfect relaxation retreat.

Altos de Cerro Azul | AC, Full Kitchen, 2 Rooms
Some escapes stay with you. This is one of them. Located in the highlands of Altos de Cerro Azul, this modern mountain home is perfect for disconnecting without giving up comfort. Wake up to panoramic views, breathe cooler air, and enjoy true peace. Ideal for couples, small families, or remote workers seeking a calm retreat in nature. Traveling as a couple? Ask us about a special rate. No pets allowed.

Flexible check-in • 10 min from the airport WiFi
Perfect for layovers, night or early flights, and short stays. Stay just 10 minutes from Tocumen Airport • Easy and flexible self check-in 🛏️ Private studio for up to 2 guests ❄️ A/C 📶 Fast Wi-Fi 🚿 Shower with hot water 🍳 - Stocked kitchen 🔒 Secure residential community 🚗 Airport transportation available (reservation required) Ideal for travelers in transit, couples or short, hassle-free stays.
Popular amenities for Chepo vacation rentals
Other great vacation rentals in Chepo

Entire Villa with pool in front of beach!

Private parking & rooftop | Studio Casco Center

The Scape Fountain

Walk to Everything | Luxury Stay in Casco Viej

#1 Cabin on the Lake Cerro Azul

Overwater Paradise Cabin| AnsuBirya | San Blas |

Eco Sailing in Paradise Private - All inclusive

Luxury Designer Apt Casco Balcony + Rooftop Pool
Destinations to explore
- Panama City Vacation rentals
- Cahuita Vacation rentals
- Coveñas Vacation rentals
- Puerto Viejo de Talamanca Vacation rentals
- Bocas del Toro Province Vacation rentals
- San Andrés Vacation rentals
- Rio Hato Vacation rentals
- Boquete Vacation rentals
- El Valle Vacation rentals
- Valle de Antón Vacation rentals
- Nueva Gorgona Vacation rentals
- Puerto Jiménez Vacation rentals





