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House vacation rentals in Santo Domingo De Guzmán

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Top-rated house rentals in Santo Domingo De Guzmán

Guests agree: these houses are highly rated for location, cleanliness, and more.

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Superhost
Home in Los Frailes
4.81 out of 5 average rating, 32 reviews

High-Class Home + Pool, Backyard, Security & More!

We offer the best space with the best amenities to spend time with family and friends from DR. Come and check: • Hot water🛁 • Visitors are allowed🫂 • Air Conditioning in all areas❄️ • Only minutes away from Avenida España, SDQ airport, beaches, retail stores, banks, malls, restaurants, and clubs ✈️🏖️🛍️🏧🍸 • Private pool with spacious backyard, patio furnitures and BBQ 🏊‍♀️🥩 • Perfect for families, couples, or groups of friends 👣 • 5G internet 🛜 • Fully equipped entertainment room 🍿🎲

Top guest favorite
A spacious living area features a light-colored sofa adorned with decorative pillows. A coffee table with floral arrangements complements two blue accent chairs nearby. Large windows allow natural light to fill the room, enhancing the bright, airy atmosphere.
Home in Los Prados
4.99 out of 5 average rating, 129 reviews

Casa Serena: cozy, modern, spacious and peaceful

Welcome to Casa Serena! A cozy, modern, and spacious house that exudes tranquility... perfect for trips with family or friends seeking a peaceful retreat. The ideal home for those looking to stay in a central area of Santo Domingo while also enjoying the benefits of a low-density residential neighborhood. With easy access, minimal traffic, high safety standards, serene surroundings, friendly neighbors, and a sense of peace, Casa Serena in the La Castellana urbanization is the perfect choice.

Guest favorite
A modern living area is presented with white leather seating and a glass coffee table. Accent lights illuminate built-in shelving displaying decorative items. A fan and a television are positioned within the space, while dark curtains frame large windows.
Home in Los Frailes
4.89 out of 5 average rating, 235 reviews

casa bella 3 camas 1 king + 2 twin airport 15min.

Relájate en este espacio tranquilo,elegante y seguro aeropuerto (15 minutos) playas ,calles principales Supermercados cerca (zona súper tranquila segura y muy confortable ) 1–incluimos servicio de lavado y secado 2–wifi 3–Tv Smart 55 sala y 65 hab principal 4–puerta principal inteligente con clave 5–muebles en leather 6– cama principal king size 7–aire acondicionado en la principal 8–parqueo techado y cerrado 9–inversor de Luz 24 horas incluido Soy súper atento con mis huéspedes

Guest favorite
A serene outdoor area features a private swimming pool bordered by stone walls. Potted plants are placed strategically around the pool, enhancing the tranquil atmosphere. A shaded seating area is visible under a blue canopy, providing a space for relaxation.
Home in Santo Domingo Este
4.73 out of 5 average rating, 150 reviews

Casa Escondidas is close to everything you need.

Casa completa con piscina, perfecta para compartir en familia en un ambiente seguro y tranquilo de Santo Domingo Este. Ubicación ideal para explorar lo mejor de la zona: a minutos de Playa Juan Dolio, Boca Chica, el histórico Parque Colón, el impresionante Parque Nacional Los Tres Ojos y el Acuario Nacional. Con supermercados, restaurantes y la Avenida España muy cerca, tendrás todo lo que necesitas para combinar descanso, diversión y aventura en un solo lugar.

Top guest favorite
A bright and airy entrance leads to a serene outdoor area with a pool. The space is framed by modern glass walls, showcasing inviting seating and greenery. Natural light filters through, enhancing the layout that connects indoor and outdoor living.
Home in Ciudad Colonial
5 out of 5 average rating, 28 reviews

Stunning villa in Zona Colonial

Casa Republic – Historic Charm, Modern Luxury Tucked away in Santo Domingo’s iconic Zona Colonial, Casa Republic is a 4-suite architectural gem where colonial heritage meets contemporary design. Cool off in your private pool, unwind on the rooftop terrace, or relax in elegant indoor-outdoor spaces crafted for comfort and style. With room for up to 8 guests, this one-of-a-kind home offers a refined retreat in the charm of the old city.

Top guest favorite
The living area features a light blue sofa paired with a small neutral-toned coffee table. A colorful piece of wall art hangs above the sofa, and a dining table is visible in the corner. A ceiling fan and green curtains enhance the space, while natural light enters from a nearby window.
Home in Santo Domingo
4.95 out of 5 average rating, 155 reviews

Cozy, central and well-equipped place

We are located in a central and quiet part of the city, with access to 27 de Febrero, Máximo Gómez, and Jhon F. Kennedy avenues. Nearby are the Ibero-American University (Uníbe), Zambil shopping center, Banco Popular Dominicano Tower, as well as pharmacies and health centers. The apartment is located on the first floor, with independent access, parking, and an electric gate. It has a cable system, high-speed WiFi, and an inverter.

