Vacation rentals in Lee County

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Top-rated vacation rentals in Lee County

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
Loft in Carthage
4.96 out of 5 average rating, 121 reviews

Huge Classy Upstairs Victorian Apt with Jetted Tub

The whole group will be comfortable in this spacious and unique space. With two queen sized beds and a set of twins under the attic skylights everyone will find a restful place to restore for the day. A relaxing jetted tub also provides a rainfall shower with 3 acupuncture jets. The kitchen is fully stocked with quality cookware. This vintage treasure was built in 1884 and is a completely renovated upstairs unit. There is 2 bedroom unit below this one and the option to share a washer/dryer.

Guest favorite
Cabin in Montrose
4.89 out of 5 average rating, 37 reviews

Grandpa's Fishing Cabin is Cozy!

Welcome to Grandpa’s Cozy Cabin, a peaceful retreat tucked right along the banks of the beautiful Mississippi River. A warm, rustic cabin with all the comforts of home, Gorgeous riverfront views perfect for sunrise coffee or sunset drinks, Outdoor seating, firepit, and space to unwind under the stars. A quiet, relaxing atmosphere. Great for a weekend getaway, family stay, or couple’s retreat. We offers the charm of simple living with the magic of the river right outside your door.

Top guest favorite
The exterior of a charming white house with a gray metal roof is shown, framed by a small tree and well-maintained lawn. The front porch features black shutters, and a welcoming entrance is visible. A spacious yard leads to a fenced area at the back.
Home in Fort Madison
4.92 out of 5 average rating, 73 reviews

Luxury on 21st

Take a break and unwind at this peaceful oasis. This 1 bedroom home has been recently refreshed with new carpet, paint, light fixtures, and more. Spacious living area with room for a blow up mattress. Bathroom Amenities include your basic linens and a hairdryer. The kitchen includes basic cookware for you to use during your stay as well as. The washer & dryer are available for use. Please help yourself to the game cabinet for activities. Fenced in backyard with a small patio area.

Guest favorite
A charming wooden treehouse is nestled among lush greenery, elevated on stilts with a welcoming entrance. A pathway made of wooden planks leads toward the structure, flanked by a decorative lantern and surrounded by vibrant foliage, creating an inviting atmosphere in the forest.
Treehouse in Nauvoo
4.96 out of 5 average rating, 177 reviews

Captains Quarters Treehouse

An off the grid whimsical gem in the Ten Acre Treehouse forest! "The Captains Quarters". This is the 2nd treehouse in rural Nauvoo. A lot of the same touches found in "The Whitetail". The first treehouse here, you will find in this nautical inspired creation. This treehouse is a full 2 story, 400 sq foot, and features second story bedroom, sleeper sofa on the first floor, small kitchen area with refrigerator/freezer, microwave, coffee maker, plates, silverware, cups and a sink!

Top guest favorite
Apartment in Fort Madison
5 out of 5 average rating, 58 reviews

Charming apt w/private deck

Enjoy a relaxing experience at this beautiful apartment located in historic downtown Fort Madison. Just a short distance from the train station you'll arrive to enjoy a private apartment in the second story of this refurbished home. All amenities required for a comfortable stay have been thoughtfully chosen and provided for you. Create a memorable meal in the well stocked kitchen before you relax on the deck to enjoy a view of the Mississippi River and Fort Madison Train Depot.

Top guest favorite
Guest suite in Keokuk
4.96 out of 5 average rating, 517 reviews

Tree of Life River Retreat

Located 1½ miles north of Keokuk, nestled on a bluff overlooking the Mississippi River, the Tree of Life River retreat is located in a cozy, private, walk-out lower level (with hosts living above). There's a private bedroom with a queen bed and another sleeping area with four twin beds, perfect for one person or a family. Relax, enjoy nature, and take advantage of our large backyard. We are located approximately 18 miles from downtown Nauvoo via the bridge in Keokuk.

