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Vacation rentals in Mesopotamia

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Top-rated vacation rentals in Mesopotamia

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Guest favorite
A panoramic view captures the surrounding mountains and lush landscapes, with a mix of greenery and water bodies visible below. La Piedra de Peñol is prominently featured on the right, overlooking the expansive reservoir and hills stretching into the distance under a bright blue sky.
Treehouse in El Peñón de Guatapé
4.94 out of 5 average rating, 123 reviews

Treehouse in El Peñol - 360° views of stone

Enjoy the sounds & privacy of nature at this unique cabin in the trees ATOP the closest mountain to Piedra de Peñol. *IMPORTANT NOTES!* Though nicely located in nature, IT'S A TREEHOUSE CABIN IN & ON TOP OF MOUNTAINS, not a resort downtown. *PRICES CHANGE DEPENDING ON NUMBER OF PEOPLE (AB&B's POLICY!) Located as high as La Piedra de Peñol with better views than from the rock as you're able to see it as well! The cabin's isolated away from roads, noises of civilization & surrounded by reserves.

Top guest favorite
A freestanding tub is positioned near large windows, offering expansive views of the mountains and sunset. The serene bathroom features tiled flooring and a woven basket, creating a calm and spacious environment.
Home in Vereda El Zancudo
5 out of 5 average rating, 23 reviews

Luxury Finca With Pool, Sauna & Home Theater

Come and relax on the outskirts of Fredonia with your family. The property features: Swimming pool 4K Cinema Private Sauna Natural water springs & creeks Lakes with Mini-waterfalls Spacious kitchen Dining area for 8 Yoga studio Luxury beds & pillows Private bathroom for each bedroom 100mb/s Starlink Wi-Fi Workspace The property is dog-friendly, but there are no fences. There are 2 dogs living on the property. Salome y Luis-Javier. The property is not suitable for children under 10 years old.

Top guest favorite
Tiny home in Peñol
4.97 out of 5 average rating, 251 reviews

Foresta 2: Modern cabin with views of the rock

FORESTA 2 is a modern cabin created with love for you to have an unforgettable stay in the middle of nature with total comfort. Enjoy the privileged views from the bedroom and deck, relax in the warmth of the jacuzzi, watch the dozens of birds that visit us and chill out on the trampoline net. FORESTA 2 is a great launchpad to explore Guatape, climb the rock and do kayaking, jet-ski, wakeboard, sailing, paraglading, horseback riding, hiking, getting a helicopter ride or having an ATV tour.

Top guest favorite
Tiny home in Cocorná
5 out of 5 average rating, 14 reviews

luxury cabin with sauna, jacuzzy and private river

Enjoy the beautiful nature and tranquility of this luxurious accommodation with a sauna, jacuzzi, and private river terrace. Just 75 minutes from Medellín, this beautiful cabin is easily accessible by any car or motorcycle. The spectacular surroundings of Cocorná have much to offer, including paragliding, rafting, quad biking, and hiking trails along beautiful rivers. We are happy to assist you with transport or activities. We offer private transport from the airport! Includes breakfast!

Guest favorite
Cabin in Rionegro
5 out of 5 average rating, 31 reviews

The Ultimate Group House w/ Hot Tub & Amazing View

About this space 🌟 2 bedrooms, each with a double bed & private bathroom 🛏️ Double sofa bed in the living room 🛋️ Bathrooms with hot water & fresh towels 🚿 Living room with Smart TV & WiFi 📺 Private jacuzzi for relaxation 💦 Fully equipped kitchen 👩‍🍳 Gas BBQ grill for cookouts 🍖 Catamaran net, dining table & spacious deck/terrace 🌞 Private parking space 🅿️ Portable heater available 🔥 Breakfast available upon request, prepared by our staff with extra cost 🍳

Superhost
A modern cabin with a unique arched design is set against a vibrant sunset sky. The entrance features large glass doors framed by black accents, while the surrounding landscape showcases rolling hills that extend into the distance.
Cabin in La Ceja
4.84 out of 5 average rating, 44 reviews

Casi Cielo! Heaven's Edge

Nestled 7,000 feet high, our tranquil cabin promises breathtaking mountain and waterfall vistas. This retreat, perfect for romantic getaways or family escapades, enchants with its warming fire pit and rejuvenating hot tub. Experience the stunning wilderness, bask in the magnificent scenery, and craft unforgettable memories. This is not just a stay, but an experience enveloped in serene beauty, embracing the extraordinary amidst the ordinary. (500 characters)

Top guest favorite
A modern structure emerges from lush greenery, framed by vibrant plants and a manicured lawn. Large glass doors lead to a spacious deck, offering a view of the mountains and a colorful sky. Pathway stones create a welcoming entrance.
Home in La Ceja
4.93 out of 5 average rating, 44 reviews

Country house, excellent location, beautiful view!

