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Vacation rentals in Mississippi River

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Top-rated vacation rentals in Mississippi River

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
The living area features warm wooden walls and a high, exposed beam ceiling. Comfortable seating is arranged around a patterned area rug. A wall-mounted television is present, along with a small table and fishing gear, providing a cozy and functional space for relaxation.
Cabin in Salem

Blue Ribbon Trout Cabin at Montauk

SEE PROPERTY DESCRIPTION Enjoy your own personal park space with Current riverfront access. This cozy three bedroom, one bath cabin is uniquely situated on 3 acres within National Park land boundaries just outside one of Missouri's premiere trout parks. Montauk State Park is just minutes away You can take a float trip, swim in the clear cool waters of the Current river, relax by the riverside fire pit or just sit on the deck and take in the natural beauty of the Ozarks National Scenic Riverways

LocationFamilyAccuracy

4.96 out of 5 average rating, 134 reviews
Top guest favorite
A rustic home built of natural wood is framed by blooming pink trees and lush green grass. The structure features a spacious porch with seating, while large windows allow views into the inviting interior.
Farm stay in Steelville

Yeary Farms Milt's Place with Private Beach!

An Ozark Oasis in the middle of a working cattle ranch, this custom designed home offers deluxe comfort. With multiple decks, porches and views out every window, this home is the perfect getaway for romantic retreats, family and friends to relax and make memories, artists and writers to host workshops or retreats, or even the single person to just get away from it all. Good dogs welcome, $35 per dog per week, fee collected separately at time of check in. Look for Yeary Farms site for more info.

ValueFamilyBiking

4.98 out of 5 average rating, 174 reviews
Guest favorite
Cottage in Carthage

Private Lakefront Romantic Cottage w/Swimspa&sauna

This cozy cottage is for couples looking to escape from it all and regenerate on many levels. You'll have your very own steam shower ....check out the company description.... . "Featuring 10 acupuncture jets, sunken tub and a high efficiency steam engine, the 608P steam bath is designed to greatly increase your spa experience. Indulge yourself in a state of complete relaxation". You'll also enjoy the comfy bed, fully stocked kitchen, private deck and access to a Swimspa and sauna 100 ft away.

ValueFamilyAccess

4.96 out of 5 average rating, 495 reviews
Top guest favorite
A rustic cabin exterior is framed by lush green grass and trees. The wooden structure features a stone chimney and a distinctive blue door, with two large windows on the left. A simple stone path leads to the entrance, inviting relaxation in a natural setting.
Cabin in Chanute

The Blue Door Cabin

If you want a retreat where you can sleep in, slow down and savor nature's beauty, the Blue Door Cabin, tucked in surprisingly hilly oak and hickory woods, with a beautiful view of the pond, is your destination. Within two hours from Kansas City, Tulsa, Joplin or Wichita, and only 4 miles from Chanute Kansas, this preserved and revived cabin offers an easy getaway for city dwellers in need of a very affordable anniversary weekend, study or solitude retreat, or family hiking and fishing trip.

FamilyValueCleanliness

4.98 out of 5 average rating, 622 reviews
Top guest favorite
The treehouse sits elevated among trees, showcasing a spacious deck with circular windows. Leaves and twigs cover the ground, while a gentle stream flows nearby. A hammock is visible, inviting relaxation within the serene natural landscape.
Home in Fayetteville

A Luxury Treehouse Experience | Wood-Fired Cedar Hot Tub

Welcome to Whitetail & Pine, a Luxury Treehouse Experience. Nestled in the branches of two centuries old red oak trees and suspended 25 feet above Goose Creek, this arboreal abode offers a unique twist on traditional lodging. If you are seeking a rejuvenating getaway accented with the sights and sounds of nature, yet desire to be close to Fayetteville’s best restaurants and attractions, look no further than the Treehouse @ Whitetail & Pine. If you are on the fence, check out our reviews!

