
Pet-friendly vacation rentals in Lee County
Find and book unique pet-friendly homes on Airbnb
Top-rated pet-friendly home rentals in Lee County
Guests agree: these pet-friendly homes are highly rated for location, cleanliness, and more.

Separate private entry Duplex
Sound proofed half-duplex. Private entry and parking. Entire separate living space on back of property. 10 min to downtown Tupelo, 7 to Veterans Park, 15 to Barnes&Noble. Full kitchen, clean dishes & utensils, Oven, hand-built tile shower, washer/dryer, large fridge with water/ice, microwave, coffee maker, WiFi, TV, Queen bed. 2x Window AC with heat. Self checkin/out. All pets welcome! Bed + futon for up to 4. This unit will transition to a long term rental in Dec @950/m with utilities included
4.86 out of 5 average rating, 78 reviews
Green St. Cottage
This charming home is set in historic Mill Village. Tucked neatly in downtown Tupelo, it is within walking distance to dining, shopping, arena's & more. Inside you will find a newly renovated space, offering 2 bedrooms with King size beds, TVs & blackout curtains. The kitchen is stocked with basic essentials such as dishes, cookware, and utensils. Coffee/tea, sugar and cream are provided as well. The Living Room is a cozy space with a TV & electric fireplace. please read house rules
4.98 out of 5 average rating, 119 reviews
Tupelo Hospitality Hideaway
Relax in this renovated hideaway centrally-located in the heart of Tupelo, MS. Whether for work, play or just passing through, this unit offers 2 generously sized bedrooms w/queen size beds, smart TVs in each room & each bedroom has an on-suite bathroom. The property is minutes from Ballard Park Sportsplex, Veterans Park Sportsplex, Tupelo Aquatic Center, Downtown Tupelo, Cadence Bank Arena & Elvis Presley Birthplace too! Restaurants, shopping and grocery stores are located minutes away.
4.89 out of 5 average rating, 114 reviews
Spacious, historic downtown bungalow. Sleeps 10!
The whole group will enjoy this central location in Tupelo! Walk to downtown Tupelo or take a quick drive to Elvis' birthplace. Family park across the street or enjoy your own large yard. Each room has T.V.'s and a huge closets. Master bath has jetted tub. Large kitchen is stocked with all the essentials. This property is pet friendly for 1 dog ($20/night). Please contact me for additional pets. The home sleeps up to 8 adults and 2 children. Bunks are for kids only due to weight.
4.97 out of 5 average rating, 196 reviews
The Lakehouse at Colline Rouge (Red Hill)
Lake house Living with this spacious 4 Bedroom 2 Bath Location right on the edge of Tupelo,MS. Enjoy watching Deer and Turkey from the Back porch with Fireplace Both Inside and Out with Beautiful View of the 16 Acre Lake. Roomy Kitchen, Great for Family outings or Couples Gettaway. There are King size beds in 2 Bedrooms and a Queen Sized in the 3rd. In the 4th BR there are 2 Separate Bunks Beds.....(Full on bottom, twin on top with easy access steps, the 2nd bunk has a Full & Twin.
4.84 out of 5 average rating, 137 reviews
The Heights - Town & Country Living
Welcome to The Heights! For Starters, you will be greeted with a fresh pan of Talbot Cinnamon Rolls.* For stays three nights and longer, you will also find a cheese, meat, cracker platter in the fridge. The kitchen is equipped with a Keurig coffee maker(drip and K-Cup) with coffee! The fridge is stocked with water, juice and sparkling water. This 70's era home has been immaculately cared for and has the comfort of 3 Bedrooms, two bathrooms, Living Room, and a complete kitchen.
5.0 out of 5 average rating, 126 reviews
The Peaceful Pines Retreat
Welcome to Peaceful Pines Retreat 🌲 Escape the noise and experience the perfect blend of modern comfort and rustic charm at Peaceful Pines Retreat. Nestled among towering pine trees, this private retreat is the ideal place to unwind, reconnect, and make lasting memories with family and friends. Wake up to the peaceful sounds of nature, sip your morning coffee on the spacious front porch, and spend your evenings gathered around the fire pit under a sky full of stars. Inside,
4.82 out of 5 average rating, 22 reviews
The Sugar Shack Cottage
The Sugar Shack Cottage, with Hot Tub, King Bed New home Located in Historic Mill Town and near the famous rail tracks of Tupelo, step right on in and open the plantation shutters to a light and bright brand- new bungalow cottage filled with mid -century modern, bohemian and 70’s Hippy vibes. You will find a record player with some 70s and other good music, a few lava lamps, a salt rock lamp, and lots of conversation pieces. We are close to everything in downtown Tupelo.
4.96 out of 5 average rating, 122 reviews
Charming Saltillo Stay
Discover a peaceful escape at our home nestled in the heart of Saltillo. This charming home offers the perfect blend of comfort and convenience, ideal for those looking for a relaxing getaway. Our home is located in a quiet neighborhood and with a cozy backyard, this space is amazing to enjoy with friends and family. Less than 10 minute drive to the mall. 15 minute drive to NMMC hospital. Less than 15 minute drive to Elvis' birthplace and downtown.
4.95 out of 5 average rating, 38 reviews
Cozy Dog-Friendly Cottage Near Downtown Tupelo
Settle into comfort at this cozy, dog-friendly cottage near Downtown Tupelo and Elvis’ Birthplace. With fast WiFi, same-day check-in, and a peaceful neighborhood, it’s ideal for remote workers, family visits, and travelers headed to the coast. Enjoy reliable Superhost care, safe parking, and home-style amenities close to restaurants, shops, and Tupelo’s top attractions—a welcoming space designed for easy living and stress-free stays.
4.92 out of 5 average rating, 265 reviews
Historic Charm Near Downtown Tupelo
Newly remodeled historic home less than a mile from Downtown Tupelo where you can enjoy shopping and plenty of tasty restaurants. The house has been thoughtfully furnished in a fun, midcentury modern style. The beds are very comfortable and the master bathroom has a giant shower and separate soaking tub to enjoy after a long day. Please note the house is close to the famous downtown train so you may hear the engine horn at night.
4.97 out of 5 average rating, 468 reviews
Unwind at Swallow Lane
Unwind and enjoy easy access to everything from this centrally located home, here in Tupelo, Ms. It’s super spacious and chic, whether you’re cooking in the kitchen, relaxing in the living room, or enjoying the closed-in patio. It has a outdoor bar area, as well as a fenced in yard. We have card/ board games, cornhole boards, and a fools ball table. There's enough fun for the adults and the kids.
4.95 out of 5 average rating, 149 reviewsPopular amenities for Lee County pet-friendly home rentals
Pet-friendly house rentals