Guest favorite
A welcoming sitting area features a comfortable gray sofa paired with two wicker chairs and a glass coffee table. Lush green plants are placed around the space, enhancing the ambiance. Colorful tiles cover the floor, contributing to a cozy atmosphere.
Home in Ciudad Colonial
4.96 out of 5 average rating, 214 reviews

Cozy little house in the heart of the Colonial Zone

A cozy 2-bedroom house for 4 people, located in the heart of the Colonial Zone in Santo Domingo, within walking distance of all cultural and tourist attractions. It has 2 comfortable bedrooms and a study with a sofa bed; 2 bathrooms, a nice living room, large dining room, equipped kitchen and a beautiful inner courtyard. Wonderful for vacations and cultural trips, ideal for couples, families, friends, and business travelers.

Guest favorite
Home in Gazcue
4.83 out of 5 average rating, 168 reviews

La Casita de Gazcue Bright Suite C

This simple but charming accommodation offers you a relaxing experience in a privileged location: just 12 minutes walk from the historic Colonial Zone and three blocks from the iconic Malecón, where you can enjoy sea views, restaurants, and nightlife. Ideal for relaxing without going far, our space combines serenity with quick access to the main tourist, cultural and gastronomic spots. Your comfort is our priority.

Top guest favorite
A covered terrace features a wooden floor, surrounded by potted plants. Four chairs with colorful cushions face a wooden table. A hammock and a cozy blue chair are positioned nearby, with an open view of the rooftops in the background.
Home in Ciudad Colonial
4.95 out of 5 average rating, 110 reviews

Charming Old City Corner House

This charming 2 bedroom corner house is located in the walled colonial city of Santo Domingo. It’s only a few steps away from historical attractions, museums, restaurants, coffee shops, bars, souvenir shops, bakeries, supermarket and lovely squares. The beautiful covered terrace, overlooking the rooftops of the old town with living area, hammock and BBQ is perfect for a relaxing afternoon or evening.

Guest favorite
An inviting entrance features a pair of wooden doors, framed by a rustic archway and accented by a central chandelier. Warm terracotta tiles reflect natural light, guiding visitors toward the inner living spaces, while artwork enhances the walls along the corridor.
Home in Ciudad Colonial
4.87 out of 5 average rating, 102 reviews

Your 2BR House + Terrace in the Colonial Zone

Feel the history in this authentic Colonial house from the XVI century with all the modern amenities you will need to make your trip unforgettable. Enjoy a walk to history in the oldest city of America. Visit impressive cultural sites, exquisite restaurants and bars. Have fun in a great night atmosphere. In just minutes you can be in the ocean shore ( malecon ) or in the Colonial promenade.

Superhost
An outdoor area features a colorful mural and a spacious sitting arrangement with wooden and green elements. Unique design elements include a circular seating area and a barbecue grill nearby. Lush greenery complements the tiled floor, creating a harmonious blend of nature and comfort.
Home in Ciudad Colonial
4.81 out of 5 average rating, 32 reviews

House with Jacuzzi in Zona Colonial

Immerse yourself in the charm of the Colonial Zone with a stay at this exclusive home that combines history, comfort and luxury. Located in the heart of Santo Domingo, this space offers a unique experience with its elegant colonial design and all the modern amenities. Ideal for couples, travelers looking for tranquility or those who want to experience the magic of the city in style.

Guest favorite
A two-story building is depicted, featuring a light-colored exterior and a pop of blue accents. The lower level includes a planter box and secured entrances. A person rides a bicycle nearby, adding a sense of activity to the quiet street setting adorned with plants.
Home in Ciudad Colonial
4.87 out of 5 average rating, 317 reviews

Heart of the colonial zone, Billini 54

At the very heart of the most exclusive part of the colonial city where all the fun and interesting activities take place. This beautiful one-bedroom apartment is on the first floor of a small building next to the colonial gate 4D cinema, electric bike rentals, beer market, food markets, historical landmarks, exclusive boutiques, galleries, restaurants and bars.

Popular amenities for Santo Domingo De Guzmán house rentals

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Quick stats about house rentals in Santo Domingo De Guzmán

  • Total vacation rentals

    Explore 500 vacation rentals in Santo Domingo De Guzmán

  • Nightly prices starting at

    Santo Domingo De Guzmán vacation rentals start at € 9 per night before taxes and fees

  • Verified guest reviews

    Over 12,010 verified reviews to help you choose

  • Family-friendly vacation rentals

    210 properties offer extra space & kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 130 rentals that welcome pets

  • Vacation rentals with a pool

    100 properties feature pools

  • Rentals with dedicated workspaces

    190 properties have a dedicated workspace

  • Wi-Fi availability

    460 of Santo Domingo De Guzmán vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Santo Domingo De Guzmán rentals

  • 4.6 Average rating

    Santo Domingo De Guzmán stays receive an average rating of 4.6 out of 5 from guests

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