Vacation rentals in Semmes

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Top-rated vacation rentals in Semmes

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite
A modern bedroom features a spacious bed with neutral bedding and decorative pillows, complemented by a geometric area rug on light wooden floors. Two large windows with sheer curtains allow natural light to fill the space, while a stylish television stands on an angular wooden stand.
Townhouse in Washington Square
4.96 out of 5 average rating, 204 reviews

Downtown , Modern Spacious & Near I-10

Enjoy a little piece of Mobile, Alabama by staying at this centrally located townhouse near all the best restaurants and the hustle and bustle of downtown. This unique space is a minute from I-10 giving you easy access to the interstate and quick driving time to just about anywhere. Minutes from the convention center, cruise terminal, Washington Square, and the famous Callaghan's Irish Social Club. Spacious, clean, modern, and convenient are all descriptions for this cute, newly remodeled space.

Guest favorite
A spacious outdoor pavilion is illuminated by warm string lights along the wooden beams. Several benches are arranged around the perimeter, creating an inviting gathering space. The entrance features a white door framed by a brick wall, offering easy access to the area.
Home in Mobile County
5 out of 5 average rating, 15 reviews

Modern Cottage w/Cabana-15 min to Downtown

Relax in this very comfortable, peaceful, private, pristine, modern cottage while away from home. And please enjoy YouTube Premium on the main TV on us. It’s located close enough to the highway for easy access to beautiful beaches as well as the fun filled exciting Mobile downtown area. It very close to a large number of excellent eatery spots as well as a convenient Publix grocery store and a Super Center Walmart for purchasing all of your favorite items for your stay at the cottage on Kushla.

Top guest favorite
A cozy detached guest house is presented, featuring a dark brown door and two windows adorned with white curtains. The exterior is painted in neutral tones, complemented by a small table and two blue chairs placed outside. An American flag is displayed on the front, and a wooden fence provides privacy.
Guesthouse in Spanish Fort
4.98 out of 5 average rating, 153 reviews

Adorable 1-Bedroom Guesthouse in Spanish Fort

Enjoy a private space to call home during your Spanish Fort stay, cozy detached guest house with full bath, kitchenette, dinning space and closet space with private entrance. Amazing location only 10 minutes away from Mobile Bay and five rivers delta with the best fishing in the area. US-98 Causeway offers some of the most popular Cafe/Bars and amazing seafood, Italian and Mexican dinning on the Bay. Also within 5 minutes of shopping centers, 20 minutes from Fairhope and 45 to Pensacola Beach.

Guest favorite
A stylish living area features a sleek black sofa paired with two soft, pastel stools on a textured area rug. Artistic black-and-white wall art adorns the walls, and a full-length mirror reflects the space, complemented by warm lighting from wall sconces.
Home in Mobile
4.98 out of 5 average rating, 129 reviews

Peach & Pine Cottage - Pet friendly in Midtown

Peach & Pine Cottage, named for its color palette and featured tree, is our third listing! In this home, we embraced the retro energy with pops of mid-century modern throughout and paid homage to the fab fifties in almost every room. You’ll feel both comfortable and relaxed in a space filled with mixed metals, pastel colors, & plenty of lighting. As always, we want you & your pets to feel at home. Checkout our other properties, Magnolia Belle & the Oak Haven, to see the experience we provide!

Guest favorite
Tiny home in Semmes
4.89 out of 5 average rating, 36 reviews

Peaceful Backyard Suite

Ideal for longer term stays. Enjoy the sounds of nature when you stay in this unique place. Shade trees can be seen through the fixed windows near the cathedral ceiling. Feels as though you are in a treehouse! 1 queen bed or couch for sleep. (Linens available). House is new and within a fenced yard. It’s to the rear of owner’s home and backs up to a flower nursery. Very quiet. Great place to study, work online, or just relax. Porch on front with swing. Ask about pets for short term. No cats.

Top guest favorite
The exterior of a modern brick home is showcased, featuring a sloped roof and large front windows. Well-maintained landscaping includes shrubbery and a neat lawn, with a paved walkway leading to the entrance. The inviting facade is highlighted under a clear blue sky.
Home in Semmes
4.97 out of 5 average rating, 36 reviews

The Bare Minimum Bachelor Pad 3 bed/2 baths

If you're looking for simplicity and comfort without the frills, you've found the perfect spot! Located in Semmes, Al near mobile. This 3-bedroom, 2-bath retreat is all about the basics, offering just what you need for a laid-back stay. No fuss, no clutter, just space to relax, recharge, and enjoy the essentials. With no distracting art on the walls or extra knick-knacks, this place is perfect for anyone who appreciates clean lines and an "everything-you-need-and-nothing-you-don't" vibe. 😊

Superhost
Apartment in Mobile
4.83 out of 5 average rating, 23 reviews

The Den, Comfortable loft midtown

Come stay at the Den! A renovated yet vintage loft in Midtown Mobile. This property is located less than a five minute drive to Downtown Mobile. Close to Starbucks, and the new Aldi's and more. This apartment has been completely renovated with granite and features refinished, original hardwood floors. This is a large studio apartment that has a living space, queen size bed, and kitchenette. The kitchen has a coffee and tea bar, two burner range, microwave, dishwasher and toaster oven.

