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Guesthouse vacation rentals in Madre de Dios

Find and book unique guesthouse rentals on Airbnb

Top-rated guesthouse rentals in Madre de Dios

Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

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Guesthouse in Urubamba
4.87 out of 5 average rating, 38 reviews

Casa de Campo

Small apartment in the middle of a fruit and flower garden; with everything necessary for a comfortable stay. Total area: 45 m2, floor and half of construction. First Floor: Living room, kitchen and bathroom (hot water on the shower with gas terma). Second floor: Room and a balcony that overlooks the mountains. Clay, stone, wood, and ceramics finishes. Wide windows, as well as a skylight on the ceiling, provide natural light throughout the day. Pd. Guests can be picked up from Cusco (airport or hotel) in our mobility and take them to the house in Urubamba for an extra cost. Consult

Guest favorite
Two individuals are seated on a wooden boat, overlooking a lush green landscape along a tranquil river. The water reflects the surrounding greenery and sky, while dense foliage and trees frame the scene. Binoculars are being used to observe the natural surroundings.
Guesthouse in Madre de Dios
4.87 out of 5 average rating, 54 reviews

Jungle house in Manu National Park.

Jungle House, en Villa Salvación en la biosfera del Parque Nacional del Manu, dispone de una habitación triple , habitación matrimonial con cama king, jardín, cocina - comedor, sala y baño con ducha caliente, a solo 25 min. caminando a cocha Machuwasi, fantástico lugar natural con muchas aves y monos, esta a solo 30 minutos en auto del centro de rescate de fauna silvestre y el jardín de picaflores, a 1 hora de la comunidad de Shintuya, de las aguas termales y a solo 6 horas de Cusco. 5 pax.

A wooden dining table is accompanied by four chairs, set against a rustic stone wall. A vase with fresh flowers sits at the center of the table, while two simple framed artworks are displayed on the wall, enhancing the cozy dining area.
Guesthouse in Ollantaytambo
4.81 out of 5 average rating, 298 reviews

Department Ollantaytambo NunaSumaq

Nuestro alojamiento es cálido, cómodo, muy tranquilo y todo está bien amoblado. Estámos ubicados a 4 minutos de la Plaza de Ollantaytambo (caminando) , entre las calles Incas unicas del lugar. (calles empedradas). El alojamiento es privado de los huéspedes por el tiempo que confirmen su reserva. Con servicio de internet de alta velocidad y buen sistema de agua caliente. Le encantará la vista desde nuestra terraza, podrá ver todo Ollantaytambo de dia, y en la noche el cielo maravilloso.

Guesthouse
New place to stay

Quiet Sanctuary in Peru’s Sacred Valley

This quiet bungalow is a true sanctuary — a safe haven held by the mountains of Peru’s Sacred Valley. Perfect for travelers seeking stillness and reflection, it offers peace and a feeling of deep protection. The space has been lovingly prepared to nurture your spirit, with thoughtful touches like warming teas, fresh fruit, bread, and local honey to welcome you on arrival. A place to rest and to reconnect — just a short journey from Cusco yet far away from noise and distraction. 🌿✨

Guest favorite
A cozy sleeping area features a spacious bed adorned with crisp white linens and a colorful decorative blanket. Two lamps provide soft lighting on either side, while a decorative wall hanging adds cultural charm. A staircase leads to another level, enhancing the room's depth.
Guesthouse in Cusco
4.97 out of 5 average rating, 67 reviews

Cozy Studio Sacred Valley Urubamba Cusco.

