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House vacation rentals in Mytilini

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Top-rated house rentals in Mytilini

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Guest favorite
The living area features a modern corner sofa, a glass coffee table, and stone accent walls. A spiral staircase leads to the upper levels, while the open kitchen is visible in the background, showcasing stainless steel appliances and a bright, functional layout.
Home
4.86 out of 5 average rating, 14 reviews

Cozy Mytilene Downtown

Ζήστε την αυθεντική Μυτιλήνη από την καρδιά της πόλης! Καλώς ήρθατε στο παραδοσιακό μας σπίτι, πλήρως ανακαινισμένο με μοντέρνες πινελιές, που βρίσκεται μέσα στην ιστορική αγορά της Μυτιλήνης, λίγα μόλις βήματα από το λιμάνι, τα καφέ, τις ταβέρνες και τα μουσεία. Το διαμέρισμα συνδυάζει την αυθεντικότητα της Λεσβιακής αρχιτεκτονικής με την άνεση του σύγχρονου design. Είστε μέσα στην αγορά με τα παραδοσιακά σοκάκια που θα βρείτε όλα τα μαγαζιά σε ένα δρόμο καθώς και το λιμάνι στα 4-5 λεπτά!

Top guest favorite
The open-plan living area features a well-equipped kitchen with modern appliances and a sleek countertop. A comfortable gray sofa sits adjacent to a wooden coffee table, while a small dining table is visible nearby. Large curtains frame the windows, allowing natural light to fill the space.
Home
4.97 out of 5 average rating, 31 reviews

Beautiful home for holidays.

Relax in this calm and stylish space. The house is located in a calm area very close to the center of Mytilene. It has air conditioning TV all electrical devices. Fast internet and all the items you need for your everyday life. Sheets, pesetas, cooking utensils, etc. Within 200 meters from the house there are minimarket, pharmacy, tavern, butcher shop. The apartment on the first floor and you do not provide an elevator. You'll be happy with the house and its amenities.

Top guest favorite
A light and airy living space is highlighted by a comfortable beige sofa positioned against a softly colored wall. A white coffee table sits in front, accompanied by a small potted plant. Sheer curtains allow natural light to brighten the room.
Home
4.95 out of 5 average rating, 20 reviews

Cozy home in Vernard

Renovated detached house in the city centre with capacious spaces and everything you need for an unforgettable stay. It has two beds and a sofa bed and can accommodate up to 5 people. It is just 2 minutes from the central market and square as well as the bus and taxi station. It offers direct access to all points of interest, such as the historic center, the castle, the archaeological museum, the port, Tsamakia beach and all the busy places worth visiting.

Guest favorite
A bedroom features a spacious bed with neatly arranged linens. A wooden wardrobe stands against the wall, and a bedside table with a lamp offers soft lighting. A window allows natural light to brighten the pastel pink walls, and an air conditioning unit is installed above.
Home
4.77 out of 5 average rating, 48 reviews

Nostalgia Downtown House

Spacious two storey house in the center of Mytilene. Features a balcony with garden, 4 bedrooms with brand new air conditioners and can accommodate up to 7 people. Fully equipped as it features all kinds of home appliances and clothing. It is only a few meters away from the market of Mytilene and the port where you can find many taverns, restaurants and cafes. Ideal for families who want to spend a relaxing holiday on the island. (Reg. Number 200553)

Guest favorite
A scenic outdoor space showcases a pathway leading to a pool area, framed by olive trees and vibrant greenery. The blue waters of the bay are visible in the background, with hills rising gently along the shoreline under a partly cloudy sky.
Home
4.98 out of 5 average rating, 55 reviews

Twostorey house with amazing view (Aqua)

Πολυτελές διώροφο σπίτι 120 τ.μ. με ιδιωτική πισίνα και με θέα στον κόλπο της Γέρας,100 μ. από τη θάλασσα. Διαθέτει δύο υπνοδωμάτια, μπάνιο με υδρομασάζ,wc, σύστημα κεντρικου κλιματισμού, ενδοδαπέδια θέρμανση και wi-fi. Είναι κτισμένο μέσα σε ελαιώνα, έχει χώρο parking και είναι 5km από την πόλη της Μυτιλήνης το αεροδρόμιο και το λιμάνι. Σε απόσταση 5 km βρίσκονται οι γνωστές παραλίες Χαραμίδα και Άγιο Ερμογένη.

Top guest favorite
A modern kitchen features rich, burgundy cabinets contrasted with light wood lower cabinets. An integrated oven and cooktop are visible, along with a coffee maker, toaster, and essential kitchen items. The design incorporates a patterned tile floor, adding a touch of elegance.
Home
4.94 out of 5 average rating, 16 reviews

Modern House in Mytilene Center

The house is located in the city center, a short distance from supermarkets, pharmacy, bakery, central market, urban/interurban transport and taxi rank. Its location is ideal to get to know the city, to browse the traditional alleys of the central market with its shops, cafes and restaurants, just 500 m away. To visit its imposing castle and the beautiful organized beach "Tsamakia" at a distance of 1.3 km.

