Vacation rentals in Semmes

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Semmes

Guests agree: these stays are highly rated for location, cleanliness, and more.

1 of 1 pages1 / 1
Guest favorite
A spacious outdoor pavilion is illuminated by warm string lights along the wooden beams. Several benches are arranged around the perimeter, creating an inviting gathering space. The entrance features a white door framed by a brick wall, offering easy access to the area.
Home in Mobile County
5 out of 5 average rating, 22 reviews

Modern Cottage w/Cabana-15 min to Downtown

Relax in this very comfortable, peaceful, private, pristine, modern cottage while away from home. And please enjoy YouTube Premium on the main TV on us. It’s located close enough to the highway for easy access to beautiful beaches as well as the fun filled exciting Mobile downtown area. It very close to a large number of excellent eatery spots as well as a convenient Publix grocery store and a Super Center Walmart for purchasing all of your favorite items for your stay at the cottage on Kushla.

Guest favorite
The charming exterior of a single-story cottage is framed by a large tree. A welcoming front porch features wooden railings and a green door, while light blue shutters complement the neutral siding. Lush greenery lines the path to the home, enhancing its inviting presence.
Home in Mobile
4.93 out of 5 average rating, 142 reviews

Cozy Home Minutes to Downtown

RELAX & UNWIND at this PEACEFUL, SPACIOUS & COZY Cottage located in the popular Midtown area of Mobile! Upon arrival you will feel right at home. You will find this cottage is very spacious equipped with a King size bed, Queen size bed, Full size bed, Master bathroom & Guest bathroom & a fully equipped kitchen! Enjoy a glass of wine, a good book or some family time outback in the peaceful backyard! A short commute to all the restaurants, bars & attractions! This cottage is the perfect getaway!

Top guest favorite
The charming cottage features a striking red exterior, framed by lush greenery and an expansive oak tree. Soft lighting is strung above the porch, creating an inviting atmosphere. A gravel path leads to the front entrance, enhancing the cottage's cozy appeal.
Cottage in Mobile
5 out of 5 average rating, 145 reviews

Kirkland House in Oakleigh historic district

Quaint and cozy cottage in the heart of the Oakleigh historic district. Minutes from the downtown entertainment district, the new Regions Arena, and the new Mobile International Airport. Within walking distance of restaurants and Mardi Gras parade routes. Enjoy porch sitting in our swing and rockers while enjoying your favorite beverage. The gulf beaches and Dauphin Island are a short drive away. Enjoy fishing and kayaking in the Mobile Delta. Famous Callaghan's Irish Pub is just steps away.

Guest favorite
An entertainment room is shown with a red-felt pool table centered in the foreground. In the background, a modern kitchen with gray cabinets and stainless steel appliances is visible. A 50-inch TV mounted on the wall displays content, while decorative items and a shelf create an inviting ambiance.
Home in Mobile
4.93 out of 5 average rating, 120 reviews

Relax Rejuvenate Refresh near Unv of South Alabama

Come Relax Rejuvenate & Refresh @ this beautiful newly renovated estate designed for Fun, Comfort & Relaxation There are several restaurants, grocery stores & entertainment options in the area Univ of South Al - 0.4 miles Springhill College - 3 miles Mobile Tennis Center - 2 miles Publix - 1 mile Walmart - 1 mile Bel-Air Mall - 4 miles Mobile Airport 4 miles Restaurants 1 to 2 miles away Texas Rd house, Outback, Longhorn’s, Buffalo Wild Wings, Dominoes, Papa Johns, American Deli

Guest favorite
A spacious living area is highlighted by a large L-shaped couch positioned around a stone fireplace. Natural light filters through sheer curtains, illuminating decorative plants that add a touch of greenery. A mounted television offers entertainment options in this inviting space.
Home in Semmes
4.89 out of 5 average rating, 72 reviews

Oak Hill: 2 Acres w/ 4 Bedrooms

Enjoy the "Country" on 2 acres and inside you'll find a freshly remodeled home. The four bedrooms make this a great place for families or friends traveling together. Relax by the pool or smokeless firepit, explore the land, play basketball or board games. Within 5 Minutes: Walmart Supercenter, grocery stores and restaurants. Within 10-15 minutes: Big Creek Lake w/ boat launch & fishing, golf, disc golf, bowling, laser tag, splash pad (seasonal), several parks and shopping.

