
Vacation rentals in Patuxent
Find and book unique accommodations on Airbnb
Top-rated vacation rentals in Patuxent
Guests agree: these stays are highly rated for location, cleanliness, and more.

Waterfront. Spacious. HotTub. Kayaks. DogFriendly.
Custom waterfront home with everything you need to relax and recharge. Two levels of decks offer amazing views of the changing tides on Cat Creek. Soak in the hot tub and watch the eagles soar by, or head down to the dock for crabbing, fishing, and kayaking during high tide. Located in historic Southern Maryland, this quiet, hidden estuary makes for a unique getaway with great amenities. Fast WiFi for work, game room for fun, and a fenced-in yard for dogs. 1 hour from DC but feels worlds away.
5.0 out of 5 average rating, 107 reviews
*Brand New | Modern | Lux 4 BR | Huge | 24 m to DC
Dee's Lounge will offer you the ULTIMATE perfect stay! Indulge in a luxurious and refined experience that is sure to leave you feeling refreshed, relaxed, and rejuvenated! This space is designed to make you feel like you've escaped your everyday life. Whether it's a girl trip, family time or hanging with your friends, you are sure to have an amazing time! We are readily available to accommodate your needs and make sure that you enjoy your time here! UPDATE 7/17 Grass room is under construction
4.91 out of 5 average rating, 158 reviews
Hideaway on the Bay: Waterfront Vintage A Frame
The Hideaway on the Bay is a waterfront A frame where you can disconnect from the things that can wait so you can connect with the people who matter most. A place where kids fall in love with nature, and where old friends make new memories. The house is a 2 bed 1 bath 1974 flat top A Frame that sits on two acres on the outskirts of Lusby, MD—and a low traffic hour(ish) drive from the DMV. Enjoy the indoor fireplace, outdoor fire pit, swinging chairs, kayaks, canoe, fish, and catch crabs --
4.91 out of 5 average rating, 269 reviews
The River House, a Wicomico Beach Retreat
Located right on the water of the Wicomico River with a private sandy beach, The River House will become your favorite retreat! This 5 bdrm, 3 bath fully stocked home has all the convenience of modern construction (including wifi) but maintains the vintage charm of the original property. The acre+ plot is very private with spectacular forest & water views. Fun can be found in every direction and for all ages! It has two bottom floor bed/bath combos, plus a fabulous sleeping loft for the kids!
4.91 out of 5 average rating, 129 reviews
Beautiful Rural Suite near Washington, D.C.
Enjoy a rural environment only 50 minutes outside of Washington, D.C., and 45 minutes away from Andrew's Air Force Base. Located in a quiet wooded neighborhood with horses, goats, ducks, and more this property allows children space to run and play. Stores are less than 10 minutes down the road. This is a perfect little haven, fully equipped with a kitchen and laundry facilities. Parking is available for boats and trailers. Please Note: Sunday check-in is at 4pm, unless requested otherwise.
4.9 out of 5 average rating, 314 reviews
Eagles Nest: Studio Apartment, Maryland
Serenity! Studio apartment—peaceful, natural scenery near Washington D.C., 2 hospitals, 2 wineries, multiple restaurants, horse-back riding, biking trails, fishing, Dr. Mudd’s historic house, All American Harley Davisson, Budds Creek, Maryland International Raceway, & 4 Military Bases:. During downtime, relax with 2 TVs, Wi-fi, a mini kitchen (Keurig, fridge, microwave, & cabinets with dishes for 4 people). Enjoy the private washer/dryer, full bath, dining table, work desk & walk-in closet.
4.98 out of 5 average rating, 84 reviews
Blue Pearl-Luxury estate with private dock/jacuzzi
The Blue Pearl is a luxurious river front estate with a private pier to catch crabs, fish and kayak. Soak in the outdoor jacuzzi and enjoy the river life. Three bedrooms with three full bath en-suites and over 2800 square feet of luxury accommodations await you. Office has Queen sleeper sofa. Pull up to your private boat dock, catch blue crabs with the provided traps, toast s’mores in the firepit while sitting in your Adirondack chairs. Enjoy two decks to view the sunrises and sunsets.
