Guesthouse vacation rentals in Suwannee River

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Top-rated guesthouse rentals in Suwannee River

Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

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Guest favorite

The exterior of a charming guest house is illuminated by soft outdoor lights, highlighting its blue siding and white trim. A covered porch extends from the entrance, while potted plants line the pathway, set against a backdrop of trees and an open lawn.

Guesthouse in Gainesville

4.88 out of 5 average rating, 219 reviews

Sunflower Acres Cottage

Cute, cozy, freshly remodeled, private guest house on a beautiful 5 acre farm. Enjoy your own backyard herb garden with privacy fence, picnic table and fire pit. New kitchen with gas stove, microwave, toaster oven, coffee-maker, and dining area perfect for enjoying meals. The bedroom is equipped with a smart TV, queen bed, & extra blankets. This country getaway is near the University of Florida (12 miles), Blue Springs (21 miles) Ginnie Springs (24 miles), and historic High Springs (15 miles).

Guest favorite

A light-filled living area features a soft gray sofa and two blue accent chairs, complemented by a small coffee table. A television is positioned on a console with a decorative item, while a large area rug adds texture to the wood-like flooring.

Guesthouse in Lake City

4.96 out of 5 average rating, 112 reviews

Elegant 2BR Private Cottage • 2 min from I-75/US90

This 2 BR/1 BA newly constructed Guesthouse is situated in an upscale neighborhood in Florida's gateway city. During your visit you have all of the amenities of home including a well-equipped kitchen, washer/dryer, and a private patio w/ a gas grill. Relax and enjoy the serenity of the surroundings or explore the shopping and restaurants of Lake City only a 5 minute drive away. 2 miles from I-75; 5 miles from the sports/softball complex; 14 miles from Itchetucknee Springs State Park & rivers.

Top guest favorite

The exterior of the loft showcases a charming A-frame structure, accentuated by wooden beams and a warm glow from the illuminated windows. Soft string lights create an inviting atmosphere around the pathway, which is framed by lush greenery and leads to a shared firepit.

Guesthouse in Gainesville

4.96 out of 5 average rating, 241 reviews

Walk to UF! Historic King Bed Loft w/ Private Deck

If you are visiting Gainesville, look no further than Camellia Loft. This historic gem was built in 1924 and has been freshly renovated to bring it into the modern era. Enjoy the birdsong and majestic trees from your private deck overlooking the backyard—or relax inside as light streams through the loft's massive skylights. Only 0.5 miles to UF campus and exactly 1 mile to the stadium, you can easily walk to campus or games. Unwind by the shared fire pit or enjoy cooking on the grill

Top guest favorite

A well-appointed sleeping area features a spacious bed dressed in light gray bedding, flanked by two bedside tables with stylish lamps. Colorful wall art complements the space, while natural light streams through several textured windows, enhancing the tranquil ambiance.

Guesthouse in Gainesville

4.97 out of 5 average rating, 566 reviews

Renovated Private Studio - Walking Distance to UF

NEWLY RENOVATED - Enjoy your Gainesville stay in this mid-century modern studio 0.5 miles from UF and 2 miles from UF and HCA hospitals. No detail was overlooked in this beautifully designed detached guest house with an abundance of natural light, upscale finishes, and endless amenities - kitchenette, mini fridge/freezer, smart TV, and more! This conveniently located private and quiet space in the heart of Gainesville is perfect for anyone visiting for just one night or a few weeks.

Guest favorite

A rustic cabin is nestled among trees, featuring a spacious front porch with a wooden railing. Two kayaks, one red and one orange, rest on the ground nearby. The structure has multiple windows allowing natural light inside, complemented by a sloped metal roof.

Guesthouse in Fort White

4.98 out of 5 average rating, 127 reviews

Adorable cozy cabin near North Florida Springs

Keep it simple at this peaceful cabin….Centrally-located to Itchetucknee Springs, Ginny Springs, Poe Springs, Blue Springs, Santa Fe River, Suwannee River. This area is popular for diving , snorkeling, boating, fishing, kayaking, tubing and hiking or just relaxing with nature. Full kitchen, living room and separate bedroom with a comfortable queen bed and walk-in closet. A large bathroom with walk-in shower. Wi-fi throughout. 42” smart tv in living room, 32” smart tv in bedroom.

Top guest favorite

The spacious living area features a comfortable sectional sofa in shades of gray, with decorative pillows for added comfort. Large windows allow natural light to stream in, with views of the surrounding greenery. A coffee table sits in front of the sofa, complemented by a dining table visible in the background.

Guesthouse in Archer

4.95 out of 5 average rating, 176 reviews

Your own private space of peace and quiet.