Top guest favorite
Home in Fort Madison
4.97 out of 5 average rating, 39 reviews

cozy cottage

Tucked away in an area with quiet neighbors this serene cottage has a wonderful safe feeling. Close to historic downtown, the Mississippi, parks, the train station and the bridge, this is a great location. Twenty minutes from Nauvoo, this is one of the closest towns to Nauvoo with grocery stores and is just the right distance for the kids to fall asleep. With cobblestone roads and enchanting venues you are sure to fall in love with the Hallmark charm of Fort Madison.

Top guest favorite
An outdoor deck showcases a round table surrounded by four chairs with cushions. An additional chair is positioned nearby. A patterned rug lies beneath the table, providing a cozy area for relaxation. Distant green grass and trees can be seen in the background.
Home in Carthage
4.93 out of 5 average rating, 175 reviews

Nice 2 bedroom home w/attached garage & deck.

Nearby attractions in Carthage include historic Carthage Jail & Kibbe Museum, historical Carthage courthouse, public swimming pool & golf course, several public parks & library, shopping, restaurants, and the Legacy Theater. Many recreational activities & special events year round. Located just minutes from the interstate. 16 miles from Nauvoo, IL. 15 miles from Keokuk, IA. 27 miles from Macomb, IL. 43 miles from Quincy, IL. 59 miles from Hannibal, MO.

Guest favorite
A dining area features a round wooden table with a decorative bowl at its center. Surrounding the table are four light-colored chairs. Exposed wooden beams accent the ceiling, and natural light is filtered through large windows that lead into a comfortably furnished living space.
Home in Burlington
4.9 out of 5 average rating, 235 reviews

The Fleetwood Bungalow with Dreamy Porch

Welcome to The Fleetwood Inn! A charming, cozy one-bedroom bungalow in the heart of Burlington, Iowa. Right between our bustling business district and our nostalgic downtown, this little house has vast character. My favorite feature is all the original built-ins and beams. You will love the Western American inspiration and vintage finds, modern touches throughout, and dreamy details in every corner. Just added a Saatva Organic mattress for extra comfort.

Top guest favorite
A spacious kitchen area features a large sink set into a sleek countertop with a decorative gray stone finish. Large windows filter natural light, illuminating the brick wall and modern furnishings in the open layout. Potted plants add a touch of greenery.
Loft in Fort Madison
4.95 out of 5 average rating, 197 reviews

Beautiful Riverview Studio- steps away from Depot

Enjoy an exclusive view of the River, the FM Train Depot and Old Fort Madison from this 2nd floor true-studio apt. No cleaning fee for repeat and 5 star guests! The space has modern décor and all of the comforts of home. Railfans will enjoy the trains and river fans will enjoy the unique east-west river movement. There will be train sounds! The space comfortably sleeps two adults in its queen size Murphy bed. Please reach out with any questions.

Top guest favorite
Farm stay in Nauvoo
4.99 out of 5 average rating, 195 reviews

Nauvoo with a country view

We welcome guests to our 1880 Sonora Town Hall Cottage. This building once served as a voting poll for the Sonora Township. It is now a beautiful boutique cottage for overnight guests staying in the Nauvoo area. We are located on a working grain farm 6 miles southeast of Nauvoo. PLEASE NOTE: NO SMOKING or VAPING on the premises. We do have security cameras outside of the town hall building, which provide security and lighting for all guests.

Top guest favorite
A modern kitchen features white cabinetry and a large dining table surrounded by six chairs. Stainless steel appliances, including a refrigerator, add a contemporary touch. A ceiling fan hangs above, with sunlight filtering through the nearby windows, adorned with light curtains.
Religious building in Nauvoo
4.97 out of 5 average rating, 105 reviews

Nauvoo's Old Stone Church

Known as "The Old Stone Church," "The Legion Hall," "The Temple Stone Church," or "The Old Methodist Church," this building has a remarkable story to tell. Every group who has been in what is now Nauvoo, has played a part in its history. ​ It has now been thoroughly renovated, and serves as an elegant vacation home for those visiting Nauvoo, and looking for an historic experience, with all the modern luxuries.

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