4.97 out of 5 average rating, 107 reviews
Luxury Farmette -Private & Secluded-1hr to DC
Plan your tranquil getaway to the countryside and escape to a luxury dream farmhouse. Located on 5 acres, the renovated home offers peace in a quiet, private location. Guests have access to a pool and outdoor shower, fire pit, a covered grilling area and a playground for children. The home is located approximately 1hr from Washington DC and is the perfect place for a retreat, family vacation and everything in between! Plenty of parking available for those traveling with boat/camper/RV.
4.99 out of 5 average rating, 129 reviews
The Southern Maryland (SoMD) Diamond House
A covered front porch with porch swing and multi tier decking in rear over looks a beautiful gunite pool with a slide and a diving board. Depth 3 1/2 ft to 13 foot. Nice big country kitchen. The sliding glass doors from kitchen go to deck over looking pool, nice landscaping, and forest. The master bedroom with a master bath, sliding glass door to deck over looking pool. Full basement patio and pool deck. Has full size bar, full brick hearth fireplace and a full bath. Pool table & Bar.
4.81 out of 5 average rating, 21 reviews
Private Pool | Modern | Lux 4 BR Retreat | Near DC
Relax with the whole family at this peaceful estate. Newly Remodeled Modern Farmhouse. Enjoy a stylish master bedroom with a double shower and deep freestanding soaker tub. Plenty of areas to relax in and watch movies or enjoy the beauty of the 100-foot-tall trees on the spacious 2-acre lot. Have fun with the Queen-sized bunk beds or if you have a little work to do you can use the home office complete with docking station, web cam and double large screen monitors.
4.84 out of 5 average rating, 123 reviews
Quiet cottage in the woods. King-bed suite.
Take it easy at this unique and tranquil getaway. Open floor plan with all the modern conveniences. King size bed, with space for an additional queen size air mattress. Washer, dryer, shower/bathtub. Note, there is no smoking or vaping allowed inside the Cottage, and absolutely no "4/20" products allowed on the property. Two night minimum for all reservations, and due to documented medical allergy concerns we are unable to host pets/animals of any kind.
5.0 out of 5 average rating, 64 reviews
Cottage on the Creek
The Cottage is perfectly perched alongside Cuckold Creek showcasing the beauty of Southern Maryland. Our home provides plenty of space for relaxing together with a water view everywhere you turn. Each space is set up to provide you with the comforts of home, so you can relax and enjoy being in the moment. Located in the heart of Hollywood, not too far from stores or restaurants, but still "away from it all". ✨
4.99 out of 5 average rating, 110 reviewsPopular amenities for Patuxent vacation rentals
Other great vacation rentals in Patuxent

5 acre oasis near Budd's Creek, MIR & DC region.
4.81 out of 5 average rating, 16 reviews
Grand Tudor Home w/ Saltwater Pool & Hot Tub
5.0 out of 5 average rating, 8 reviews
Chesapeake Escape Southern Md, Bay Adventures!
4.95 out of 5 average rating, 58 reviews
Spacious 4BR Near DC | Free Parking | Sleeps 11
5.0 out of 5 average rating, 14 reviews
Cozy 5-Bed Retreat, Heated Spa
4.78 out of 5 average rating, 60 reviews
Luxury Farm Stay
5.0 out of 5 average rating, 5 reviews
*NEW* Huge 5Br Entertainment Retreat, Near DC
4.92 out of 5 average rating, 61 reviews
Huge Farmstay w/ Pool, Animals, Pond, & Game Room
4.9 out of 5 average rating, 61 reviewsDestinations to explore
- New York City Vacation rentals
- Philadelphia Vacation rentals
- Washington Vacation rentals
- Ocean City Vacation rentals
- Pittsburgh Vacation rentals
- Raleigh Vacation rentals
- Virginia Beach Vacation rentals
- Jersey City Vacation rentals
- Newark Vacation rentals
- Baltimore Vacation rentals
- Richmond Vacation rentals
- Atlantic City Vacation rentals
- National Mall
- The White House
- Walter E Washington Convention Center
- Nationals Park
- FedExField
- Capital One Arena
- Georgetown Waterfront Park
- Howard University
- Arlington National Cemetery
- Washington Monument
- National Harbor
- National Museum of African American History and Culture
- Smithsonian National Zoological Park
- Museum of the Bible
- Smithsonian National Air and Space Museum
- Smithsonian American Art Museum
- Catholic University Of America
- The Pentagon
- Great Falls Park
- George Mason University
- Arundel Mills
- Lincoln Park
- Breezy Point Beach & Campground
- United States Naval Academy