FamilyLocationSleep quality

5.0 out of 5 average rating, 340 reviews
Top guest favorite
A screened-in porch features two woven armchairs positioned around a small table. The view highlights a serene landscape with a lake and mountains in the distance, bathed in the warm colors of sunrise. A colorful rug adds a cozy touch underfoot.
Home in Mountainburg

Locust Mountain View

This unique place has a style all its own. 5 minutes off the interstate and you can wake up to the most beautiful sunrises and views that Arkansas has to offer. This home has all the amenities you are looking for while still making you feel like you are away from the rest of the world. In the master bedroom we have a king size adjustable mattress that you can set to your exact preference. We are a quick drive to Fayetteville if calling the Hogs and great eateries is more your style!

LocationFamilyWalkability

4.95 out of 5 average rating, 156 reviews
Top guest favorite
The treehouse structure is elevated, supported by stilts, with large windows that reflect the surrounding greenery. The exterior features a combination of wood finishes, and warm lighting casts a welcoming glow in the evening. The pathway leads through the natural landscape to the entrance.
Treehouse in Perryville

Private Treehouse Retreat | Hot tub

The TreeLoft is the first of two treehouses at BaseCamp—designed for cozy seclusion, romance, and rest. Nestled in a private forest just 1 hour from St. Louis, it blends upscale comfort with immersive nature, while still being 20–35 minutes from hiking, wineries, and dining. ✨Our NEW treehouse, The TreeRise, offers an even more elevated, spacious experience at BaseCamp. Perfect for romantic getaways, anniversaries, personal retreats, and intentional escapes to unplug and reconnect.

LocationFamilyGrill

5.0 out of 5 average rating, 722 reviews
Top guest favorite
Treehouse in Jasper

Sunrise + Mountain Views • Firepit • Buffalo Hikes

Welcome to Canyon View Treehouse! Indulge in a unique and unforgettable stay at our Canyon View Treehouse. Located in the heart of Arkansas, you'll be surrounded by gorgeous mountains and spectacular views of the Arkansas Grand Canyon. Take a moment to relax and unwind on the spacious balcony, where you can sip on a cup of coffee while soaking in the natural beauty of the area. At Buffalo River Vacations our goal is to go above & beyond so our guests have an unforgettable getaway!

ValueFamilyRiver

4.98 out of 5 average rating, 240 reviews
Top guest favorite
The cottage is nestled among dense trees, featuring a welcoming front porch with white railings. Large windows allow natural light to enter, while a set of stairs leads up to the entrance. The surrounding greenery creates a serene, secluded atmosphere.
Cottage in Wheatland

Cozy Woodland Cottage

This cozy cottage in the woods (completed in June 2017) is perfect for a couple seeking a romantic getaway, enjoying a honeymoon, or celebrating an anniversary. (The sofa is a full convertible bed, if others plan to share the 400+ sq. ft. space.) Located in the Lake Hill (formerly Shadow Lake) Golf Course neighborhood (course is currently closed) about a mile from the NW shores of beautiful Pomme de Terre Lake, and about 6 miles south of Lucas Oil Speedway.

LocationValueHiking

4.98 out of 5 average rating, 445 reviews
Top guest favorite
A park model home is positioned on a stone terrace, surrounded by lush greenery. Large windows offer expansive views of the surrounding landscape. A wooden deck with seating is visible, extending the living space outdoors, with a tranquil atmosphere conveyed by the scenic backdrop.
Cabin in De Soto

Paradise Point sleeps 2 Hot Tub

1 bedroom 1 bath with loft. Cozy home where you can see Paradise. This memorable place is anything but ordinary. Views for miles of the Mississippi River, bluff tops and you can soar with the Eagles. What a place to relax in the newly added hot tub while you enjoy the view in what is call "God's Country". This is promised to be a one of a kind view. The Deck with comfortable outdoor seating Located in the heart of WIsconsin's Driftless Region.

ValueLocationGetting around

4.96 out of 5 average rating, 162 reviews
Top guest favorite
The exterior of the treehouse is showcased, featuring a modern design with natural wood paneling and large floor-to-ceiling windows. Surrounding foliage displays autumn colors, enhancing the serene forest setting. A wooden deck leads to the entrance, complemented by minimal landscaping elements.
Treehouse in Branson

Luxury Lakeview Treehouse • Stunning Views • Lake

Welcome to Tree + House II at Indian Point! This modern, luxurious treehouse is designed to accommodate up to four guests and offers a serene retreat in a peaceful forest setting. Featuring stunning floor-to-ceiling windows, you’ll enjoy spectacular views of Table Rock Lake right from your cozy hideaway. Conveniently located just minutes from Table Rock Lake and Silver Dollar City, it’s the ideal destination for both relaxation and adventure.

