Vacation rentals in Lee County

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Top-rated vacation rentals in Lee County

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Top guest favorite
The historic home features blue siding and a wide front porch adorned with festive garlands. Nestled among bare trees, the property showcases multi-story architecture, with a well-kept yard, providing a welcoming entrance. A gravel pathway leads toward the entrance of the home.
Vacation home in Carthage
4.94 out of 5 average rating, 162 reviews

Grandma Ruby's Vintage Victorian Downstairs Suite

This historic home built in 1884 has been completely renovated with loving care by a granddaughter with fond memories of magical times at her grandparents' unique home. With ten foot ceilings and beautiful craftsmanship, this spacious downstairs unit provides a master suite with a king sized bed and a big screen TV, a large kitchen, a queen bedroom, access to a large private back yard and plenty of parking. All conveniently located to town attractions and just 5 minutes from the interstate.

Top guest favorite
A charming green house stands surrounded by trees, featuring a sloped roof and an inviting orange door. A wooden deck extends from the front, with a rustic stone pathway leading up to the entrance. Stacked logs are arranged neatly in front.
Home in Nauvoo
4.96 out of 5 average rating, 55 reviews

Entire House - Horton Treehouse

Escape to a one-of-a-kind retreat nestled high in the trees — where comfort meets adventure & every window frames a postcard-worthy view of the Mississippi River. The home offers a magical experience. Inside, you’ll find a warm and inviting living space, a private Master Bedroom designed for rest and relaxation, and a spacious bathroom. The circular dining area & well-equipped kitchenette add charm & function, while the large outdoor deck is perfect for sipping coffee or stargazing at night.

Guest favorite
The cozy living area features a dark sofa positioned against a textured wall. A rustic wooden coffee table is centered on a patterned rug. Vintage nautical decor is displayed, including a ship's wheel and various framed art pieces. Soft lighting creates a warm ambiance.
Treehouse in Nauvoo
4.95 out of 5 average rating, 187 reviews

Captains Quarters Treehouse

An off the grid whimsical gem in the Ten Acre Treehouse forest! "The Captains Quarters". This is the 2nd treehouse in rural Nauvoo. A lot of the same touches found in "The Whitetail". The first treehouse here, you will find in this nautical inspired creation. This treehouse is a full 2 story, 400 sq foot, and features second story bedroom, sleeper sofa on the first floor, small kitchen area with refrigerator/freezer, microwave, coffee maker, plates, silverware, cups and a sink!

Top guest favorite
A spacious living area features a large leather sectional sofa, inviting relaxation. A wooden dining table with chairs is visible in the background, surrounded by shelves filled with books. Light enters through glass doors, enhancing the comfortable ambiance of the space.
Guest suite in Keokuk
4.96 out of 5 average rating, 532 reviews

Tree of Life River Retreat

Located 1½ miles north of Keokuk, nestled on a bluff overlooking the Mississippi River, the Tree of Life River retreat is located in a cozy, private, walk-out lower level (with hosts living above). There's a private bedroom with a queen bed and another sleeping area with four twin beds, perfect for one person or a family. Relax, enjoy nature, and take advantage of our large backyard. We are located approximately 18 miles from downtown Nauvoo via the bridge in Keokuk.

Top guest favorite
A single-story residence features a light exterior with a symmetrical layout. A covered entryway leads to large windows that allow natural light. A driveway extends toward a spacious two-car garage, surrounded by well-maintained grass and landscaped plants.
Home in Carthage
4.94 out of 5 average rating, 192 reviews

Nice 2 bedroom home w/attached garage & deck.

Nearby attractions in Carthage include historic Carthage Jail & Kibbe Museum, historical Carthage courthouse, public swimming pool & golf course, several public parks & library, shopping, restaurants, and the Legacy Theater. Many recreational activities & special events year round. Located just minutes from the interstate. 16 miles from Nauvoo, IL. 15 miles from Keokuk, IA. 27 miles from Macomb, IL. 43 miles from Quincy, IL. 59 miles from Hannibal, MO.

Top guest favorite
A living room features a leather sofa, two vintage armchairs, and a round ottoman, creating a cozy seating arrangement. Natural light enters through large windows framed with sheer curtains. Dark wooden flooring contrasts with the light-colored walls and decorative art pieces are displayed throughout.
Home in Burlington
4.91 out of 5 average rating, 253 reviews

The Fleetwood Bungalow with Dreamy Porch

Welcome to The Fleetwood Inn! A charming, cozy one-bedroom bungalow in the heart of Burlington, Iowa. Right between our bustling business district and our nostalgic downtown, this little house has vast character. My favorite feature is all the original built-ins and beams. You will love the Western American inspiration and vintage finds, modern touches throughout, and dreamy details in every corner. Just added a Saatva Organic mattress for extra comfort.