A comfortable well equipped room with breakfast bar and basic appliances for simple meals. This independent space for two, queen bed plus futon. Private entrance, Satellite TV, internet, Barbque and outdoor dining area. Share our gorgeous gardens, glass yoga room in the woods and pool with mountain views. Need a larger space check out our cottage on the same property, book the studios own guest suite for another couple! Cottage listing is: airbnb.com/rooms/1030483

Guest favorite
A cozy sleeping area is presented with two spacious beds, each adorned with distinct bed linens. A patchwork quilt covers one bed, while decorative pillows add a touch of comfort. Nightstands with lamps are positioned beside the beds, and a wooden herringbone floor is visible.
Guesthouse in Urubamba
4.97 out of 5 average rating, 78 reviews

House with bathroom/full kitchen/bedroom 04 people

La Casita in Yanahuara is the perfect place to disconnect from the world and be in touch with nature! We are a 15-minute walk from the nearest main road, in an agricultural area, resulting in an ideal balance between escape from the city and proximity to services. The house has a bathroom, hot water, a fully stocked kitchen, a high-quality double bed, and access to the patio and garden where you can enjoy the scenery, local birds, and even a nighttime barbecue/bonfire!

Guest favorite
The exterior of the cabin is showcased, featuring a vibrant orange facade with large windows that allow for ample natural light. A well-maintained garden path leads through lush green grass, flanked by native plants and shrubs. The surrounding landscape includes hints of the Sacred Valley.
Guesthouse in Urubamba
4.9 out of 5 average rating, 29 reviews

Mountain view & garden cottage, toward MachuPicchu

In the heart of Urubamba, en route to Machu Picchu, our cabin offers stunning views of the Andes and a peaceful retreat in nature. Enjoy disconnecting from city life in this charming corner of the Sacred Valley, while being just minutes from town amenities. Experience comfort in a warm, family-friendly environment featuring a cozy fireplace and a delightful garden terrace—perfect for exploring the valley, discovering Machu Picchu, and unwinding in tranquility.

A charming two-story bungalow with a yellow exterior is surrounded by lush greenery and colorful flowers. A stone walkway leads to the entrance, with a small stream running nearby. The roof features traditional tiles, adding to the rustic appeal of the property.
Guesthouse in Urubamba
4.74 out of 5 average rating, 27 reviews

Cozy and beautiful little house in the Urubamba Valley

Cozy two-story cottage in the Urubamba Valley. Located within a property with large gardens and vegetation. Suitable for family or friends groups who prefer to have their own space when traveling to the area. An environment conducive to rest, relaxation and disconnection will allow a unique rest. The bungalow has all the necessary amenities, from kitchenware to electronic appliances that will allow a pleasant stay for all people staying.

Guest favorite
A cozy living area features a red sofa and two green chairs arranged around a round wooden table. A woven rug sits beneath the table, and a vibrant blue door provides natural light into the space. Wooden floors add warmth to the room.
Guesthouse in Urubamba
4.89 out of 5 average rating, 9 reviews

Cozy apartment in Urubamba

The apartment has a beautiful view of the Vilcanota River. The apartment is fully equipped and with all the amenities. Through an outside door you have access to a beautiful orchard to enjoy nature with fruit trees and many flowers. The dining room, kitchen and bathroom is new construction. It has a washing machine and clothesline with hot and cold water installation. It has an interior garden with a pergola with armchairs to rest.

Guest favorite
A charming bungalow features a stone exterior and wooden shutters on large windows. The roof is tiled, and flowers are seen in the foreground, adding a splash of color. Surrounding trees and mountains create a serene natural setting.
Guesthouse in Urubamba
5 out of 5 average rating, 21 reviews

Stunning bungalow in the heart of the SacredValley

Hermoso lugar para descansar y recargar energías en el Valle Sagrado. Este acogedor bungalow tiene todo lo necesario para tener una bonita estancia. Cuenta con sala/comedor con chimenea, un dormintorio con cama queen, baño completo y cocina equipada. Está rodeado de bonitos jardines e imponentes montañas y en las noches las estrellas acompañarán tus noches de fogata.

