
House vacation rentals in Santo Domingo Este
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Top-rated house rentals in Santo Domingo Este
Guests agree: these houses are highly rated for location, cleanliness, and more.

High-Class Home + Pool, Backyard, Security & More!
We offer the best space with the best amenities to spend time with family and friends from DR. Come and check: • Hot water🛁 • Visitors are allowed🫂 • Air Conditioning in all areas❄️ • Only minutes away from Avenida España, SDQ airport, beaches, retail stores, banks, malls, restaurants, and clubs ✈️🏖️🛍️🏧🍸 • Private pool with spacious backyard, patio furnitures and BBQ 🏊♀️🥩 • Perfect for families, couples, or groups of friends 👣 • 5G internet 🛜 • Fully equipped entertainment room 🍿🎲

Casa Serena: cozy, modern, spacious and peaceful
Welcome to Casa Serena! A cozy, modern, and spacious house that exudes tranquility... perfect for trips with family or friends seeking a peaceful retreat. The ideal home for those looking to stay in a central area of Santo Domingo while also enjoying the benefits of a low-density residential neighborhood. With easy access, minimal traffic, high safety standards, serene surroundings, friendly neighbors, and a sense of peace, Casa Serena in the La Castellana urbanization is the perfect choice.

Colorful Caribbean house in the Zona Colonial
Enjoy a marvelous stay at this gorgeous, colorful and spacious home at the Zona Colonial. Light, airy rooms and amazing private outdoors create a unique caribbean flair. Relax in the tropical garden...refresh yourself with a dip into the tiny pool…dine under the stars or enjoy the amazing view of the San Francisco monastery ruins from the balcony. The famous Plaza de España is a few steps away and all the historical sites, museums, restaurants, cafés and bars are within easy walking distance.

casa bella 3 camas 1 king + 2 twin airport 15min.
Relájate en este espacio tranquilo,elegante y seguro aeropuerto (15 minutos) playas ,calles principales Supermercados cerca (zona súper tranquila segura y muy confortable ) 1–incluimos servicio de lavado y secado 2–wifi 3–Tv Smart 55 sala y 65 hab principal 4–puerta principal inteligente con clave 5–muebles en leather 6– cama principal king size 7–aire acondicionado en la principal 8–parqueo techado y cerrado 9–inversor de Luz 24 horas incluido Soy súper atento con mis huéspedes

Casa Escondidas is close to everything you need.
Casa completa con piscina, perfecta para compartir en familia en un ambiente seguro y tranquilo de Santo Domingo Este. Ubicación ideal para explorar lo mejor de la zona: a minutos de Playa Juan Dolio, Boca Chica, el histórico Parque Colón, el impresionante Parque Nacional Los Tres Ojos y el Acuario Nacional. Con supermercados, restaurantes y la Avenida España muy cerca, tendrás todo lo que necesitas para combinar descanso, diversión y aventura en un solo lugar.

Stunning villa in Zona Colonial
Casa Republic – Historic Charm, Modern Luxury Tucked away in Santo Domingo’s iconic Zona Colonial, Casa Republic is a 4-suite architectural gem where colonial heritage meets contemporary design. Cool off in your private pool, unwind on the rooftop terrace, or relax in elegant indoor-outdoor spaces crafted for comfort and style. With room for up to 8 guests, this one-of-a-kind home offers a refined retreat in the charm of the old city.

Cozy, central and well-equipped place
We are located in a central and quiet part of the city, with access to 27 de Febrero, Máximo Gómez, and Jhon F. Kennedy avenues. Nearby are the Ibero-American University (Uníbe), Zambil shopping center, Banco Popular Dominicano Tower, as well as pharmacies and health centers. The apartment is located on the first floor, with independent access, parking, and an electric gate. It has a cable system, high-speed WiFi, and an inverter.

Cozy little house in the heart of the Colonial Zone
A cozy 2-bedroom house for 4 people, located in the heart of the Colonial Zone in Santo Domingo, within walking distance of all cultural and tourist attractions. It has 2 comfortable bedrooms and a study with a sofa bed; 2 bathrooms, a nice living room, large dining room, equipped kitchen and a beautiful inner courtyard. Wonderful for vacations and cultural trips, ideal for couples, families, friends, and business travelers.