Top guest favorite
The kitchen features modern white cabinetry with black hardware and a marble countertop. A stainless steel refrigerator and oven are visible, along with a dark backsplash. An island with a sink and a black faucet provides additional prep space.
Loft in Fort Madison
4.95 out of 5 average rating, 222 reviews

Beautiful Riverview Studio- steps away from Depot

Enjoy an exclusive view of the River, the FM Train Depot and Old Fort Madison from this 2nd floor true-studio apt. No cleaning fee for repeat and 5 star guests! The space has modern décor and all of the comforts of home. Railfans will enjoy the trains and river fans will enjoy the unique east-west river movement. There will be train sounds! The space comfortably sleeps two adults in its queen size Murphy bed. Please reach out with any questions.

Superhost
The exterior of the house features a unique architectural design with a turret and a combination of stone and stucco walls. Multiple windows provide natural light, while the roof showcases varying angles and textures. Lush greenery surrounds the structure, enhancing the secluded feel.
Chalet in Nauvoo
4.68 out of 5 average rating, 272 reviews

View Nauvoo and the Mighty Mississippi / Sidon

Next to the Mississippi River and Close to LDS Temple & Visitors Center Hot tub Deck WIFI 3 fire places Antique claw foot bath tub inside a turret 2 kitchens 6 bunk beds 2 bed rooms Computer and printer Board Games Blue Tooth Speaker Taylor and Mini Taylor guitars Washer and Dryer Foosball Table Play Station 4 Digital grand piano Sacred Indian Burial Mounds in back yard We will consider pets if you are willing to keep them on the first floor only.

Top guest favorite
The front of the Sonora Town Hall Cottage features a white exterior with a welcoming entrance. A landscaped area filled with vibrant yellow flowers and greenery is seen in the foreground, while a scenic view of fields is visible in the background under a cloudy sunset.
Farm stay in Nauvoo
4.99 out of 5 average rating, 201 reviews

Nauvoo with a country view

We welcome guests to our 1880 Sonora Town Hall Cottage. This building once served as a voting poll for the Sonora Township. It is now a beautiful boutique cottage for overnight guests staying in the Nauvoo area. We are located on a working grain farm 6 miles southeast of Nauvoo. PLEASE NOTE: NO SMOKING or VAPING on the premises. We do have security cameras outside of the town hall building, which provide security and lighting for all guests.

Superhost
Home in Hamilton
5 out of 5 average rating, 3 reviews

Woodland Retreat High above the Mighty Mississippi

Wake up to sweeping views of the Mississippi River while surrounded by peaceful woods and abundant wildlife. Tucked away between Hamilton and Nauvoo, this private retreat offers the perfect balance of seclusion and convenience—just minutes from local attractions, dining, and the highway. Enjoy your morning coffee overlooking the river, spend the day exploring the area, and end the evening with unforgettable sunsets and starlit skies.

Top guest favorite
A modern kitchen features white cabinetry and a large dining table surrounded by six chairs. Stainless steel appliances, including a refrigerator, add a contemporary touch. A ceiling fan hangs above, with sunlight filtering through the nearby windows, adorned with light curtains.
Religious building in Nauvoo
4.97 out of 5 average rating, 120 reviews

Nauvoo's Old Stone Church

Known as "The Old Stone Church," "The Legion Hall," "The Temple Stone Church," or "The Old Methodist Church," this building has a remarkable story to tell. Every group who has been in what is now Nauvoo, has played a part in its history. ​ It has now been thoroughly renovated, and serves as an elegant vacation home for those visiting Nauvoo, and looking for an historic experience, with all the modern luxuries.

Guest favorite
The single-story cottage is surrounded by a spacious yard, bordered by trees. A gravel driveway leads to the house, which features a covered front porch with a white lattice design. The exterior is clad in light-colored siding, and a clear sky is visible overhead.
Cottage in Niota
4.83 out of 5 average rating, 287 reviews

Nauvoo Country Cottage - Sleeps 12

Relax in the quiet of the charming countryside surrounding Nauvoo, yet be close enough to enjoy all the local attractions within minutes. Nauvoo Country Cottage is located just 7.5 miles from the Nauvoo Illinois Temple. This cozy home sits on 3 acres giving plenty of privacy to your family or group.

Popular amenities for Lee County vacation rentals