Superhost
The exterior showcases a two-story traditional building with maroon shutters framing the windows, which are adorned with white lace curtains. A small outdoor seating area features a patterned tablecloth, complemented by light-colored chairs, inviting relaxation in a serene setting.
Home
4.8 out of 5 average rating, 105 reviews

PanDesSia

"PanDesSia" is a traditional house in Mytilene, with Lesbian architecture. It is located in "Kayani", close by the famous "Antonis" Ouzeri. Offers a veranda with a fantastic view of the Aegean Sea, the town and the harbor of Mytilene and the Turkish coasts. It is only 6km from the town of Mytilene and 4km from the airport. It has two bedrooms overlooking the sea and can accommodate at least 4 people.

Guest favorite
A cozy seating area is positioned near large windows overlooking the sea. The stone wall adds a rustic touch, while two tall chairs with green cushions invite relaxation. Natural light floods the space, highlighting the nearby decorative items and the calm waters outside.
Home
4.88 out of 5 average rating, 17 reviews

Pelagia's House

Pelagia's house is a seaside house that was recently renovated while keeping its traditional character along with the memories of many carefree summers. The house has 2 bedrooms with one double and two single beds, fully equipped kitchen,very comfortable bathroom, air conditioning and wifi in all areas This beach house is perfect for a quiet and relaxing holiday.

Guest favorite
A rooftop terrace is visible, featuring black chairs and a table arranged on a patterned rug. The skyline is dominated by a church clock tower, adding architectural interest. A woven blanket is draped nearby, complementing the outdoor space against a bright blue sky.
Home
4.88 out of 5 average rating, 17 reviews

Casa De Pera Ermou

Casa de pera Ermou is an accommodation in the heart of the historical center of Mytilene. In our accommodation you will find a beautiful and elegant space with all the necessary amenities. Finally, the terrace of the house offers a view of the central market of Ermou with the highlight being the amazing bell tower with the clock of the cathedral church.

Top guest favorite
A logo for '4 Seasons Guest Room Mytilene' is displayed, featuring a stylized house silhouette against four colorful panels representing the seasons: green leaf, yellow sun, red maple leaf, and blue snowflake. The name is prominently presented in a bold font below.
Home
4.98 out of 5 average rating, 59 reviews

4 seasons

Fully furnished apartment 38 sq.m. in the quiet traditional settlement of Synoikismos, next to small local businesses (pharmacy, mini market, bakery, etc.) and just a few minutes away from the city center. Ideal for couples, this fully equipped apartment will satisfy your every need whether it is work or relaxation.

Guest favorite
A cozy living area features a brown leather couch and a woven chair. A wooden coffee table is positioned at the center. Exposed wooden beams accentuate the stone wall backdrop, while a lamp provides soft lighting for the space.
Home
4.94 out of 5 average rating, 49 reviews

Lesvos Exclusive Lounge, Mytilene City Center

Lesvos Exclusive Lounge is a classically restored home located in the center of Mytilene. Located on the ground floor, the 60-square meter home includes one bedroom, one bath, a fully equipped kitchen and a 20-square meter private yard perfect for enjoying your morning coffee or a good book.

Superhost
Home in Babakale
4.93 out of 5 average rating, 136 reviews

“İkiodabiravlu” Entire stone house with sea views

Our house, “iki oda bir avlu”, is situated in the beautiful, fishing village of Babakale, on the shores of the Aegean Sea. This historic village dates back to the 14th Century, and is famous for its castle, the last one built during the Ottoman Empire.

Popular amenities for Mytilini house rentals

When is the best time to visit Mytilini?

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Avg. price€ 45€ 49€ 52€ 55€ 68€ 69€ 77€ 90€ 72€ 47€ 44€ 46
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Quick stats about house rentals in Mytilini

  • Total vacation rentals

    Explore 90 vacation rentals in Mytilini

  • Nightly prices starting at

    Mytilini vacation rentals start at € 9 per night before taxes and fees

  • Verified guest reviews

    Over 1,890 verified reviews to help you choose

  • Family-friendly vacation rentals

    40 properties offer extra space & kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 20 rentals that welcome pets

  • Rentals with dedicated workspaces

    30 properties have a dedicated workspace

  • Wi-Fi availability

    90 of Mytilini vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Mytilini rentals

  • 4.8 Average rating

    Mytilini stays are highly rated by guests—averaging 4.8 out of 5!

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