Vacation home rentals in South America

Find and book unique vacation home rentals on Airbnb

Top-rated vacation home rentals in South America

Guests agree: these vacation home rentals are highly rated for location, cleanliness, and more.

0 of 0 items showing

1 of 3 pages

Guest favorite

The exterior showcases a modern two-story building featuring a mix of dark siding and natural stone accents. Sturdy stairs lead to the upper entrance, while large windows on both levels provide ample natural light. A serene landscape of hills is visible in the background.

Vacation home in El Chaltén

4.9 out of 5 average rating, 136 reviews

House 3, BUENAVISTA CHALTEN, MOUNTAIN HOUSES.

Brand new, high quality apartment. 2 bedrooms, fully equipped and 50 square meters. Living room, dining room, and full kitchen with quality supplies and appliances (refrigerator, toaster, stove with oven, microwave, electric kettle, etc.) and 2 giant windows in the kitchen and living room with one of the best views of the town. Each bedroom has a box spring and quality linens, with a choice of beds. 3 smart TVs, Wi-Fi, etc. Very good location, meters from the beginning of trails and close to downtown.

Top guest favorite

A light-filled living area features a spacious sectional sofa arranged around a coffee table, accompanied by two round ottomans. Soft, neutral tones are present throughout, with wall art depicting serene beach scenes. The loft area is visible above, creating an open and airy feel.

Vacation home in CARTAGENA

4.98 out of 5 average rating, 120 reviews

Brand New 1 BR Luxury Suite/Loft Historic Center

1 BR Loft Suite in the heart of Cartagena inspired by some of the finest 5 star Hotels in the world. Located inside the walls of the old city, within walking distance to shops, entertainment, restaurants, nightclubs & bars. Enjoy staying in this Unesco Heritage town full of history & excitement. Fully equipped kitchen with Washer/Dryer, Queen Sized Bed, pullout Couch, TV, Netflix and 400MbWi-Fi. Our modern beach vibe apartment is perfect for a couple to enjoy and relax. Intagram @pombocartagena

Top guest favorite

A spacious sleeping area features a wooden bed with white bedding set against a textured wall. Soft lighting accentuates the room, while large windows reveal lush greenery outside. Potted plants are placed on either side of the bed, adding a touch of nature to the interior.

Vacation home in La Tigra

4.96 out of 5 average rating, 126 reviews

Green Paradise House The Farm

Relájate en este espacio tranquilo y elegante, en nuestra hermosa vivienda podrás disfrutar de distintas especies de aves, osos perezosos, ranas, visitar los ríos hermosos de la zona de la Tigra de San Carlos y de nuestra finca, y dormir en un lugar lleno de paz, acompañando de todos los sonidos que la naturaleza nos regala. También ten en cuenta que tenemos animales de granja, que tenemos que alimentar Ofrecemos Internet de banda ancha 300 megas sobre 300 5 opciones de menú de restaurantes

Guest favorite

The spacious living room features a comfortable sofa and a stylish coffee table, with large windows showcasing panoramic views of the Cienaga and city skyline. A vibrant floral mural adorns the wall, adding a touch of nature to the modern decor.

Vacation home in CARTAGENA

4.88 out of 5 average rating, 196 reviews

Cartagena Luxurious Resort Condo Radisson

Awesome condo at The Beach Radisson Resort Residences, extraordinary views of the Cienaga, beach and the city; direct hotel beach access to the nicest beaches of Cartagena. 5 minutes to the airport and 10 minutes to the Old city (Wall City) by car . Guest have access to all the Resort amenities like gym, multiple pools, bars, restaurants, spa, sky jacuzzis, wifi, A/C, BBQ areas, 24/7 front desk, security, bellman, room service, etc. Just registered guests are allowed in the apartment

Guest favorite

A cozy living space features a comfortable daybed adorned with decorative pillows in natural tones. A green plant adds a touch of freshness, while wall decor made of organic materials enhances the serene ambiance. Light streams through a window, illuminating the inviting space.

Vacation home in Coco

4.95 out of 5 average rating, 197 reviews

Apart. King bed by casa aire near airport/beaches

Brand new spacious modern apartment by Casa Aire/ 25 minutes from LIR airport/private garden Casa Aire is a small compound, conformed for five accommodations with a unique modern and organic architecture. Creating a relaxed atmosphere ideal for restoring senses after a day of adventure on the bech or nearby national parks. 10 minutes walk from Main steet Coco beach downtown or beach. easy flat wlking areas. FREE ACCESS TO TWO PRIVATE CLUBS at the area. ideal for workations.

Guest favorite

A cozy corner showcases two accent chairs surrounding a small coffee table, with a soft rug underneath. Large windows allow natural light to flood the space, framing a serene view of the distant mountains and the warm hues of sunset.