Superhost
The image captures a charming garden area behind a rustic wall, adorned with potted plants and decorative lanterns. The lush green lawn is bordered by a stone pathway, leading to colorful flowers. Rolling hills are visible in the background, adding to the tranquil setting.
Guesthouse in Calca

Dream House in the Sacred Valley of the Incas

🏡 Escape to the Sacred Valley and experience unique moments in this cozy cottage in Huaran-Calca. Enjoy hotel-style rooms, equipped kitchen, organic orchard, living room with fireplace, fast Wi-Fi, games such as pool, ping pong and frog, hot water 24/7, night campfire and meals in a Chinese box. Ideal for families and groups looking for disconnection and comfort

Superhost
A bright room features two spacious beds, each adorned with patterned bedcovers in floral designs. Natural light enters through a large window, framed by white curtains, illuminating the cozy atmosphere. A small table with chairs is situated near the window, enhancing the inviting layout.
Guesthouse in Urubamba

Family Room in Casa de Campo - Urubamba

Our country house is located in the rural area of the city of Urubamba in the Sacred Valley. Built of adobe, stones and wood, we have all the comforts of a modern house. We are located at the foot of Saywa Mountain in a historical area, close to the archaeological site of the "Palacio del Inca Huayna Capac".

Popular amenities for Madre de Dios guesthouse rentals

Kitchen
Wifi
Pool
Free parking on premises
Air conditioning

Family-friendly guest house rentals

An arched entrance with colorful murals welcomes visitors to the property, framed by stone walls and mountain views. The vibrant artwork features tropical birds, enhancing the natural backdrop. A rustic building is visible beyond the gate, surrounded by gardens and greenery.
Private room in Ollantaytambo

Triple bed cabin

A modern structure featuring large glass windows that provide ample natural light and views of the surrounding greenery. Steps lead from the grassy area to the entrance. The landscape includes blooming flowers and trees, contributing to a peaceful ambiance.
Private room in Calca

HananPacha-Ashram Transpersonal

A bright room features large windows with flowing curtains, allowing natural light to illuminate the space. A spacious bed is adorned with a vibrant floral blanket. Minimalist furnishings, including a small table and chairs, are positioned at the far end, offering a tranquil atmosphere.
Private room in Puerto Maldonado
4 out of 5 average rating, 4 reviews

Comfortable, safe and spacious rooms

A spacious room features wooden beams across the ceiling and a parquet floor. A round table with a white tablecloth and four black chairs is present, alongside a bed with colorful blankets. A large window invites natural light, with a door leading to another area.
Private room in Calca

NuNaTiKaY Healing House

A spacious bedroom is highlighted by a large, upholstered bed with crisp white linens and decorative pillows. Bright floral murals adorn the walls, complemented by wooden furniture, including a small desk and a chair. A glass door leads to an adjoining area, enhancing the open layout.
Private room in Urubamba

Your home away from home!

A spacious bedroom is furnished with a bed covered in a striped blanket. A wooden table is positioned nearby, and a television is mounted on the wall. Light hardwood flooring and pale walls create a bright and open feel.
Private room in Tambopata

I rent out furnished rooms

A pathway leads through a garden towards a two-story house, flanked by vibrant green plants and blooming flowers. Sunlight filters through the wooden balconies, enhancing the natural beauty of the setting. The surrounding mountains provide a serene backdrop.
Private room in Urubamba

Yogis House Urubamba

A wooden dining table is surrounded by six matching chairs, set against a backdrop of textured stone walls. A glass vase filled with colorful flowers sits at the table's center, while natural light enters through partially closed curtains.
Private room in Ollantaytambo

Accommodation with an incredible view

Guest house rentals with a patio

Guest favorite
Natural light fills the room through a large window overlooking a palm tree. A simple bed is positioned against one wall. Light-colored curtains frame the window, and wooden flooring extends across the space, enhancing the bright atmosphere.
Private room in Tambopata
4.78 out of 5 average rating, 9 reviews

Private room + bathroom w/ shared spaces

A cozy bedroom is featured, showcasing a spacious bed adorned with a textured white coverlet. Natural light filters in through a large glass door, which leads to a serene outdoor area with greenery. Decorative elements include soft curtains and a unique light fixture.
Private room in Urubamba

SamAymara - Pacha Room

A colorful promotional flyer showcases an exploration tour of Manu National Park. Highlights include bird watching, jungle hikes, hot springs, and river swimming, along with accommodations detailed for a comfortable stay. Images of lush greenery and wildlife are presented, promoting an immersive rainforest experience.
Guesthouse in C.p Salvacion