FamilyLocationLaundry

5.0 out of 5 average rating, 109 reviews
Top guest favorite
A cozy outdoor seating area is highlighted by a gas fire pit, with flames dancing over a bed of stones. The distant horizon showcases a sunset with vibrant colors, while the private hot tub is visible nearby, surrounded by the open landscape.
Home in Carthage

The Perfect Retreat: Modern Tiny Home- Hot Tub

A cozy and romantic luxury tiny home with a private hot tub under the stars. Wake up with coffee on the porch swing, watch the sunset from the spa, and unwind by the firelight in the evenings. Designed for slow mornings, peaceful nights, and reconnecting — just outside Carthage and next to I-44, enjoy the countryside and easy access to town. Perfect for couples, solo retreats, or a small, restful escape.

LocationValueNearby

5.0 out of 5 average rating, 200 reviews

Popular amenities for Mississippi River vacation rentals

Free parking on premisesGymBBQ grillLaptop-friendly workspaceWifi

Mississippi River house rentals

Top guest favorite
Two blue mugs are placed on a glass-topped table overlooking the serene lake. The calm water reflects the surrounding tree-covered hills, creating a peaceful setting. Soft morning light illuminates the scene, enhancing the tranquil atmosphere of this lakeside retreat.
Home in Edwards

Rippling Point Lakefront House

FamilyLocationDecor

4.96 out of 5 average rating, 306 reviews
Top guest favorite
The treehouse is nestled among lush green trees, featuring an earthy exterior of muted green and brown tones. A steep, sloped roof complements the expansive deck with sturdy railings, providing a welcoming entrance with large windows that invite natural light.
Home in Branson

Treehouse in Branson 10 min to SDC

LocationValueCheckout

5.0 out of 5 average rating, 188 reviews
Top guest favorite
An open living area features a large sectional sofa arranged around a circular table. Natural light streams through expansive glass doors, leading to a green outdoor space. Wood accents highlight the walls, and a staircase with a metal railing is visible in the background.
Home in Norfork

Riverside R&R on White River

LocationFamilyLayout

4.99 out of 5 average rating, 100 reviews
Top guest favorite
Home in Cottage Grove

Tree House Luxury Stay

FamilyValueQuiet

4.98 out of 5 average rating, 743 reviews
Top guest favorite
Home in Lake Ozark

Casa Amor Pink A-Frame! Bachelorettes•Girls Trips!

FamilyLocationGrill

4.97 out of 5 average rating, 199 reviews
Top guest favorite
A charming A-frame cabin is partially obscured by lush green foliage, showcasing a wooden deck adorned with soft lighting. Large windows reflect the surrounding nature, creating a seamless connection between the interior and the outdoors.
Home in Lampe

Views! Luxury A-Frame: Private Hot Tub & Fire Pit!

LocationFamilyQuiet

4.97 out of 5 average rating, 186 reviews
Top guest favorite
The exterior of a rustic country home is surrounded by trees and natural landscaping. A gravel pathway leads to the entrance, where wooden textures and stone accents create a harmonious connection with the environment. Curved architectural features and greenery enhance the inviting aspect of the home.
Home in Parthenon

Creek's End Riverside Retreat

LocationFamilyHiking

4.92 out of 5 average rating, 196 reviews
Top guest favorite
Home in Joplin

Inground Pool/Hot tub/GameRoom

ValueLocationKitchen

4.89 out of 5 average rating, 109 reviews

Other great vacation rentals in Mississippi River

Top guest favorite
The treehouse, elevated 35 feet in the air, features a natural wooden structure with a thatched roof. Surrounding greenery includes tall trees and lush plants. A wooden sign reading 'Tropical Treehouse' is positioned in the foreground, complemented by a small, nearby covered seating area.
Treehouse in Arkadelphia

The Treehouse is a quiet and peaceful retreat.