Magnolia Oaks Airbnb
4.96 out of 5 average rating, 24 reviews
Kirby’s Korner
4.95 out of 5 average rating, 21 reviews
Spring Street Cottage
4.89 out of 5 average rating, 9 reviews
Chaney Hill Hideaway
4.98 out of 5 average rating, 99 reviews
House Of Pearl!
4.85 out of 5 average rating, 39 reviews
Heart Break Bungalow Near Downtown +Elvis

Newly Renovated Historic Mill Village Cottage
4.93 out of 5 average rating, 221 reviews
Contemporary Charm near Elvis Presley’s Birthplace
4.82 out of 5 average rating, 188 reviewsPrivate, pet-friendly home rentals

Pontocola Pines Off Natchez Trace. Pontocola Rd.
4.97 out of 5 average rating, 35 reviews
Modern Condo 'N Heart of Tupelo
5.0 out of 5 average rating, 7 reviews
Whispering Pines Tiny Home RV
4.98 out of 5 average rating, 40 reviews
Tupelo Studio
5.0 out of 5 average rating, 9 reviews
Charming Chestnut Cottage-A Downtown Favorite!
4.96 out of 5 average rating, 136 reviews
Heart Break Hound Dog Bungalow - Downtown
4.85 out of 5 average rating, 13 reviews
D’Redbud Manor
5.0 out of 5 average rating, 4 reviews
Ole Rustic Cottage
4.53 out of 5 average rating, 38 reviewsPet-friendly home rentals with a hot tub

BudgetFriendly N’HeartOf Tupelo-6minsNMMC Hospital

Hollywood Bungalow
5.0 out of 5 average rating, 58 reviews
Home away from Home
4.98 out of 5 average rating, 153 reviews
The Lakehouse at Colline Rouge (Red Hill)
4.84 out of 5 average rating, 137 reviews
The Sugar Shack Cottage
4.96 out of 5 average rating, 122 reviews




