Vacation rentals in Lee County

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Top-rated vacation rentals in Lee County

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
Loft in Carthage
4.96 out of 5 average rating, 121 reviews

Huge Classy Upstairs Victorian Apt with Jetted Tub

The whole group will be comfortable in this spacious and unique space. With two queen sized beds and a set of twins under the attic skylights everyone will find a restful place to restore for the day. A relaxing jetted tub also provides a rainfall shower with 3 acupuncture jets. The kitchen is fully stocked with quality cookware. This vintage treasure was built in 1884 and is a completely renovated upstairs unit. There is 2 bedroom unit below this one and the option to share a washer/dryer.

Guest favorite
Cabin in Montrose
4.89 out of 5 average rating, 37 reviews

Grandpa's Fishing Cabin is Cozy!

Welcome to Grandpa’s Cozy Cabin, a peaceful retreat tucked right along the banks of the beautiful Mississippi River. A warm, rustic cabin with all the comforts of home, Gorgeous riverfront views perfect for sunrise coffee or sunset drinks, Outdoor seating, firepit, and space to unwind under the stars. A quiet, relaxing atmosphere. Great for a weekend getaway, family stay, or couple’s retreat. We offers the charm of simple living with the magic of the river right outside your door.

Top guest favorite
Guest suite in Keokuk
4.96 out of 5 average rating, 518 reviews

Tree of Life River Retreat

Located 1½ miles north of Keokuk, nestled on a bluff overlooking the Mississippi River, the Tree of Life River retreat is located in a cozy, private, walk-out lower level (with hosts living above). There's a private bedroom with a queen bed and another sleeping area with four twin beds, perfect for one person or a family. Relax, enjoy nature, and take advantage of our large backyard. We are located approximately 18 miles from downtown Nauvoo via the bridge in Keokuk.

Top guest favorite
An outdoor deck showcases a round table surrounded by four chairs with cushions. An additional chair is positioned nearby. A patterned rug lies beneath the table, providing a cozy area for relaxation. Distant green grass and trees can be seen in the background.
Home in Carthage
4.93 out of 5 average rating, 177 reviews

Nice 2 bedroom home w/attached garage & deck.

Nearby attractions in Carthage include historic Carthage Jail & Kibbe Museum, historical Carthage courthouse, public swimming pool & golf course, several public parks & library, shopping, restaurants, and the Legacy Theater. Many recreational activities & special events year round. Located just minutes from the interstate. 16 miles from Nauvoo, IL. 15 miles from Keokuk, IA. 27 miles from Macomb, IL. 43 miles from Quincy, IL. 59 miles from Hannibal, MO.

Guest favorite
A dining area features a round wooden table with a decorative bowl at its center. Surrounding the table are four light-colored chairs. Exposed wooden beams accent the ceiling, and natural light is filtered through large windows that lead into a comfortably furnished living space.
Home in Burlington
4.9 out of 5 average rating, 236 reviews

The Fleetwood Bungalow with Dreamy Porch

Welcome to The Fleetwood Inn! A charming, cozy one-bedroom bungalow in the heart of Burlington, Iowa. Right between our bustling business district and our nostalgic downtown, this little house has vast character. My favorite feature is all the original built-ins and beams. You will love the Western American inspiration and vintage finds, modern touches throughout, and dreamy details in every corner. Just added a Saatva Organic mattress for extra comfort.

Top guest favorite
A spacious kitchen area features a large sink set into a sleek countertop with a decorative gray stone finish. Large windows filter natural light, illuminating the brick wall and modern furnishings in the open layout. Potted plants add a touch of greenery.
Loft in Fort Madison
4.95 out of 5 average rating, 198 reviews

Beautiful Riverview Studio- steps away from Depot

Enjoy an exclusive view of the River, the FM Train Depot and Old Fort Madison from this 2nd floor true-studio apt. No cleaning fee for repeat and 5 star guests! The space has modern décor and all of the comforts of home. Railfans will enjoy the trains and river fans will enjoy the unique east-west river movement. There will be train sounds! The space comfortably sleeps two adults in its queen size Murphy bed. Please reach out with any questions.

Top guest favorite
Farm stay in Nauvoo
4.99 out of 5 average rating, 195 reviews

Nauvoo with a country view

We welcome guests to our 1880 Sonora Town Hall Cottage. This building once served as a voting poll for the Sonora Township. It is now a beautiful boutique cottage for overnight guests staying in the Nauvoo area. We are located on a working grain farm 6 miles southeast of Nauvoo. PLEASE NOTE: NO SMOKING or VAPING on the premises. We do have security cameras outside of the town hall building, which provide security and lighting for all guests.

Top guest favorite
The historic building is shown in a monochromatic view, presenting its stone exterior and simple architecture. A single tree stands nearby, with the road visible in the foreground. The structure features a gabled roof and a small cupola at the top.
Religious building in Nauvoo
4.97 out of 5 average rating, 105 reviews

Nauvoo's Old Stone Church

Known as "The Old Stone Church," "The Legion Hall," "The Temple Stone Church," or "The Old Methodist Church," this building has a remarkable story to tell. Every group who has been in what is now Nauvoo, has played a part in its history. ​ It has now been thoroughly renovated, and serves as an elegant vacation home for those visiting Nauvoo, and looking for an historic experience, with all the modern luxuries.

Guest favorite
Home in Nauvoo
4.84 out of 5 average rating, 116 reviews

Entire Rental House • Nauvoo Horton House

Relax with the whole family at The Horton House. It is a welcoming country home that is located on the edge of town with plenty of parking & room for the family. This fully remodeled home has all the comfort & peace you are looking for when arriving right as you enter into Nauvoo. Being here will allow you to enjoy quiet time with your family while also being able to still tour the town!

Guest favorite
Home in Fort Madison
4.83 out of 5 average rating, 6 reviews

Cottage on Third

Your perfect home away from home awaits. This charming cottage is professionally staged and thoughtfully designed for comfort and style. Enjoy a serene, inviting space with all the conveniences you need—from a fully equipped kitchen to cozy living areas. Every detail is covered, inside and out, so you can relax, unwind, and simply enjoy your stay.

Guest favorite
A cozy dining area features a light wood table surrounded by built-in benches, creating a simple and inviting space. A window allows natural light to brighten the room, while potted plants add a touch of greenery. The front door is visible, enhancing the sense of entry.
Guesthouse in Nauvoo
4.83 out of 5 average rating, 166 reviews

Carriage Cottage, Nauvoo Gem, Outstanding View

Nearby historic Nauvoo. On the river with a beautiful view and nature walks. Easy access to everything, convenient to all the historic sites. This cottage is perfect for a couple or a small family. It is professionally decorated and gives an ambiance of peace and comfort.

Top guest favorite
Earthen home in Nauvoo
4.97 out of 5 average rating, 86 reviews

Nauvoo Halfling House

Live like a Halfling in this fantasy getaway five minutes from historic Nauvoo Illinois! This bermed home is tucked into a hill in a small wooded glen, perfect for anyone looking to connect with nature or hibernate through the winter.

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