Vacation rentals in Lee County

Grandma Ruby's Vintage Victorian Downstairs Suite

This historic home built in 1884 has been completely renovated with loving care by a granddaughter with fond memories of magical times at her grandparents' unique home. With ten foot ceilings and beautiful craftsmanship, this spacious downstairs unit provides a master suite with a king sized bed and a big screen TV, a large kitchen, a queen bedroom, access to a large private back yard and plenty of parking. All conveniently located to town attractions and just 5 minutes from the interstate.

Rusty Acres

Need a break from the hustle and bustle? Take a step back in time" just off the beaten path" . Over 1500 sq. ft. of comfort of old farmhouse charm in the lower level of our home. You have the benefit of a spacious family room/kitchen, two bedrooms each with a king size bed, Master bedroom has sleep number king mattress, one full bath with a washer/dryer unit and our unique binzebo to roast hot dogs or marshmallows with your family. Enjoy the peacefulness of country living and many amenities.

Entire House - Horton Treehouse

Escape to a one-of-a-kind retreat nestled high in the trees — where comfort meets adventure & every window frames a postcard-worthy view of the Mississippi River. The home offers a magical experience. Inside, you’ll find a warm and inviting living space, a private Master Bedroom designed for rest and relaxation, and a spacious bathroom. The circular dining area & well-equipped kitchenette add charm & function, while the large outdoor deck is perfect for sipping coffee or stargazing at night.

Captains Quarters Treehouse

An off the grid whimsical gem in the Ten Acre Treehouse forest! "The Captains Quarters". This is the 2nd treehouse in rural Nauvoo. A lot of the same touches found in "The Whitetail". The first treehouse here, you will find in this nautical inspired creation. This treehouse is a full 2 story, 400 sq foot, and features second story bedroom, sleeper sofa on the first floor, small kitchen area with refrigerator/freezer, microwave, coffee maker, plates, silverware, cups and a sink!

Tree of Life River Retreat

Located 1½ miles north of Keokuk, nestled on a bluff overlooking the Mississippi River, the Tree of Life River retreat is located in a cozy, private, walk-out lower level (with hosts living above). There's a private bedroom with a queen bed and another sleeping area with four twin beds, perfect for one person or a family. Relax, enjoy nature, and take advantage of our large backyard. We are located approximately 18 miles from downtown Nauvoo via the bridge in Keokuk.

cozy cottage

Tucked away in an area with quiet neighbors this serene cottage has a wonderful safe feeling. Close to historic downtown, the Mississippi, parks, the train station and the bridge, this is a great location. Twenty minutes from Nauvoo, this is one of the closest towns to Nauvoo with grocery stores and is just the right distance for the kids to fall asleep. With cobblestone roads and enchanting venues you are sure to fall in love with the Hallmark charm of Fort Madison.

Nice 2 bedroom home w/attached garage & deck.

Nearby attractions in Carthage include historic Carthage Jail & Kibbe Museum, historical Carthage courthouse, public swimming pool & golf course, several public parks & library, shopping, restaurants, and the Legacy Theater. Many recreational activities & special events year round. Located just minutes from the interstate. 16 miles from Nauvoo, IL. 15 miles from Keokuk, IA. 27 miles from Macomb, IL. 43 miles from Quincy, IL. 59 miles from Hannibal, MO.

Dr. Poepsel Building Airbnb

Second floor two Bedroom apartment located on the Southwest corner of the West Point City Square. Great location close to local bars, bowling alley, restaurants and grocery store. Appartment has outside deck great for viewing the annual West Point Sweet Corn Festival the second weekend of August. This appartment has a spacious kitchen and living room. Master bedroom has a king size bed, tv and walk-in closet. The spare bedroom has a closet and tv.

Beautiful Riverview Studio- steps away from Depot

Enjoy an exclusive view of the River, the FM Train Depot and Old Fort Madison from this 2nd floor true-studio apt. No cleaning fee for repeat and 5 star guests! The space has modern décor and all of the comforts of home. Railfans will enjoy the trains and river fans will enjoy the unique east-west river movement. There will be train sounds! The space comfortably sleeps two adults in its queen size Murphy bed. Please reach out with any questions.

View Nauvoo and the Mighty Mississippi / Sidon

Next to the Mississippi River and Close to LDS Temple & Visitors Center Hot tub Deck WIFI 3 fire places Antique claw foot bath tub inside a turret 2 kitchens 6 bunk beds 2 bed rooms Computer and printer Board Games Blue Tooth Speaker Taylor and Mini Taylor guitars Washer and Dryer Foosball Table Play Station 4 Digital grand piano Sacred Indian Burial Mounds in back yard We will consider pets if you are willing to keep them on the first floor only.

Nauvoo with a country view

We welcome guests to our 1880 Sonora Town Hall Cottage. This building once served as a voting poll for the Sonora Township. It is now a beautiful boutique cottage for overnight guests staying in the Nauvoo area. We are located on a working grain farm 6 miles southeast of Nauvoo. PLEASE NOTE: NO SMOKING or VAPING on the premises. We do have security cameras outside of the town hall building, which provide security and lighting for all guests.

Woodland Retreat High above the Mighty Mississippi

Wake up to sweeping views of the Mississippi River while surrounded by peaceful woods and abundant wildlife. Tucked away between Hamilton and Nauvoo, this private retreat offers the perfect balance of seclusion and convenience—just minutes from local attractions, dining, and the highway. Enjoy your morning coffee overlooking the river, spend the day exploring the area, and end the evening with unforgettable sunsets and starlit skies.