FamilyValueHospitality

5.0 out of 5 average rating, 260 reviews
Top guest favorite
The treehouse is illuminated at night, highlighting its modern architecture nestled among trees. Warm lights glow from the windows, contrasting with the dark sky. Surrounding foliage displays vibrant orange hues, adding a serene ambiance to the outdoor setting.
Treehouse in Hermann

Out On A Limb Treehouse

LocationValueQuiet

4.99 out of 5 average rating, 180 reviews
Top guest favorite
A spacious living area showcases wooden beams and walls, creating a warm atmosphere. Large, angled windows provide views of surrounding trees. Comfortable seating arrangements include a white sofa and two armchairs on a textured rug, complemented by a natural stone fireplace offering a rustic touch.
Treehouse in Ozark

Treehouse in the Ozarks w/Hot Tub, on 2 Acres

ValueLocationHot tub

4.98 out of 5 average rating, 275 reviews
Top guest favorite
A circular entrance leads into a spacious corridor, framed by glowing blue lights along the edges. In the background, a metal spiral staircase is visible, providing access to upper levels within the unique underground space.
Place to stay in Vilonia

Luxury Titan II Nuclear Missile Complex

LocationValueHospitality

5.0 out of 5 average rating, 363 reviews
Top guest favorite
A serene landscape is depicted, featuring rolling hills and valleys shrouded in morning fog. Soft hues of pink and orange fill the sky at dawn, creating a tranquil atmosphere. Lush greenery is visible in the foreground, adding depth to the scenic view.
Cabin in Ponca

Lost Valley View Cabin

ValueFamilyPets

4.96 out of 5 average rating, 648 reviews
Top guest favorite
A modern cabin features a wooden deck with a railing, set against a backdrop of trees. A six-seater UTV is parked in front, showcasing its utility for outdoor activities. The exterior is designed with a combination of dark wood and large windows, enhancing natural light.
Cabin in Strafford

River Cabin/UTV/Trails/Kayaks/HotTub/OutD Shower

FamilyValueAmenities

4.98 out of 5 average rating, 320 reviews
Top guest favorite
A rustic cabin exterior features wooden logs and stone accents, seamlessly integrating with the natural surroundings. A set of steps leads to a welcoming porch equipped with two wooden chairs for outdoor relaxation. Lush greenery and trees frame the cabin, enhancing the secluded atmosphere.
Cabin in Broken Bow

Couples Cabin/Hot Tub/Fire Pit/Peaceful/Private

ValueLocationNearby

4.96 out of 5 average rating, 259 reviews
Top guest favorite
A secluded cabin is nestled among tall trees, surrounded by lush greenery. Warm outdoor string lights illuminate the deck, creating a cozy ambiance. A prominent red 'NETFLIX' sign is visible on the cabin, indicating options for entertainment. Gravel pathways lead to the entrance.
Cabin in Broken Bow

*Movie Under the Stars + HotTub/Sauna/ColdPlunge

ValueFamilyIndoor spaces

4.98 out of 5 average rating, 125 reviews

Frequently Asked Questions

  • Where is Mississippi River located?

    The Mississippi River winds through the central United States, passing through states like Minnesota, Wisconsin, Iowa, Illinois, Missouri, Kentucky, Tennessee, Arkansas, Mississippi, and Louisiana before reaching the Gulf of Mexico. Its banks host diverse communities and landscapes shaped by the river.

  • When is the best time to visit Mississippi River?

    Late spring and early fall are frequently suggested, as temperatures are milder and local events often take place. Summer provides lush scenery but can feel humid, while winter attracts those interested in quieter river landscapes.

  • What are some things to do near Mississippi River?

    You can explore riverfront parks, nature trails, and historic sites, or join boat tours to learn about local wildlife and history. The area also has museums, cultural events, and opportunities for fishing or paddling.

  • How is the weather near Mississippi River?

    Winters are generally cold, ranging from 22–44°F (-5–7°C), while summers reach 83–88°F (28–31°C) with humid conditions. Spring and fall are often recommended for milder temperatures and changing scenery along the river.

Destinations to explore