Guest favorite
A spacious living area features brown leather sofas set on warm wooden flooring. A dining space is visible in the background, with a dark wood table and chairs. Neutral walls are adorned with artwork, and a fireplace serves as a focal point, complemented by a flat-screen TV.
Home in Mobile
4.95 out of 5 average rating, 103 reviews

Convenience Cottage/Close to ALL

Your family will be close to everything when you stay at this centrally-located place. Minutes from South Alabama (USA), Springhill College, Mobile Tennis Center, parks, golf, Mobile Art Museum, Fair Grounds, and much more. The home sits on a large corner lot easy to find. Large privacy fenced back yard for you and your four legged family members to enjoy. Also has a large covered back deck to enjoy along with a gas grill. Walking distance to the park and Japanese’s garden.

Top guest favorite
A spacious living area features light-colored leather seating arranged around a glass coffee table. A ceiling fan and decorative lighting enhance the space. Large windows allow natural light, and a fireplace adds a cozy element, while a mounted television provides entertainment options.
Home in Semmes
4.96 out of 5 average rating, 84 reviews

Spacious 4 bedroom/2 bath in Sweet Home Alabama

Cozy up to the fireplace in this beautiful 4 bedroom/2 bath house in Sweet Alabama. Completely renovated and furnished to sleep up to 8 guests. Oversized master bedroom and bathroom with a big tub to relax in. Complimentary towels, dishes, glasses and coffeemaker with coffee. Centrally located near Historical homes, museums, parks and botanical garden. 10 min. from Mobile airport. 15 min. from Cruise Terminal. *You get 10% off your entire stay if you book for 7 Nights!

Top guest favorite
Tiny home in Semmes
4.93 out of 5 average rating, 71 reviews

Peaceful Backyard Suite

Enjoy the sounds of nature when you stay in this unique place. Shade trees can be seen through the fixed windows near the cathedral ceiling. Feels as though you are in a treehouse! Bedroom has one queen bed & can be closed off from kitchen & living room. House is new and within a fenced yard. It’s to the rear of owner’s home and backs up to a flower nursery. Very quiet. Great place to study, work online, or just relax. Swing on Front Porch. Pets for short term. No cats.

Top guest favorite
Guest suite in Mobile
4.96 out of 5 average rating, 111 reviews

MasterSuite w/ Private Entry and Bathroom

WELCOME to La Carmela. Our Master suite is completely private with your own entry way and own bathroom, access from the patio! You'll be able to come and go as you please without being disturbed. Shared wall with security double doors. The rest of the house will be inaccessible. We are minutes away from I-10 and I-65. Close to downtown to see Mardi Gras, hospitals, universities and cruise terminal. Five minute walk to the laundromat.

Guest favorite
An A-frame cabin is depicted alongside a spacious dock with a covered area. Soft lights are strung around the dock, illuminating the serene water surrounded by trees at sunset. The peaceful landscape reflects a calming atmosphere.
Cabin in Satsuma
4.91 out of 5 average rating, 197 reviews

Secluded cabin on the water jetski, kayak & hottub

Mobile’s number 1 STAYCATION!!! Private waterfront A-frame cabin—your perfect tranquil getaway. Enjoy a huge dock, hot tub, and stunning views in a peaceful, secluded setting. Calm clean waters with jet ski, kayak, boat & hydro bike rentals (seasonal). Cozy 1-bedroom loft, pet-friendly, and great fishing. Just 20 mins from Mobile and 1 hour from beaches & casinos—privacy with convenience! Experience a one of a kind experience

Guest favorite
Cabin in Lucedale
5 out of 5 average rating, 11 reviews

Brushy Creek Cabin

Brushy Creek Cabin is a peaceful, secluded getaway tucked along a quiet creek bank of Brushy Creek and surrounded by nature. Perfect for families, couples, or anyone looking to unplug. The cabin offers a cozy, rustic interior charm with modern comfort. Relax on the covered deck, swim in the cool, clear water, enjoy the sights and sounds of the running rapids, and unwind in a calm, wooded setting—your perfect creekside escape.

Top guest favorite
A serene outdoor area features a hot tub, fire pit, and a sandy beach leading to an expansive body of water. A long pier extends into the bay, framed by lush greenery and white gravel paths, creating a tranquil setting for relaxation.
Townhouse in Coden
4.94 out of 5 average rating, 600 reviews

*Bay View* Near Dauphin Island HOT TUB! Unit B

Welcome to the bay! The best of both worlds. Close to dauphin island and close to downtown Mobile! This is a home with two separate units on the property. Unit B (this unit) is the downstairs unit. You have 3 private doors for you to come in and out. Your own outdoor space includes: hot tub, grill and outside area. -500 Ft Pier, Boat House and fire pit are a shared space. - We are always available for questions!

Popular amenities for Semmes vacation rentals

  1. Airbnb
  2. United States
  3. Alabama
  4. Mobile County
  5. Semmes