Guest favorite
A cozy corner of the living area features a hanging rattan chair adorned with orange cushions. A wooden coffee table with two glasses and a bottle of wine is positioned in front, while a black metal shelving unit with potted plants adds greenery to the space.
Home in Mobile
4.89 out of 5 average rating, 441 reviews

Historic Midtown • Walkable • 5 Min to DT • WiFi

Centrally located in charming, walkable Midtown Mobile’s Old Dauphin Way Historic District, my home is just minutes from: 🎭 Mardi Gras parade route (2 mi), USS Alabama (5.3 mi), GulfQuest Museum (2.8 mi), Saenger Theatre (2.6 mi), LODA District (2.6 mi), Ladd-Peebles Stadium (0.8 mi), and Convention & Civic Centers (2.9 mi). 🏥 Near USA Health (2.5 mi) & Mobile Infirmary (3.2 mi). 🏖️ Dauphin Island (45 mins). ✈️ 15 mins to Mobile Regional Airport with quick access to I‑10/I‑65.

Guest favorite
A serene bedroom is equipped with a queen-size bed featuring dark wood furniture. The walls are painted in soft light tones, and natural light filters through the blinds of two windows. A ceiling fan provides ventilation, while a chair with decorative cushions adds a cozy touch.
Home in Mobile
4.93 out of 5 average rating, 105 reviews

Three Notch Cutie

Your family will be close to everything at this centrally located home located in the Tillman's corner area of Mobile, AL. The house is approximately 1/4 mile from a new Dollar General and 3 miles from interstate I-10. In 2024 we did an interior renovation of the house, so that it now features LED lighting, freshly painted walls, new floors, new appliances, a tile shower, granite countertops, and brand new furniture. We ask that you take care of our investment. Thank you!

Guest favorite
A single-story home is set on a large lot surrounded by trees. The front features a welcoming porch with steps leading to the entrance, framed by symmetrical windows with dark shutters. The yard is covered in grass, providing ample outdoor space.
Home in Mobile
4.93 out of 5 average rating, 59 reviews

Cozy South Alabama Home

Your family will be close to everything when you stay at this centrally-located place. Minutes from South Alabama (USA), Springhill College, Mobile Tennis Center, parks, golf, Mobile Art Museum, Fair Grounds, and much more. The home sits on a large lot easy to find. Large fenced back yard for you and your four legged family members to enjoy. Also has a large covered back deck to enjoy along with a gas grill. Walking distance to the park and Japanese’s garden.

Top guest favorite
The living room features two comfortable armchairs and a plush sofa, arranged around a glass-top coffee table. Natural light enters through large windows adorned with bamboo shades. A decorative area rug adds texture to the hardwood floor, while the wall displays the name 'BAY'.
Cottage in Mobile
4.96 out of 5 average rating, 242 reviews

{B A Y} Quiet Midtown Retreat with King Bed

Please take a few minutes to read our reviews and hear why guests love our place so much... we work hard to provide a five star experience for every guest we host. We know you will love it too! *We offer weekly and monthly discounts* Our duplex is situated in a very friendly, walkable neighborhood. Starbucks is just a short stroll down the street. Walking distance to Aldi, Guncles gluten free bakery, and Soul Caffeine coffee shop.

Top guest favorite
The exterior of a two-story home is shown, featuring a well-manicured lawn and a welcoming porch with seating. Red, white, and blue decorations hang along the porch, and an American flag is displayed prominently. Lush greenery surrounds the property, enhancing the inviting atmosphere.
Guest suite in Mobile
4.96 out of 5 average rating, 160 reviews

Haven on Hamilton

Cozy, private guest suite convenient to the interstate, airport and great local restaurants. Located just half an hour from Dauphin Island and historical downtown Mobile. Local attractions include the USS Alabama, Mobile cruise terminal, and more. You can have the quiet, country feel with all the convenience of city living.

Popular amenities for Semmes vacation rentals

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