Coco's House

A warm-hued room features a spacious bed adorned with a colorful, fringed throw. A small bedside table sits next to the bed, complemented by a decorative vase. Textured wall accents add character, while soft natural light filters in through the window.
Private room in Calca

Room 2 in Beautiful Guest House

A spacious living area features two large sofas and a sectional, arranged around a coffee table. Natural light enters through several windows. A dining table with chairs is visible, along with a cozy rug and decorative plants accentuating the rustic charm.
Guesthouse in Urubamba

House Accommodation Valle Sagrado Urubamba Cusco

Guest favorite
The vibrant exterior of the eco lodge is adorned with colorful murals, surrounded by lush greenery and flowering plants. A wooden picnic table and a tall stool are placed on a manicured lawn, framed by trees and the distant mountains in the background.
Private room in Ollantaytambo
4.86 out of 5 average rating, 28 reviews

Full Moon Eco Lodge: Chaska 3

A minimalist bedroom features a spacious bed with a chocolate brown headboard and crisp white linens. A small desk is positioned against the wall, and a wall-mounted television is visible. Natural light filters through sheer curtain panels, enhancing the room's bright appearance.
Private room in Ollantaytambo
4.67 out of 5 average rating, 3 reviews

Casa Esteves: Charm in Ollanta

A wooden sign for 'Hospedaje Mapi Wasi' is displayed prominently. The lettering is artistic and bold, set against a backdrop of textured wooden panels. Simple decorative elements, including small leaves, enhance the rustic appeal of the sign.
Private room in Urubamba

Hospedaje MapiWasi

Other guesthouse vacation rentals

Superhost
A spacious room is captured featuring a large bed dressed in white linens, complemented by decorative pillows. A chair is positioned nearby, next to a small table with a lamp. Natural light filters in through small windows, illuminating the warm color scheme and rustic wooden beams.
Private room in Yucay

Double room with private balcony. De Alba.

A simple room is depicted, featuring a wooden ceiling and a ceiling fan. A wooden closet with drawers is visible, along with an open door leading to another space. Natural light enters through a window on the opposite wall.
Private room in Puerto Maldonado

Rooms in Puerto Maldonado

Superhost
A bright room features two individual beds with soft white linens, positioned beside wooden bedside tables. A cozy armchair is present, and natural light enters through a nearby window, enhancing the room's airy feel. Two wooden doors lead to additional private areas of the villa.
Private room in Yucay

Cozy Double room with separate beds. De Alba

Superhost
A spacious room showcases a wooden floor and large windows with natural light. A dining area with two decorated chairs and a low table is situated beside a staircase. The room's design includes warm tones, enhancing the overall inviting ambiance.
Guesthouse in Sacred Valley
4.5 out of 5 average rating, 4 reviews

Light Wood - Cabin 2

Superhost
An open and airy room features two spacious beds with soft linens in light tones. Natural light filters through large windows overlooking the garden. A wooden ceiling with exposed beams adds character. A small dining table and chairs are present, enhancing the cozy ambiance.
Private room in Yucay

Double room in the Sacred Valley. De Alba

Guest favorite
A colorful two-story building is highlighted with vibrant murals on its exterior. The surrounding garden features lush greenery and orange flowering plants. A picnic table and stool are visible on the lawn, providing a space for relaxation amidst nature.
Private room in Ollantaytambo
5 out of 5 average rating, 6 reviews

Full Moon Eco Lodge: Maiu 2

Superhost
An open space featuring wooden flooring and natural light from skylights. A cozy seating area with two patterned chairs complements a wooden table set with dishes. A staircase leads to an upper level, while a small kitchen area is visible in the background.
Guesthouse in Sacred Valley
5 out of 5 average rating, 5 reviews

Light wood - Cabin 3

A cozy room features a spacious bed with a colorful blanket. Natural light enters through the large window, revealing views of the surrounding mountains. The walls are painted in a warm pink, and a bedside table is adorned with a small vase and a lamp.
Private room in Ollantaytambo

Double Room with Mountain View

Destinations to explore