La Casita de Gazcue Bright Suite C
This simple but charming accommodation offers you a relaxing experience in a privileged location: just 12 minutes walk from the historic Colonial Zone and three blocks from the iconic Malecón, where you can enjoy sea views, restaurants, and nightlife. Ideal for relaxing without going far, our space combines serenity with quick access to the main tourist, cultural and gastronomic spots. Your comfort is our priority.

Charming Old City Corner House
This charming 2 bedroom corner house is located in the walled colonial city of Santo Domingo. It’s only a few steps away from historical attractions, museums, restaurants, coffee shops, bars, souvenir shops, bakeries, supermarket and lovely squares. The beautiful covered terrace, overlooking the rooftops of the old town with living area, hammock and BBQ is perfect for a relaxing afternoon or evening.

Your 2BR House + Terrace in the Colonial Zone
Feel the history in this authentic Colonial house from the XVI century with all the modern amenities you will need to make your trip unforgettable. Enjoy a walk to history in the oldest city of America. Visit impressive cultural sites, exquisite restaurants and bars. Have fun in a great night atmosphere. In just minutes you can be in the ocean shore ( malecon ) or in the Colonial promenade.

Heart of the colonial zone, Billini 54
At the very heart of the most exclusive part of the colonial city where all the fun and interesting activities take place. This beautiful one-bedroom apartment is on the first floor of a small building next to the colonial gate 4D cinema, electric bike rentals, beer market, food markets, historical landmarks, exclusive boutiques, galleries, restaurants and bars.
Popular amenities for Santo Domingo Este house rentals
House rentals with a pool

Villa in Santo Domingo East with pool, gazebo, BBQ!

Intimate and luxury Villa with private pool

Villa oasis

Private home with pool, AC, Wi-Fi, BBQ, Santo Dom.

Royal Villa with a swimming pool in Villa Mella SD Norte.

Charming 2BDR Suite! - SPECIAL PROMOTION

Atypical beachy vibes house, ciudad colonial

Villa Marayath!To enjoy with all families & friend
Weekly house rentals

Luxury Morden house with Jacuzzi Zona Colonial.!

Sweet home, 3 A/C, 3 Parking spaces. Av. Jacobo Mujluta

House near the airport, queen bed + sofa bed.

Charming Colonial House!

Cozy & Beautiful City Center House with Jacuzzi

Shulywow Santo Domingo West Luxury Comfort Safe

COZY 3-BED HOUSE FIRST Floor KING Bed

House with an excellent location
Private house rentals

Luxury, Classy Private House In Santo Domingo

Jacuzzi, the perfect house for you and yours

Casa Stella in Santo Domingo Norte

Casa Linda. Spacious family house in the best area.

My refuge near the airport

House in Santo Domingo

Amazing house with pool in Santo Domingo

Casa RossAmor
When is the best time to visit Santo Domingo Este?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | € 47 | € 46 | € 46 | € 50 | € 47 | € 50 | € 47 | € 48 | € 52 | € 43 | € 46 | € 47 |
| Avg. temp | 26°C | 26°C | 26°C | 27°C | 27°C | 28°C | 28°C | 28°C | 28°C | 28°C | 27°C | 26°C |
Quick stats about house rentals in Santo Domingo Este

Total vacation rentals
Explore 590 vacation rentals in Santo Domingo Este

Nightly prices starting at
Santo Domingo Este vacation rentals start at € 9 per night before taxes and fees

Verified guest reviews
Over 9,550 verified reviews to help you choose

Family-friendly vacation rentals
330 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 180 rentals that welcome pets

Vacation rentals with a pool
130 properties feature pools

Rentals with dedicated workspaces
200 properties have a dedicated workspace

Wi-Fi availability
550 of Santo Domingo Este vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Santo Domingo Este rentals

4.6 Average rating
Santo Domingo Este stays receive an average rating of 4.6 out of 5 from guests
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