Keep it simple at this peaceful and centrally-located place. While being only 15 miles from the nightlife of downtown Gainesville, this is country living at it best. With no street lights the stars are bright and easily counted. The mornings are bright and full of the music of bird songs. The cute 2 bedroom apartment (one double bed, two single beds) is on the SECOND FLOOR. It is easy to get lost in the whisper of the trees. This is a place to rest your soul and unwind.

Guest favorite

A two-story black wooden structure is depicted, featuring a spacious balcony adorned with seasonal decorations. Stairs lead to the upper level, and a covered area with parking is visible below. Surrounding greenery includes tall trees, enhancing the natural setting.

Guesthouse in Lake City

4.88 out of 5 average rating, 1,077 reviews

Studio loft/ kitchenette/porch/bath

3 Miles from I75 exit 414 .studio apartment w/ porch over barn. Fire pit with wood available. Grill. Hammock swings under oaks. Stalls available. Close to riding/hiking trails in O'leno State Park. Close to springs for tubing/kayak/canoe. Ichetucknee Spring State Park, Ginny Springs, ++. Also 15 minutes from Santa Fe River and paddling/kayak/canoe rentals . Diving excursions available in High Springs. Quiet setting w/ pastures and grand daddy oaks.

Guest favorite

A well-appointed studio apartment features an open layout with a combined kitchen and living area. Warm wood tones mingle with soft white walls, while leather seating surrounds a coffee table. A spacious bed with crisp linens is positioned near large windows, allowing natural light to fill the space.

Guesthouse in Jacksonville

4.96 out of 5 average rating, 255 reviews

Avondale Studio

Located in Avondale, Jacksonvilles historic district, this Garage Studio offers everything one needs for a getaway or a business trip. Walking distance to the Shoppes of Avondale. There are multiple restaurants/bars/outdoor cafe dining all within walking distance in either direction. The 2nd story garage apartment offers a balcony with views into Boone Park. Fully renovated in 2021 offering a full kitchen and bathroom. You have a private parking space as well.

Guest favorite

A charming exterior features a light-colored wooden panel house surrounded by greenery. Pink azalea flowers bloom near the entrance. A wooden deck with a lattice design provides outdoor seating and accessibility, situated alongside a paved area leading up to the building.

Guesthouse in O'Brien

4.84 out of 5 average rating, 522 reviews

River Retreat

In the heart of Florida's cave diving region. Located right on the Suwannee River. Near by attractions; Royal Spring with Boat Ramp; 4 miles; Little River Spring; 8 miles;Troy Spring; 17 miles; Blue Hole Spring; 20 miles; Ichetucknee Spring; 22 miles; . As of now, the dock and stairs going down to the river are under re-construction. But can still get down to the river. I have 3 large dogs, let me know when you might arrive. So I can have them inside.

Top guest favorite

The exterior of the studio features a welcoming entryway with a wooden deck bordered by tropical plants. Light green shutters frame the door, while a shaded pathway leads to the entrance, invoking a serene atmosphere enhanced by natural greenery.

Guesthouse in St. Augustine

4.96 out of 5 average rating, 499 reviews

Newly Renovated, Clean, Private, Studio

Aunt Suzie's Hideaway. Experience St. Augustine like a local. Fun, relaxing, tropical, historic, magical. Bring your bike, board, boat, or kayak. Safe, quiet neighborhood, walk, bike, fish or picnic along the intracoastal waterway and marsh. 1 mile to Shands Flagler Hospital, 4 miles to downtown historic district and 5 miles to the beach and Amphitheater. Small fully equipped kitchen, queen bed, large bathroom, sitting area, dining or worktable.

Top guest favorite

A shaded seating area is featured in front of a charming blue cabin. A small round table is accompanied by two lightweight chairs, topped with a decorative umbrella. Surrounding greenery enhances the peaceful outdoor setting.

Guesthouse in Trenton

4.88 out of 5 average rating, 173 reviews

Springs capital of the world

Secluded, peaceful, country property in the heart of springs country. Come relax, enjoy the peace and quiet and the bright stars. This cabin offers everything you need. This is our farm where we have free roaming chickens, dogs and cats. Your well behaved small pets are more than welcome to join you during your visit. There are many springs nearby, all within 10-30 minutes away. Escape from the city and enjoy the tranquil country life.

Top guest favorite

A two-story, yellow house is set among lush greenery, showcasing a spacious driveway covered with pine straw. A car is parked under a shelter attached to the structure, and the surroundings exhibit mature trees and natural landscaping.

Guesthouse in Micanopy

4.93 out of 5 average rating, 175 reviews

Private bed and bath above detached garage.

Close to Paynes Prairie Preserve State Park, Micanopy's unique downtown and a short easy drive to UF campus. North of Micanopy on Highway 441 across from Lake Wauberg. A common private driveway from the highway leads up to our two story home and two story detached garage. Uber not a good option. Good for couples, solo adventurers, and business travelers; and great for Gator friends and fans. Smoke free and no pets please.