Vacation home in São Bento do Sapucaí

4.98 out of 5 average rating, 162 reviews

Aconcágua Cottage

Reconnect with nature at SANTALENA REFUGE!! Newly inaugurated, our chalet is thematic and refers to the highest mountain in America, Aconcágua. Like Aconcágua and following the local constructions, this chalet is all solid stone, has a green grass roof and Andean architecture using rustic woods. The most beautiful sunset in the region!! A private and safe location. We are close to Pedra do Baú, Pedra do Baú restaurant and 25 minutes from the city of São Bento.

Guest favorite

A private indoor pool is framed by a minimalistic design, featuring soft lighting and decorative plants. A lounge chair is positioned beside the pool, enhancing the serene atmosphere. The relaxing space is complemented by subtle textures on the walls and a soothing blue hue of the water.

Vacation home in La Fortuna

4.96 out of 5 average rating, 237 reviews

Harmony, Nature & Luxury: Indoor PVT Pool/Jacuzzi

Specially designed to coddle our Airbnb users by providing them luxurious and functional spaces and a touch of immersion in nature that will fill that need for peace and relaxation. Strategically located just 5 minutes away from downtown La Fortuna, this apartment has an indoor private plunge pool/jacuzzi, beautiful views of the Arenal Volcano from its balcony and kitchen, A/C in the room, as well as a bathroom with an open shower with glass roof.

Guest favorite

A modern chalet is depicted with large glass doors opening to a stylish interior. An inviting pool reflects outdoor lighting, while a cozy outdoor seating area is centered near the water. Natural wood and warm tones create a serene ambiance.

Vacation home in Pirenópolis

4.95 out of 5 average rating, 273 reviews

Quinta dos Goyazes - Oka do Pequi Farm

Exclusivity, privacy, quiet in the midst of nature and lots of comfort. Ingredients that make Quinta dos Goyazes Eco Boutique a unique experience in Pirenópolis for those who love to escape the noise, explore nature in an eco boutique full of charm. To make better use of the experience, we recommend a two night minimum. Self-check-in from 3pm and self-checkout UNTIL 11am. In case of delay, a fine of 30% will be charged on the daily rate.

Top guest favorite

A wooden chalet surrounded by lush greenery, featuring large banana plants and diverse tropical foliage. A staircase leads to the entrance, where a porch with chairs offers a view of the natural surroundings.

Vacation home in São Bento do Sapucaí

5 out of 5 average rating, 135 reviews

Treehouse/Emboava Refuge

Located in Serra da Mantiqueira, in a strategic location for sightseeing and 9 km from São Bento Center. Our space has a full kitchen and a deck in the outdoor area. The land is all surrounded by a wire fence. Within the same site, there is a chalet and the main house (where the hosts live), but all independent and distant from each other, maintaining the privacy of each location. We DO NOT provide any meals.

Superhost

A serene infinity pool is visible, reflecting the vibrant sunset over the ocean. Lush greenery surrounds the pool area, and a comfortable seating arrangement is positioned nearby, offering views of the horizon. The sky is adorned with clouds illuminated by warm daylight.

Vacation home in Quepos

4.88 out of 5 average rating, 145 reviews

Villa Calypso

This villa brings you the most spectacular sunset in all of Manuel Antonio. This private and secluded Villa, places you high into the clouds, overlooking the beautifully. Our personal concierge will take the worry out of your stay by planning all your needs. Once you book your reservation, your concierge will reach out to help you start planning the trip of your dreams. * No small kids *

Top guest favorite

A small swimming pool is positioned within a lush garden, surrounded by various tropical plants. Bright blue lounge chairs are situated next to the pool, creating a relaxing spot. Towering palm trees and dense greenery serve as a natural backdrop, enhancing the tranquil atmosphere.

Vacation home in Puerto Viejo de Talamanca

4.99 out of 5 average rating, 229 reviews

Quinta Guarumo #02

Relax on this unique and tranquil getaway in the middle of the Caribbean jungle and just a 5-minute drive from Cocles Beach. We offer a separate bungalow from where you can relax with a breathtaking view of the jungle and its wildlife. They will have the possibility to see toucans, large green limpets, oropendolas, sloths, etc. IMPORTANT: Read Other Aspects to Note.

Top guest favorite

A single-story structure built with stone and adobe features a terracotta roof. Large wooden windows invite natural light, while a swimming pool stretches in the foreground. Scenic mountain views provide a relaxing backdrop, surrounded by garden space and a charming vine.

Vacation home

4.97 out of 5 average rating, 182 reviews

Romantic Apartment for 2

Relajate en este alojamiento único y tranquilo. Nuestros departamentos proveen confort y privacidad, con detalles calidos y terruños. Las vistas impresionantes de los cerros se pueden disfrutar desde la galeria. El espacio comun ofrece una pileta de natacion (habilitada durantes Oct-Abr) y el sol se puede disfrutar debajo de nuestras parras añejas de Torrontes.