We invite you to enjoy a beautiful space surrounded by nature, with all the comforts so you can relax and rest. You will feel like you are right at home. Ideal place for telecommuting (digital nomads) and long stays. Just 10 minutes from La Ceja, 45 minutes from the international airport and about 1 hour from Medellin. Pets are welcome. Additionally we offer Yoga classes and Ayurvedic therapies (Abhyanga/Swedana). Perfect place for "slow" tourism!

Top guest favorite
The cozy cabin is nestled in a lush green landscape, illuminated by warm outdoor lights. A wooden deck features comfortable seating, overlooking the serene surroundings. Large windows provide a glimpse of the interior, showcasing a warm and inviting space harmonized with nature.
Farm stay in Rionegro
4.95 out of 5 average rating, 279 reviews

Lumberjack's House | Secluded nature retreat

🪓 Retreat Cabin – Lumberjack's House is our dream home. A small, cozy tiny home surrounded by nature. The perfect place to spend a few days as a couple, a family weekend or work remote in a distraction-free environment. Wake up to the singing of the birds at sunrise and enjoy a fire on the deck at sunset. In Retiro Cabin you will have total independence and an unparalleled view of the countryside in the Antioquia East.

Top guest favorite
Chalet in Antioquia
4.96 out of 5 average rating, 283 reviews

Cabin with Jacuzzi 8 min from JMC Airport

Welcome to Quimera Ecolodge, a charming chalet located in a natural paradise paradise just 10 minutes from José María Córdova Airport. At Quimera Ecolodge, every corner has been designed to offer you a unique experience, combining comfort, sustainability, and an authentic connection with the natural environment, ideal for those who want to escape the hustle and bustle of the city without losing proximity to comfort.

Top guest favorite
A bright workspace features a wooden desk with a comfortable ergonomic chair and modern lamp. A hammock hangs nearby, surrounded by lush greenery. Large glass windows invite natural light and offer scenic views of the surrounding trees, creating a serene and productive atmosphere.
Cabin in Santa Elena
4.99 out of 5 average rating, 228 reviews

Tree Life Cabin, Saint Helena

A place to be in touch with nature from the comfort. Experience rest and tranquility in a space that opens up among the trees. Enjoy a landscape that changes between fog, rain, and a gentle sun. Santa Elena is a rural mountain area outside of Medellín, 19 km from downtown or 13 km from JMC Airport. The cabin is located near bus routes, restaurants, mini-markets, forest trails, and tourist attractions.

Top guest favorite
An outdoor deck is shown, featuring a spacious jacuzzi surrounded by lush greenery. Sunlight filters through trees in the background, highlighting the serene environment. Two comfortable chairs are positioned nearby, inviting relaxation in the natural setting.
Cottage in Retiro
4.93 out of 5 average rating, 109 reviews

Country house with outdoor hot tub

Beautiful house, with wide and cozy spaces, full of natural light, perfect to get away from technology and the noise of the city, relax in a spectacular outdoor Jacuzzi and then enjoy a night at the fireplace. The sound of the small stream invites you to rest and enjoy nature: bird watching, resting on the grass, feeling the rain and the sun, dreaming under a sky.

Top guest favorite
A secluded cabin is nestled amongst lush greenery, surrounded by a variety of trees and plants. The structure features a simple design with a pitched roof and large windows that blend into the natural surroundings. A stone pathway leads to the cabin entrance.
Cabin in Rionegro
5 out of 5 average rating, 10 reviews

Cabin in the mountains

Enjoy a one-of-a-kind experience in this cozy cabin surrounded by forest. Perfect for disconnecting, relaxing and enjoying nature with all the amenities: fireplace, large windows, equipped kitchen and private bathroom. Ideal for romantic or family getaways, just 10 minutes from the main road. 🌲✨

Popular amenities for Mesopotamia vacation rentals

  1. Airbnb
  2. Colombia
  3. Antioquia
  4. Mesopotamia